Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 21

Sort by

Sort Order Select

Journal Articles

Extended Intensified Consolidation and Maintenance Improve Ultra High-Risk Multiple Myeloma Patient Outcome - Long-Term Follow-up of the Ukmra Optimum/Muknine Trial

Blood (2024) 144 (Supplement 1): 3354.

https://doi.org/10.1182/blood-2024-201086

Published: 2024

Journal Articles

Age-Associated Macrophage Polarization to an M2 Phenotype Drives Myeloma Proliferation in the Aged Bone Marrow By Loss of Tumor-Associated Phagocytosis

Dominic James Fowler-Shorten, Charlotte Hellmich, Annalisa Altera, Rebecca S Maynard, Katherine Hampton, Matthew Markham, Alyssa Nicole Polski-Delve, Kristian Bowles, Stuart A Rushworth

Blood (2024) 144 (Supplement 1): 1893.

https://doi.org/10.1182/blood-2024-194721

Published: 2024

Journal Articles

Repolarisation of M2 Macrophages Via Cgas-Sting Activation Enhances Phagocytosis of Acute Myeloid Leukaemia

Matthew Markham, Rebecca S Maynard, George Bell, Katherine Hampton, Dominic James Fowler-Shorten, Alyssa Nicole Polski-Delve, Annalisa Altera, Rosie Taylor, Charlotte Hellmich, Kristian Bowles, Stuart A Rushworth

Blood (2024) 144 (Supplement 1): 4113.

https://doi.org/10.1182/blood-2024-205265

Published: 2024

Journal Articles

Efficacy and Tolerability of Trametinib in Adults with Histiocytic Neoplasms

Rodothea Amerikanou, Tahla Munir, Kristian Bowles, Christopher McNamara, Nikesh Dhiraj Chavda, Azeem Ahmed, Jagdish Adiyodi, Alasdair Coles, Philippa Kelsey, Jeffery Smith, Richard Adams, Hayder KA Hussein, Rui Zhao, Amelia Taylor, Trung Nguyen, Satyen Gohil, Matthew Collin

Blood (2024) 144 (Supplement 1): 1802.

https://doi.org/10.1182/blood-2024-204648

Published: 2024

Journal Articles

PAI-1 Mediates the Switch in Free Fatty Acid Metabolism from the Liver to the Bone Marrow to Support Hematopoietic Stem and Progenitor Cell Expansion during the Initial Stages of Infection

Katherine Hampton, Jayna J Mistry, Rebecca S Maynard, Alyssa Nicole Polski-Delve, Dominic Fowler-Shorten, Charlotte Hellmich, Naiara Beraza, Kristian Bowles, Stuart A Rushworth

Blood (2024) 144 (Supplement 1): 5662.

https://doi.org/10.1182/blood-2024-209758

Published: 2024

Journal Articles

A Prospective Analysis of Outcomes Following Successive Lines of Treatment in Mantle Cell Lymphoma in an Unselected Previously Untreated Population: The UK MCL Biobank

Sarah Mant, Georgina Naylor, Nicola Crosbie, Sree Aroori, Mark J Bishton, Kristian Bowles, Safia Dawi, Toby A. Eyre, Wendy Ingram, Abigail Martin, Christopher McNamara, Melanie Oates, Andrew Pettitt, Claire Scully, Brian Wainman, Mark Warner, Simon Rule, David John Lewis

Blood (2024) 144 (Supplement 1): 1641.

https://doi.org/10.1182/blood-2024-209701

Published: 2024

Journal Articles

Acute Myeloid Leukemia Induces an Increased Senescent Phenotype in the Large Intestine Which Protects Barrier Function and Reduces Leakiness

Katherine Hampton, Alyssa Nicole Polski-Delve, Rebecca S Maynard, Kristian Bowles, Naiara Beraza, Stuart A Rushworth

Blood (2024) 144 (Supplement 1): 6125.

https://doi.org/10.1182/blood-2024-209897

Published: 2024

Journal Articles

Sting Activation in Bone Marrow Macrophages Targets AML Blasts for Phagocytosis in an ICAM-1 Dependent Mechanism

Ravindu De Silva, Matthew Markham, Rebecca S Maynard, Katherine Hampton, Charlotte Hellmich, Dominic Fowler-Shorten, Kristian Bowles, Stuart Rushworth

Blood (2023) 142 (Supplement 1): 1597.

https://doi.org/10.1182/blood-2023-185880

Published: 2023

Journal Articles

Sphingomyelinase Regulates the Release of Protumoral Mitochondria Containing-Vesicles from AML Cells

Matthew Markham, David Riley, Rebecca S Maynard, Katherine Hampton, Ravindu De Silva, Charlotte Hellmich, Kristian Bowles, Stuart Rushworth

Blood (2023) 142 (Supplement 1): 4337.

https://doi.org/10.1182/blood-2023-186059

Published: 2023

Journal Articles

The Aging Bone Marrow Niche Disrupts Glutamine Metabolism By Upregulating HSC Derived Glutamine Synthetase

