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Journal Articles

Clinicopathologic features of myeloid neoplasms and pre-neoplasms with isolated ZRSR2 mutations

Free
Alma Oskarsdottir, Rong He, Jennifer Jiang, Mahmoud Yacout, Patricia Greipp, Mithun Shah, Hassan Alkhateeb, David Viswanatha, Fiona Craig, Katalin Kelemen, Aref Al-Kali, Dragan Jevremovic
Journal: Blood
Blood (2025) 146 (Supplement 1): 7394.
https://doi.org/10.1182/blood-2025-7394
Published: 2025
Journal Articles

Blast clearance dynamics and time to response across IDH1- and IDH2-mutated AML

Free
Mohamad Sheikh Najeeb, Oudai Alkabbani, Rong He, Dragan Jevremovic, Patricia Greipp, Aasiya Matin, Mehrdad Hefazi Torghabeh, Abhishek Mangaonkar, Mrinal Patnaik, Naseema Gangat, William Hogan, Mark Litzow, Cecilia Arana Yi, James Foran, Mithun Shah, Kebede Begna, Hassan Alkhateeb, Tariq Kewan, Antoine Saliba, Aref Al-Kali
Journal: Blood
Blood (2025) 146 (Supplement 1): 7045.
https://doi.org/10.1182/blood-2025-7045
Published: 2025
Journal Articles

Reduced overall survival in TP53-mutated ccus is driven by prior cytotoxic exposure and cytopenia rather than leukemic progression

Free
Steven Tessier, Yazan Jabban, Hassan Alkhateeb, William Hogan, Mrinal Patnaik, Laura Ongie, Antoine Saliba, Abhishek Mangaonkar, Naseema Gangat, James Foran, Talha Badar, Hemant Murthy, Cecilia Arana Yi, Nathan Punwani, Yael Kusne, Kebede Begna, Ayalew Tefferi, Devendra Hiwase, Aref Al-Kali, Mithun Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 5643.
https://doi.org/10.1182/blood-2025-5643
Published: 2025
Journal Articles

ETNK1 mutations define a distinct subset of myeloid neoplasms with unique cytogenetic and molecular features

Free
Steven Tessier, Najla Al Ali, Michael Trinh, Andrew Brunner, Diletta Fontana, Carlo Gambacorti-Passerini, Rocco Piazza, David Sallman, Eric Padron, Zhuoer Xie, James Foran, Cecilia Arana Yi, Hassan Alkhateeb, Mithun Shah, Rami Komrokji, Aref Al-Kali
Journal: Blood
Blood (2025) 146 (Supplement 1): 3864.
https://doi.org/10.1182/blood-2025-3864
Published: 2025
Journal Articles

17p loss in TP53-non-mutated myeloid neoplasms confers survival comparable to TP53-mutated disease

Free
Gunin Singhal, Franceso Versino, Kevin Hung, Shreyans Gandhi, Henry Wood, Cinthya Mendoza, Emmanuel Gnanamanickam, Frances Aldridge, Naseema Gangat, Dariusz Ladon, Victoria Potter, Beate Betz, Pramila Krishnamurthy, Hosein Anani, Mili Shah, Kar Lok Kong, Torsten Haferlach, Ayalew Tefferi, Ulrich Germing, Mithun Shah, Austin Kulasekararaj, Devendra Hiwase
Journal: Blood
Blood (2025) 146 (Supplement 1): 3858.
https://doi.org/10.1182/blood-2025-3858
Published: 2025
Journal Articles

Insights into clonal and CBC changes at disease evolution among ccus patients

Free
Yazan Jabban, Rong He, Kurt Bessonen, Patricia Greipp, Dragan Jevremovic, David Viswanatha, James Foran, Talha Badar, Cecilia Arana Yi, Yael Kusne, Antoine Saliba, Mehrdad Hefazi Torghabeh, Aasiya Matin, William Hogan, Abhishek Mangaonkar, Mithun Shah, Hassan Alkhateeb, Mrinal Patnaik, Aref Al-Kali
Journal: Blood
Blood (2025) 146 (Supplement 1): 5621.
https://doi.org/10.1182/blood-2025-5621
Published: 2025
Journal Articles

