Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 72

Sort by

Sort Order Select

Journal Articles

Prevalence, clinical correlates and clonal inferences of concurrent splicing factor mutations in patients with myeloid neoplasms

Nickolas Steinauer, Vihan Singh, Terra Lasho, Christy Finke, Alejandro Ferrer, Pankaj Pradeep, Jenna Fernandez, Clifford Csizmar, Aref Al-Kali, David Viswanatha, Rong He, Abhishek Mangaonkar, Xi Zhang, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 5650.

https://doi.org/10.1182/blood-2025-5650

Published: 2025

Journal Articles

Consideration of genomic determinants improves the diagnostic accuracy of oligomonocytic chronic myelomonocytic leukemia

Blood (2025) 146 (Supplement 1): 3849.

https://doi.org/10.1182/blood-2025-3849

Published: 2025

Journal Articles

Spatial multiomics reveal a critical role for TIM4-expressing macrophages in blast transformation of chronic myelomonocytic leukemia

Abhishek Mangaonkar, Justin Boysen, Terra Lasho, Christy Finke, Jenna Fernandez, Jose Villasboas Bisneto, Mehrdad Hefazi Torghabeh, Pankaj Pradeep, Will Sherman, Christy Trussoni, Tamas Ordog, Maha Rahim, Alejandro Ferrer, Kaaren Reichard, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 3831.

https://doi.org/10.1182/blood-2025-3831

Published: 2025

Journal Articles

Myeloproliferative neoplasm driver mutations (JAK2/CALR/MPL) in chronic myelomonocytic leukemia are associated with an increased risk of blast transformation

Muhammad Yousuf, Saubia Fathima, Priyansh Faldu, Ali Alsugair, Abiola Bolarinwa, Andrew Cannon, Terra Lasho, Abhishek Mangaonkar, Kaaren Reichard, Rong He, Animesh Pardanani, Naseema Gangat, Ayalew Tefferi

Blood (2025) 146 (Supplement 1): 2067.

https://doi.org/10.1182/blood-2025-2067

Published: 2025

Journal Articles

Somatic ASXL1 mutations in chronic myelomonocytic leukemia result in loss of imprinting control and overexpression of DLK1 through deregulation of DNA methylation

Pankaj Pradeep, Jenna Fernandez, Abhishek Mangaonkar, Nickolas Steinauer, Moritz Binder, Huihuang Yan, Christy Finke, Zhifu Sun, Terra Lasho, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 1457.

https://doi.org/10.1182/blood-2025-1457

Published: 2025

Journal Articles

The somatic DDX41 hot spot mutation (p.R525H) causes skewed differentiation into plasmacytoid dendritic cells in human iPSC and leukemia models

Junichiro Kida, Maggie Fricker, Emily Stepanchick, Yael Kusne, Talha Badar, Terra Lasho, Mrinal Patnaik, Timothy Chlon

Blood (2025) 146 (Supplement 1): 678.

https://doi.org/10.1182/blood-2025-678

Published: 2025

Journal Articles

Fetal hemoglobin dysregulation in inherited and acquired bone marrow failure syndromes

Blood (2025) 146 (Supplement 1): 6750.

https://doi.org/10.1182/blood-2025-6750

Published: 2025

Journal Articles

Clone-specific epigenetic regulatory mechanisms in ASXL1-mutant chronic myelomonocytic leukemia

Moritz Binder, Terra Lasho, Jenna Fernandez, Wazim Mohammed Ismail, Amelia Mazzone, Christy Finke, Pankaj Pradeep, Abhishek Mangaonkar, Nickolas Steinauer, Huihuang Yan, Liguo Wang, Alexandre Gaspar-Maia, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 234.

https://doi.org/10.1182/blood-2025-234

Published: 2025

Journal Articles

MC210807: Phase 1 clinical trial assessing the safety and efficacy of onvansertib, a novel, oral, PLK1 inhibitor in Relapsed/Refractory myeloproliferative chronic myelomonocytic leukemia (CMML).

