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Journal Articles

Rapid clonal selection within early hematopoietic cell compartments presages outcome to ivosidenib combination therapy

Available to Purchase
Sven Turkalj, Felix A. Radtke, Bilyana Stoilova, Rabea Mecklenbrauck, Angus J. Groom, Niels Asger Jakobsen, Curtis A. Lachowiez, Marlen Metzner, Batchimeg Usukhbayar, Mirian Angulo Salazar, Zhihong Zeng, Sanam Loghavi, Jennifer Marvin-Peek, Verena Körber, Farhad Ravandi, Ghayas C. Issa, Tapan M. Kadia, Vasiliki Symeonidou, Anne P. de Groot, Hagop M Kantarjian, Koichi Takahashi, Marina Konopleva, Courtney D. DiNardo, Paresh Vyas
Journal: Blood
Blood blood.2024027948.
https://doi.org/10.1182/blood.2024027948
Published: 2025
Includes: Supplemental data
Journal Articles

BLAST: a globally applicable and molecularly versatile survival model for chronic myelomonocytic leukemia

Available to Purchase
Ayalew Tefferi, Saubia Fathima, Maymona Abdelmagid, Ali Khalid A. Alsugair, Fnu Aperna, Mahsa Rezasoltani, Muhammad Yousuf, Anuya Natu, Clifford M. Csizmar, Mark Gurney, Terra L. Lasho, Christy M. Finke, Rashmi Kangal-Shamanna, Danielle Hammond, Kelly Chien, Alexandre Bazinet, Courtney D. DiNardo, Tapan M. Kadia, Abhishek A. Mangaonkar, Naval Daver, Animesh Pardanani, Gautam Borthakur, Cinthya Zepeda-Mendoza, Kaaren K. Reichard, Rong He, Sanam Loghavi, Francesco Passamonti, Farhad Ravandi, Koji Sasaki, Dirk R. Larson, Guillermo Garcia-Manero, Francesco Onida, Naseema Gangat, Guillermo Montalban-Bravo, Mrinal M. Patnaik
Journal: Blood
Blood (2025) 146 (7): 874–886.
https://doi.org/10.1182/blood.2024027170
Published: 2025
Includes: Supplemental data
Journal Articles

Blood-based proteomic profiling identifies OSMR as a novel biomarker of AML outcomes

Open Access
Patrick K. Reville, Bofei Wang, Jennifer Marvin-Peek, Bin Yuan, Yu-An Kuo, Araceli Garza, Jessica Root, Wei Qiao, Andrea Arruda, Ivo Veletic, Yiwei Liu, Nicholas J. Short, Courtney D. DiNardo, Tapan M. Kadia, Naval G. Daver, Philip L. Lorenzi, Koji Sasaki, Steven Kornblau, Mark D. Minden, Farhad Ravandi, Hagop M. Kantarjian, Hussein A. Abbas
Journal: Blood
Blood (2025) 145 (25): 3015–3029.
https://doi.org/10.1182/blood.2024027244
Published: 2025
Includes: Supplemental data
Journal Articles

Outcomes of Adult Patients with Newly Diagnosed IDH-Mutated Acute Myeloid Leukemia Receiving Intensive Chemotherapy Plus Venetoclax

Free
Jennifer Croden, Jennifer Marvin-Peek, Marina Konopleva, Gautam Borthakur, Naval Daver, Hussein A. Abbas, Koichi Takahashi, Koji Sasaki, Guillermo Garcia-Manero, Nitin Jain, Naveen Pemmaraju, Nicholas J. Short, Danielle Hammond, Elias Jabbour, Lucia Masarova, Kelly S. Chien, Ghayas C. Issa, Guillermo Montalban-Bravo, Musa Yilmaz, Abhishek Maiti, Yesid Alvarado Valero, Steven M. Kornblau, Farhad Ravandi, Hagop Kantarjian, Tapan M. Kadia, Courtney D. DiNardo
Journal: Blood
Blood (2024) 144 (Supplement 1): 6126.
https://doi.org/10.1182/blood-2024-207413
Published: 2024
Journal Articles

A Phase I/II Study of Mini-Hyper-CVD, Venetoclax and Navitoclax in Patients with Relapsed/Refractory Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia

Free
Nicholas J. Short, Hagop Kantarjian, Nitin Jain, Jayastu Senapati, Fadi G. Haddad, Omer Karrar, Kelly S. Chien, Eitan Kugler, Adaeze Elechi, Regina Abramova, Min Zhao, Rebecca Garris, Marina Konopleva, Farhad Ravandi, Elias Jabbour
Journal: Blood
Blood (2024) 144 (Supplement 1): 4198.
https://doi.org/10.1182/blood-2024-206487
Published: 2024
Journal Articles