Evolving insights and changes in survival of erdheim-chester disease over time

Free
Mia Poleksic, Grant Spears, Carla Isabel Borre, Dongni Yi, Brinda H Shukla, Jacquelyn Fitzgerald, Muhammad Azeem Khan, Pradeep Bhambhvani, Mitali Sen, Diana Morlote, Aditi Saha, Lucy Bailey, Daniel Sokolowski, William Tobin, Jason Young, Julio Sartori Valinotti, Matthew J Koster, Aldo Acosta Medina, Mithun Shah, N. Nora Bennani, Muhamad Alhaj Moustafa, Talal Hilal, Robert Vassallo, Lucinda Gruber, Surendra Dasari, Karen Rech, Thomas Witzig, Aishwarya Ravindran, Ronald Go, Gaurav Goyal, Jithma Abeykoon
Journal: Blood
Blood (2025) 146 (Supplement 1): 2990.
https://doi.org/10.1182/blood-2025-2990
Published: 2025
Journal Articles

Causes of death in DDX41-mutated myeloid neoplasms: A retrospective study

Free
Nadia Toumeh, Yazan Jabban, Rong He, David Viswanatha, Dragan Jevremovic, Patricia Greipp, James Foran, Talha Badar, Hemant Murthy, Cecilia Arana Yi, Yael Kusne, Antoine Saliba, Mehrdad Hefazi Torghabeh, Aasiya Matin, William Hogan, Kebede Begna, Mithun Shah, Abhishek Mangaonkar, Mrinal Patnaik, Hassan Alkhateeb, Aref Al-Kali
Journal: Blood
Blood (2025) 146 (Supplement 1): 7370.
https://doi.org/10.1182/blood-2025-7370
Published: 2025
Journal Articles

The molecular landscape of patients with malignant histiocytosis

Free
Alanis Rodriguez-Rosario, Jithma Abeykoon, N. Nora Bennani, Karen Rech, Mithun Shah, Aishwarya Ravindran, Aldo Acosta Medina, Gordon Ruan, Dongni Yi, Saurabh Zanwar, Gaurav Goyal, Ronald Go
Journal: Blood
Blood (2025) 146 (Supplement 1): 7335.
https://doi.org/10.1182/blood-2025-7335
Published: 2025
Journal Articles

Fetal hemoglobin dysregulation in inherited and acquired bone marrow failure syndromes

Free
Victoria Heigh, Maymona Abdelmagid, Laura Ongie, Kristen McCullough, Jenna Fernandez, Terra Lasho, Christy Finke, Anand Srinivasan, Mira Kohorst, Asmaa Ferdjallah, William Hogan, Ronald Go, David Dingli, Naseema Gangat, Aref Al-Kali, Kebede Begna, Hassan Alkhateeb, Mithun Shah, Mark Litzow, Mehrdad Hefazi Torghabeh, Aasiya Matin, Kaaren Reichard, Joanna Dalland, Yael Kusne, James Foran, Alejandro Ferrer, Mrinal Patnaik, Abhishek Mangaonkar
Journal: Blood
Blood (2025) 146 (Supplement 1): 6750.
https://doi.org/10.1182/blood-2025-6750
Published: 2025
Journal Articles

Mutational landscape of adult xanthogranuloma

Free
Muhammad Azeem Khan, Karen Rech, Dongni Yi, Carla Isabel Borre, Mia Poleksic, William Tobin, Jason Young, Julio Sartori Valinotti, Matthew J Koster, Aldo Acosta Medina, Mithun Shah, N. Nora Bennani, Muhamad Alhaj Moustafa, Talal Hilal, Robert Vassallo, Lucinda Gruber, Surendra Dasari, Thomas Witzig, Aishwarya Ravindran, Gaurav Goyal, Ronald Go, Jithma Abeykoon
Journal: Blood
Blood (2025) 146 (Supplement 1): 7339.
https://doi.org/10.1182/blood-2025-7339
Published: 2025
Journal Articles

KRAS mutations in histiocytic neoplasms: Mutation spectrum and response to MEK inhibition

