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Journal Articles

BRAF -Mutated Acute Myeloid Leukemia (AML) Represents a Prognostically Poor Subgroup Enriched for Myelodysplasia-Related Subtypes and Distinct from Other RAS Pathway Mutant AML

Blood (2024) 144 (Supplement 1): 2921.

https://doi.org/10.1182/blood-2024-210110

Published: 2024

Journal Articles

Genomic Profiling of T-Cell Acute Lymphoblastic Leukemia/Lymphoma (T-ALL) for Identification of Driver Aberrations Using Combined Next Generation Sequencing and Optical Genome Mapping in Clinical Diagnostic Laboratory

Iman Sarami, Ruchi Singhal, Mark Routbort, Koji Sasaki, Daniel Domogala III, Gokce A. Toruner, Shibu Ninan, Nitin Jain, Keyur P. Patel, Elias Jabbour, Hagop M. Kantarjian, Carlos E. Bueso-Ramos, L. Jeffrey Medeiros, Raja Luthra, Guilin Tang, Rashmi Kanagal-Shamanna

Blood (2024) 144 (Supplement 1): 4224.

https://doi.org/10.1182/blood-2024-211561

Published: 2024

Journal Articles

BRAF -Mutated Acute Myeloid Leukemia (AML) Represents a Distinct, Prognostically Poor Subgroup Enriched in Myelodysplasia-Related (MR-)AML

Blood (2023) 142 (Supplement 1): 1575.

https://doi.org/10.1182/blood-2023-185135

Published: 2023

Journal Articles

Clinical and Prognostic Implications of WT1 Mutations in De Novo and Relapsed Acute Myeloid Leukemia

Blood (2023) 142 (Supplement 1): 959.

https://doi.org/10.1182/blood-2023-188319

Published: 2023

Journal Articles

Mutation Spectrum, Characteristics and Impact of Mutation Profiling on Prognosis, Outcome and Treatment Responses in Patients (pts) with Mantle Cell Lymphoma

Blood (2022) 140 (Supplement 1): 3598–3600.

https://doi.org/10.1182/blood-2022-162806

Published: 2022

Journal Articles

The Adverse Effect of Myelodysplasia-Related Mutations in De Novo Acute Myeloid Leukemia Is Associated with Higher Variant Allelic Frequency (VAF): A Proposal for a Numeric Cutoff for Variant Allelic Frequency

Blood (2022) 140 (Supplement 1): 6306–6308.

https://doi.org/10.1182/blood-2022-164494

Published: 2022

Journal Articles

Clinical and Molecular Characterization of Newly Diagnosed IDH/TP53 Co-Mutated AML and Impact of Genomically Sensitive Treatment Strategies

Sangeetha Venugopal, Sanam Loghavi, Mark Routbort, Fatima Zahra Jelloul, Rashmi Kanagal-Shamanna, Sherry A. Pierce, Ghayas C. Issa, Hussein A Abbas, Koji Sasaki, Koichi Takahashi, Naval Daver, Farhad Ravandi, Hagop Kantarjian, Courtney D. DiNardo

Blood (2022) 140 (Supplement 1): 6328–6330.

https://doi.org/10.1182/blood-2022-169778

Published: 2022

Journal Articles

Homologous Recombination DNA Repair Deficiency Score Is Independent Prognostic Variable in Myelodysplastic Syndrome/ Acute Myeloid Leukemia with Complex Karyotype

Ha Nguyen, Koji Sasaki, Farhad Ravandi, Rajyalakshmi Luthra, Keyur P. Patel, Sanam Loghavi, Fatima Zahra Jelloul, Mark Routbort, Awdesh Kalia, Guillermo Montalban-Bravo, Kelly S. Chien, Peter Hu, Musa Yilmaz, Carlos E. Bueso-Ramos, L. Jeffrey Medeiros, Guillermo Garcia-Manero, Rashmi Kanagal-Shamanna

Blood (2022) 140 (Supplement 1): 1353–1354.

https://doi.org/10.1182/blood-2022-168999

Published: 2022

Journal Articles

TP53 copy number and protein expression inform mutation status across risk categories in acute myeloid leukemia

Mehrnoosh Tashakori, Tapan Kadia, Sanam Loghavi, Naval Daver, Rashmi Kanagal-Shamanna, Sherry Pierce, Dawen Sui, Peng Wei, Farnoosh Khodakarami, Zhenya Tang, Mark Routbort, Carol A. Bivins, Elias J. Jabbour, L. Jeffrey Medeiros, Kapil Bhalla, Hagop M. Kantarjian, Farhad Ravandi, Joseph D. Khoury

Blood (2022) 140 (1): 58–72.

https://doi.org/10.1182/blood.2021013983

Published: 2022

Includes: Supplemental data

Journal Articles

Evolutionary Action Score Identifies a Subset of TP53 Mutated Myelodysplastic Syndrome with Favorable Prognosis

Blood (2020) 136 (Supplement 1): 4–5.

