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David Sallman
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Journal Articles

A Phase 1/1b Open-Label, Dose Escalation, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-Leukemic Activity of the Orally Available CDC-like Kinase Inhibitor, BH-30236, in Adults with R/R AML or HR-MDS

Eytan M. Stein, Leora Boussi, Alice Mims, Justin M. Watts, Gabriel N Mannis, Hongtao Liu, David Sallman, Farhad Ravandi, Gary J. Schiller, Eunice S. Wang, Brian J. Ball, J. Jean Cui, Jihao Zhou, Armin Graber, Zachary Zimmerman, Stephen Anthony Strickland
Journal: Blood
Blood (2024) 144 (Supplement 1): 5998.
https://doi.org/10.1182/blood-2024-204046
Published: 2024
Journal Articles

Comparison of Pre-Treatment Sociodemographic and Clinical Characteristics, Symptoms, and Quality of Life Among Older Patients with AML Who Received Intensive Versus Non-Intensive Therapy

Sara M. Tinsley-Vance, Cecile A. Lengacher, Steve K. Sutton, Ram Thapa, Martine Extermann, Daniel Lastorino, Andrew T. Kuykendall, Timothy Kubal, Eric Padron, Onyee Chan, Alison R. Walker, Areej El-Jawahri, David Sallman, Rami S. Komrokji, Jeffrey E Lancet
Journal: Blood
Blood (2024) 144 (Supplement 1): 7915.
https://doi.org/10.1182/blood-2024-211823
Published: 2024
Journal Articles

Reduction in MPN-Total Symptom Score (TSS) Is Associated with Overall Survival (OS) in Chronic Myelomonocytic Leukemia (CMML)

Eric Padron, Wenyi Fan, Sara M. Tinsley-Vance, Amy E. DeZern, Hetty E. Carraway, Marlise R. Luskin, Gail J. Roboz, Onyee Chan, Aaron T. Gerds, Andrew T. Kuykendall, David P. Steensma, Maria Balasis, Jeffrey E Lancet, Qianxing Mo, Mikkael A. Sekeres, David Sallman, Rami S. Komrokji
Journal: Blood
Blood (2024) 144 (Supplement 1): 6750.
https://doi.org/10.1182/blood-2024-211137
Published: 2024
Journal Articles

Characteristics and Survival Outcome of Patients with Isolated 11q Deletion Myelodysplastic Syndromes

Jeannot Kekedjian, Rami S. Komrokji, Najla H. Al Ali, Kensuke Takaoka, David Sallman, Zhuoer Xie, Eric Padron, Kelly S. Chien, Guillermo Montalban-Bravo, Julie Braish, Samuel Urrutia, Alex Bataller, Alexandre Bazinet, Rashmi Kanagal-Shamanna, Guilin Tang, Yue Wei, Hui Yang, Juan Jose Rodriguez Sevilla, Guillermo Garcia-Manero, Koji Sasaki
Journal: Blood
Blood (2024) 144 (Supplement 1): 6746.
https://doi.org/10.1182/blood-2024-208444
Published: 2024
Journal Articles

Myelodysplastic Syndromes with Concomitant SF3B1 Mutation and Deletion of the Long Arm of Chromosome 5 ( SF3B1 del5q ): Outcomes and Response to Treatment

Rami S. Komrokji, Zaker I. Schwabkey, Najla H. Al Ali, Luis E. Aguirre, Maximilian Stahl, Somedeb Ball, Emily F. Mason, Michael R. Savona, Valeria Santini, Angela Consagra, Uwe Platzbecker, Anne Sophie Kubasch, Yazan F Madanat, Pierre Fenaux, Lin-Pierre Zhao, Mikkael A. Sekeres, Namrata S. Chandhok, Matteo Giovanni Della Porta, Luca Lanino, Amy E. DeZern, David Sallman, Zhuoer Xie, Eric Padron, Koji Sasaki, Kensuke Takaoka, Akhil Jain, Mónica Del Rey, Maria Diez-Campelo, Guillermo Garcia-Manero
Journal: Blood
Blood (2024) 144 (Supplement 1): 1845.
https://doi.org/10.1182/blood-2024-207474
Published: 2024
Journal Articles

Efficacy of Luspatercept on Transfusion Burden and Cytopenias in Intermediate, High, and Very High Risk Myelodysplastic Syndromes

Daniel Leonard, David Sallman, Kelly Pugh, Christopher S. Bell, Najla H. Al Ali, Uma Borate, Rami S. Komrokji, Andrew M. Brunner
Journal: Blood
Blood (2024) 144 (Supplement 1): 6714.
https://doi.org/10.1182/blood-2024-207880
Published: 2024
Journal Articles

