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Hagop M. Kantarjian
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Journal Articles

Blood-based proteomic profiling identifies OSMR as a novel biomarker of AML outcomes

Open Access
Patrick K. Reville, Bofei Wang, Jennifer Marvin-Peek, Bin Yuan, Yu-An Kuo, Araceli Garza, Jessica Root, Wei Qiao, Andrea Arruda, Ivo Veletic, Yiwei Liu, Nicholas J. Short, Courtney D. DiNardo, Tapan M. Kadia, Naval G. Daver, Philip L. Lorenzi, Koji Sasaki, Steven Kornblau, Mark D. Minden, Farhad Ravandi, Hagop M. Kantarjian, Hussein A. Abbas
Journal: Blood
Blood (2025) 145 (25): 3015–3029.
https://doi.org/10.1182/blood.2024027244
Published: 2025
Includes: Supplemental data
Journal Articles

Clonal Basis of Resistance and Response to Ivosidenib Combination Therapies Is Established Early during Treatment in IDH1 -Mutated Myeloid Malignancies

Free
Sven Turkalj, Bilyana Stoilova, Angus J Groom, Felix A Radtke, Rabea Mecklenbrauck, Niels Asger Jakobsen, Curtis A Lachowiez, Marlen Metzner, Batchimeg Usukhbayar, Mirian Angulo Salazar, Zhihong Zeng, Sanam Loghavi, Jennifer Marvin-Peek, Verena Körber, Farhad Ravandi, Ghayas C. Issa, Tapan M. Kadia, Vasiliki Symeonidou, Anne De Groot, Hagop M. Kantarjian, Koichi Takahashi, Marina Konopleva, Courtney D. DiNardo, Paresh Vyas
Journal: Blood
Blood (2024) 144 (Supplement 1): 642.
https://doi.org/10.1182/blood-2024-201970
Published: 2024
Journal Articles

Safety and Efficacy of G-CSF with Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia: A Subgroup Analysis of the Phase II Trial of Venetoclax in Combination with Cladribine, Idarubicin, and Cytarabine

Free
Ian M. Bouligny, Hagop M. Kantarjian, Musa Yilmaz, Naval Daver, Gautam Borthakur, Courtney D. DiNardo, Guillermo Montalban-Bravo, Nicholas J. Short, Yesid Alvarado Valero, Nitin Jain, Naveen Pemmaraju, Danielle Hammond, Kelly S. Chien, Koichi Takahashi, Ghayas C. Issa, Hussein A. Abbas, Elias Jabbour, Guillermo Garcia-Manero, Farhad Ravandi, Tapan M. Kadia
Journal: Blood
Blood (2024) 144 (Supplement 1): 446.
https://doi.org/10.1182/blood-2024-203938
Published: 2024
Journal Articles

A Phase II Trial of Venetoclax in Combination with Cladribine, Idarubicin, and Cytarabine in Newly Diagnosed Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome

Free
Ian M. Bouligny, Hagop M. Kantarjian, Musa Yilmaz, Naval Daver, Gautam Borthakur, Courtney D. DiNardo, Guillermo Montalban-Bravo, Nicholas J. Short, Yesid Alvarado Valero, Elias Jabbour, Nitin Jain, Naveen Pemmaraju, Danielle Hammond, Kelly S. Chien, Koichi Takahashi, Ghayas C. Issa, Hussein A. Abbas, Guillermo Garcia-Manero, Farhad Ravandi, Tapan M. Kadia
Journal: Blood
Blood (2024) 144 (Supplement 1): 734.
https://doi.org/10.1182/blood-2024-203459
Published: 2024
Journal Articles

Establishing Benchmarks for Relapse-Free and Overall Survival Among Patients (Pts) with Newly Diagnosed AML Not Undergoing Allogeneic Stem Cell Transplantation (SCT) in First Remission

Free
Eitan Kugler, Hagop M. Kantarjian, Alexandre Bazinet, Wei-Ying Jen, Naval Daver, Courtney D. DiNardo, Nicholas J. Short, Jayastu Senapati, Gautam Borthakur, Naveen Pemmaraju, Ghayas C. Issa, Alex Bataller, Patrick K. Reville, Guillermo Garcia-Manero, Farhad Ravandi, Tapan M. Kadia
Journal: Blood
Blood (2024) 144 (Supplement 1): 2861.
https://doi.org/10.1182/blood-2024-199903
Published: 2024
Journal Articles

