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Journal Articles

Chromomycin A2 exhibits antileukemic effects by coordinated disruption of survival pathways

Keli Lima, Emilly Vieira, Rita De Cássia Cavaglieri Medeiros, Frederico Lisboa Nogueira, Leticia Costa-Lotufo, João Agostinho Machado-Neto, Eduardo Rego

Blood (2025) 146 (Supplement 1): 7848.

https://doi.org/10.1182/blood-2025-7848

Published: 2025

Journal Articles

Cholesterol biosynthesis-related genes reveal new opportunities for risk stratification and treatment in Acute Myeloid Leukemia

Maria Luiza Salustiano-Bandeira, Bruna Ormrod, Maria Fernanda Madrid Mendoza, César Alexander Ortiz Rojas, Amanda Aguiar, Diego Pereira-Martins, Juan Coelho-Silva, Jan Jacob Schuringa, Gerwin A. Huls, Antonio Lucena-Araujo, Eduardo Rego

Blood (2025) 146 (Supplement 1): 3505.

https://doi.org/10.1182/blood-2025-3505

Published: 2025

Journal Articles

BPI-2358 reprograms immunosuppressive macrophages and impairs leukemic progression in MN1-overexpressing AML In Vivo

Lucio Pinheiro, Isabel Weinhäuser, Diego Pereira-Martins, Katherine Hampton, Annalisa Altera, Dominic Fowler-Shorten, Matthew Markham, Alyssa Polski-Delve, Tabitha Bartlett, Charlotte Hellmich, Luise Araujo De Albuquerque Simoes, Cleide Lúcia Araujo, Rita De Cássia Cavaglieri Medeiros, Lynn Quek, Gerwin A. Huls, Jan Jacob Schuringa, Stuart Rushworth, Eduardo Rego

Blood (2025) 146 (Supplement 1): 5066.

https://doi.org/10.1182/blood-2025-5066

Published: 2025

Journal Articles

Healthcare inequities in Latin America outweigh the benefits of pediatric regimens in adult acute lymphoblastic leukemia

Blood (2025) 146 (Supplement 1): 288.

https://doi.org/10.1182/blood-2025-288

Published: 2025

Journal Articles

Early flow cytometry-based MRD predicts relapse in intermediate-risk AML from low- and middle-income countries

Blood (2025) 146 (Supplement 1): 1739.

https://doi.org/10.1182/blood-2025-1739

Published: 2025

Journal Articles

Metabolic reprogramming drives acquired venetoclax resistance in Acute Myeloid Leukemia and reveals targetable vulnerabilities

Keli Lima, Gustavo de Queiroz, Marcella Cipelli, Victoria Tomaz, Luiz Gustavo Cortes, Marina Basto Silva, Rafael Guedes, Paulo Campregher, Niels Câmara, Leticia Costa-Lotufo, Eduardo Rego, João Agostinho Machado-Neto

Blood (2025) 146 (Supplement 1): 6785.

https://doi.org/10.1182/blood-2025-6785

Published: 2025

Journal Articles

Comparative efficacy of azacitidine plus venetoclax in patients with de novo and secondary Acute Myeloid Leukemia

Blood (2025) 146 (Supplement 1): 5171.

https://doi.org/10.1182/blood-2025-5171

Published: 2025

Journal Articles

Differentiation of human induced pluripotent stem cells expressing chimeric antigen receptors into distinct immune cells as an off-the-shelf strategy for tumor treatments

Paula Ribeiro, Erika Salles, Luana Catharino, Ana Carolina Ralph, Rafael Almeida, Samuel COUTO, Dara Rúbia Condomitti, Tânia Reis, José Alexandre Barbuto, Eduardo Rego, Theo Gremen Oliveira, Vanderson Rocha, Rodrigo Ramos

Blood (2025) 146 (Supplement 1): 4136.

https://doi.org/10.1182/blood-2025-4136

Published: 2025

Journal Articles

Translational investigation of tolinapant (ASTX660) in Acute Myeloid Leukemia using integrated clinical, bioinformatic, and pharmacological approaches

Keli Lima, Frederico Lisboa Nogueira, Catarina Reis-Silva, Rita De Cássia Cavaglieri Medeiros, Leticia Costa-Lotufo, João Agostinho Machado-Neto, Eduardo Rego

Blood (2025) 146 (Supplement 1): 2552.

https://doi.org/10.1182/blood-2025-2552

Published: 2025

Journal Articles

The 10-minute targeted geriatric assessment (10-TaGA), a 10-domain-to-one-score tool, predicts early death in intensively treated older AML patients: First results from a multicenter study

