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Journal Articles

CLL Is Associated with Development of Subclinical Cytomegalovirus Viraemia and Accumulation of Large Populations of “exhausted” CMV-Specific CD4+ T Cells

Helen M Parry, Natasha Cutmore, Nikhil Mirajkar, Annette Pachnio, Tina McSkeane, Miriam Ciaurriz, Duncan Baird, Chris Pepper, Mike Griffiths, Guy Pratt, Paul Moss, MDPhD

Blood (2014) 124 (21): 3290.

https://doi.org/10.1182/blood.V124.21.3290.3290

Published: 2014

Journal Articles

Split Mixed Donor Chimerism Early after T-Cell Depleted Reduced Intensity Conditioned Allogeneic Haematopoietic Stem Cell Transplantation Predicts Survival

Francesca A M Kinsella, MBChB, PhD MRCP, Amy Gudger, MBBS, MRCP, Charlotte F Inman, PhD, Graham Mc Ilroy, MBChB, PhD, Sandeep Nagra, MD, Jane Nunnick, Dave Waldron, Kerry Wall, Mike Griffiths, Paul Moss, MDPhD, Charles Craddock, MDPhD, Emmanouil Nikolousis, PhD, Ram Malladi, MBBS, PhD MRCP

Blood (2014) 124 (21): 423.

https://doi.org/10.1182/blood.V124.21.423.423

Published: 2014

Journal Articles

CLL Progression Is Associated with Increased Clonal Diversity and Replication Stress

Angelo Agathanggelou, PhD, Anna Skowronska, PhD, Nick Davies, PhD, Marwan Kwok, MB ChB, MRCP, Samuel Clockie, Mike Griffiths, Alexander Taylor, Tatjana Stankovic, MD PhD

Blood (2014) 124 (21): 1977.

https://doi.org/10.1182/blood.V124.21.1977.1977

Published: 2014

Journal Articles

Functional and Genetic Heterogeneity of Distinct Leukemic Stem Cell Populations in CD34- Human Acute Myeloid Leukemia

Blood (2014) 124 (21): 15.

https://doi.org/10.1182/blood.V124.21.15.15

Published: 2014

Journal Articles

Cytomegalovirus Infection Is Associated with Expansions of CD8 T Cells and Highly Oligoclonal Vdelta1 Gamma/Delta T Cells in Patients Treated with Dasatinib for Chronic Myelogenous Leukaemia

David Lewis, Guy Pratt, David A Price, MRCP, DPhil, Tessa Holyoake, Kristin Ladell, PhD, Heather Jorgensen, PhD, Annette Pachnio, Mike Griffiths, Charles Craddock, MDPhD, Paul Moss, MDPhD

Blood (2014) 124 (21): 1814.

https://doi.org/10.1182/blood.V124.21.1814.1814

Published: 2014

Journal Articles

Targeted Treatments: Pre-Clinical Evaluation Of Efficacy By Tracking Clonal Diversity In CLL Xenograft Models

Nicholas J Davies, Ceri E Oldreive, PhD, Angelo Agathanggelou, Clive Gould, Guy Pratt, Mike Griffiths, Tatjana Stankovic, MD, PhD

Blood (2013) 122 (21): 875.

https://doi.org/10.1182/blood.V122.21.875.875

Published: 2013

Journal Articles

Survival Outcomes in Patients with FLT3 -Itd Positive Acute Myeloid Leukaemia Relative to Biological Stratification: Smaller FLT3 -Itd Clone Size Predict Better Overall Survival

Justin Ching Ting Loke, Susanna Akiki, Joanne Ewing, Syed W Bokhari, Deepak Chandra, Julie Arrazi, Peter Hazlewood, Katherine Arthur, Julie Walsh, Yvonne Membwange, Farooq Ahmad Wandroo, Angela Watts, Charles Craddock, Mike Griffiths, Manoj Raghavan

Blood (2012) 120 (21): 1460.

https://doi.org/10.1182/blood.V120.21.1460.1460

Published: 2012

Journal Articles

Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML)

Blood (2012) 119 (14): 3361–3369.

https://doi.org/10.1182/blood-2011-09-377044

Published: 2012

Includes: Supplemental data

Journal Articles

Deletion Size Influences Clinical Outcome In Patients with Chronic Lymphocytic Leukemia; 13q Deletion Anatomy, Cooperating Lesions and Cancer Pathogenesis