Charlotte Hellmich, Edyta E Wojtowicz, Dominic Fowler-Shorten, Rebecca S Maynard, Katherine Hampton, Iain Macaulay, Kristian Bowles, Stuart Rushworth

Blood (2023) 142 (Supplement 1): 1304.

https://doi.org/10.1182/blood-2023-180194

Published: 2023

Journal Articles

AML Inhibits Lipid Uptake By the Liver through an HGF/c-MET Dependent Mechanism Which Results in an Increased Supply of Free Fatty Acid to the Tumor

Rebecca S Maynard, Charlotte Hellmich, Katherine Hampton, Dominic Fowler-Shorten, Matthew Markham, Annalisa Altera, Thomas Flint, Ravindu De Silva, Naiara Beraza, Kristian Bowles, Stuart Rushworth

Blood (2023) 142 (Supplement 1): 6031.

https://doi.org/10.1182/blood-2023-178574

Published: 2023

Journal Articles

Acute Myeloid Leukemia Driven IL-3 Dependent Upregulation of BCL-2 in Non-Malignant Hematopoietic Progenitor Cells Increases Venetoclax Induced Cytopenias

Dominic Fowler-Shorten, Rebecca S Maynard, Katherine Hampton, Martha Ehikioya, Edyta E Wojtowicz, Kristian Bowles, Stuart Rushworth, Charlotte Hellmich

Blood (2023) 142 (Supplement 1): 293.

https://doi.org/10.1182/blood-2023-173835

Published: 2023

Journal Articles

IL-6 Mediates a Switch in Free Fatty Acid Metabolism from the Liver to the Bone Marrow to Support HSC Expansion during Infection

Katherine Hampton, Jayna Mistry, Rebecca S Maynard, Dominic Fowler-Shorten, Charlotte Hellmich, Naiara Beraza, Kristian Bowles, Stuart Rushworth

Blood (2023) 142 (Supplement 1): 1332.

https://doi.org/10.1182/blood-2023-178618

Published: 2023

Journal Articles

Multiple Myeloma Induced IL-6 Reprograms Lipid Metabolism through a CD36 Dependent Mechanism

Martha Ehikioya, Annalisa Altera, Katherine Hampton, Rebecca S Maynard, Dominic Fowler-Shorten, Charlotte Hellmich, Kristian Bowles, Matthew Markham, Ravindu De Silva, Stuart Rushworth

Blood (2023) 142 (Supplement 1): 6566.

https://doi.org/10.1182/blood-2023-177900

Published: 2023

Journal Articles

Stressed Hematopoiesis Induces Mitochondrial Trafficking to Hematopoietic Stem Cells

Jayna J Mistry, BSc, Christopher Richard Marlein, BSc, Iain Macauley, PhD BSc, Rebecca H Horton, Adam Morfakis, BSc, Charlotte Hellmich, MBBChir, BSc, MRCP, Anna Haestier, Bsc, PgD MBBS, MRCOG, Kristian Bowles, MBBS, PhD, Stuart Rushworth, PhD BSc

Blood (2018) 132 (Supplement 1): 3849.

https://doi.org/10.1182/blood-2018-99-110930

Published: 2018

Journal Articles

NOX2 Derived Superoxide Induces Pro-Tumoral p16INK4a Driven Senescence in the AML Bone Marrow Microenvironment

Charlotte Hellmich, MBBChir, BSc, MRCP, Amina Abdul-Aziz, MSc, Yu Sun, BSc, MSc, Christopher Richard Marlein, BSc, Eoghan Forde, Rachel E Piddock, BSc, Manar Shafat, MSc, Adam Morfakis, BSc, Mehta Tarang, Federica Di Palma, Christopher Ingham, Angela Collins, MBBS, Anna Haestier, Bsc, PgD MBBS, MRCOG, Judith Campisi, PhD, Kristian Bowles, MBBS, PhD, Stuart Rushworth, PhD BSc

Blood (2018) 132 (Supplement 1): 2770.

https://doi.org/10.1182/blood-2018-99-115274

Published: 2018

Journal Articles

All-Trans Retinoic Acid (ATRA) up-Regulates Cell Surface CD38 Expression Which Promotes Pro-Tumoral Mitochondrial Trafficking from Stromal Cells to Multiple Myeloma

Christopher Richard Marlein, BSc, Rebecca H Horton, Rachel E Piddock, BSc, Jayna J Mistry, BSc, Charlotte Hellmich, MBBChir, BSc, MRCP, Cesar A. Gomez, MD PhD FRCPath, Kristian Bowles, MBBS, PhD, Stuart Rushworth, PhD BSc

Blood (2018) 132 (Supplement 1): 3153.

https://doi.org/10.1182/blood-2018-99-110323

Published: 2018

Journal Articles

PGC1α Driven Mitochondrial Biogenesis within the Bone Marrow Stromal Cells of the Acute Myeloid Leukemia Micro-Environment Is a Pre-Requisite for Mitochondrial Transfer to Leukemic Blasts

