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Journal Articles

The Fetal Specific Gene LIN28B Is Essential for Human Fetal B-Lymphopoiesis and Initiation of KMT2A-AFF1+ Infant Acute Lymphoblastic Leukemia

Rebecca E Ling, Thomas Jackson, Natalina Elliott, Joe W Cross, Lucy Hamer, Arundhati S Wuppalapati, Alastair L Smith, Catherine M Chahrour, Okan Sevim, Deena Iskander, Guanlin Wang, Sorcha I O'Byrne, Siobhan Rice, Joe R Harman, Bethan Psaila, Rhys G Morgan, Irene Roberts, Thomas A Milne, Anindita Roy
Journal: Blood
Blood (2024) 144 (Supplement 1): 199.
https://doi.org/10.1182/blood-2024-198819
Published: 2024
Journal Articles

Differential Gene Expression in KMT2A::AFF1 Leukemia Is Driven By Enhancer Heterogeneity

Alastair L Smith, Nicholas Denny, Catherine M Chahrour, Natalina Elliott, Thomas Jackson, Joe Harman, Huimin Geng, Irene Roberts, Nicholas Crump, James Oliver Davies, Anindita Roy, Thomas A Milne
Journal: Blood
Blood (2024) 144 (Supplement 1): 201.
https://doi.org/10.1182/blood-2024-208035
Published: 2024
Journal Articles

Bispecific CAR-iNKT Immunotherapy for High Risk MLL-Rearranged Acute Lymphoblastic Leukemia

Hongwei Ren, Natalina Elliott, Bryan Lye, Joe Cross, Lucy Field, Kanagaraju Ponnusamy, Irene Roberts, Christina Halsey, Thomas Arthur Milne, Anindita Roy, Anastasios Karadimitris
Journal: Blood
Blood (2023) 142 (Supplement 1): 766.
https://doi.org/10.1182/blood-2023-186442
Published: 2023
Journal Articles

Human Bone Marrow Organoids Enable the Study of Hematopoietic Cell-Stromal Interactions and Support the Survival of Malignant Cells from Patients

Abdullah Khan, Antonio Rodriguez-Romera, Michela Colombo, Jasmeet S Reyat, Guanlin Wang, Wei Xiong Wen, Lauren C Murphy, Rebecca Ling, Natalina Elliott, Nikolaos Sousos, Samuel Kemble, Beata Grygielska, Christopher Mahoney, Andrew P. Stone, Adam P Croft, David Bassett, Gowsihan Poologasundarampillai, Adele K. Fielding, Emily A. Cutler, Anindita Roy, Sarah Gooding, Julie Rayes, Kellie Machlus, Bethan Psaila
Journal: Blood
Blood (2022) 140 (Supplement 1): 1679–1681.
https://doi.org/10.1182/blood-2022-164881
Published: 2022
Journal Articles

Epigenome-Wide Association Study of Acute Lymphoblastic Leukemia in Children with Down Syndrome

Shaobo Li, Pagna Sok, Keren Xu, Ivo S Muskens, Natalina Elliott, Swe Swe Myint, Priyatama Pandey, Helen M Hansen, Libby M Morimoto, Alice Y Kang, Catherine Metayer, Xiaomei Ma, Beth A Mueller, Anindita Roy, Irene Roberts, Karen R Rabin, Austin L Brown, Philip J. Lupo, Joseph L. Wiemels, Adam J. de Smith
Journal: Blood
Blood (2021) 138 (Supplement 1): 214.
https://doi.org/10.1182/blood-2021-151454
Published: 2021
Journal Articles

Sensitive, rapid diagnostic test for transient abnormal myelopoiesis and myeloid leukemia of Down syndrome

David Cruz Hernandez, Marlen Metzner, Anne Pieta de Groot, Batchimeg Usukhbayar, Natalina Elliott, Irene Roberts, Paresh Vyas
Journal: Blood
Blood (2020) 136 (12): 1460–1465.
https://doi.org/10.1182/blood.2020005610
Published: 2020
Includes: Supplemental data
Journal Articles

