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Batchimeg Usukhbayar
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Journal Articles

Clonal Basis of Resistance and Response to Ivosidenib Combination Therapies Is Established Early during Treatment in IDH1 -Mutated Myeloid Malignancies

Sven Turkalj, Bilyana Stoilova, Angus J Groom, Felix A Radtke, Rabea Mecklenbrauck, Niels Asger Jakobsen, Curtis A Lachowiez, Marlen Metzner, Batchimeg Usukhbayar, Mirian Angulo Salazar, Zhihong Zeng, Sanam Loghavi, Jennifer Marvin-Peek, Verena Körber, Farhad Ravandi, Ghayas C. Issa, Tapan M. Kadia, Vasiliki Symeonidou, Anne De Groot, Hagop M. Kantarjian, Koichi Takahashi, Marina Konopleva, Courtney D. DiNardo, Paresh Vyas
Journal: Blood
Blood (2024) 144 (Supplement 1): 642.
https://doi.org/10.1182/blood-2024-201970
Published: 2024
Journal Articles

GATA1 Target Gene CSF2RB Is Functionally Coupled to MPL and Marks a TPO-Dependent Preleukemic TAM Cell Population Sustained By the Fetal Liver but Not Bone Marrow

David Cruz Hernandez, Nicolas Papadopoulos, Elise Sepulchre, Marlen Metzner, Batchimeg Usukhbayar, Mirian Angulo Salazar, Leila Varghese, Gabriel Levy, Irene Roberts, Stefan N Constantinescu, Paresh Vyas
Journal: Blood
Blood (2023) 142 (Supplement 1): 404.
https://doi.org/10.1182/blood-2023-174449
Published: 2023
Journal Articles

Dysregulation of Stem-Progenitor and Differentiation Programmes through Modulation of Bivalent Chromatin Drives Leukemogenesis in Mutant IDH2 Acute Myeloid Leukaemia

Douglas RA RA Silveira, Prodromos Chatzikyriakou, Maria del Pilar Casares Alaez, Sarah Mackie, Roan Hulks, Olena Yavorska, Paulina Siejka-Zielinska, Marlen Metzner, Alastair Smith, Batchimeg Usukhbayar, Virginie Penard-Lacronique, Chunxiao Song, Anita K. Gandhi, Maroof Hasan, Paresh Vyas, Thomas A. Milne, Skirmantas Kriaucionis, Lynn Quek
Journal: Blood
Blood (2022) 140 (Supplement 1): 8698–8699.
https://doi.org/10.1182/blood-2022-165898
Published: 2022
Journal Articles

Genotyping of Multiple Genomic Loci with Chromatin Accessibility Profiling in Single Cells Links Clonal Hierarchy with Epigenetic Variation in Acute Myeloid Leukemia

Sven Turkalj, Niels Asger Jakobsen, Angus Groom, Marlen Metzner, Batchimeg Usukhbayar, Mirian Angulo Salazar, Kevin Clark, E. Ravza Gür, Lance D. Hentges, Paul Sopp, James O.J. Davies, Jim R. Hughes, Paresh Vyas
Journal: Blood
Blood (2022) 140 (Supplement 1): 1193–1194.
https://doi.org/10.1182/blood-2022-163139
Published: 2022
Journal Articles

Single-Cell Analysis of Human Clonal Hematopoiesis Identifies Distinct Impact of DNMT3A and TET2 mutations on Hematopoietic Differentiation

Niels Asger Jakobsen, Sven Turkalj, Bilyana Stoilova, Marlen Metzner, Rachel Moore, Batchimeg Usukhbayar, Mirian Angulo Salazar, Alison Kennedy, Simon Newman, Benjamin Kendrick, Adrian Taylor, Rasheed Afinowi-Luitz, Roger Gundle, Bridget Watkins, Kim Wheway, Debra Beazley, Andrew Carr, Paresh Vyas
Journal: Blood
Blood (2022) 140 (Supplement 1): 2227–2228.
https://doi.org/10.1182/blood-2022-166474
Published: 2022
Journal Articles

Graft Versus Leukaemia (GvL): Identification & Characterisation of Alloreactive Antigens and Cognate T Cell Responses in Acute Myeloid Leukemia