A Phase 2B, Open-Label Multicenter Study of Tebapivat (AG-946), a Potent Pyruvate Kinase Activator, in Patients with Anemia Due to Lower-Risk Myelodysplastic Syndromes

Amer M. Zeidan, Mikkael A. Sekeres, Hanny Al-Samkari, Hetty E. Carraway, Amy E. DeZern, Moshe Mittelman, Meredith Little, Vanessa Beynon, Xiaoshu Dai, Sal Sommakia, Jenny M. Despotovic, Parija Patel, Melissa Dibacco, Bruno Fattizzo, Eytan M. Stein, David Sallman, Austin G. Kulasekararaj, Uwe Platzbecker, Pierre Fenaux
Journal: Blood
Blood (2024) 144 (Supplement 1): 6708.
https://doi.org/10.1182/blood-2024-203073
Published: 2024
Journal Articles

Trial in Progress: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 2 Study of AK117/Placebo in Combination with Azacitidine in Patients with Newly Diagnosed Higher-Risk Myelodysplastic Syndromes (AK117-205)

Amer M. Zeidan, Hongyan Tong, Zhijian Xiao, Praneeth Baratam, Ramzi Abboud, Christopher B. Benton, Joshua F Zeidner, Uma Borate, Wanxing Chai-Ho, Yonglin Lu, Jie Yang, Mingxiu Hu, Baiyong Li, Michelle Xia, David Sallman
Journal: Blood
Blood (2024) 144 (Supplement 1): 6705.
https://doi.org/10.1182/blood-2024-200541
Published: 2024
Journal Articles

High-Risk Myelodysplastic Syndrome (HR-MDS) Treated with a Hypomethylating Agent (HMA) and Venetoclax - Focus on Antifungal (AF) Prophylaxis and Molecular Subset Outcomes

Jeremy V. DiGennaro, Dimitrios Drekolias, Najla H. Al Ali, Onyee Chan, Seongseok Yun, Alison R. Walker, Zhuoer Xie, Eric Padron, Jeffrey E Lancet, Rami S. Komrokji, David Sallman
Journal: Blood
Blood (2024) 144 (Supplement 1): 1843.
https://doi.org/10.1182/blood-2024-208927
Published: 2024
Journal Articles

Ivosidenib in Patients with Mutant Isocitrate Dehydrogenase 1 (m IDH1 ) Relapsed/Refractory Myelodysplastic Syndromes: Update of the Phase 1 Substudy per the International Working Group 2023 Response Criteria

Yazan F Madanat, Amir T. Fathi, Guillermo Garcia-Manero, Gail J. Roboz, Justin M. Watts, Gabrielle T. Prince, Praneeth Baratam, Stephane De Botton, Anthony S. Stein, James M. Foran, Martha L. Arellano, David Sallman, Yuanye (Vickie) Zhang, Stephanie M. Kapsalis, Prapti A. Patel, Courtney D. DiNardo
Journal: Blood
Blood (2024) 144 (Supplement 1): 1841.
https://doi.org/10.1182/blood-2024-204862
Published: 2024
Journal Articles

Safety of Fedratinib As a Maintenance Strategy after Allogeneic Hematopoietic Cell Transplant for Myeloproliferative Neoplasms

Hany Elmariah, Jongphil Kim, Eric Hornfeck, Maria Urdiales Kouba, Farhad Khimani, Rawan Faramand, Sayeef Mirza, Joseph A. Pidala, Andrew T. Kuykendall, Rami S. Komrokji, Eric Padron, David Sallman, Alison R. Walker, Jeffrey E Lancet, Asmita Mishra, Jose L. Ochoa-Bayona, Lia Perez, Michael Nieder, Claudio Anasetti, Nelli Bejanyan, Taiga Nishihori
Journal: Blood
Blood (2024) 144 (Supplement 1): 1048.
https://doi.org/10.1182/blood-2024-210830
Published: 2024
Journal Articles

Measurable Residual Disease Monitoring By Duplex Sequencing for TP53 in the Post Allogeneic Stem Cell Transplantation Study with Eprenetapopt (APR-246) + Azacitidine Strongly Predicts Outcomes

David Sallman, Amy F McLemore, Rami S. Komrokji, Hany Elmariah, Andrew T. Kuykendall, Nelli Bejanyan, Onyee Chan, Rawan Faramand, Joseph A. Pidala, Sean J. Yoder, Lia Perez, Taiga Nishihori, Eric Padron, Hugo Francisco Fernandez, Jeffrey E Lancet, Asmita Mishra
Journal: Blood
Blood (2024) 144 (Supplement 1): 1046.
https://doi.org/10.1182/blood-2024-203903
Published: 2024
Journal Articles