Christopher Marlein, BSc, Lyubov Zaitseva, PhD BSc, Rachel Piddock, BSc, Manar Shafat, MSc, Angela Collins, MBBS, Kristian Bowles, MBBS, PhD, Stuart Rushworth, PhD BSc

Blood (2017) 130 (Supplement 1): 3927.

https://doi.org/10.1182/blood.V130.Suppl_1.3927.3927

Published: 2017

Journal Articles

Mitochondria Are Transferred from Non-Malignant Stroma Cells to Malignant Plasma Cells, Via Tunnelling Nanotubules in a CD38 Dependent Mechanism, a Process That Promotes Myeloma Proliferation

Christopher Marlein, BSc, Rachel Piddock, BSc, Lyubov Zaitseva, PhD BSc, Martin Auger, MBBS, Kristian Bowles, MBBS, PhD, Stuart Rushworth, PhD BSc

Blood (2017) 130 (Supplement 1): 589.

https://doi.org/10.1182/blood.V130.Suppl_1.589.589

Published: 2017

Journal Articles

Acute Myeloid Leukaemia Induces p16 Driven Senescence in the Bone Marrow Microenvironment to Support Their Proliferation and Survival

Amina Abdul-Aziz, MSc, Manar Shafat, MSc, Rachel Piddock, BSc, Christopher Marlein, BSc, Judith Campisi, PhD, Kristian Bowles, MBBS, PhD, Stuart Rushworth, PhD BSc

Blood (2017) 130 (Supplement 1): 1394.

https://doi.org/10.1182/blood.V130.Suppl_1.1394.1394

Published: 2017

NARROW

Extended Intensified Consolidation and Maintenance Improve Ultra High-Risk Multiple Myeloma Patient Outcome - Long-Term Follow-up of the Ukmra Optimum/Muknine Trial

Age-Associated Macrophage Polarization to an M2 Phenotype Drives Myeloma Proliferation in the Aged Bone Marrow By Loss of Tumor-Associated Phagocytosis

Repolarisation of M2 Macrophages Via Cgas-Sting Activation Enhances Phagocytosis of Acute Myeloid Leukaemia

Efficacy and Tolerability of Trametinib in Adults with Histiocytic Neoplasms

PAI-1 Mediates the Switch in Free Fatty Acid Metabolism from the Liver to the Bone Marrow to Support Hematopoietic Stem and Progenitor Cell Expansion during the Initial Stages of Infection

A Prospective Analysis of Outcomes Following Successive Lines of Treatment in Mantle Cell Lymphoma in an Unselected Previously Untreated Population: The UK MCL Biobank

Acute Myeloid Leukemia Induces an Increased Senescent Phenotype in the Large Intestine Which Protects Barrier Function and Reduces Leakiness

Sting Activation in Bone Marrow Macrophages Targets AML Blasts for Phagocytosis in an ICAM-1 Dependent Mechanism

Sphingomyelinase Regulates the Release of Protumoral Mitochondria Containing-Vesicles from AML Cells

The Aging Bone Marrow Niche Disrupts Glutamine Metabolism By Upregulating HSC Derived Glutamine Synthetase

AML Inhibits Lipid Uptake By the Liver through an HGF/c-MET Dependent Mechanism Which Results in an Increased Supply of Free Fatty Acid to the Tumor

Acute Myeloid Leukemia Driven IL-3 Dependent Upregulation of BCL-2 in Non-Malignant Hematopoietic Progenitor Cells Increases Venetoclax Induced Cytopenias

IL-6 Mediates a Switch in Free Fatty Acid Metabolism from the Liver to the Bone Marrow to Support HSC Expansion during Infection

Multiple Myeloma Induced IL-6 Reprograms Lipid Metabolism through a CD36 Dependent Mechanism

Stressed Hematopoiesis Induces Mitochondrial Trafficking to Hematopoietic Stem Cells

NOX2 Derived Superoxide Induces Pro-Tumoral p16INK4a Driven Senescence in the AML Bone Marrow Microenvironment

All-Trans Retinoic Acid (ATRA) up-Regulates Cell Surface CD38 Expression Which Promotes Pro-Tumoral Mitochondrial Trafficking from Stromal Cells to Multiple Myeloma

PGC1α Driven Mitochondrial Biogenesis within the Bone Marrow Stromal Cells of the Acute Myeloid Leukemia Micro-Environment Is a Pre-Requisite for Mitochondrial Transfer to Leukemic Blasts

Mitochondria Are Transferred from Non-Malignant Stroma Cells to Malignant Plasma Cells, Via Tunnelling Nanotubules in a CD38 Dependent Mechanism, a Process That Promotes Myeloma Proliferation

Acute Myeloid Leukaemia Induces p16 Driven Senescence in the Bone Marrow Microenvironment to Support Their Proliferation and Survival

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only