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Journal Articles

The LSD1 Inhibitor RN1 Rescues Congenital Dyserythropoietic Anemia Type II

Lei Yu, Yu Wang, Richard King, Greggory Myers, Beth McGee, Ann Friedman, Ginette Balbin-Cuesta, Zesen Lin, Claire Drysdale, Xiaofang Liu, Claire Kerpet, Kaiwen Deng, Aaron Robida, James Engel, Rami Khoriaty

Blood (2024) 144 (Supplement 1): 938.

https://doi.org/10.1182/blood-2024-201649

Published: 2024

Journal Articles

Sequential Infusion of Anti-CD19 and Anti-BCMA Chimeric Antigen Receptor T-Cells: A Promising Treatment Strategy for Refractory Immune-Mediated Platelet Transfusion Refractoriness

Yunju Ma, Qingya Cui, Chunxiu Yang, Wei Cui, Mengyun Li, Zheng Li, Haiping Dai, Liqing Kang, Lei Yu, Zaixiang Tang, Jianxin Fu, Min Jiang, Depei Wu, Xiaowen Tang

Blood (2024) 144 (Supplement 1): 683.

https://doi.org/10.1182/blood-2024-209249

Published: 2024

Journal Articles

SF3B1 Mutation Drives Loss of Y Chromosome in Chronic Lymphocytic Leukemia

Mike Fernandez, Lei Yu, Qiong Jia, Xuesong Wang, Kevyn Hart, Zhenyu Jia, Ren-Jang Lin, Lili Wang

Blood (2024) 144 (Supplement 1): 46.

https://doi.org/10.1182/blood-2024-208209

Published: 2024

Journal Articles

Long-Term Remission and Survival in Patients with Rituximab-Refractory/Relapsed B-Cell Non-Hodgkin Lymphoma after Treatment with U16 (CD20 CAR-T cells)

Qian Cheng, JingWen Tan, Rui Liu, Liqing Kang, Hongjia Zhu, Yi Zhang, Erhua Wang, Ying Li, Jian Zhang, Han Xiao, Rong He, Xiaoyan Lou, Nan Xu, Wei Wang, Zhou Yu, Minghao Li, Hongfei Gu, Lei Yu, Xin Li

Blood (2024) 144 (Supplement 1): 3447.

https://doi.org/10.1182/blood-2024-200516

Published: 2024

Journal Articles

Target Antigen-Expressing T Cells Facilitate CAR-T Cell Eradication of Residual CD19+ B Malignant Cells

Blood (2024) 144 (Supplement 1): 4794.

https://doi.org/10.1182/blood-2024-206406

Published: 2024

Journal Articles

Chemotherapy-Free Induction with Venetoclax and Azacitidine, Followed By Tandem CD19/CD22 CAR-T Cell Therapy As First-Line Treatment in Newly Diagnosed High-Risk Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia: A Prospective, Single-Center, Single-Arm, Phase 2 Trial

Mengyun Li, Qingya Cui, Xuekai Li, Wei Cui, Xiaoqian Chen, Yan Yu, Juan Chen, Xin Zhang, Liqing Kang, Lei Yu, Depei Wu, Xiaowen Tang

Blood (2024) 144 (Supplement 1): 4197.

https://doi.org/10.1182/blood-2024-207017

Published: 2024

Journal Articles

Safety and Efficacy of CD22/ CD19 CAR-T and Auto-HSCT “Sandwich”Strategy As Consolidation Therapy for Ph Negative B Cell Acute Lymphoblastic Leukemia

Zihao Wang, Chong-Sheng Qian, Yan Qiu, Hai-xia Zhou, Mingzhu Xu, Li-Qing Kang, Ai-Ning Sun, Depei Wu, Lei Yu, Sheng-Li Xue

Blood (2024) 144 (Supplement 1): 4840.

https://doi.org/10.1182/blood-2024-204636

Published: 2024

Journal Articles

Unleashing the Power of CD19 CAR-T in Relapsed AML: Findings from a Prospective Single-Center Clinical Trial

Jia Yin, Qingya Cui, Haiping Dai, Zheng Li, Liqing Kang, Wei Cui, Xiaopeng Tian, Xiaming Zhu, Lei Yu, Depei Wu, Xiaowen Tang

Blood (2024) 144 (Supplement 1): 4836.

https://doi.org/10.1182/blood-2024-207197

Published: 2024

Journal Articles

Bird Regimen Followed By Anti-BCMA CAR T-Cell Immunotherapy As First-Line Therapy for Newly Diagnosed Multiple Myeloma: A Prospective, Single-Arm, Phase 3 Trial