Trisomy 21 Driven Pro-Inflammatory Signalling in Fetal Bone Marrow May Play a Role in Perturbed B-Lymphopoiesis and Acute Lymphoblastic Leukemia of Down Syndrome

Sorcha Isabella O'Byrne, BSc, Natalina Elliott, PhD, Gemma Buck, BSc, Siobhan Rice, David O'Connor, Jana Oswald, Hannah Fuchs, Ella-Mae Labbett, Nicholas James Fordham, MBBS, BSc, Anindita Roy, MD PhD, Irene Roberts
Journal: Blood
Blood (2019) 134 (Supplement_1): 1206.
https://doi.org/10.1182/blood-2019-130180
Published: 2019
Journal Articles

Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs

Sorcha O’Byrne, Natalina Elliott, Siobhan Rice, Gemma Buck, Nicholas Fordham, Catherine Garnett, Laura Godfrey, Nicholas T. Crump, Gary Wright, Sarah Inglott, Peng Hua, Bethan Psaila, Benjamin Povinelli, David J. H. F. Knapp, Antonio Agraz-Doblas, Clara Bueno, Ignacio Varela, Phillip Bennett, Hashem Koohy, Suzanne M. Watt, Anastasios Karadimitris, Adam J. Mead, Phillip Ancliff, Paresh Vyas, Pablo Menendez, Thomas A. Milne, Irene Roberts, Anindita Roy
Journal: Blood
Blood (2019) 134 (13): 1059–1071.
https://doi.org/10.1182/blood.2019001289
Published: 2019
Includes: Supplemental data
Journal Articles

Mature Analysis of the Prospective Oxford Down Syndrome (DS) Cohort Study: Timing and Clinical Impact of Preleukemic GATA1 Mutations and Lessons for Management of Newborns with DS

Irene Roberts, MD, Neha Bhatnagar, ND, Amelie Chaussade, MD, Laure Nizery, MD, Helen Richmond, RSCN, Natalina Elliott, PhD, Gemma Buck, BSc, Marlen Metzner, MSc, Alison Kennedy, MSc, Catherine Garnett, Kelly Perkins, PhD, Paresh Vyas, DPhil, FRCP, FRCPath, MRCP, MRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 569.
https://doi.org/10.1182/blood.V130.Suppl_1.569.569
Published: 2017
Journal Articles

Molecular and Functional Characterization of Disease-Propagating Stem Cells in Juvenile Myelomonocytic Leukemia

Eleni Louka, MD, Benjamin Povinelli, PhD, Alba Rodriguez-Meira, Gemma Buck, BSc, Angela Hamblin, MD PhD, Christopher Booth, Anindita Roy, MD PhD, Natalina Elliott, PhD, Deena Iskander, MD, Josu de la Fuente, FRCP, PhD FRCPath, Nicholas James Fordham, MBBS, BSc, Sorcha Isabella Obyrne, Sarah Inglott, Anupama Gopala Rao, MB, MRCP, MRCPath, Irene Roberts, MD, Adam J Mead, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 379.
https://doi.org/10.1182/blood.V130.Suppl_1.379.379
Published: 2017
Journal Articles

Clinical and Hematologic Impact of Fetal and Perinatal Variables on Mutant GATA1 Clone Size in Neonates with Down Syndrome

Neha Bhatnagar, MBChB MRCPCH FRCPath, Kelly Perkins, Sarah Filippi, Helen Richmond, RN, Joanna Bonnici, Kate Alford, Georgina Hall, BSc, PhD MBBS, FRCP, FRCPath, Gaëtan Juban, PhD, Simon McGowan, Anindita Roy, MDPhD, Natalina Elliott, Michael Stumpf, Alice Norton, MB, Paresh Vyas, MDPhD, Irene Roberts, MDFRCP FRCPCH FRCPath
Journal: Blood
Blood (2014) 124 (21): 2349.
https://doi.org/10.1182/blood.V124.21.2349.2349
Published: 2014