Dose Optimization of Inotuzumab Ozogamicin in Adult Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

Free
Daniel J. DeAngelo, Ying Chen, Ryan D. Cassaday, Jennifer Hibma, Derek Z Yang, May Garrett, Fan Zhang, Svetoslav H Dimitrov, Erik Vandendries, Hagop M. Kantarjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 732.
https://doi.org/10.1182/blood-2024-194244
Published: 2024
Journal Articles

Incidence, Characteristics, and Outcomes of Patients with Newly Diagnosed, De Novo KIT -Mutated Non-Core Binding Factor Acute Myeloid Leukemia without Systemic Mastocytosis

Free
Eitan Kugler, Sanam Loghavi, Farhad Ravandi, Courtney D. DiNardo, Naval Daver, Tapan M. Kadia, Gautam Borthakur, Ghayas C. Issa, Hussein A. Abbas, Prithviraj Bose, Jayastu Senapati, Hagop M. Kantarjian, Nicholas J. Short
Journal: Blood
Blood (2024) 144 (Supplement 1): 2857.
https://doi.org/10.1182/blood-2024-199917
Published: 2024
Journal Articles

Clinical Outcomes Associated with NPM1 Mutations in Newly Diagnosed AML

Free
Aziz Farhat, Hagop M. Kantarjian, Koji Sasaki, Nicholas J. Short, Branko Cuglievan, Sanam Loghavi, Keyur P. Patel, Alex Bataller, Musa Yilmaz, Guillermo Montalban-Bravo, Danielle Hammond, Naveen Pemmaraju, Naval Daver, Farhad Ravandi, Elias Jabbour, Tapan M. Kadia, Gautam Borthakur, Guillermo Garcia-Manero, Courtney D. DiNardo, Ghayas C. Issa
Journal: Blood
Blood (2024) 144 (Supplement 1): 2853.
https://doi.org/10.1182/blood-2024-205504
Published: 2024
Journal Articles

Older Age and TP53 Mutations Are Predictors for the Development of Therapy-Related Myeloid Neoplasms in Adults Undergoing Frontline Therapy for Acute Lymphoblastic Leukemia

Free
Roberta Santos Azevedo, Hagop M. Kantarjian, Koichi Takahashi, Cedric Christophe Nasnas, Sanam Loghavi, Nitin Jain, Fadi G. Haddad, Jayastu Senapati, Ghayas C. Issa, Hussein A. Abbas, Tapan M. Kadia, Kelly S. Chien, Guillermo Montalban-Bravo, Rebecca Garris, Farhad Ravandi, Elias Jabbour, Nicholas J. Short
Journal: Blood
Blood (2024) 144 (Supplement 1): 728.
https://doi.org/10.1182/blood-2024-207745
Published: 2024
Journal Articles

Early Achievement of Deep Measurable Residual Disease (MRD) Negativity Identifies Patients with B-Cell Acute Lymphoblastic Leukemia (ALL) Who Have Excellent Long-Term Outcomes and Do Not Benefit from Allogeneic Stem Cell Transplant, Irrespective of Baseline High-Risk Cytomolecular Features

Free
Walid Macaron, Elias Jabbour, Nitin Jain, Fadi G. Haddad, Jayastu Senapati, Partow Kebriaei, Eitan Kugler, Kelly S. Chien, Ghayas C. Issa, Jairo Matthews, Rebecca Garris, Farhad Ravandi, Hagop M. Kantarjian, Nicholas J. Short
Journal: Blood
Blood (2024) 144 (Supplement 1): 727.
https://doi.org/10.1182/blood-2024-203929
Published: 2024
Journal Articles

Age-Related Prognoses of Genetic Subtypes in B-Cell Acute Lymphoblastic Leukemia/Lymphoma (B-ALL): Insights from a Decade of National Data

Free
Ting Zhou, Nicholas J. Short, Nitin Jain, Keyur P. Patel, Elias Jabbour, Hagop M. Kantarjian, L. Jeffrey Medeiros, Bryan Iorgulescu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1456.
https://doi.org/10.1182/blood-2024-208340
Published: 2024
Journal Articles

