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Journal Articles

Pirtobrutinib, a Highly Selective, Non-Covalent (Reversible) BTK Inhibitor in Relapsed / Refractory Marginal Zone Lymphoma: Results from Phase 1/2 BRUIN Study

Krish Patel, Julie M. Vose, Sunita D. Nasta, Jennifer R. Brown, Kami J. Maddocks, Jennifer A. Woyach, Nirav N. Shah, Bita Fakhri, Benoit Tessoulin, Shuo Ma, Deepa Jagadeesh, Ewa Lech-Maranda, Catherine C. Coombs, Manish Patel, Joanna M. Rhodes, Chaitra S Ujjani, Marc S. Hoffmann, Chan Y Cheah, Talha Munir, David Lewis, Lydia Scarfo, Toby A. Eyre, Alvaro J. Alencar, Jonathon B. Cohen, Andrew D. Zelenetz, Donald E. Tsai, Mei Li, Faith Bian, Paolo Abada, Pier Luigi Zinzani
Journal: Blood
Blood (2023) 142 (Supplement 1): 1660.
https://doi.org/10.1182/blood-2023-180048
Published: 2023
Journal Articles

Epcoritamab SC + GemOx Leads to High Complete Metabolic Response Rates in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma Ineligible for Autologous Stem Cell Transplant: Updated Results from Epcore NHL-2

Joshua Brody, Judit Mészáros Joergensen, David Belada, Regis T. Costello, Marek Trněný, Umberto Vitolo, David Lewis, Yasmin H. Karimi, Anna Maria Sureda Balari, Marc André, Björn E. Wahlin, Pieternella Lugtenburg, Faith Galderisi, Aqeel Abbas, Yaou Song, Malene Risum, Raul Cordoba
Journal: Blood
Blood (2023) 142 (Supplement 1): 3092.
https://doi.org/10.1182/blood-2023-180246
Published: 2023
Journal Articles

Initial Findings from a First-in-Human Phase 1a/b Trial of NX-5948, a Selective Bruton's Tyrosine Kinase (BTK) Degrader, in Patients with Relapsed/Refractory B Cell Malignancies

Emma Searle, Francesco Forconi, Kim Linton, Alexey Danilov, Pam McKay, David Lewis, Dima El-Sharkawi, Mary Gleeson, John Riches, Sarah G. Injac, Ted Shih, Srinand Nandakumar, May Tan, Ganesh Cherala, Erin Meredith, Graham P. Collins
Journal: Blood
Blood (2023) 142 (Supplement 1): 4473.
https://doi.org/10.1182/blood-2023-179508
Published: 2023
Journal Articles

Epcoritamab SC Monotherapy Leads to Deep and Durable Responses in Patients with Relapsed or Refractory Follicular Lymphoma: First Data Disclosure from the Epcore NHL-1 Follicular Lymphoma Dose-Expansion Cohort

Kim Linton, Wojciech Jurczak, Pieternella Lugtenburg, Emmanuel Gyan, Anna Maria Sureda Balari, Jacob Haaber Christensen, Brian Hess, Hervé Tilly, Raul Cordoba, David Lewis, Craig Okada, Martin Hutchings, Michael Roost Clausen, Umberto Vitolo, Tara Cochrane, Sirpa Leppa, Martine E.D. Chamuleau, Rebekah Conlon, Elena Favaro, Diana Gernhardt, Isil Altintas, Yan Liu, Catherine Thieblemont
Journal: Blood
Blood (2023) 142 (Supplement 1): 1655.
https://doi.org/10.1182/blood-2023-179887
Published: 2023
Journal Articles

Pirtobrutinib in Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL) Patients with Prior cBTKi: Safety and Efficacy Including High-Risk Subgroup Analyses from the Phase 1/2 BRUIN Study

Jonathon B. Cohen, Nirav N. Shah, Wojciech Jurczak, Pier Luigi Zinzani, Chan Y. Cheah, Toby A. Eyre, Chaitra S Ujjani, Youngil Koh, Won Seog Kim, Sunita D. Nasta, Ian W. Flinn, Benoit Tessoulin, Shuo Ma, Alvaro J. Alencar, David Lewis, Jennifer A. Woyach, Kami J. Maddocks, Krish Patel, Yucai Wang, Joanna M. Rhodes, Constantine S. Tam, John F. Seymour, Hirokazu Nagai, Julie M. Vose, Bita Fakhri, Marc S. Hoffmann, Francisco J. Hernandez-Ilizaliturri, Andrew D. Zelenetz, Anita Kumar, Talha Munir, Donald E. Tsai, Minna Balbas, Bin Liu, Amy S. Ruppert, Bastien Nguyen, Lindsey E. Roeker, Michael L. Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 981.
https://doi.org/10.1182/blood-2023-181627
Published: 2023
Journal Articles