Helen Parker, PhD, Matthew JJ Rose-Zerilli, PhD, Anton Parker, BSc, Tracy Chaplin, Anne Catherine Gardiner, BSc, Mike Griffiths, Andrew Collins, PhD, Bryan D Young, BSc, PhD, David Graham Oscier, Jonathan C. Strefford, BSc, PhD

Blood (2010) 116 (21): 757.

https://doi.org/10.1182/blood.V116.21.757.757

Published: 2010

Journal Articles

Co-Existence of LMPP-Like and GMP-Like Leukemia Stem Cells In Acute Myeloid Leukemia

Blood (2010) 116 (21): 91.

https://doi.org/10.1182/blood.V116.21.91.91

Published: 2010

Journal Articles

Analysis of BCR-ABL1 Tyrosine Kinase Domain Mutations In Primitive Chronic Myeloid Leukemia Cells Identifies a Unique Mutator Phenotype.

Xiaoyan Jiang, MD, PhD, Hannah Grant, PhD, Justin Stebbing, MD, PhD, Letizia Foroni, MD, Charles Craddock, BM, MRCP, MRCPah, MD, Mike Griffiths, MD, Richard E. Clark, MBBS, MD, FRCP, FRCPath, Stephen O'Brien, MD, PhD, Jamshid S. Khorashad, MD, PhD, Gareth Gerrard, MD, PhD, Lihui Wang, MD, PhD, Julie Irving, PhD, Meng Wang, PhD, Loraine Karran, MD, Martin JS Dyer, MA, DPhil, FRCP, FRCPath, Donna L. Forrest, MD, Karen Page, MA, PhD, Connie J. Eaves, PhD, Adrian Woolfson, PhD

Blood (2010) 116 (21): 3397.

https://doi.org/10.1182/blood.V116.21.3397.3397

Published: 2010

Journal Articles

Deregulated expression of cytokine receptor gene, CRLF2 , is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia

Blood (2009) 114 (13): 2688–2698.

https://doi.org/10.1182/blood-2009-03-208397

Published: 2009

Includes: Supplemental data

Journal Articles

Pretransplant Characteristics Could Predict Full Donor Chimerism on Day +90 and Day +180 and Outcomes in Reduced Intensity Alemtuzumab Conditioning Allogeneic Transplantation Can Be Influenced by Chimeric Status

Emmanouil Nikolousis, Charles F. Craddock, BM, MRCP, MRCPath, Shankaranarayana Paneesha, MD, Sudhir Tauro, Prem Mahendra, II, Mark Cook, Fiona Clark, Richard Lovell, Sridhar Chaganti, Donald Milligan, MD, MBChB, Dominique Mcmullan, Mike Griffiths, Stephen P Robinson, MD

Blood (2008) 112 (11): 4409.

https://doi.org/10.1182/blood.V112.11.4409.4409

Published: 2008

Journal Articles

5′ Azacitidine in Combination with Valproic Acid Induces Complete Remissions in Patients with Advanced Acute Myeloid Leukaemia but Does Not Eradicate Clonal Leukaemic Stem/Progenitor Cells.

Charles Craddock, BM, DPhil, FRCP, FRCPath, Nicolas Goardon, Mike Griffiths, James D. Cavenagh, MD, Shamyla Siddique, Paresh Vyas, BM, DPhil, FRCP, FRCPath

Blood (2008) 112 (11): 945.

https://doi.org/10.1182/blood.V112.11.945.945

Published: 2008

Journal Articles

Donor Lymphocyte Infusion Is an Effective Management of Increasing Mixed Chimerism, and High Risk Disease with Minimal Side Effects.

Geothy Kochethu, Leena Karnik, Ginny Turner, Mike Griffiths, Mark Velangi, Sarah Lawson, Phil Darbyshire

Blood (2006) 108 (11): 3672.

https://doi.org/10.1182/blood.V108.11.3672.3672

Published: 2006

Journal Articles

A Broad Distribution of ZAP-70 Expression Is Demonstrated in Adult Acute Lymphoblastic Leukaemia by Quantitative PCR Analysis.

Geothy Kochethu, Andy Bell, Mike Griffiths, Gulnaz Begum, Farooq Wandroo, Paul A.H. Moss

Blood (2006) 108 (11): 4309.

https://doi.org/10.1182/blood.V108.11.4309.4309

Published: 2006

Journal Articles

The Relationship between Host Antigen-Presenting Cells and Graft-versus-Host Responses Following Human Nonmyeloablative Transplantation.

