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Journal Articles

Exploiting RAS pathway addiction as a therapeutic vulnerability in myeloid sarcoma

Blood (2025) 146 (Supplement 1): 220.

https://doi.org/10.1182/blood-2025-220

Published: 2025

Journal Articles

Non-coding variants in UBA1 lead to vexas

Maria Sirenko, Flore Castellan, Samuel Magaziner, Deborah Hernandez, Matthew J Koster, Olivier Kosmider, Iannis Aifantis, Achim Werner, David Beck

Blood (2025) 146 (Supplement 1): 30.

https://doi.org/10.1182/blood-2025-30

Published: 2025

Journal Articles

Epigenetic reactivation of a tumor suppressor program in AML.

Eric Wang, Cuijuan Han, Alexander Arnuk, Iannis Aifantis, Hussein Abbas, Aristotelis Tsirigos, Sadik Karma, Sakthi Harini Rajendran

Blood (2025) 146 (Supplement 1): 5000.

https://doi.org/10.1182/blood-2025-5000

Published: 2025

Journal Articles

CRISPR-Cas13d functional transcriptomics reveals widespread isoform-selective cancer dependencies on lncRNAs

Blood (2025) 146 (7): 847–860.

https://doi.org/10.1182/blood.2025028746

Published: 2025

Includes: Supplemental data

Journal Articles

Vitamin C deprivation puts stem cells to sleep

Juan Carlos Balandrán, Iannis Aifantis

Blood (2025) 145 (1): 7–8.

https://doi.org/10.1182/blood.2024026887

Published: 2025

Journal Articles

Isoform-Level Long Noncoding RNA Dependencies in Multiple Myeloma

Eugenio Morelli, Anil Aktas-Samur, Domenico Maisano, Claire Gao, Vanessa Favasuli, Dimitrios Papaioannou, Na Liu, Marcello Turi, Pietro Folino, Laure Vreux, Michela Cumerlato, Liang Cheng, Iannis Aifantis, Mariateresa Fulciniti, Kenneth C. Anderson, Annamaria Gulla, Mehmet K. Samur, Nikhil C. Munshi

Blood (2024) 144 (Supplement 1): 4130.

https://doi.org/10.1182/blood-2024-209546

Published: 2024

Journal Articles

Transcriptional Regulation of Cytotoxic T-Cell Responses in Acute Myeloid Leukemia

Xufeng Chen, Zhengxi Sun, Jana Elegast, Hua Zhou, Soobeom Lee, Deedra Nicolet, Qiao Lu, Kun Wang, Jun Wang, Wafa Al-Santli, Ann-Kathrin Eisfeld, Kimberly Stegmaier, Iannis Aifantis, Rebecca Austin

Blood (2024) 144 (Supplement 1): 5733.

https://doi.org/10.1182/blood-2024-193591

Published: 2024

Journal Articles

PAX5 Loss Compromises CD22 Protein Levels and Responses to Inotuzumab Ozogamicin in B-Cell Acute Lymphoblastic Leukemia

Jacinta Davis, JuanCarlos Balandrán, Katharina Hayer, Sisi Zheng, Zhiwei Ang, Evelyn Liu, Bonnie Yates, Nirali N. Shah, Iannis Aifantis, Andrei Thomas-Tikhonenko

Blood (2024) 144 (Supplement 1): 4170.

https://doi.org/10.1182/blood-2024-208185

Published: 2024

Journal Articles

Enhancing Macrophage Mediated Phagocytosis in AML: The Complementary Mechanisms of Venetoclax and Azacitidine Combination Therapy

Zhe WANG, Xufeng Chen, Simone Sidoli, Anna Skwarska, Yannan Jia, Lei Yang, Varun Gupta, Shikhar Sharma, Iannis Aifantis, Hussein A. Abbas, Naval Daver, Qi Zhang Tatarata, Marina Konopleva

Blood (2024) 144 (Supplement 1): 207.

https://doi.org/10.1182/blood-2024-198057

Published: 2024

Journal Articles

A Protein-Coding Circular RNA That Regulates DNA Damage Response in BCR :: ABL -Positive Leukemias

Amog Urs, Dimitrios Papaioannou, Rohan Kulkarni, Chinmayee Goda, Remi Buisson, Deedra Nicolet, Lauren Woodward, Krzysztof Mrózek, Gregory K Behbehani, Sakari Kauppinen, Ann-Kathrin Eisfeld, Iannis Aifantis, Guramrit Singh, Adrienne M. Dorrance, Ramiro Garzon

Blood (2024) 144 (Supplement 1): 954.

https://doi.org/10.1182/blood-2024-208650

Published: 2024

Journal Articles

CRISPR/ Rfx Cas13d Screening Identifies the Long Non-Coding RNA (LncRNA) Nfyc-AS1 As a Molecular Vulnerability in Acute Myeloid Leukemia (AML)

Dimitrios Papaioannou, Giovanni Gambi, Palaniraja Thandapani, Deedra Nicolet, Ziyan Lin, Krzysztof Mrózek, Olha Ivashkiv, Maria Sirenko, Bettina Nadorp, Ann-Kathrin Eisfeld, Aristotelis Tsirigos, Iannis Aifantis

Blood (2024) 144 (Supplement 1): 951.

https://doi.org/10.1182/blood-2024-203707

Published: 2024

Journal Articles

Deconvoluting Clonal and Cellular Architecture in IDH -Mutant Acute Myeloid Leukemia

Blood (2023) 142 (Supplement 1): 1591.

https://doi.org/10.1182/blood-2023-186322

Published: 2023

Journal Articles

The Genomic and Transcriptomic Landscape of Myeloid Sarcoma and Associated Acute Myeloid Leukemia