Yue Zhou, Juan Chen, Qingya Cui, Haiping Dai, Zheng Li, Jia Yin, Wei Cui, Mengyun Li, Xuekai Li, Xin Zhang, Feiran Gong, Xiaming Zhu, Liqing Kang, Lei Yu, Depei Wu, Xiaowen Tang

Blood (2024) 144 (Supplement 1): 3384.

https://doi.org/10.1182/blood-2024-199119

Published: 2024

Journal Articles

5-Year Follow-up of Combined Infusion of Anti-CD19 and Anti-BCMA CAR-T after ASCT for High-Risk Newly Diagnosed Multiple Myeloma

Xiaolan Shi, Chengcheng Fu, Lingzhi Yan, Yingying Zhai, Zhi Yan, Jingjing Shang, Song Jin, Xingyue Wu, Hongying You, Shuang Yan, Weiqin Yao, Liqing Kang, Lei Yu, Depei Wu

Blood (2024) 144 (Supplement 1): 4766.

https://doi.org/10.1182/blood-2024-207687

Published: 2024

Journal Articles

TR4 and BCL11A Repress γ-globin Transcription via Independent Mechanisms

Yu Wang, Greggory Myers, Lei Yu, Kaiwen Deng, Ginette Balbin-Cuesta, Sharon A. Singh, Yuanfang Guan, Rami Khoriaty, James Douglas Engel

Blood blood.2024024599.

https://doi.org/10.1182/blood.2024024599

Published: 2024

Includes: Supplemental data

Journal Articles

Direct and Indirect Functions of TR4 in the Control of Fetal Hemoglobin Silencing

Yu Wang, Lei Yu, Greggory Myers, Sharon A Singh, James Engel

Blood (2023) 142 (Supplement 1): 555.

https://doi.org/10.1182/blood-2023-181113

Published: 2023

Journal Articles

Whole-Genome CRISPR-Cas9 Screening Identifies Genes Required for Human and Mouse Erythroid Development

Greggory Myers, Ann Friedman, Lei Yu, Claire Kerpet, Masaki Ito, Rilie Saba, Ginette Balbin-Cuesta, Zesen Lin, Claire Drysdale, Ayse Bilge Ozel, James Engel, Rami Khoriaty

Blood (2023) 142 (Supplement 1): 3828.

https://doi.org/10.1182/blood-2023-181929

Published: 2023

Journal Articles

The Clinical Outcome of Patients with Refractory/Relapsed Lymphoid Blastic Phase of Chronic Myeloid Leukemia Treated with CAR T-Cells Therapy

Yujie Liu, Yuqing Tu, Jinyan Xiao, Yifan Shen, Biqi Zhou, Qiannan Yang, Tianhui Liu, Lijuan Qi, Jia Chen, Lei Yu, Depei Wu, Xu Yang

Blood (2023) 142 (Supplement 1): 6913.

https://doi.org/10.1182/blood-2023-190741

Published: 2023

Journal Articles

Rituximab Improves Clinical Outcomes of CAR-T Therapy for r/r B-ALL Via Sensitizing Leukemia Cells to CAR-T-Mediated Cytotoxicity and Reducing CAR-T Exhaustion

Yangzi Li, Sining Liu, Qingya Cui, Lingling Liu, Zheng Li, Wei Cui, Mengyun Li, Xiaming Zhu, Liqing Kang, Lei Yu, Depei Wu, Xiaowen Tang

Blood (2023) 142 (Supplement 1): 6803.

https://doi.org/10.1182/blood-2023-184505

Published: 2023

Journal Articles

Identifying Novel Regulators of γ-Globin Expression Using a Genome-Scale CRISPR Activation Screen

Ginette Balbin-Cuesta, Greggory Myers, Zesen Lin, Claire Kerpet, Beth McGee, Katherine Rybkin, Richard King, Claire Drysdale, Ann Friedman, Lei Yu, Masaki Ito, Rilie Saba, Ayse Bilge Ozel, Rami Khoriaty

Blood (2023) 142 (Supplement 1): 1100.

https://doi.org/10.1182/blood-2023-182203

Published: 2023

Journal Articles

Safety and Efficacy of CD22/ CD19 CAR-T and Auto-HSCT “Sandwich” Strategy As Consolidation Therapy for Ph Negative B Cell Acute Lymphoblastic Leukemia

Yan Qiu, Chong-Sheng Qian, Hai-Xia Zhou, Ming-Zhu Xu, Li-Qing Kang, Ai-Ning Sun, De-Pei Wu, Lei Yu, Sheng-Li Xue

Blood (2023) 142 (Supplement 1): 3481.

