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Kevyn Hart
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Journal Articles

SF3B1 Mutation Drives Loss of Y Chromosome in Chronic Lymphocytic Leukemia

Mike Fernandez, Lei Yu, Qiong Jia, Xuesong Wang, Kevyn Hart, Zhenyu Jia, Ren-Jang Lin, Lili Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 46.
https://doi.org/10.1182/blood-2024-208209
Published: 2024
Journal Articles

RNA Splicing Factor Mutations Drive Aberrant Canonical and Cryptic Circular RNA Biogenesis in Leukemia

Mike Fernandez, Meiling Jin, Qiong Jia, Yiming Wu, Kevyn Hart, Emilee Bargoma, Joseph Pangallo, Robert K. Bradley, Omar Abdel-Wahab, Zhenyu Jia, Ren-Jang Lin, Lili Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1395.
https://doi.org/10.1182/blood-2023-174135
Published: 2023
Journal Articles

Disrupting MGA-MYC Driven Metabolic Reprogramming in Richter's Syndrome Pre-Clinical Models Via Novel Therapeutic Approaches

Prajish Iyer, Bo Zhang, Tingting Liu, Meiling Jin, Kevyn Hart, Joo Y. Song, Wing C Chan, Tanya Siddiqi, Alexey V Danilov, Steve T Rosen, Lili Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 9842–9843.
https://doi.org/10.1182/blood-2022-162664
Published: 2022
Journal Articles

Combining the Anti-Sickling βAS3-Globin Gene with BCL11A and ZNF410 Double Shmirs for the Treatment of Sickle Cell Disease

Boya Liu, Kevyn Hart, Christian Brendel, Donald B. Kohn, David A. Williams
Journal: Blood
Blood (2022) 140 (Supplement 1): 7786–7787.
https://doi.org/10.1182/blood-2022-163469
Published: 2022
Journal Articles

METTL3 Dysregulates RNA Splicing by Translational Control of Splicing Factors via m 6 A Modification in CLL

Yiming Wu, Meiling Jin, Mike Fernandez, Kevyn Hart, Aijun Liao, Stacey M. Fernandes, Tinisha McDonald, Lucy Ghoda, Daniel Roeth, Markus Kalkum, Raju Pillai, Jianjun Chen, Jennifer R Brown, Alexey V. Danilov, Steven T. Rosen, Tanya Siddiqi, Lili Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 499.
https://doi.org/10.1182/blood-2021-149691
Published: 2021
Journal Articles

R-Loop Associated Mitotic Stress Confers Vulnerabilities in Splicing Factor Mutant Leukemia

Martina Cusan, Meiling Jin, Bo Zhang, Mike Fernandez, Aijun Liao, Lu Yang, Yiming Wu, Prajish Iyer, Kevyn Hart, Catherine Gutierrez, Jeremy Stark, Teresa V. Bowman, Catherine J. Wu, Ren-Jang Lin, Lili Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 3713.
https://doi.org/10.1182/blood-2021-151298
Published: 2021
Journal Articles

MGA deletion Leads to Richter's Transformation Via NME1

Prajish Iyer, Bo Zhang, Tingting Liu, Meiling Jin, Kevyn Hart, Joo Y. Song, John Chan, Raju Pillai, Tanya Siddiqi, Alexey V. Danilov, Steven T. Rosen, Lili Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 252.
https://doi.org/10.1182/blood-2021-148953
Published: 2021
Journal Articles

Integrative Transcriptome and Quantitative Proteome Analyses Identify METTL3 As a Key Regulator for Aberrant RNA Processing in Chronic Lymphocytic Leukemia

Yiming Wu, PhD, Meiling Jin, PhD, Kevyn Hart, BS, Aijun Liao, MD PhD, Stacey M. Fernandes, BS, Tinisha McDonald, BS, Lucy Brown, PhD, Daniel Roeth, PhD, Markus Kalkum, PhD, Raju Pillai, MD, Jianjun Chen, PhD, Jennifer R Brown, MD PhD, Steven T. Rosen, MD, Tanya Siddiqi, MD, Lili Wang, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12.
https://doi.org/10.1182/blood-2020-139841
Published: 2020
Journal Articles

Expression of Sf3b1-K700E accelerates the Development of Chronic Lymphocytic Leukemia in a Del (13q) Murine Model

Bo Zhang, MDPhD, Prajish Iyer, PhD, Meiling Jin, PhD, Elisa Ten Hacken, PhD, Zachary Cartun, BS, Kevyn Hart, BS, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD PhD, Donna S. Neuberg, ScD, Ruben D. Carrasco, MD PhD, Catherine J. Wu, MD, Lili Wang, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4–5.
https://doi.org/10.1182/blood-2020-139096
Published: 2020