Clonal Origin of Therapy-Related Myeloid Neoplasms after Autologous Stem Cell Transplant

Free
Hidetaka Uryu, Koichi Saeki, Hiroshi Haeno, Chiraag Kapadia, Ken Furudate, Jyoti Nangalia, Michael Spencer Chapman, Li Zhao, Joanne Hsu, Chong Zhao, Shujuan Chen, Tomoyuki Tanaka, Zongrui Li, Hui Yang, Courtney D. DiNardo, Naval Daver, Naveen Pemmaraju, Nitin Jain, Farhad Ravandi, Jianhua Zhang, Xingzhi Song, Erika Thompson, Hongli Tang, Latasha Little, Curtis Gumbs, Robert Z. Orlowski, Muzaffar H. Qazilbash, Kapil N. Bhalla, Simona Colla, Hagop M. Kantarjian, Rashmi Kanagal-Shamanna, Carlos E. Bueso-Ramos, Daisuke Nakada, Jeffrey J. Molldrem, Gheath Alatrash, Andrew Futreal, Elizabeth J. Shpall, Margaret Goodell, Guillermo Garcia-Manero, Koichi Takahashi
Journal: Blood
Blood (2024) 144 (Supplement 1): 346.
https://doi.org/10.1182/blood-2024-208106
Published: 2024
Journal Articles

Blood-Based Proteomic Profiling Identifies Osmr As a Novel Biomarker

Free
Hussein A. Abbas, Bofei Wang, Jennifer Marvin-Peek, Bin Yuan, Araceli Isabella Garza, Jessica Lynn Root, Andrea Arruda, Yiwei Liu, Courtney D. DiNardo, Tapan M. Kadia, Naval Daver, Philip L Lorenzi, Koji Sasaki, Steven M. Kornblau, Mark D. Minden, Farhad Ravandi, Hagop M. Kantarjian, Patrick K. Reville
Journal: Blood
Blood (2024) 144 (Supplement 1): 2912.
https://doi.org/10.1182/blood-2024-201725
Published: 2024
Journal Articles

Ponatinib Monotherapy after Combination with Chemotherapy in Patients with Newly Diagnosed Ph+ ALL: Post Hoc Subgroup Analysis of the Phase 3 Phallcon Study

Free
Elias Jabbour, Hagop M. Kantarjian, Ibrahim Aldoss, Pau Montesinos, Jessica T. Leonard, David Gomez-Almaguer, Maria R. Baer, Carlo Gambacorti-Passerini, James McCloskey, Yosuke Minami, Cristina Papayannidis, Vanderson Rocha, Philippe Rousselot, Pankit Vachhani, Eunice S. Wang, Lin Yang, Meliessa Hennessy, Alexander Vorog, Niti Patel, Tammie Yeh, Josep-Maria Ribera
Journal: Blood
Blood (2024) 144 (Supplement 1): 2821.
https://doi.org/10.1182/blood-2024-208504
Published: 2024
Journal Articles

Less May be More: The Impact of Post-Remission Intensive (IC) Consolidation Cycles on Outcomes in Newly Diagnosed Acute Myeloid Leukemia Receiving IC + Venetoclax

Free
Jennifer Marvin-Peek, Courtney D. DiNardo, Wei-Ying Jen, Nicholas J. Short, Yesid Alvarado Valero, Gautam Borthakur, Naval Daver, Eitan Kugler, Alexandre Bazinet, Hussein A. Abbas, Musa Yilmaz, Guillermo Garcia-Manero, Hagop M. Kantarjian, Tapan M. Kadia
Journal: Blood
Blood (2024) 144 (Supplement 1): 1472.
https://doi.org/10.1182/blood-2024-202405
Published: 2024
Journal Articles

A Phase Ib, Open-Label Study of Add on Therapy with CK0804 in Participants with Myelofibrosis and Suboptimal Response to Ruxolitinib

Free
Lucia Masarova, Meixian Huang, Swati Goel, Sharon Bledsoe, Naveen Pemmaraju, Tapan M. Kadia, Prithviraj Bose, Jo Ishizawa, Guillermo Montalban-Bravo, Mi-Ae Lyu, Tara Sadeghi, Simrit Parmar, Christopher R. Flowers, Hagop M. Kantarjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 999.
https://doi.org/10.1182/blood-2024-211587
Published: 2024
Journal Articles