Connor Sweeney, Gerda Mickute, Kinam Gupta, Marlen Metzner, Batchimeg Usukhbayar, Maria Chiara Barbanti, Gavinda Sangha, Ronjon Chakraverty, Persephone Borrow, Nicola Ternette, Ane Ogbe, Maria Aggelakopoulou, Paresh Vyas
Journal: Blood
Blood (2022) 140 (Supplement 1): 1576–1578.
https://doi.org/10.1182/blood-2022-166918
Published: 2022
Journal Articles

Single Cell Characterisation of Transcriptional Programmes of Responsive and Resistant Leukaemic Progenitors in IDH2 -Mutant Acute Myeloid Leukaemia in the AG221-AML-005 Study

Prodromos Chatzikyriakou, Douglas RA Silveira, Maria del Pilar Casares Aláez, Batchimeg Usukhbayar, Marlen Metzner, Paresh Vyas, Anita K. Gandhi, Alberto Risueño, Maroof Hasan, Lynn Quek
Journal: Blood
Blood (2022) 140 (Supplement 1): 3414–3415.
https://doi.org/10.1182/blood-2022-163717
Published: 2022
Journal Articles

Dynamics of Clonal Hematopoiesis Inferred By Modelling Deep Bulk Whole-Genome Sequencing Data at a Single Time Point

Naser Ansari-Pour, Verena Körber, Niels Asger Jakobsen, Rachel Moore, Nina Claudino, Marlen Metzner, Batchimeg Usukhbayar, Mirian Angulo Salazar, Simon Newman, Benjamin Kendrick, Adrian Taylor, Rasheed Afinowi-Luitz, Roger Gundle, Bridget Watkins, Kim Wheway, Debra Beazley, Andrew Carr, Paresh Vyas, Thomas Höfer
Journal: Blood
Blood (2022) 140 (Supplement 1): 5753–5754.
https://doi.org/10.1182/blood-2022-166236
Published: 2022
Journal Articles

Sensitive, rapid diagnostic test for transient abnormal myelopoiesis and myeloid leukemia of Down syndrome

David Cruz Hernandez, Marlen Metzner, Anne Pieta de Groot, Batchimeg Usukhbayar, Natalina Elliott, Irene Roberts, Paresh Vyas
Journal: Blood
Blood (2020) 136 (12): 1460–1465.
https://doi.org/10.1182/blood.2020005610
Published: 2020
Includes: Supplemental data
Journal Articles

A Novel Model of Human Hemopoiesis Based on Single Cell Functional and Transcriptional Analysis of Lympho-Myeloid Progenitors

Bilyana Stoilova, PhD, Dimitris Karamitros, PhD, Zahra Aboukhalil, Fiona Hamey, Andreas Reinisch, MD PhD, Marina Samitsch, PhD, Lynn Quek, FRCPath, DPhil, MBBS, Georg Otto, PhD, Emmanouela Repapi, PhD, Jessica Doondeea, Batchimeg Usukhbayar, Julien Calvo, PhD, Stephen Taylor, PhD, Nicolas Goardon, PhD, Emmanuelle Six, Francoise Pflumio, PhD, Catherine Porcher, PhD, Ravi Majeti, MD PhD, Berthold Gottgens, PhD, Paresh Vyas, DPhil, FRCP, FRCPath, MRCP, MRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 2413.
https://doi.org/10.1182/blood.V130.Suppl_1.2413.2413
Published: 2017
Journal Articles

Functional and Genetic Heterogeneity of Distinct Leukemic Stem Cell Populations in CD34- Human Acute Myeloid Leukemia

Lynn Quek, Georg Otto, Catherine Garnett, Ludovic Lhermitte, I-Jun Lau, Dimitris Karamitros, Jessica Doondeea, Batchimeg Usukhbayar, Nicolas Goardon, Adam Ivey, Yisu Gu, Christopher G Allen, Rosemary E Gale, Benjamin Davies, Alexander Sternberg, Sally Killick, Hannah Hunter, Paul Cahalin, Andrew Price, Andrew Carr, Mike Griffiths, Paul Virgo, Stephen Mackinnon, David Grimwade, Sylvie D Freeman, Nigel Russell, Charles Craddock, MDPhD, Adam Mead, MDPhD, Andrew Peniket, MD, Catherine Porcher, Paresh Vyas
Journal: Blood
Blood (2014) 124 (21): 15.
https://doi.org/10.1182/blood.V124.21.15.15
Published: 2014