Phase II Study of Inotuzumab Ozogamicin for the Treatment of Measurable Residual Disease-Positive B-Cell Acute Lymphoblastic Leukemia: 3-Year Update

Free
Fadi G. Haddad, Hagop M. Kantarjian, Nicholas J. Short, Jayastu Senapati, Nitin Jain, Koji Sasaki, Jeffrey L. Jorgensen, Joseph E. Jabbour, Sa A. Wang, Yesid Alvarado Valero, Xuemei Wang, Alessandra Ferrajoli, Diane Habib, Jan A. Burger, Courtney D. DiNardo, Zena Komrokji, Lucia Masarova, Tapan M. Kadia, Guillermo Garcia-Manero, Farhad Ravandi, Rebecca Garris, Elias Jabbour
Journal: Blood
Blood (2024) 144 (Supplement 1): 4194.
https://doi.org/10.1182/blood-2024-210642
Published: 2024
Journal Articles

A Phase I Study of Nivolumab in Combination with Ipilimumab for the Treatment of Patients with High Risk or Refractory/Relapsed Acute Myeloid Leukemia Following Allogeneic Stem Cell Transplantation

Free
Gheath Alatrash, Cristina Knape, Laura Whited, Dawen Sui, Cara L Haymaker, Jason Yeh, Megan Marcotulli, Pariya Sukhumalchandra, Lisa St. John, Hsinyi Lu, Daniela E. Duenas, Ignacio Wistuba, Julia Mendoza Perez, Beatriz Sanchez Espiridion, Roland L. Bassett, Tapan M. Kadia, Courtney D. DiNardo, Farhad Ravandi, Jeremy Ramdial, Rohtesh S. Mehta, Amin M. Alousi, Betul Oran, Issa F. Khouri, Qaiser Bashir, Chitra Hosing, Muzaffar H. Qazilbash, Jin S. Im, Partow Kebriaei, Pavan Bachireddy, Jeffrey J. Molldrem, Jeffrey L. Jorgensen, Sa A. Wang, Wei WANG, Uday Popat, Elizabeth J. Shpall, Richard E. Champlin, Hagop M. Kantarjian, Naval Daver
Journal: Blood
Blood (2024) 144 (Supplement 1): 1047.
https://doi.org/10.1182/blood-2024-211343
Published: 2024
Journal Articles

Phase 1b/2 Study of Decitabine and Venetoclax in Combination with the Targeted Mutant IDH1 Inhibitor Olutasidenib for Patients with Relapsed/Refractory AML, High Risk MDS, or Newly Diagnosed AML Not Eligible for Chemotherapy with an IDH1 Mutation

Free
Courtney D. DiNardo, Kelly S. Chien, Jillian Mullin, Danielle Hammond, Jeremy Ramdial, Tapan M. Kadia, Fadi G. Haddad, Musa Yilmaz, Koji Sasaki, Ghayas C. Issa, Koichi Takahashi, Elizabeth J. Shpall, Farhad Ravandi, Naval Daver, Hagop Kantarjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 1527.2.
https://doi.org/10.1182/blood-2024-208771
Published: 2024
Journal Articles

A Phase I/II Study of Gilteritinib and Momelotinib for Patients with Relapsed/Refractory FLT3 -Mutated Acute Myeloid Leukemia: A Trial in Progress

Free
Nicholas J. Short, Farhad Ravandi, Naval Daver, Courtney D. DiNardo, Gautam Borthakur, Tapan M. Kadia, Musa Yilmaz, Ghayas C. Issa, Regina Abramova, Araceli Isabella Garza, Hagop M. Kantarjian, Hussein A. Abbas
Journal: Blood
Blood (2024) 144 (Supplement 1): 4288.1.
https://doi.org/10.1182/blood-2024-200923
Published: 2024
Journal Articles

Outcomes of Patients with IDH1 -Mutated Myeloid Neoplasms Treated with Olutasidenib

Free
Kelly S. Chien, Koji Sasaki, Deborah McCue, Naval Daver, Tapan M. Kadia, Nicholas J. Short, Ghayas C. Issa, Guillermo Montalban-Bravo, Fadi G. Haddad, Danielle Hammond, Mahesh Swaminathan, Alexandre Bazinet, Farhad Ravandi, Guillermo Garcia-Manero, Sherry Pierce, Hagop M. Kantarjian, Courtney D. DiNardo
Journal: Blood
Blood (2024) 144 (Supplement 1): 6042.
https://doi.org/10.1182/blood-2024-208611
Published: 2024
Journal Articles