A Phase I Study of Nivolumab in Combination with Ipilimumab for the Treatment of Patients with High Risk or Refractory/Relapsed Acute Myeloid Leukemia Following Allogeneic Stem Cell Transplantation

Free
Gheath Alatrash, Cristina Knape, Laura Whited, Dawen Sui, Cara L Haymaker, Jason Yeh, Megan Marcotulli, Pariya Sukhumalchandra, Lisa St. John, Hsinyi Lu, Daniela E. Duenas, Ignacio Wistuba, Julia Mendoza Perez, Beatriz Sanchez Espiridion, Roland L. Bassett, Tapan M. Kadia, Courtney D. DiNardo, Farhad Ravandi, Jeremy Ramdial, Rohtesh S. Mehta, Amin M. Alousi, Betul Oran, Issa F. Khouri, Qaiser Bashir, Chitra Hosing, Muzaffar H. Qazilbash, Jin S. Im, Partow Kebriaei, Pavan Bachireddy, Jeffrey J. Molldrem, Jeffrey L. Jorgensen, Sa A. Wang, Wei WANG, Uday Popat, Elizabeth J. Shpall, Richard E. Champlin, Hagop M. Kantarjian, Naval Daver
Journal: Blood
Blood (2024) 144 (Supplement 1): 1047.
https://doi.org/10.1182/blood-2024-211343
Published: 2024
Journal Articles

Long-Term Survival Outcomes and Cytogenetic/Molecular Patterns of Relapse in Adults with FLT3 -Mutated AML Receiving Frontline Triplet Therapy with a Hypomethylating Agent, Venetoclax and FLT3 Inhibitor

Free
Nicholas J. Short, Sanam Loghavi, Musa Yilmaz, Omer Karrar, Joseph E. Jabbour, Courtney D. DiNardo, Tapan M. Kadia, Gautam Borthakur, Ghayas C. Issa, Hussein A. Abbas, Marina Konopleva, Farhad Ravandi, Hagop M. Kantarjian, Naval Daver
Journal: Blood
Blood (2024) 144 (Supplement 1): 220.
https://doi.org/10.1182/blood-2024-210891
Published: 2024
Journal Articles

A Phase Ib/II Study of Ivosidenib with Venetoclax ± Azacitidine in IDH1-Mutated Hematologic Malignancies: A 2024 Update

Free
Jennifer Marvin-Peek, Jacqueline S. Garcia, Gautam Borthakur, Guillermo Garcia-Manero, Nicholas J. Short, Tapan M. Kadia, Sanam Loghavi, Lucia Masarova, Naval Daver, Abhishek Maiti, Koichi Takahashi, Koji Sasaki, Danielle Hammond, George Donovan Tippett, Dylan Wilson, Kelly S. Chien, Prithviraj Bose, Patrick K. Reville, Curtis A Lachowiez, Akriti G. Jain, Ghayas C. Issa, Nitin Jain, Guillermo Montalban-Bravo, Marlise R. Luskin, Hetty E. Carraway, Farhad Ravandi, Hagop M. Kantarjian, Courtney D. DiNardo
Journal: Blood
Blood (2024) 144 (Supplement 1): 219.
https://doi.org/10.1182/blood-2024-200393
Published: 2024
Journal Articles

Phase I/II Study of the All-Oral Combination of Revumenib (SNDX-5613) with Decitabine/Cedazuridine (ASTX727) and Venetoclax (SAVE) in R/R AML

Free
Ghayas C. Issa, Branko Cuglievan, Naval Daver, Courtney D. DiNardo, Aziz Farhat, Nicholas J. Short, David McCall, Allison Pike, Sheila Tan, Brianna Kammerer, Aimee Marshal, Musa Yilmaz, Tapan M. Kadia, Naveen Pemmaraju, Maro Ohanian, Hussein A. Abbas, Abhishek Maiti, Alexandre Bazinet, Elias Jabbour, Koji Sasaki, Gautam Borthakur, Guillermo Montalban-Bravo, Nitin Jain, Yesid Alvarado Valero, Farhad Ravandi, Guillermo Garcia-Manero, Michael Andreeff, Hagop M. Kantarjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 216.
https://doi.org/10.1182/blood-2024-204375
Published: 2024