Pirtobrutinib in Richter Transformation: Updated Efficacy and Safety Results with 18-Month Median Survival Follow-up from the Phase 1/2 BRUIN Study

William G. Wierda, Nirav N. Shah, Chan Yoon Cheah, David Lewis, Marc S. Hoffmann, Catherine C. Coombs, Nicole Lamanna, Shuo Ma, Deepa Jagadeesh, Talha Munir, Yucai Wang, Toby A. Eyre, Joanna M. Rhodes, Matthew McKinney, Ewa Lech-Maranda, Constantine S. Tam, Wojciech Jurczak, Koji Izutsu, Alvaro J. Alencar, Manish Patel, John F. Seymour, Jennifer A. Woyach, Lindsey E. Roeker, Philip A. Thompson, Paolo Abada, Caleb Ho, Narasimha Marella, Chunxiao Wang, Amy S. Ruppert, Binoj Chandrasekharan Nair, Hui Liu, Donald E. Tsai, Paolo Ghia
Journal: Blood
Blood (2023) 142 (Supplement 1): 1737.
https://doi.org/10.1182/blood-2023-181108
Published: 2023
Journal Articles

Characterizing EBV-associated lymphoproliferative diseases and the role of myeloid-derived suppressor cells

Paul J. Collins, Christopher P. Fox, Lindsay George, Hayden Pearce, Gordon Ryan, Carmela De Santo, Francis Mussai, David Lewis, Heather Long, Claire Shannon-Lowe
Journal: Blood
Blood (2021) 137 (2): 203–215.
https://doi.org/10.1182/blood.2020005611
Published: 2021
Includes: Supplemental data
Journal Articles

A Phase I/II Dose-Escalation Study of Thiotepa-Based Immunochemotherapy in Relapsed/Refractory Primary Central Nervous System Lymphoma; The Tier Trial

Christopher P Fox, MBChB(Hons), MRCP, FRCPath, PhD, Ayesha S Ali, MSc, Dorothee Auer, MD DM, PhD, Steffi Thust, MD FRCR, Aimee E Jackson, MSc, Louise Hopkins, BSc, MRes, Catherine Thomas, PhDBSc, Nicolas Martinez-Calle, MD MSc, Graham P. Collins, MA, MBBS, MRCP, FRCPath, DPhil, Shireen Kassam, MD, Josh Wright, MD, David Lewis, PhD FRCPath, BSc, Andres JM Ferreri, MD, Sridhar Chaganti, MDPhDMRCP,FRCPath, Jeffery Smith, MBChB BMedSci MRCP FRCPath, Kim Linton, MBChB PhD, Ian Chau, MD, Dominic J. Culligan, MD, Andrew Davies, MD PhD, Roderick Johnson, MD, Kate Cwynarski, PhDMD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2879.
https://doi.org/10.1182/blood-2019-122830
Published: 2019
Journal Articles

Ibrutinib at First Relapse for Mantle Cell Lymphoma: A United Kingdom Real World Analysis of Outcomes in 169 Patients

Rory McCulloch, FRCPath, MRCP, MBBS, Simon Rule, Toby A. Eyre, Harshita Goradia, Simon Bolam, MD, Thomas Creasey, MBBS, David Tucker, MD, Michelle Furtado, Oliver Miles, Samuel Harrison, Amir Shenouda, Andrew Robinson, Matthew Wilson, MD BSc, MRCP, Annabel McMillan, Nimish Shah, Graham McIlroy, MD, David Dutton, MD, Adam Bond, Luke Attwell, Alexander Langridge, Helen Parry, MB ChB, MRCP, PhD, John Willan, Gavin Campbell, FRCP,FRCPath, Deborah Turner, David Lewis, PhD FRCPath, BSc, Helen McCarthy, MBBS, PhD, Jonathan Lambert, Pamela McKay, MD, Neil Phillips, Shankara Paneesha, MD, Wendy Osborne, MD, Mark Bishton, Nicola Crosbie
Journal: Blood
Blood (2019) 134 (Supplement_1): 3993.
https://doi.org/10.1182/blood-2019-125947
Published: 2019
Journal Articles