Clinical Outcomes of Patients with AML Receiving Lower Intensity Chemotherapy with or without the Use of Granulocyte-Colony Stimulating Factor (GCSF)

Free
Hannah Goulart, Alexandre Bazinet, Caitlin R Rausch, Koji Sasaki, Courtney D. DiNardo, Naval Daver, Alex Bataller, Naveen Pemmaraju, Nicholas J. Short, Jayastu Senapati, Ghayas C. Issa, Elias Jabbour, Guillermo Garcia-Manero, Farhad Ravandi, Hagop M. Kantarjian, Tapan M. Kadia
Journal: Blood
Blood (2024) 144 (Supplement 1): 5968.
https://doi.org/10.1182/blood-2024-202643
Published: 2024
Journal Articles

A Phase 1/1b Open-Label, Dose Escalation, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-Leukemic Activity of the Orally Available CDC-like Kinase Inhibitor, BH-30236, in Adults with R/R AML or HR-MDS

Free
Eytan M. Stein, Leora Boussi, Alice Mims, Justin M. Watts, Gabriel N Mannis, Hongtao Liu, David Sallman, Farhad Ravandi, Gary J. Schiller, Eunice S. Wang, Brian J. Ball, J. Jean Cui, Jihao Zhou, Armin Graber, Zachary Zimmerman, Stephen Anthony Strickland
Journal: Blood
Blood (2024) 144 (Supplement 1): 5998.
https://doi.org/10.1182/blood-2024-204046
Published: 2024
Journal Articles

Phase 1 Study of AXL/MER/CSF1R Inhibitor Q702 with Azacitidine and Venetoclax for Relapsed or Refractory Acute Myeloid Leukemia

Free
Abhishek Maiti, Sean M. Post, Courtney D. DiNardo, Naval Daver, Tapan M. Kadia, Allison Pike, Hyunsoo Hwang, Xuelin Huang, Michael Andreeff, Farhad Ravandi, Jinho CHOI, Hyunji Ahn, Jeongjun Kim, Kiyean Nam, Gautam Borthakur
Journal: Blood
Blood (2024) 144 (Supplement 1): 5994.
https://doi.org/10.1182/blood-2024-202834
Published: 2024
Journal Articles

Comprehensive Characteristics and Outcomes of Myeloid Neoplasms Following Chimeric Antigen Receptor T-Cell Therapy for Other Hematologic Malignancies

Free
Danielle Hammond, Koji Sasaki, Koichi Takahashi, Elizabeth J. Shpall, Uday Popat, Betul Oran, Gheath Al-Atrash, Krina K. Patel, Jason R. Westin, Sattva S. Neelapu, Yesid Alvarado-Valero, Kelly S. Chien, Naval Daver, Guillermo Montalban-Bravo, Abhishek Maiti, Musa Yilmaz, Elias Jabbour, Naveen Pemmaraju, Mahesh Swaminathan, Jo Ishizawa, Nitin Jain, Alessandra Ferrajoli, Farhad Ravandi, Steven M. Kornblau, Gautam Borthakur, Guillermo Garcia-Manero, Hagop M. Kantarjian, Patrick K. Reville, Hussein A. Abbas
Journal: Blood
Blood (2024) 144 (Supplement 1): 1837.
https://doi.org/10.1182/blood-2024-206801
Published: 2024
Journal Articles

Impact of Flow Cytometry-Based Measurable Residual Disease Clearance Kinetics in Patients with Acute Myeloid Leukemia Undergoing Intensive Chemotherapy

Free
Wei-Ying Jen, Koji Sasaki, Farhad Ravandi, Tapan M. Kadia, Sa A. Wang, Wei Wang, Sanam Loghavi, Naval Daver, Courtney D. DiNardo, Ghayas C. Issa, Hussein A. Abbas, Cedric Nasnas, Alex Bataller, Samuel Urrutia, Sherry Pierce, Hagop M. Kantarjian, Nicholas J. Short
Journal: Blood
Blood (2024) 144 (Supplement 1): 1572.
https://doi.org/10.1182/blood-2024-212036
Published: 2024
Journal Articles

Impact of Post-Remission Intensive (IC) Consolidation Chemotherapy Cycles on Overall and Relapse Free Survival after Allogeneic Stem Cell Transplant (SCT) in Patients with Acute Myeloid Leukemia (AML) Receiving IC + Venetoclax