A Prospective Evaluation of Impact of Disease, Treatment, Sex, and Race Disparities on Quality of Life and Financial Toxicity in Patients with Myelodysplastic Syndromes

Somedeb Ball, Najla H. Al Ali, Akriti G. Jain, Moazzam Shahzad, Junmin Whiting, Daniel Lastorino, Zhuoer Xie, Alison R. Walker, Onyee Chan, Eric Padron, Jongphil Kim, Jeffrey E Lancet, David Sallman, Sara M. Tinsley-Vance, Rami S. Komrokji
Journal: Blood
Blood (2024) 144 (Supplement 1): 532.
https://doi.org/10.1182/blood-2024-209273
Published: 2024
Journal Articles

Impact of Response to Hypomethylating Agent-Based Therapy on Survival Outcomes in the Context of Baseline Clinical-Molecular Risk and Transplant Status in Patients with Myelodysplastic Syndromes/Neoplasms (MDS): An Analysis from the International Consortium for MDS (icMDS) Validate Database

Benjamin Rolles, Jan Philipp Bewersdorf, Tariq Kewan, Ondrej Blaha, Jessica M. Stempel, Luca Lanino, Najla H. Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L. Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Christine M. McMahon, Rory M. Shallis, Joshua F Zeidner, Michael R. Savona, Stacey M. Frumm, Shougat Barua, Namrata S. Chandhok, Constantine Logothetis, Aram Bidikian, Ted M. Getz, Gail J. Roboz, Eunice S. Wang, Amyah C. Harris, Maria L Amaya, Hayley Hawkins, Somedeb Ball, Justin Grenet, Zhuoer Xie, Yazan F Madanat, Yasmin Abaza, Talha Badar, Torsten Haferlach, Jaroslaw Maciejewski, David Sallman, Anoop K Enjeti, Kamal Al-Rabi, Khalid Halahleh, Devendra Hiwase, Maria Diez-Campelo, David Valcarcel, Claudia Haferlach, Lisa Pleyer, Ioannis Kotsianidis, Vassiliki Pappa, Valeria Santini, Angela Consagra, Aref Al-Kali, Seishi Ogawa, Yasuhito Nannya, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 664.
https://doi.org/10.1182/blood-2024-208034
Published: 2024
Journal Articles

Preliminary Safety, Efficacy, and Molecular Characterization of Emavusertib (CA-4948) in Relapsed/Refractory Acute Myeloid Leukemia Patients

Eric S. Winer, David Sallman, Adolfo De la Fuente Burguera, Amit Verma, Katharina Goetze, Yasmin Abaza, James P. Dugan, Thomas Cluzeau, Eduardo Rodriguez Arboli, Alice Mims, Stefanie Groepper, Itay Zilbershatz, Jane L. Liesveld, Walter Fiedler, Stefano R Tarantolo, Lionel Ades, Nikolaos Papadantonakis, Christoph Schliemann, Gaurav S Choudhary, Maureen Lane, Wanying Zhao, Ashish Jain, Cole Gallagher, Guillermo Garcia-Manero
Journal: Blood
Blood (2024) 144 (Supplement 1): 737.
https://doi.org/10.1182/blood-2024-207953
Published: 2024
Journal Articles

Non-Engrafting CD8-Depleted Human Leukocyte Antigen (HLA) Mismatched Unrelated Donor Lymphocyte Infusion (DLI) Achieves Remissions in Transplant-Naive Myelodysplastic Syndrome (MDS) and Secondary Acute Myeloid Leukemia (sAML)

Hany Elmariah, Jongphil Kim, Kayla Reid, Christopher Cubitt, Andrew T. Kuykendall, Jeffrey E Lancet, Rami S. Komrokji, David Sallman, Eric Padron, Onyee Chan, Kendra L. Sweet, Alison R. Walker, Albert J Ribickas, Stephanie Dormesy, Debra A Kessler, Priscilla M Abedu, Asmita Mishra, Farhad Khimani, Lia Perez, Joseph A. Pidala, Claudio Anasetti, Ephraim Joseph Fuchs, Philip Imus, Michael D. Jain, Frederick L. Locke, Marco Davila, Nelli Bejanyan, Amy E. DeZern
Journal: Blood
Blood (2024) 144 (Supplement 1): 2071.
https://doi.org/10.1182/blood-2024-208021
Published: 2024
Journal Articles

A Phase 1 Study of CPX-351 Plus Gilteritinib in Relapsed or Refractory FLT3 -Mutated Acute Myeloid Leukemia

