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Lucille Ferrante
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Journal Articles

Phase 1b Study of Menin-KMT2A Inhibitor Bleximenib in Combination with Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia with KMT2Ar or NPM1 Alterations

Christian Recher, Jenny O'Nions, Ibrahim Aldoss, Ana Alfonso Pierola, Alicia Allred, Juan Manuel Alonso-Dominguez, Laura Barreyro, Pierre Bories, Martin Curtis, Nikki Daskalakis, Matteo Giovanni Della Porta, Hartmut Döhner, Amber D'Souza, James P. Dugan, Jordi Esteve Reyner, Matthew Exum, Amir T. Fathi, Pasquale L. Fedele, Lucille Ferrante, Stan Gaj, Sylvain Garciaz, Ana Garrido, Sara Garrido Paniagua, Christina Guttke, Emmanuel Gyan, Brett Hiebert, Elias Jabbour, Madlen Jentzsch, Hagop M. Kantarjian, Marina Konopleva, Jan Krönke, Min Chul Kwon, Christina Loefgren, Oliver Lomas, Valentina Mancini, Ioannis Mantzaris, Giovanni Martinelli, Daniel Morillo Giles, Joseph Murphy, Kathryn Packman, Cristina Papayannidis, Ulrike Philippar, Uwe Platzbecker, Sravanti Rangaraju, Christoph Röllig, Olga Salamero, Madhu Sanga, Tim Sauer, Emma Searle, Natalia Tovar, Trevor Tucker, Nicolas Vallet, Lachlin Vaughan, Gala Vega, Paresh Vyas, Andrew Wei
Journal: Blood
Blood (2024) 144 (Supplement 1): 215.
https://doi.org/10.1182/blood-2024-207072
Published: 2024
Journal Articles

Bleximenib Dose Optimization and Determination of RP2D from a Phase 1 Study in Relapsed/Refractory Acute Leukemia Patients with KMT2A and NPM1 Alterations

Emma Searle, Christian Recher, Maher Abdul-Hay, Sameem Abedin, Ibrahim Aldoss, Ana Alfonso Pierola, Juan M. Alonso-Dominguez, Patrice Chevallier, Carrye Cost, Nikki Daskalakis, Richard Dillon, Neil Dunavin, Jordi Esteve, Amir T. Fathi, Pasquale L. Fedele, Lucille Ferrante, Stan Gaj, Christina Guttke, Emmanuel Gyan, Brett Hiebert, Elias Jabbour, Hagop M. Kantarjian, Min Chul Kwon, Anita J Kumar, Teng Fong Ng, Kathryn Packman, Ulrike Philippar, Arnaud Pigneux, Olga Salamero, Madhu Sanga, Prathap Nagaraja Shastri, Richard M. Stone, Peter Tan, Trevor Tucker, Paresh Vyas, Sylvain Garciaz
Journal: Blood
Blood (2024) 144 (Supplement 1): 212.
https://doi.org/10.1182/blood-2024-207106
Published: 2024
Journal Articles

Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A - and NPM1 -altered leukemias

Min Chul Kwon, Jan Willem Thuring, Olivier Querolle, Xuedong Dai, Tinne Verhulst, Vineet Pande, Ann Marien, Dries Goffin, Daniela V. Wenge, Hong Yue, Jevon A. Cutler, Cyrus Jin, Florian Perner, Shanna M. Hogeling, Paul L. Shaffer, Frank Jacobs, Petra Vinken, Wei Cai, Vikki Keersmaekers, Filmon Eyassu, Balpreet Bhogal, Karin Verstraeten, Sara El Ashkar, Jennifer A. Perry, Prathiba Jayaguru, Laura Barreyro, Anna Kuchnio, Nicolas Darville, Daniel Krosky, Gregor Urbanietz, Bie Verbist, James P. Edwards, Glenn S. Cowley, Robert Kirkpatrick, Ruth Steele, Lucille Ferrante, Christina Guttke, Nikki Daskalakis, E. Christine Pietsch, David M. Wilson, Ricardo Attar, Yusri Elsayed, Eric S. Fischer, Jan Jacob Schuringa, Scott A. Armstrong, Kathryn Packman, Ulrike Philippar
Journal: Blood
Blood (2024) 144 (11): 1206–1220.
https://doi.org/10.1182/blood.2023022480
Published: 2024
Includes: Supplemental data
Journal Articles

A First-in-Human Phase 1 Study of the Menin-KMT2A (MLL1) Inhibitor JNJ-75276617 in Adult Patients with Relapsed/Refractory Acute Leukemia Harboring KMT2A or NPM1 Alterations