Fiona J. Clark, Mike Griffiths, Matt Collin, Prem Mahendra, Charles Craddock, Graham Jackson, Don Milligan, Paul A. Moss, Ronjon Chakraverty

Blood (2004) 104 (11): 2252.

https://doi.org/10.1182/blood.V104.11.2252.2252

Published: 2004

Journal Articles

Apoptotic resistance to ionizing radiation in pediatric B-precursor acute lymphoblastic leukemia frequently involves increased NF-κB survival pathway signaling

Victoria J. Weston, Belinda Austen, Wenbin Wei, Eliot Marston, Azra Alvi, Sarah Lawson, Philip J. Darbyshire, Mike Griffiths, Frank Hill, Jill R. Mann, Paul A. H. Moss, A. Malcolm R. Taylor, Tatjana Stankovic

Blood (2004) 104 (5): 1465–1473.

https://doi.org/10.1182/blood-2003-11-4039

Published: 2004

Journal Articles

Chronic graft-versus-host disease is associated with increased numbers of peripheral blood CD4 + CD25 high regulatory T cells

Fiona J. Clark, Richard Gregg, Karen Piper, Debbie Dunnion, Lisa Freeman, Mike Griffiths, Gulnaz Begum, Premini Mahendra, Charles Craddock, Paul Moss, Ronjon Chakraverty

Blood (2004) 103 (6): 2410–2416.

https://doi.org/10.1182/blood-2003-06-2073

Published: 2004

NARROW

CLL Is Associated with Development of Subclinical Cytomegalovirus Viraemia and Accumulation of Large Populations of “exhausted” CMV-Specific CD4+ T Cells

Split Mixed Donor Chimerism Early after T-Cell Depleted Reduced Intensity Conditioned Allogeneic Haematopoietic Stem Cell Transplantation Predicts Survival

CLL Progression Is Associated with Increased Clonal Diversity and Replication Stress

Functional and Genetic Heterogeneity of Distinct Leukemic Stem Cell Populations in CD34- Human Acute Myeloid Leukemia

Cytomegalovirus Infection Is Associated with Expansions of CD8 T Cells and Highly Oligoclonal Vdelta1 Gamma/Delta T Cells in Patients Treated with Dasatinib for Chronic Myelogenous Leukaemia

Targeted Treatments: Pre-Clinical Evaluation Of Efficacy By Tracking Clonal Diversity In CLL Xenograft Models

Survival Outcomes in Patients with FLT3 -Itd Positive Acute Myeloid Leukaemia Relative to Biological Stratification: Smaller FLT3 -Itd Clone Size Predict Better Overall Survival

Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML)

Deletion Size Influences Clinical Outcome In Patients with Chronic Lymphocytic Leukemia; 13q Deletion Anatomy, Cooperating Lesions and Cancer Pathogenesis

Co-Existence of LMPP-Like and GMP-Like Leukemia Stem Cells In Acute Myeloid Leukemia

Analysis of BCR-ABL1 Tyrosine Kinase Domain Mutations In Primitive Chronic Myeloid Leukemia Cells Identifies a Unique Mutator Phenotype.

Deregulated expression of cytokine receptor gene, CRLF2 , is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia

Pretransplant Characteristics Could Predict Full Donor Chimerism on Day +90 and Day +180 and Outcomes in Reduced Intensity Alemtuzumab Conditioning Allogeneic Transplantation Can Be Influenced by Chimeric Status

5′ Azacitidine in Combination with Valproic Acid Induces Complete Remissions in Patients with Advanced Acute Myeloid Leukaemia but Does Not Eradicate Clonal Leukaemic Stem/Progenitor Cells.

Donor Lymphocyte Infusion Is an Effective Management of Increasing Mixed Chimerism, and High Risk Disease with Minimal Side Effects.

A Broad Distribution of ZAP-70 Expression Is Demonstrated in Adult Acute Lymphoblastic Leukaemia by Quantitative PCR Analysis.

The Relationship between Host Antigen-Presenting Cells and Graft-versus-Host Responses Following Human Nonmyeloablative Transplantation.

Apoptotic resistance to ionizing radiation in pediatric B-precursor acute lymphoblastic leukemia frequently involves increased NF-κB survival pathway signaling

Chronic graft-versus-host disease is associated with increased numbers of peripheral blood CD4 + CD25 high regulatory T cells

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American Society of Hematology

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American Society of Hematology

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