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Dominic Fowler-Shorten
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Journal Articles

The Aging Bone Marrow Niche Disrupts Glutamine Metabolism By Upregulating HSC Derived Glutamine Synthetase

Charlotte Hellmich, Edyta E Wojtowicz, Dominic Fowler-Shorten, Rebecca S Maynard, Katherine Hampton, Iain Macaulay, Kristian Bowles, Stuart Rushworth
Journal: Blood
Blood (2023) 142 (Supplement 1): 1304.
https://doi.org/10.1182/blood-2023-180194
Published: 2023
Journal Articles

Multiple Myeloma Induced IL-6 Reprograms Lipid Metabolism through a CD36 Dependent Mechanism

Martha Ehikioya, Annalisa Altera, Katherine Hampton, Rebecca S Maynard, Dominic Fowler-Shorten, Charlotte Hellmich, Kristian Bowles, Matthew Markham, Ravindu De Silva, Stuart Rushworth
Journal: Blood
Blood (2023) 142 (Supplement 1): 6566.
https://doi.org/10.1182/blood-2023-177900
Published: 2023
Journal Articles

IL-6 Mediates a Switch in Free Fatty Acid Metabolism from the Liver to the Bone Marrow to Support HSC Expansion during Infection

Katherine Hampton, Jayna Mistry, Rebecca S Maynard, Dominic Fowler-Shorten, Charlotte Hellmich, Naiara Beraza, Kristian Bowles, Stuart Rushworth
Journal: Blood
Blood (2023) 142 (Supplement 1): 1332.
https://doi.org/10.1182/blood-2023-178618
Published: 2023
Journal Articles

Sting Activation in Bone Marrow Macrophages Targets AML Blasts for Phagocytosis in an ICAM-1 Dependent Mechanism

Ravindu De Silva, Matthew Markham, Rebecca S Maynard, Katherine Hampton, Charlotte Hellmich, Dominic Fowler-Shorten, Kristian Bowles, Stuart Rushworth
Journal: Blood
Blood (2023) 142 (Supplement 1): 1597.
https://doi.org/10.1182/blood-2023-185880
Published: 2023
Journal Articles

AML Inhibits Lipid Uptake By the Liver through an HGF/c-MET Dependent Mechanism Which Results in an Increased Supply of Free Fatty Acid to the Tumor

Rebecca S Maynard, Charlotte Hellmich, Katherine Hampton, Dominic Fowler-Shorten, Matthew Markham, Annalisa Altera, Thomas Flint, Ravindu De Silva, Naiara Beraza, Kristian Bowles, Stuart Rushworth
Journal: Blood
Blood (2023) 142 (Supplement 1): 6031.
https://doi.org/10.1182/blood-2023-178574
Published: 2023
Journal Articles

Acute Myeloid Leukemia Driven IL-3 Dependent Upregulation of BCL-2 in Non-Malignant Hematopoietic Progenitor Cells Increases Venetoclax Induced Cytopenias

Dominic Fowler-Shorten, Rebecca S Maynard, Katherine Hampton, Martha Ehikioya, Edyta E Wojtowicz, Kristian Bowles, Stuart Rushworth, Charlotte Hellmich
Journal: Blood
Blood (2023) 142 (Supplement 1): 293.
https://doi.org/10.1182/blood-2023-173835
Published: 2023