Atypical Immunophenotype Predicts Worse Prognosis in Adult T-Cell Lymphoma/Leukemia: A Retrospective Study of 63 Caribbean Patients at a New York City Tertiary Center

Bachar Samra, MD, Edwin Chiu, MD, Bo Lin, MD PhD, Eric Tam, MD BS, Babak Baseri, MD MS, Iuliana Shapira, MD, Jason Gonsky, MD PhD, Robert David Lewis, MD, Gurinder Sidhu, MD, Ahmed Sawas, MD, Evelyn O. Taiwo, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2906.
https://doi.org/10.1182/blood-2018-99-111208
Published: 2018
Journal Articles

Real-World Outcomes of Older Patients with Primary Central Nervous System Lymphoma (PCNSL): Methotrexate Dose Intensity and Combination with Cytarabine Correlate with Response and Survival

Nicolas Martinez-Calle, MD #, Edward Poynton, Alia Alchawaf, MD, Shireen Kassam, MD, Matthew Horan, MD, Mark Rafferty, MBBS, BSc, Phillipa Kelsey, MD, Gemma Scott, MD, Stephanie Bruce, MD, Hannah Buckley, MD, Sophie Jones, MD, Yeong Jer Lim, MD, Ngu Loretta, MD, David Lewis, MD, Thankamma Ajithkumar, MD, Dominic J. Culligan, Clare Rowntree, MD, Josh Wright, MD, Pamela McKay, MD, Samih Fourali, MD, Toby A. Eyre, Jeffrey Smith, MD, Wendy Osborne, MD, Deborah Yallop, MBBS FRCP FRCPath PhD, Kim Linton, MBChB PhD, Christopher P. Fox, MD PhD, Kate Cwynarski, MD PhD # (#Shared authorship)
Journal: Blood
Blood (2018) 132 (Supplement 1): 572.
https://doi.org/10.1182/blood-2018-99-111901
Published: 2018
Journal Articles

Comparison of Disposition and Complications in Geriatric (≥ 65 years) and Non-Geriatric (50-64 years) Cancer Patients Receiving Hematopoietic Stem Cell Transplantation

Achuta Kumar Guddati, MD PhD, Gagan Kumar, MD MS, Robert David Lewis, MD, Iuliana Shapira, MD
Journal: Blood
Blood (2016) 128 (22): 2408.
https://doi.org/10.1182/blood.V128.22.2408.2408
Published: 2016
Journal Articles

Cytomegalovirus Infection Is Associated with Expansions of CD8 T Cells and Highly Oligoclonal Vdelta1 Gamma/Delta T Cells in Patients Treated with Dasatinib for Chronic Myelogenous Leukaemia

David Lewis, Guy Pratt, David A Price, MRCP, DPhil, Tessa Holyoake, Kristin Ladell, PhD, Heather Jorgensen, PhD, Annette Pachnio, Mike Griffiths, Charles Craddock, MDPhD, Paul Moss, MDPhD
Journal: Blood
Blood (2014) 124 (21): 1814.
https://doi.org/10.1182/blood.V124.21.1814.1814
Published: 2014
Journal Articles

Activation Of Natural Killer Cells By Soypeptide Lunasin and Cytokine: Implication In Cancer Immunotherapy For Lymphoma

Chun-Yu Tung, DVM, MS, Sharifah Kyazike, David Lewis, BA, MS, Ling Han, Alexander Kolb, MS, David Pelloso, Anthony Sinn, Karen E. Pollok, PhD, Shivani Srivastava, MD, Michael J. Robertson, MD, Hua-Chen Chang, PhD
Journal: Blood
Blood (2013) 122 (21): 1042.
https://doi.org/10.1182/blood.V122.21.1042.1042
Published: 2013
Journal Articles

Cidofovir Is a Highly Effective and Safe Salvage Therapy in Ganciclovir Resistant Cytomegalovirus Reactivation Following Allogeneic Haematopoietic Stem Cell Transplantation

David Lewis, Francesca Farina, Sandeep Nagra, Sridhar Chaganti, Annette Pachnio, PhD, Jane Nunnick, Paul AH Moss, MD PhD, Ram Malladi, Charles F. Craddock, BM, MRCP, MRCPath
Journal: Blood
Blood (2012) 120 (21): 1923.
https://doi.org/10.1182/blood.V120.21.1923.1923
Published: 2012