Free
Jennifer Marvin-Peek, Hagop M. Kantarjian, Wei-Ying Jen, Gautam Borthakur, Naval Daver, Abhishek Maiti, Nicholas J. Short, Steven M. Kornblau, Naveen Pemmaraju, Eitan Kugler, Alexandre Bazinet, Yesid Alvarado-Valero, Hussein A. Abbas, Guillermo Garcia-Manero, Uday Popat, Elizabeth J. Shpall, Farhad Ravandi, Courtney D. DiNardo, Tapan M. Kadia
Journal: Blood
Blood (2024) 144 (Supplement 1): 3572.
https://doi.org/10.1182/blood-2024-202414
Published: 2024
Journal Articles

A Multi-Site Break through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenib (Trial In Progress)

Free
Ghayas C. Issa, Alexander J. Ambinder, Wenbin Xiao, Scott Manalis, Alex K Shalek, Lukasz P. Gondek, Alex Kentsis, Nicholas J. Short, Naval Daver, Jing Ning, Lianchun Xiao, Michael Hemann, Ken Chen, Keyur P. Patel, Pavan Bachireddy, Andrew A. Lane, Marina Konopleva, Omar Abdel-Wahab, Jeffrey J. Molldrem, Ross L Levine, Mark J. Levis, Richard M Stone, Michael Andreeff, Farhad Ravandi, Aaron D. Goldberg, Jacqueline S. Garcia
Journal: Blood
Blood (2024) 144 (Supplement 1): 4265.2.
https://doi.org/10.1182/blood-2024-201582
Published: 2024
Journal Articles

A Phase 1 Study Investigating the Safety and Efficacy of Danvatirsen As Monotherapy Followed By Combination with Venetoclax in Patients with Relapsed/Refractory MDS and AML

Free
Aditi Shastri, Mendel Goldfinger, Ioannis Mantzaris, Guillermo Garcia-Manero, Tapan M. Kadia, Jing Ning, Balda Tirone, Rikin Gandhi, Farhad Ravandi, Naveen Pemmaraju, Guillermo Montalban-Bravo, Annemarie Munoz, Michelle Golez, Lianchun Xiao, Kith Pradhan, Karen Fehn, Lamisha Shah, Hui Zhang, Samarpana Chakraborty, Eric J. Feldman, Nicholas J. Short, Jayastu Senapati, Dennis L Cooper, Alejandro Sica, Noah Kornblum, Lauren Shapiro, Nishi Shah, Susan MacIntyre, Ulrich Steidl, Amit Verma, Kira Gritsman, Andrew Denker, Marina Konopleva, Naval Daver
Journal: Blood
Blood (2024) 144 (Supplement 1): 4265.5.
https://doi.org/10.1182/blood-2024-208998
Published: 2024
Journal Articles

Early Obinutuzumab Significantly Increases Bone Marrow Undetectable MRD (10 -4 sensitivity) (uMRD4) Rate When Combined with Acalabrutinib and Venetoclax in a Randomized Phase II Trial for Treatment Naïve CLL

Free
Mahesh Swaminathan, Philip A. Thompson, Jan A. Burger, Musa Yilmaz, Nitin Jain, Tapan M. Kadia, Lucia Masarova, Yesid Alvarado Valero, Prithviraj Bose, Alessandra Ferrajoli, Ghayas C. Issa, Steven M. Kornblau, Farhad Ravandi, Koji Sasaki, Gautam Borthakur, Kelly S. Chien, Courtney D. DiNardo, Danielle Hammond, Elias Jabbour, Guillermo Montalban-Bravo, Naveen Pemmaraju, Nicholas J. Short, Koichi Takahashi, Francesco Paolo Tambaro, Wei Qiao, Naveen Garg, Michael J. Keating, William G. Wierda
Journal: Blood
Blood (2024) 144 (Supplement 1): 1855.
https://doi.org/10.1182/blood-2024-211110
Published: 2024
Journal Articles

Distinct Impact of Platinum Chemotherapies on the Fitness and Genome of Hematopoietic Stem Cells and the Risk of Therapy-Related Myeloid Neoplasms

Free
Jeremy Connors, Linda Zhang, Hidetaka Uryu, Koji Sasaki, Jennifer Padilla, Zongrui Li, Ken Furudate, Tomoyuki Tanaka, Courtney D. DiNardo, Nicholas J. Short, Naval Daver, Gautham Borthakur, Farhad Ravandi, Tapan M. Kadia, Hagop M. Kantarjian, Elias Jabbour, Simona Colla, Branko Cuglievan, Andrew Futreal, Adam S. Sperling, Guillermo Garcia-Manero, Margaret Goodell, Koichi Takahashi
Journal: Blood
Blood (2024) 144 (Supplement 1): 1816.
https://doi.org/10.1182/blood-2024-212052
Published: 2024