Blood (2023) 142 (Supplement 1): 292.

https://doi.org/10.1182/blood-2023-182967

Published: 2023

Journal Articles

Clinical and Prognostic Implications of WT1 Mutations in De Novo and Relapsed Acute Myeloid Leukemia

Blood (2023) 142 (Supplement 1): 959.

https://doi.org/10.1182/blood-2023-188319

Published: 2023

Journal Articles

Stroma-Driven Notch2 Signaling Controls Naïve B Cell Fate By Regulating Microenvironmental Positioning within the Spleen

Blood (2023) 142 (Supplement 1): 2549.

https://doi.org/10.1182/blood-2023-186941

Published: 2023

Journal Articles

High ORM1 Expression Marks a Subset of Genetically Adverse-Risk B-ALL Characterized By MDSC Enrichment, T-Cell Dysfunction, and Inferior Overall Survival

Matthew M Klairmont, William L. Carroll, Iannis Aifantis, Christopher Y. Park

Blood (2022) 140 (Supplement 1): 6360.

https://doi.org/10.1182/blood-2022-169402

Published: 2022

Journal Articles

Modulation of RNA Splicing Enhances Response to BCL2 Inhibition in Acute Myeloid Leukemia

Eric Wang, Jose Mario Bello Pineda, Jessie Bourcier, Maximilian Stahl, Alexander V Penson, Isaac Wakiro, Michael E Singer, Daniel Cui, Caroline Erickson, Katherine Knorr, Robert Stanley, Xufeng Chen, Elizabeth A. McMillan, Carine Bossard, Iannis Aifantis, Robert K. Bradley, Omar Abdel-Wahab

Blood (2021) 138 (Supplement 1): 507.

https://doi.org/10.1182/blood-2021-146373

Published: 2021

Journal Articles

Non-Classical Monocyte Abundance Is an Independent Adverse Risk Factor for Relapse in Pediatric B-ALL

Gloria Paz Contreras Yametti, Nikki Ann Evensen, Meenakshi Devidas, Elizabeth A. Raetz, Karen R Rabin, David T. Teachey, Iannis Aifantis, William L. Carroll, Matthew Witkowski

Blood (2021) 138 (Supplement 1): 1316.

https://doi.org/10.1182/blood-2021-146918

Published: 2021

Journal Articles

Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion

Blood (2020) 135 (2): 108–120.

https://doi.org/10.1182/blood.2019001438

Published: 2020

Includes: Supplemental data

Journal Articles

Innate Immune Signaling Suppresses Acute Leukemia By Modifying MYC Oncogenic Activity

Tomoya Muto, MD PhD, Maria Guillamot, PhD, Jing Fang, MD PhD, Luna Zea Redondo, MS, Kwangmin Choi, PhD, Yixiao Gong, MSc, Callum S Walker, MSc, Kathleen Hueneman, Lyndsey C Bolanos, BSc, Laura Barreyro, PhD, Lynn Lee, MD, Kenneth D Greis, PhD, Alireza Khodadadi-Jamayran, M.Sc., Amaia Lujambio, PhD, Scott W. Lowe, PhD, Iannis Aifantis, PhD, Daniel T. Starczynowski, PhD

Blood (2019) 134 (Supplement_1): 727.

https://doi.org/10.1182/blood-2019-121423

Published: 2019

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Exploiting RAS pathway addiction as a therapeutic vulnerability in myeloid sarcoma

Non-coding variants in UBA1 lead to vexas

Epigenetic reactivation of a tumor suppressor program in AML.

CRISPR-Cas13d functional transcriptomics reveals widespread isoform-selective cancer dependencies on lncRNAs

Vitamin C deprivation puts stem cells to sleep

Isoform-Level Long Noncoding RNA Dependencies in Multiple Myeloma

Transcriptional Regulation of Cytotoxic T-Cell Responses in Acute Myeloid Leukemia

PAX5 Loss Compromises CD22 Protein Levels and Responses to Inotuzumab Ozogamicin in B-Cell Acute Lymphoblastic Leukemia

Enhancing Macrophage Mediated Phagocytosis in AML: The Complementary Mechanisms of Venetoclax and Azacitidine Combination Therapy

A Protein-Coding Circular RNA That Regulates DNA Damage Response in BCR :: ABL -Positive Leukemias

CRISPR/ Rfx Cas13d Screening Identifies the Long Non-Coding RNA (LncRNA) Nfyc-AS1 As a Molecular Vulnerability in Acute Myeloid Leukemia (AML)

Deconvoluting Clonal and Cellular Architecture in IDH -Mutant Acute Myeloid Leukemia

The Genomic and Transcriptomic Landscape of Myeloid Sarcoma and Associated Acute Myeloid Leukemia

Clinical and Prognostic Implications of WT1 Mutations in De Novo and Relapsed Acute Myeloid Leukemia

Stroma-Driven Notch2 Signaling Controls Naïve B Cell Fate By Regulating Microenvironmental Positioning within the Spleen

High ORM1 Expression Marks a Subset of Genetically Adverse-Risk B-ALL Characterized By MDSC Enrichment, T-Cell Dysfunction, and Inferior Overall Survival

Modulation of RNA Splicing Enhances Response to BCL2 Inhibition in Acute Myeloid Leukemia

Non-Classical Monocyte Abundance Is an Independent Adverse Risk Factor for Relapse in Pediatric B-ALL

Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion

Innate Immune Signaling Suppresses Acute Leukemia By Modifying MYC Oncogenic Activity

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American Society of Hematology

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