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Journal Articles

SF3B1 Mutation Drives Loss of Y Chromosome in Chronic Lymphocytic Leukemia

Mike Fernandez, Lei Yu, Qiong Jia, Xuesong Wang, Kevyn Hart, Zhenyu Jia, Ren-Jang Lin, Lili Wang

Blood (2024) 144 (Supplement 1): 46.

https://doi.org/10.1182/blood-2024-208209

Published: 2024

Journal Articles

Integrating Metabolomics and Molecular Pathways to Uncover Therapeutic Vulnerabilities in Richter's Transformation

Prajish Iyer, Brian Jiang, Girish Venkataraman, Joo Y. Song, Wing Chung Chan, Tanya Siddiqi, Steven T. Rosen, Alexey Danilov, Antje Gohla, Lili Wang

Blood (2024) 144 (Supplement 1): 760.

https://doi.org/10.1182/blood-2024-199843

Published: 2024

Journal Articles

Impaired Response to Oxidative DNA Damage Underlies Genomic Instability in B-Cell Leukemia Driven By RPS15 Mutation

Blood (2024) 144 (Supplement 1): 758.

https://doi.org/10.1182/blood-2024-202115

Published: 2024

Journal Articles

Multiomic Discovery of Neopeptides from Non-Canonical ORFs on SF3B1 Mutation-Driven lncRNAs in Leukemia

Supriyo Bhattacharya, Mike Fernandez, Yiming Wu, Meiling Jin, Lili Wang

Blood (2024) 144 (Supplement 1): 1061.

https://doi.org/10.1182/blood-2024-208361

Published: 2024

Journal Articles

Final Update of Safety, Efficacy and T-Cell Predictive Biomarkers from a Phase I Trial of Copanlisib+Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Geoffrey Shouse, Leslie Popplewell, Alex Muir, Tanya Siddiqi, Jasmine Zain, Alex F. Herrera, Olga Danilova, Stephen E Spurgeon, Lili Wang, Adam S Kittai, Lu Chen, Matthew S. Davids, Alexey V. Danilov

Blood (2024) 144 (Supplement 1): 4484.

https://doi.org/10.1182/blood-2024-209610

Published: 2024

Journal Articles

Proteogenomic Features Define Novel Subtypes of Mantle Cell Lymphoma

Yuting Yan, Xinzhou Ge, Jian Sun, Lei Yu, Qunling Zhang, Ying Yu, Zhenyu Jia, Dehui Zou, Jessica Li, Lugui Qiu, Lili Wang, Shuhua Yi

Blood (2023) 142 (Supplement 1): 4368.

https://doi.org/10.1182/blood-2023-190838

Published: 2023

Journal Articles

RNA Splicing Factor Mutations Drive Aberrant Canonical and Cryptic Circular RNA Biogenesis in Leukemia

Mike Fernandez, Meiling Jin, Qiong Jia, Yiming Wu, Kevyn Hart, Emilee Bargoma, Joseph Pangallo, Robert K. Bradley, Omar Abdel-Wahab, Zhenyu Jia, Ren-Jang Lin, Lili Wang

Blood (2023) 142 (Supplement 1): 1395.

https://doi.org/10.1182/blood-2023-174135

Published: 2023

Journal Articles

Glycerolipid Metabolism Via the MGA-MYC-NME1-PGP Axis As a Key Regulator of Oxidative Phosphorylation in Richter's Transformation

Prajish Iyer, Brian Jiang, Girish Venkataraman, Joo Y Song, Tanya Siddiqi, Steven T. Rosen, Alexey Danilov, Lili Wang

Blood (2023) 142 (Supplement 1): 79.

https://doi.org/10.1182/blood-2023-179427

Published: 2023

Journal Articles

Safety, Efficacy and T-Cell Predictive Biomarkers in a Phase I Trial of Copanlisib+Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Geoffrey P. Shouse, Leslie L. Popplewell, Alex Muir, Tanya Siddiqi, Alex F. Herrera, Olga Danilova, Sandrine Puverel, Lili Wang, Adam S Kittai, Lu Chen, Matthew S Davids, Alexey Danilov