Frederico Lisboa Nogueira, Olga Laura Sena Almeida, Maria Aparecida Camargos Bicalho, Fernanda Rodrigues Mendes, Ana Beatriz Firmato Gloria, Paula Cardoso Bastos Marun, Sandra Guerra Xavier, Evandro Maranhão Fagundes, Eduardo Ferriolli, Eduardo Rego

Blood (2025) 146 (Supplement 1): 1600.

https://doi.org/10.1182/blood-2025-1600

Published: 2025

Journal Articles

Filamin-a expression in Acute Myeloid Leukemia: A multi-omic analysis of prognostic, metabolic and therapeutic implications.

Josana de Moraes Coelho Cabral, João Agostinho Machado-Neto, César Alexander Ortiz Rojas, Eduardo Rego

Blood (2025) 146 (Supplement 1): 6756.

https://doi.org/10.1182/blood-2025-6756

Published: 2025

Journal Articles

FLT3-ITD mutation promotes leukemic differentiation toward an immature cytotoxic stage

Blood (2025) 146 (Supplement 1): 1703.

https://doi.org/10.1182/blood-2025-1703

Published: 2025

Journal Articles

Social determinants outweigh geographic barriers in Acute Myeloid Leukemia survival: Insights from a brazilian multicenter study

Luiza Perruso, Abel Costa, Wellington Silva, Rafaela Nalesso, Verena Pfister, Maria Daniela Colombo, Flávia Xavier, Renata Baptista, Fábio Pires, Ederson Mattos, Eduardo Rego

Blood (2025) 146 (Supplement 1): 965.

https://doi.org/10.1182/blood-2025-965

Published: 2025

Journal Articles

Independent, International Validation and Refinement of a Machine Learning Algorithm to Classify Acute Leukemia Using Routine Laboratory Features

Amin T. Turki, Alberto Hernández Sánchez, Wellington Silva, Magdalena Karasek, Luca Guarnera, Koray Yalçin, Amir Enshaei, Marta Sobas, Dirk Reinhardt, Maria M Rivas, Deepak Kumar Mishra, Eduardo Rego, Ahmet Koc, Paola Núñez Medina, Maria Teresa Voso, Anthony Moorman, Felix Nensa, Merlin Engelke

Blood (2024) 144 (Supplement 1): 790.

https://doi.org/10.1182/blood-2024-207058

Published: 2024

Journal Articles

Management of acute promyelocytic leukemia: updated recommendations from an expert panel of the European LeukemiaNet

Blood (2019) 133 (15): 1630–1643.

https://doi.org/10.1182/blood-2019-01-894980

Published: 2019

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Chromomycin A2 exhibits antileukemic effects by coordinated disruption of survival pathways

Cholesterol biosynthesis-related genes reveal new opportunities for risk stratification and treatment in Acute Myeloid Leukemia

BPI-2358 reprograms immunosuppressive macrophages and impairs leukemic progression in MN1-overexpressing AML In Vivo

Healthcare inequities in Latin America outweigh the benefits of pediatric regimens in adult acute lymphoblastic leukemia

Early flow cytometry-based MRD predicts relapse in intermediate-risk AML from low- and middle-income countries

Metabolic reprogramming drives acquired venetoclax resistance in Acute Myeloid Leukemia and reveals targetable vulnerabilities

Comparative efficacy of azacitidine plus venetoclax in patients with de novo and secondary Acute Myeloid Leukemia

Differentiation of human induced pluripotent stem cells expressing chimeric antigen receptors into distinct immune cells as an off-the-shelf strategy for tumor treatments

Translational investigation of tolinapant (ASTX660) in Acute Myeloid Leukemia using integrated clinical, bioinformatic, and pharmacological approaches

The 10-minute targeted geriatric assessment (10-TaGA), a 10-domain-to-one-score tool, predicts early death in intensively treated older AML patients: First results from a multicenter study

Filamin-a expression in Acute Myeloid Leukemia: A multi-omic analysis of prognostic, metabolic and therapeutic implications.

FLT3-ITD mutation promotes leukemic differentiation toward an immature cytotoxic stage

Social determinants outweigh geographic barriers in Acute Myeloid Leukemia survival: Insights from a brazilian multicenter study

Independent, International Validation and Refinement of a Machine Learning Algorithm to Classify Acute Leukemia Using Routine Laboratory Features

Management of acute promyelocytic leukemia: updated recommendations from an expert panel of the European LeukemiaNet

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American Society of Hematology

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