Free
Dongni Yi, Carla Isabel Borre, Mia Poleksic, Brinda H Shukla, Jacquelyn Fitzgerald, Muhammad Azeem Khan, Pradeep Bhambhvani, Mitali Sen, Diana Morlote, Aditi Saha, Lucy Bailey, Daniel Sokolowski, Ubenthira Patgunarajah, William Tobin, Jason Young, Julio Sartori Valinotti, Matthew J Koster, Aldo Acosta Medina, Mithun Shah, N. Nora Bennani, Muhamad Alhaj Moustafa, Talal Hilal, Robert Vassallo, Lucinda Gruber, Surendra Dasari, Karen Rech, Thomas Witzig, Aishwarya Ravindran, Gaurav Goyal, Ronald Go, Jithma Abeykoon
Journal: Blood
Blood (2025) 146 (Supplement 1): 6760.
https://doi.org/10.1182/blood-2025-6760
Published: 2025
Journal Articles

Molecular stratification of relapse risk post-allogeneic hematopoietic stem cell transplantation in myeloid neoplasms with non-adverse risk cytogenetics

Free
Khalid Abu-Zeinah, Anmol Baranwal, Khalil Hassan, Al Rabee Kassis, Aasiya Matin, Mehrdad Hefazi Torghabeh, Abhishek Mangaonkar, Mark Litzow, William Hogan, Mithun Shah, David Dingli, Hassan Alkhateeb
Journal: Blood
Blood (2025) 146 (Supplement 1): 6073.
https://doi.org/10.1182/blood-2025-6073
Published: 2025
Journal Articles

The synonymous IDH1 p.Gly105Gly (rs11554137) variant associates with AML post-transplant relapse via aberrant signal transduction pathways

Free
Olisaemeka Ogbue, Emma St. Martin, Oudai Alkabbani, Naseema Gangat, Mithun Shah, Aasiya Matin, Abhishek Mangaonkar, Mehrdad Hefazi Torghabeh, Kebede Begna, Dong Chen, Mark Litzow, Dragan Jevremovic, William Hogan, James Foran, Cecilia Arana Yi, Scott Kaufmann, Mrinal Patnaik, Rong He, Hassan Alkhateeb, Aref Al-Kali, Antoine Saliba
Journal: Blood
Blood (2025) 146 (Supplement 1): 1699.
https://doi.org/10.1182/blood-2025-1699
Published: 2025
Journal Articles

Treatment-specific prognostic performance of ELN 2022, ELN 2024, and beat AML 2024: A real-world AML validation study

Free
Tariq Kewan, Oudai Alkabbani, Rong He, Dragan Jevremovic, Patricia Greipp, Antoine Saliba, Aasiya Matin, Mehrdad Hefazi Torghabeh, Abhishek Mangaonkar, Naseema Gangat, William Hogan, Mrinal Patnaik, Hassan Alkhateeb, Cecilia Arana Yi, James Foran, Mark Litzow, Mithun Shah, Kebede Begna, Aref Al-Kali
Journal: Blood
Blood (2025) 146 (Supplement 1): 996.
https://doi.org/10.1182/blood-2025-996
Published: 2025
Journal Articles

Upfront therapy with allogeneic hematopoietic stem cell transplantation versus DNA methyltransferase inhibitors in patients with vexas syndrome: A comparative matched cohort efficacy analysis of 39 patients

Free
Saubia Fathima, Ali Alsugair, Kimberly Langer, Terra Lasho, Christy Finke, Mark Litzow, Aasiya Matin, Urshila Durani, Mehrdad Hefazi Torghabeh, William Hogan, Mithun Shah, Ronald Go, Gabriel Bartoo, Jade Kutzke, Kristen McCullough, Matthew J Koster, Kenneth Warrington, Kaaren Reichard, Horatiu Olteanu, Yael Kusne, Jeanne Palmer, Saurabh Chhabra, Mary Riwes, Joseph McGuirk, Elizabeth Krakow, Amelia Langston, Taxiarchis Kourelis, David Dingli, Mrinal Patnaik, Hassan Alkhateeb, Abhishek Mangaonkar
Journal: Blood
Blood (2025) 146 (Supplement 1): 981.
https://doi.org/10.1182/blood-2025-981
Published: 2025
Journal Articles