Abhishek Mangaonkar, Kristen McCullough, Susan Geyer, Ashya Burgess, Kimberly Rice, Eric Asmus, Patricia Koenig, Terra Lasho, Christy Finke, Rachel Reither, Ryan Carr, Jenna Fernandez, Antoine Saliba, Aref Al-Kali, Martin Fernandez-Zapico, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 5634.

https://doi.org/10.1182/blood-2025-5634

Published: 2025

Journal Articles

Interplay between mutant DNMT3A and UBA1 worsens survival through altered inflammatory and metabolic pathways

Blood (2025) 146 (Supplement 1): 3191.

https://doi.org/10.1182/blood-2025-3191

Published: 2025

Journal Articles

Upfront therapy with allogeneic hematopoietic stem cell transplantation versus DNA methyltransferase inhibitors in patients with vexas syndrome: A comparative matched cohort efficacy analysis of 39 patients

Blood (2025) 146 (Supplement 1): 981.

https://doi.org/10.1182/blood-2025-981

Published: 2025

Journal Articles

Unique NK-like T cell population identified in UBA1mt cells in vexas associated with IL-8 mediated activity and cytotoxic response pathways

Terra Lasho, Jenna Fernandez, Pankaj Pradeep, Christy Finke, Abhishek Mangaonkar, Nickolas Steinauer, Bhavisha Patel, Neal Young, David Beck, Kenneth Warrington, Matthew J Koster, Yael Kusne, Fernanda Guitterez-Rodrigues, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 1428.

https://doi.org/10.1182/blood-2025-1428

Published: 2025

Journal Articles

Phenotypic landscape and clinical outcomes associated with promotor TERT mutations in patients with telomere biology disorders

Madeline Franke, Terra Lasho, Abhishek Mangaonkar, Christy Finke, Yael Kusne, Rachel Reither, Alejandro Ferrer, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 4995.

https://doi.org/10.1182/blood-2025-4995

Published: 2025

Journal Articles

The somatic hotspot mutation of DDX41 (p.R525H) elicits dominant-negative effects upon non-truncating germline variants, explaining similar disease risk as truncating variants.

Julianna Fisher, Emily Stepanchick, Andrew Wilson, Junichiro Kida, Talha Badar, Terra Lasho, Yael Kusne, Mrinal Patnaik, Timothy Chlon

Blood (2025) 146 (Supplement 1): 3221.

https://doi.org/10.1182/blood-2025-3221

Published: 2025

Journal Articles

Rapid hematologic germline testing using hair follicle-derived DNA for germline predisposition and inherited marrow failure states

Emma St. Martin, Abhishek Mangaonkar, Ann Moyer, Juliana Perez Botero, Alejandro Ferrer, Ross Rowsey, Benjamin Kipp, Dong Chen, Talha Badar, Jenna Fernandez, Yael Kusne, Christy Finke, Jodi Rindflesch, Terra Lasho, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 3211.

https://doi.org/10.1182/blood-2025-3211

Published: 2025

Journal Articles

Clinical and biological correlates of blast-transformed chronic myelomonocytic leukemia (CMML): A multicenter study of 493 paired cases at chronic phase and at blast transformation

Blood (2025) 146 (Supplement 1): 2081.

https://doi.org/10.1182/blood-2025-2081

Published: 2025

Journal Articles

LS1781 (Arm E): Phase II clinical trial to assess the safety and efficacy of high dose IV ascorbic acid with decitabine in newly diagnosed TET2 mutant chronic myelomonocytic leukemia (CMML)

Abhishek Mangaonkar, Jenna Fernandez, Ashya Burgess, Kristen McCullough, Christy Finke, Terra Lasho, Michelle Amundson, Antoine Saliba, Aasiya Matin, Aref Al-Kali, Hassan Alkhateeb, Mithun Shah, Betsy Knopf, Thomas Witzig, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 2079.

https://doi.org/10.1182/blood-2025-2079

Published: 2025

Journal Articles

Decoding DDX41: Clinical impact of germline and somatic mutations in 77 high-risk myeloid neoplasm patients