Onyee Chan, Kendra L. Sweet, Jhada-Kai Hunter, Somedeb Ball, Qianxing Mo, Zhuoer Xie, Seongseok Yun, Andrew T. Kuykendall, Eric Padron, Alison R. Walker, Rami S. Komrokji, Jeffrey E Lancet, David Sallman
Journal: Blood
Blood (2024) 144 (Supplement 1): 1520.
https://doi.org/10.1182/blood-2024-205977
Published: 2024
Journal Articles

Real World Outcomes of Oral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia: A Single Center Experience

Fatima Tuz Zahra, Faustine Ong, Daniel Walgenbach, Onyee Chan, Katherine Tobon, Jeffrey E Lancet, David Sallman, Rami S. Komrokji, Andrew T. Kuykendall, Eric Padron, Alison R. Walker, Zhuoer Xie, Seongseok Yun
Journal: Blood
Blood (2024) 144 (Supplement 1): 2415.
https://doi.org/10.1182/blood-2024-202576
Published: 2024
Journal Articles

A Molecular-Based Ecosystem to Improve Personalized Medicine in Patients with Chronic Myelomonocytic Leukemia (CMML)

Luca Lanino, Anthony M. Hunter, Nico Gagelmann, Marie Robin, Claudia Sala, Daniele Dall'Olio, Carmelo Gurnari, Lorenzo Dall'Olio, Yu-Hung Wang, Lisa Pleyer, Blanca Xicoy, Guillermo Montalban-Bravo, Lee-Yung Shih, Tamanna Haque, Omar Abdel-Wahab, Klaus Geissler, Alex Bataller, Alexandre Bazinet, Manja Meggendorfer, Ilaria Carola Casetti, Elisabetta Sauta, Erica Travaglino, Laura Palomo, Lurdes Zamora, David Quintela, Andres Jerez, Elena Cornejo, Paloma Garcia Martin, Marina Díaz-Beyá, Alejandro Avendaño Pita, Veronica Roldan, Dolly Viviana Fiallo Suarez, Estefania Cerezo Velasco, Marisa Calabuig, Esperanza Such, Guillermo Sanz, Anne Sophie Kubasch, Cristina Castilla-Llorente, Claude-Éric Bulabois, Laetitia Souchet, Hussein Awada, Massimo Bernardi, Patrizia Chiusolo, Antonio Curti, Luisa Giaccone, Francesco Onida, Lorenza Maria Borin, Francesco Passamonti, Elisa Diral, Vladan Vucinic, Gregorio Maria Bergonzi, Maria Teresa Voso, Hsin-An Hou, Wen-Chien Chou, Chi-Yuan Yao, Chien-Chin Lin, Hwei-Fang Tien, Alessia Campagna, Marta Ubezio, Antonio Russo, Gabriele Todisco, Giulia Maggioni, Cristina Astrid Tentori, Alessandro Buizza, Gianluca Asti, Matteo Zampini, Elena Riva, Mattia Delleani, Angela Consagra, Francesca Ficara, Armando Santoro, Luciana Carota, Tiziana Sanavia, Cesare Rollo, Ahmad Kiwan, Jennifer VanOudenhove, Piero Fariselli, Najla H. Al Ali, David Sallman, Wolfgang Kern, Guillermo Garcia-Manero, Swapna Thota, Elizabeth A. Griffiths, Matilde Yung Follo, Carlo Finelli, Uwe Platzbecker, Francesc Sole, Maria Diez-Campelo, Jaroslaw Maciejewski, Rafael Bejar, Felicitas R. Thol, Nicolaus Kröger, Pierre Fenaux, Raphael Itzykson, Timothy Aaron Graubert, Michaela Fontenay, Amer M. Zeidan, Rami S. Komrokji, Valeria Santini, Torsten Haferlach, Ulrich Germing, Saverio D'Amico, Gastone Castellani, Mrinal M. Patnaik, Eric Solary, Eric Padron, Matteo Giovanni Della Porta
Journal: Blood
Blood (2024) 144 (Supplement 1): 1003.
https://doi.org/10.1182/blood-2024-200104
Published: 2024
Journal Articles

A Phase 2 Study of Fedratinib in Patients with MDS/MPN and Chronic Neutrophilic Leukemia

Andrew T. Kuykendall, Tania Jain, Abhay Singh, Kristen M. Pettit, Quan Lovette, Joan McFadden Cain, Tracy Ann Cinalli, Mary Gallagher, David Sallman, Qianxing Mo, Ling Zhang, Onyee Chan, Alison R. Walker, Zhuoer Xie, Jeffrey E Lancet, Maria Balasis, Seongseok Yun, Eric Padron, Rami S. Komrokji
Journal: Blood
Blood (2024) 144 (Supplement 1): 481.
https://doi.org/10.1182/blood-2024-210743
Published: 2024