https://doi.org/10.1182/blood-2020-141411

Published: 2020

Journal Articles

Only Hotspot SF3B1 K700E Mutation Is an Independent Predictor of Overall Survival in Myelodysplastic Syndromes

Rashmi Kanagal-Shamanna, MD, Guillermo Montalban Bravo, MD, Koji Sasaki, MD, Carlos E. Bueso-Ramos, MD PhD, Elias Jabbour, MD, Yue Wei, PhD, Faezeh Darbaniyan, PhD, Mark Routbort, MD PhD, Sherry A. Pierce, BSN, BA, Kelly A. Soltysiak, PhD, Keyur Patel, MD PhD, L. Jeffrey Medeiros, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2020) 136 (Supplement 1): 24–25.

https://doi.org/10.1182/blood-2020-141446

Published: 2020

Journal Articles

Evolutionary Action (EA) Score of TP53 Mutations Defines Prognostic Subsets within TP53 Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia

Rashmi Kanagal-Shamanna, MD, Guillermo Montalban-Bravo, MD, Caleb Class, PhD, Koji Sasaki, MD, Christopher B. Benton, MD, Kelly Soltysiak, PhD, Elias Jabbour, MD, Tapan M. Kadia, MD, Carlos E. Bueso-Ramos, MD PhD, Keyur P. Patel, MBBS, PhD, Mark Routbort, MD PhD, Irene Ganan-Gomez, PhD, Yue Wei, PhD, Gautam M. Borthakur, MD, Farhad Ravandi, MD, Kim-Anh Do, PhD, L. Jeffrey Medeiros, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2019) 134 (Supplement_1): 1719.

https://doi.org/10.1182/blood-2019-130545

Published: 2019

Journal Articles

The Impact of PHF6 Mutations in Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, and Acute Myeloid Leukemia

Kelly S. Chien, MD, Rashmi Kanagal-Shamanna, MD, Kiran Naqvi, MDMPH, Koji Sasaki, MD, Yesid Alvarado, MD, Koichi Takahashi, MD, Tapan M. Kadia, MD, Gautam M. Borthakur, MD, Elias Jabbour, MD, Mark Routbort, MD PhD, Sherry A. Pierce, BSN, BA, Kelly Soltysiak, PhD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD, Guillermo Montalban-Bravo, MD

Blood (2019) 134 (Supplement_1): 1436.

https://doi.org/10.1182/blood-2019-131188

Published: 2019

Journal Articles

Next-Generation Sequencing of DDX41 in Myeloid Neoplasms Leads to Increased Detection of Germline Alterations

Sarah Bannon, MS, CGC, Mark Routbort, MD PhD, Guillermo Garcia-Manero, MD, Naval G. Daver, MD, Betul Oran, MD MS, Gautam Borthakur, MD, Rohtesh S. Mehta, MD MPH,MS, Kiran Naqvi, MD MPH, Koichi Takahashi, MD, Yesid Alvarado, MD, Tapan M. Kadia, MD, Hagop M. Kantarjian, MD, Keyur P. Patel, MBBS, PhD, Courtney D. DiNardo, MD MSc

Blood (2018) 132 (Supplement 1): 2667.

https://doi.org/10.1182/blood-2018-99-116518

Published: 2018

Journal Articles

Myeloid Malignancy Variant Curation Expert Panel: An ASH-Sponsored Clingen Expert Panel to Optimize and Validate Acmg/AMP Variant Interpretation Guidelines for Genes Associated with Inherited Myeloid Neoplasms

Blood (2018) 132 (Supplement 1): 5849.

https://doi.org/10.1182/blood-2018-99-118979

Published: 2018

Journal Articles

RAS and TP53 , Not NOTCH1 , Can Predict Survival in Adults with Acute T-Cell Lymphoblastic Leukemia Treated with Hypercvad

Ali Sakhdari, MD MSc, Sanam Loghavi, MD, Rashmi Kanagal-Shamanna, MD, C. Cameron Yin, MD PhD, Zhuang Zuo, MD, Mark Routbort, MD PhD, Keyur P. Patel, MBBS, PhD, Raja Luthra, PhD, L. Jeffrey Medeiros, MD, Chi Young Ok, MD

Blood (2018) 132 (Supplement 1): 4085.

https://doi.org/10.1182/blood-2018-99-119017

Published: 2018

Journal Articles

Endleukemia Assay v1: Enabling NGS-Based Comprehensive Routine Molecular Profiling of Leukemias in Routine Clinical Care

Chi Young Ok, MD, Rajesh Singh, PhD, Rajyalakshmi Luthra, PhD, David Hatfield, Kristen Floyd, Sanam Loghavi, MD, Rashmi Kanagal-Shamanna, MD, Zhuang Zuo, C. Cameron Yin, MD PhD, Mark Routbort, MD PhD, Hagop M. Kantarjian, MD, L. Jeffrey Medeiros, MD, Keyur P. Patel, MBBS, PhD

Blood (2017) 130 (Supplement 1): 2679.