https://doi.org/10.1182/blood-2023-182728

Published: 2023

Journal Articles

Proteogenomic Features Define Novel Subtypes of Mantle Cell Lymphoma

Yuting Yan, Xinzhou Ge, Jian Sun, Lei Yu, Qunling Zhang, Ying Yu, Zhenyu Jia, Dehui Zou, Jessica Li, Lugui Qiu, Lili Wang, Shuhua Yi

Blood (2023) 142 (Supplement 1): 4368.

https://doi.org/10.1182/blood-2023-190838

Published: 2023

Journal Articles

Whole-Genome CRISPR-Cas9 Screen Identifies ZBTB7A As a Potential Therapeutic Target for Cda-II

Lei Yu, Greggory Myers, Beth McGee, Xiaofang Liu, Gallagher Patrick, Richard King, Ann Friedman, Ginette Balbin-Cuesta, Zesen Lin, Claire Drysdale, Claire Kerpet, Singh Sharon, James Engel, Rami Khoriaty

Blood (2023) 142 (Supplement 1): 12.

https://doi.org/10.1182/blood-2023-182246

Published: 2023

Journal Articles

Phase I Open-Label Single-Arm Study of Sscart-19 in Adult Patients with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia in China

Liqing Kang, Shengli Xue, Xiaowen Tang, Xiaoyan Lou, Chongsheng Qian, Wenjie Gong, Mingzhu Xu, Haixia Zhou, Zhen Yao, Wei Wang, Minghao Li, Nan Xu, Zhou Yu, Suning Chen, Huiying Qiu, Haiping Dai, Yang Xu, Depei Wu, Lei Yu

Blood (2023) 142 (Supplement 1): 3477.

https://doi.org/10.1182/blood-2023-181552

Published: 2023

NARROW

The LSD1 Inhibitor RN1 Rescues Congenital Dyserythropoietic Anemia Type II

Sequential Infusion of Anti-CD19 and Anti-BCMA Chimeric Antigen Receptor T-Cells: A Promising Treatment Strategy for Refractory Immune-Mediated Platelet Transfusion Refractoriness

SF3B1 Mutation Drives Loss of Y Chromosome in Chronic Lymphocytic Leukemia

Long-Term Remission and Survival in Patients with Rituximab-Refractory/Relapsed B-Cell Non-Hodgkin Lymphoma after Treatment with U16 (CD20 CAR-T cells)

Target Antigen-Expressing T Cells Facilitate CAR-T Cell Eradication of Residual CD19+ B Malignant Cells

Chemotherapy-Free Induction with Venetoclax and Azacitidine, Followed By Tandem CD19/CD22 CAR-T Cell Therapy As First-Line Treatment in Newly Diagnosed High-Risk Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia: A Prospective, Single-Center, Single-Arm, Phase 2 Trial

Safety and Efficacy of CD22/ CD19 CAR-T and Auto-HSCT “Sandwich”Strategy As Consolidation Therapy for Ph Negative B Cell Acute Lymphoblastic Leukemia

Unleashing the Power of CD19 CAR-T in Relapsed AML: Findings from a Prospective Single-Center Clinical Trial

Bird Regimen Followed By Anti-BCMA CAR T-Cell Immunotherapy As First-Line Therapy for Newly Diagnosed Multiple Myeloma: A Prospective, Single-Arm, Phase 3 Trial

5-Year Follow-up of Combined Infusion of Anti-CD19 and Anti-BCMA CAR-T after ASCT for High-Risk Newly Diagnosed Multiple Myeloma

TR4 and BCL11A Repress γ-globin Transcription via Independent Mechanisms

Direct and Indirect Functions of TR4 in the Control of Fetal Hemoglobin Silencing

Whole-Genome CRISPR-Cas9 Screening Identifies Genes Required for Human and Mouse Erythroid Development

The Clinical Outcome of Patients with Refractory/Relapsed Lymphoid Blastic Phase of Chronic Myeloid Leukemia Treated with CAR T-Cells Therapy

Rituximab Improves Clinical Outcomes of CAR-T Therapy for r/r B-ALL Via Sensitizing Leukemia Cells to CAR-T-Mediated Cytotoxicity and Reducing CAR-T Exhaustion

Identifying Novel Regulators of γ-Globin Expression Using a Genome-Scale CRISPR Activation Screen

Safety and Efficacy of CD22/ CD19 CAR-T and Auto-HSCT “Sandwich” Strategy As Consolidation Therapy for Ph Negative B Cell Acute Lymphoblastic Leukemia

Proteogenomic Features Define Novel Subtypes of Mantle Cell Lymphoma

Whole-Genome CRISPR-Cas9 Screen Identifies ZBTB7A As a Potential Therapeutic Target for Cda-II

Phase I Open-Label Single-Arm Study of Sscart-19 in Adult Patients with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia in China

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American Society of Hematology

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American Society of Hematology

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