Elias Jabbour, Emma Searle, Maher Abdul-Hay, Sameem Abedin, Ibrahim Aldoss, Ana Alfonso Piérola, Juan Manuel Alonso-Dominguez, Patrice Chevallier, Carrye Cost, Nikki Daskalakis, Richard Dillon, Neil Dunavin, Jordi Esteve, Amir T. Fathi, Pasquale L. Fedele, Lucille Ferrante, Sylvain Garciaz, Christina Guttke, Emmanuel Gyan, Brett Hiebert, Min Chul Kwon, Jonathan Miller, Teng Fong Ng, Kathryn Packman, Ulrike Philippar, Arnaud Pigneux, Christian Recher, Olga Salamero, Madhu Sanga, Richard M Stone, Peter Tan, Jan Willem Thuring, Trevor Tucker, Paresh Vyas
Journal: Blood
Blood (2023) 142 (Supplement 1): 57.
https://doi.org/10.1182/blood-2023-172422
Published: 2023
Journal Articles

Preclinical Efficacy of the Menin-KMT2A Inhibitor JNJ-75276617 in Combination with Venetoclax and Azacitidine in AML

Min Chul Kwon, Tinne Verhulst, Dries Goffin, Ann Marien, Bie Verbist, Christina Guttke, Jan Willem Thuring, Lucille Ferrante, Nikki Daskalakis, E. Christine Pietsch, Yusri Elsayed, Kathryn Packman, Ulrike Philippar
Journal: Blood
Blood (2023) 142 (Supplement 1): 4167.
https://doi.org/10.1182/blood-2023-186204
Published: 2023
Journal Articles

Prognostic Testing and Treatment Approaches in Patients with Chronic Lymphocytic Leukemia: Clinical Experience from an Interim Analysis of the informCLL TM Real-World Registry

Anthony R. Mato, MDMSCE, Jacqueline C. Barrientos, MD MS, Danielle M. Brander, MD, John M. Pagel, MD PhD, Meghan Gutierrez, Karen Kadish, MSN, Brian Tomlinson, MPA, Nilanjan Ghosh, MD PhD, Nick Giafis, PhD, David Ipe, Sandhya Upasani, Murali Sundaram, MBA, PhD, Lucille Ferrante, MD, Carlos Amaya-Chanaga, MD, Reethi Iyengar, PhD, Jeff Sharman, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4425.
https://doi.org/10.1182/blood-2018-99-110566
Published: 2018
Journal Articles

Chronic Lymphocytic Leukemia Treatment Patterns, Dosing, and Sequencing in the Era of Novel Targeted Therapies: Interim Analysis Results from the Prospective informCLL TM Real-World Registry

Jeff Sharman, MD, Jacqueline C. Barrientos, MD MS, Danielle M. Brander, MD, John M. Pagel, MD PhD, Meghan Gutierrez, Karen Kadish, MSN, Brian Tomlinson, MPA, Nilanjan Ghosh, MD PhD, Nick Giafis, PhD, David Ipe, Sandhya Upasani, Murali Sundaram, MBA, PhD, Lucille Ferrante, MD, Carlos Amaya-Chanaga, MD, Reethi Iyengar, PhD, Anthony R. Mato, MD MSCE
Journal: Blood
Blood (2018) 132 (Supplement 1): 1872.
https://doi.org/10.1182/blood-2018-99-110562
Published: 2018
Journal Articles

A Validated Risk Model for Overall Survival in Relapsed/Refractory Chronic Lymphocytic Leukemia Applicable to Patients Treated with Novel Therapies and Standard of Care

Jacob D. Soumerai, MD, Ai Ni, PhD, Mohamed Darif, PhD, Anil Londhe, PhD, Guan Xing, PhD, Julie Huang, PhD, Ming Lin, PhD, John C. Byrd, MD, Asher A. Chanan-Khan, MD, Richard R. Furman, MD, Michael Hallek, MD, Peter Hillmen, MBChB, PhD, Jeffrey Jones, MD, Jeffrey P. Sharman, MD, Lucille Ferrante, MD, Vijay Reddy, MD PhD, Lyndah K. Dreiling, MD, Henry Adewoye, MD, Ronald Dubowy, MD, Angela Howes, PhD, Danelle F. James, MD MAS, Andrew D. Zelenetz, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4303.
https://doi.org/10.1182/blood.V130.Suppl_1.4303.4303
Published: 2017
Journal Articles

Safety Results from the United States Cohort of the Ibrutinib Early Access Treatment Protocol (EAP: MCL4001) in Patients with Relapsed or Refractory Mantle Cell Lymphoma

Peter Martin, MD, Andre Goy, MD, Radhakrishnan Ramchandren, MD, Lucille Ferrante, MD, Vijay Reddy, MD PhD, Anil Londhe, Mark Wildgust, Tracy McGowan, MD, Nancy L Bartlett, MD
Journal: Blood
Blood (2014) 124 (21): 4461.
https://doi.org/10.1182/blood.V124.21.4461.4461
Published: 2014