Blood (2023) 142 (Supplement 1): 1730.

https://doi.org/10.1182/blood-2023-182559

Published: 2023

Journal Articles

Beyond CLL Progression: Unveiling Th17 and Th2 T Cell Subsets As Predictors of Pembrolizumab Response in Richter's Transformation

Prajish Iyer, Lu Yang, Sutapa Sinha, Miles Del Busso, Zhi-Zhang Yang, Hyojin Kim, Charla Secreto, Yucai Wang, Neil E. Kay, Stephen M Ansell, Wei Ding, Lili Wang

Blood (2023) 142 (Supplement 1): 1888.

https://doi.org/10.1182/blood-2023-181004

Published: 2023

Journal Articles

A Phase I Trial of PI3Kαδ Inhibitor Copanlisib in Combination with Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Geoffrey Shouse, Tanya Siddiqi, Leslie L. Popplewell, Alexandra Muir, Ivana Melgar, Kirsten Orand, Brandy Gonzalez, Sandrine Puverel, Lili Wang, Adam S Kittai, Lu Chen, Matthew S. Davids, Alexey V Danilov

Blood (2022) 140 (Supplement 1): 6633–6634.

https://doi.org/10.1182/blood-2022-160157

Published: 2022

Journal Articles

Disrupting MGA-MYC Driven Metabolic Reprogramming in Richter's Syndrome Pre-Clinical Models Via Novel Therapeutic Approaches

Prajish Iyer, Bo Zhang, Tingting Liu, Meiling Jin, Kevyn Hart, Joo Y. Song, Wing C Chan, Tanya Siddiqi, Alexey V Danilov, Steve T Rosen, Lili Wang

Blood (2022) 140 (Supplement 1): 9842–9843.

https://doi.org/10.1182/blood-2022-162664

Published: 2022

Journal Articles

Individualized Dosing of Anti-Thymocyte Globulin Led to Reduced CMV/EBV Reactivation and Superior Overall Survival in Adult Unmanipulated Haploidentical Peripheral Blood Stem Cell Transplantation: A Prospective Phase II Study

Haitao Wang, Liping Dou, Lili Wang, Bo Peng, Nan Wang, Yingxin Zhao, Jishan Du, Daihong Liu

Blood (2022) 140 (Supplement 1): 4753–4754.

https://doi.org/10.1182/blood-2022-158994

Published: 2022

Journal Articles

MGA deletion Leads to Richter's Transformation Via NME1

Prajish Iyer, Bo Zhang, Tingting Liu, Meiling Jin, Kevyn Hart, Joo Y. Song, John Chan, Raju Pillai, Tanya Siddiqi, Alexey V. Danilov, Steven T. Rosen, Lili Wang

Blood (2021) 138 (Supplement 1): 252.

https://doi.org/10.1182/blood-2021-148953

Published: 2021

Journal Articles

B Cell-Restricted Depletion of Dnmt3a Activates Notch Signaling and Causes Chronic Lymphocytic Leukemia

Blood (2021) 138 (Supplement 1): 249.

https://doi.org/10.1182/blood-2021-150789

Published: 2021

Journal Articles

METTL3 Dysregulates RNA Splicing by Translational Control of Splicing Factors via m 6 A Modification in CLL

Yiming Wu, Meiling Jin, Mike Fernandez, Kevyn Hart, Aijun Liao, Stacey M. Fernandes, Tinisha McDonald, Lucy Ghoda, Daniel Roeth, Markus Kalkum, Raju Pillai, Jianjun Chen, Jennifer R Brown, Alexey V. Danilov, Steven T. Rosen, Tanya Siddiqi, Lili Wang

Blood (2021) 138 (Supplement 1): 499.

https://doi.org/10.1182/blood-2021-149691

Published: 2021

Journal Articles

Nedd8-Activating Enzyme Inhibition Enhances Anti-Tumor Immunity and PD1 Blockade in In Vivo lymphoma Models

Xiaoguang Wang, Vi Lam, Dan Vuong, Tingting Liu, Olga Danilova, Tanya Siddiqi, Allison J Berger, Lili Wang, Alexey V. Danilov

Blood (2021) 138 (Supplement 1): 2414.