Talha Badar, Mahesh Kumar, Yael Kusne, Terra Lasho, James Foran, Hemant Murthy, Mohamed Kharfan-Dabaja, Timothy Chlon, Naseema Gangat, Hassan Alkhateeb, Abhishek Mangaonkar, Rong He, David Viswanatha, Jennifer Jiang, Yao-Shan Fan, Alejandro Ferrer, Mark Litzow, Aref Al-Kali, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 1442.

https://doi.org/10.1182/blood-2025-1442

Published: 2025

Journal Articles

High-dose IV ascorbic acid therapy for patients with CCUS with TET2 mutations

Zhuoer Xie, Jenna Fernandez, Terra Lasho, Christy Finke, Michelle Amundson, Kristen B. McCullough, Betsy R. LaPlant, Abhishek A. Mangaonkar, Naseema Gangat, Kaaren K. Reichard, Michelle Elliott, Thomas E. Witzig, Mrinal M. Patnaik

Blood (2024) 144 (23): 2456–2461.

https://doi.org/10.1182/blood.2024024962

Published: 2024

Includes: Supplemental data

Journal Articles

Venous and arterial thrombosis in patients with VEXAS syndrome

Blood (2024) 143 (21): 2190–2200.

https://doi.org/10.1182/blood.2023022329

Published: 2024

Includes: Supplemental data

Update search

NARROW

Publications

Format

Subjects

Article Type

Topics

Date

Availability

Prevalence, clinical correlates and clonal inferences of concurrent splicing factor mutations in patients with myeloid neoplasms

Consideration of genomic determinants improves the diagnostic accuracy of oligomonocytic chronic myelomonocytic leukemia

Spatial multiomics reveal a critical role for TIM4-expressing macrophages in blast transformation of chronic myelomonocytic leukemia

Myeloproliferative neoplasm driver mutations (JAK2/CALR/MPL) in chronic myelomonocytic leukemia are associated with an increased risk of blast transformation

Somatic ASXL1 mutations in chronic myelomonocytic leukemia result in loss of imprinting control and overexpression of DLK1 through deregulation of DNA methylation

The somatic DDX41 hot spot mutation (p.R525H) causes skewed differentiation into plasmacytoid dendritic cells in human iPSC and leukemia models

Fetal hemoglobin dysregulation in inherited and acquired bone marrow failure syndromes

Clone-specific epigenetic regulatory mechanisms in ASXL1-mutant chronic myelomonocytic leukemia

MC210807: Phase 1 clinical trial assessing the safety and efficacy of onvansertib, a novel, oral, PLK1 inhibitor in Relapsed/Refractory myeloproliferative chronic myelomonocytic leukemia (CMML).

Interplay between mutant DNMT3A and UBA1 worsens survival through altered inflammatory and metabolic pathways

Upfront therapy with allogeneic hematopoietic stem cell transplantation versus DNA methyltransferase inhibitors in patients with vexas syndrome: A comparative matched cohort efficacy analysis of 39 patients

Unique NK-like T cell population identified in UBA1mt cells in vexas associated with IL-8 mediated activity and cytotoxic response pathways

Phenotypic landscape and clinical outcomes associated with promotor TERT mutations in patients with telomere biology disorders

The somatic hotspot mutation of DDX41 (p.R525H) elicits dominant-negative effects upon non-truncating germline variants, explaining similar disease risk as truncating variants.

Rapid hematologic germline testing using hair follicle-derived DNA for germline predisposition and inherited marrow failure states

Clinical and biological correlates of blast-transformed chronic myelomonocytic leukemia (CMML): A multicenter study of 493 paired cases at chronic phase and at blast transformation

LS1781 (Arm E): Phase II clinical trial to assess the safety and efficacy of high dose IV ascorbic acid with decitabine in newly diagnosed TET2 mutant chronic myelomonocytic leukemia (CMML)

Decoding DDX41: Clinical impact of germline and somatic mutations in 77 high-risk myeloid neoplasm patients

High-dose IV ascorbic acid therapy for patients with CCUS with TET2 mutations

Venous and arterial thrombosis in patients with VEXAS syndrome

Email alerts

ASH Publications

American Society of Hematology

Update search

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only