Molecular association with elevated LDH levels in patients with AML

Free
Oudai Alkabbani, Yazan Jabban, Rong He, David Viswanatha, Kurt Bessonen, Patricia Greipp, Dragan Jevremovic, Antoine Saliba, Mehrdad Hefazi Torghabeh, Aasiya Matin, William Hogan, Abhishek Mangaonkar, Hassan Alkhateeb, Mrinal Patnaik, Mithun Shah, Kebede Begna, Aref Al-Kali
Journal: Blood
Blood (2025) 146 (Supplement 1): 7039.
https://doi.org/10.1182/blood-2025-7039
Published: 2025
Journal Articles

Risk-adjusted comparison of survival in chronic myelomonocytic leukemia with and without allogeneic stem cell transplant: Mayo Clinic experience in 775 consecutive patients

Free
Ali Alsugair, Saubia Fathima, Mohammad Alhousani, Estefania Gauto Mariotti, Priyansh Faldu, Muhammad Yousuf, Abiola Bolarinwa, Clifford Csizmar, James Foran, Abhishek Mangaonkar, Mark Litzow, Hemant Murthy, Lisa Sproat, Jeanne Palmer, Aasiya Matin, Ernesto Ayala, James Slack, Luis Porrata, Madiha Iqbal, Nandita Khera, Nathan Punwani, Saad Kenderian, Saurabh Chhabra, Kebede Begna, Animesh Pardanani, William Hogan, Mithun Shah, Hassan Alkhateeb, Naseema Gangat, Mrinal Patnaik, Ayalew Tefferi
Journal: Blood
Blood (2025) 146 (Supplement 1): 5636.
https://doi.org/10.1182/blood-2025-5636
Published: 2025
Journal Articles

Efficacy of frontline fixed duration chemotherapy in MAPK-pathway altered adult langerhans cell histiocytosis: A multi-institutional international retrospective study

Free
Carla Isabel Borre, Mia Poleksic, Grant Spears, Dongni Yi, XI Yang, Haadi Ali, Brinda H Shukla, Jacquelyn Fitzgerald, Muhammad Azeem Khan, Aishwarya Pradeep, Mitali Sen, Diana Morlote, Aditi Saha, Shuko Harada, N. Nora Bennani, Lucy Bailey, Matthew J Koster, Brittany Wade, Robert Vassallo, Aishwarya Ravindran, Muhamad Alhaj Moustafa, Jason Young, Julio Sartori Valinotti, Aldo Acosta Medina, Mithun Shah, William Tobin, Daniel Sokolowski, Lucinda Gruber, Long Chang, Surendra Dasari, Talal Hilal, Karen Rech, Thomas Witzig, Asra Ahmed, Aki Sato, Gaurav Goyal, Ronald Go, Xin-Xin Cao, Jithma Abeykoon
Journal: Blood
Blood (2025) 146 (Supplement 1): 2999.
https://doi.org/10.1182/blood-2025-2999
Published: 2025
Journal Articles

Integrated prognostic model for TP53‑mutated myeloid neoplasms across all myeloid neoplasm subtypes

Free
Devendra Hiwase, Steven Tessier, Kevin Hung, Rong He, Maymona Abdelmagid, Danielle Rud, Michelle Maritz, Aref Al-Kali, Naseema Gangat, Mrinal Patnaik, Abhishek Mangaonkar, Hosein Anani, Antoine Saliba, Nathan Punwani, James Foran, Dong Chen, Emmanuel Gnanamanickam, Hassan Alkhateeb, Dariusz Ladon, Monika Kutyna, Kebede Begna, Hamish Scott, Mehrdad Hefazi Torghabeh, Aasiya Matin, Kaaren Reichard, Cinthya Zepeda, Chris Hahn, William Hogan, Attilio Orazi, Daniel Arber, Chung Hoow Kok, Mithun Shah, Ayalew Tefferi
Journal: Blood
Blood (2025) 146 (Supplement 1): 2087.
https://doi.org/10.1182/blood-2025-2087
Published: 2025