https://doi.org/10.1182/blood-2021-146349

Published: 2021

Journal Articles

Richter's Transformation after CD-19 Directed CAR-T Cells for Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)

Amanda Blackmon, Alexey V. Danilov, Lili Wang, Raju Pillai, Hormoz Babaei Mirshkarlo, Steven T. Rosen, Tanya Siddiqi

Blood (2021) 138 (Supplement 1): 1430.

https://doi.org/10.1182/blood-2021-149815

Published: 2021

Journal Articles

A Phase I Trial of PI3Kαδ Inhibitor Copanlisib in Combination with Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Geoffrey Shouse, Tanya Siddiqi, Leslie L. Popplewell, Alexandra Muir, Ivana Melgar, Brandy Gonzales, Kirsten Orand, Sandrine Puverel, Lili Wang, Adam S Kittai, Lu Chen, Matthew S. Davids, Alexey V. Danilov

Blood (2021) 138 (Supplement 1): 3558.

https://doi.org/10.1182/blood-2021-149320

Published: 2021

Journal Articles

R-Loop Associated Mitotic Stress Confers Vulnerabilities in Splicing Factor Mutant Leukemia

Martina Cusan, Meiling Jin, Bo Zhang, Mike Fernandez, Aijun Liao, Lu Yang, Yiming Wu, Prajish Iyer, Kevyn Hart, Catherine Gutierrez, Jeremy Stark, Teresa V. Bowman, Catherine J. Wu, Ren-Jang Lin, Lili Wang

Blood (2021) 138 (Supplement 1): 3713.

https://doi.org/10.1182/blood-2021-151298

Published: 2021

NARROW

SF3B1 Mutation Drives Loss of Y Chromosome in Chronic Lymphocytic Leukemia

Integrating Metabolomics and Molecular Pathways to Uncover Therapeutic Vulnerabilities in Richter's Transformation

Impaired Response to Oxidative DNA Damage Underlies Genomic Instability in B-Cell Leukemia Driven By RPS15 Mutation

Multiomic Discovery of Neopeptides from Non-Canonical ORFs on SF3B1 Mutation-Driven lncRNAs in Leukemia

Final Update of Safety, Efficacy and T-Cell Predictive Biomarkers from a Phase I Trial of Copanlisib+Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Proteogenomic Features Define Novel Subtypes of Mantle Cell Lymphoma

RNA Splicing Factor Mutations Drive Aberrant Canonical and Cryptic Circular RNA Biogenesis in Leukemia

Glycerolipid Metabolism Via the MGA-MYC-NME1-PGP Axis As a Key Regulator of Oxidative Phosphorylation in Richter's Transformation

Safety, Efficacy and T-Cell Predictive Biomarkers in a Phase I Trial of Copanlisib+Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Beyond CLL Progression: Unveiling Th17 and Th2 T Cell Subsets As Predictors of Pembrolizumab Response in Richter's Transformation

A Phase I Trial of PI3Kαδ Inhibitor Copanlisib in Combination with Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Disrupting MGA-MYC Driven Metabolic Reprogramming in Richter's Syndrome Pre-Clinical Models Via Novel Therapeutic Approaches

Individualized Dosing of Anti-Thymocyte Globulin Led to Reduced CMV/EBV Reactivation and Superior Overall Survival in Adult Unmanipulated Haploidentical Peripheral Blood Stem Cell Transplantation: A Prospective Phase II Study

MGA deletion Leads to Richter's Transformation Via NME1

B Cell-Restricted Depletion of Dnmt3a Activates Notch Signaling and Causes Chronic Lymphocytic Leukemia

METTL3 Dysregulates RNA Splicing by Translational Control of Splicing Factors via m 6 A Modification in CLL

Nedd8-Activating Enzyme Inhibition Enhances Anti-Tumor Immunity and PD1 Blockade in In Vivo lymphoma Models

Richter's Transformation after CD-19 Directed CAR-T Cells for Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)

A Phase I Trial of PI3Kαδ Inhibitor Copanlisib in Combination with Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

R-Loop Associated Mitotic Stress Confers Vulnerabilities in Splicing Factor Mutant Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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