https://doi.org/10.1182/blood.V130.Suppl_1.2679.2679

Published: 2017

Journal Articles

Standardized Targeted Sequencing of 29 Genes with Recurrent Mutations in Chronic Lymphocytic Leukemia (CLL) Helps to Better Define Clinical Correlates and Genomic Hotspots

Blood (2017) 130 (Supplement 1): 4304.

https://doi.org/10.1182/blood.V130.Suppl_1.4304.4304

Published: 2017

Journal Articles

Value of Immunohistochemistry-Based Direct Visualization for Localization, Lineage Determination and Monitoring of IDH1 p.R132H Mutant Clones in AML

Habibe Kurt, MD, Carlos E. Bueso-Ramos, MD PhD, Joseph D Khoury, MD, Mark Routbort, MD PhD, Rashmi Kanagal-Shamanna, MD, Jeffrey L. Jorgensen, MD PhD, Courtney D DiNardo, MD, Farhad Ravandi, MD, Hagop M. Kantarjian, MD, Raja Luthra, PhD, Jeffrey Medeiros, MD, Keyur Patel, MD

Blood (2016) 128 (22): 1726.

https://doi.org/10.1182/blood.V128.22.1726.1726

Published: 2016

Journal Articles

Routine Clinical Testing for Actionable Mutations in CLL Using Endcll Assay V1: The Initial MD Anderson Experience

Keyur P. Patel, MD PhD, Rajesh Singh, PhD, Mark Routbort, MD PhD, C. Cameron Yin, MD PhD, Rashmi Kanagal Shamanna, PhD, Nitin Jain, MD, Xinyan Lu, MD, Sherry Pierce, BSN, BA, Michael Keating, MBBS, Hagop M. Kantarjian, MD, L. Jeffrey Medeiros, MD, Raja Luthra, PhD, William G. Wierda, MD PhD

Blood (2016) 128 (22): 3196.

https://doi.org/10.1182/blood.V128.22.3196.3196

Published: 2016

NARROW

BRAF -Mutated Acute Myeloid Leukemia (AML) Represents a Prognostically Poor Subgroup Enriched for Myelodysplasia-Related Subtypes and Distinct from Other RAS Pathway Mutant AML

Genomic Profiling of T-Cell Acute Lymphoblastic Leukemia/Lymphoma (T-ALL) for Identification of Driver Aberrations Using Combined Next Generation Sequencing and Optical Genome Mapping in Clinical Diagnostic Laboratory

BRAF -Mutated Acute Myeloid Leukemia (AML) Represents a Distinct, Prognostically Poor Subgroup Enriched in Myelodysplasia-Related (MR-)AML

Clinical and Prognostic Implications of WT1 Mutations in De Novo and Relapsed Acute Myeloid Leukemia

Mutation Spectrum, Characteristics and Impact of Mutation Profiling on Prognosis, Outcome and Treatment Responses in Patients (pts) with Mantle Cell Lymphoma

The Adverse Effect of Myelodysplasia-Related Mutations in De Novo Acute Myeloid Leukemia Is Associated with Higher Variant Allelic Frequency (VAF): A Proposal for a Numeric Cutoff for Variant Allelic Frequency

Clinical and Molecular Characterization of Newly Diagnosed IDH/TP53 Co-Mutated AML and Impact of Genomically Sensitive Treatment Strategies

Homologous Recombination DNA Repair Deficiency Score Is Independent Prognostic Variable in Myelodysplastic Syndrome/ Acute Myeloid Leukemia with Complex Karyotype

TP53 copy number and protein expression inform mutation status across risk categories in acute myeloid leukemia

Evolutionary Action Score Identifies a Subset of TP53 Mutated Myelodysplastic Syndrome with Favorable Prognosis

Only Hotspot SF3B1 K700E Mutation Is an Independent Predictor of Overall Survival in Myelodysplastic Syndromes

Evolutionary Action (EA) Score of TP53 Mutations Defines Prognostic Subsets within TP53 Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia

The Impact of PHF6 Mutations in Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, and Acute Myeloid Leukemia

Next-Generation Sequencing of DDX41 in Myeloid Neoplasms Leads to Increased Detection of Germline Alterations

Myeloid Malignancy Variant Curation Expert Panel: An ASH-Sponsored Clingen Expert Panel to Optimize and Validate Acmg/AMP Variant Interpretation Guidelines for Genes Associated with Inherited Myeloid Neoplasms

RAS and TP53 , Not NOTCH1 , Can Predict Survival in Adults with Acute T-Cell Lymphoblastic Leukemia Treated with Hypercvad

Endleukemia Assay v1: Enabling NGS-Based Comprehensive Routine Molecular Profiling of Leukemias in Routine Clinical Care

Standardized Targeted Sequencing of 29 Genes with Recurrent Mutations in Chronic Lymphocytic Leukemia (CLL) Helps to Better Define Clinical Correlates and Genomic Hotspots

Value of Immunohistochemistry-Based Direct Visualization for Localization, Lineage Determination and Monitoring of IDH1 p.R132H Mutant Clones in AML

Routine Clinical Testing for Actionable Mutations in CLL Using Endcll Assay V1: The Initial MD Anderson Experience

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