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Journal Articles

Molecular determinants of outcome in CLL patients treated on zanubrutinib registration trials

Free
Inhye Ahn, Zunqiu Wang, Svitlana Tyekucheva, Kiyomi Mashima, Stacey Fernandes, Vanitha Ramakrishnan, Jessica Li, Linlin Xu, Rameen Beroukhim, Ignaty Leshchiner, Jennifer Brown
Journal: Blood
Blood (2025) 146 (Supplement 1): 2113.
https://doi.org/10.1182/blood-2025-2113
Published: 2025
Journal Articles

Integrated single-cell RNA sequencing and TCR profiling identifies immune drivers of severe early toxicity in CLL patients treated with idelalisib

Free
Saurabh Yadav, Lu Yang, Zunqiu Wang, Binu Kandathilparambil Sasi, Stacey Fernandes, John-Hanson Machado, Samantha Shupe, Ignaty Leshchiner, Lili Wang, Jennifer Brown
Journal: Blood
Blood (2025) 146 (Supplement 1): 2103.
https://doi.org/10.1182/blood-2025-2103
Published: 2025
Journal Articles

Multi-proteomic analyses provide evidence for origin of a co-existing serum monoclonal gammopathy in CLL/MBL

Free
Uday Aditya Sarkar, Dylan Tabang, Colin McNulty, Sabine Allam, Ayazhan Umutbayeva, Stacey Fernandes, Mariia Mikhaleva, Roberta Santos Azevedo, Zainab Wurie, Ava Bidgoli, Natalie Onofri, Joseph Flinn, Kiyomi Mashima, Ingrid Lourme, Elisavet Vlachonikola, Binu Kandathilparambil Sasi, Paulina Predko, Andreas Agathangelidis, Kenneth Parker, Kostas Stamatopoulos, Irene Ghobrial, Jennifer Brown, Hanno Steen, Paolo Ghia
Journal: Blood
Blood (2025) 146 (Supplement 1): 7408.
https://doi.org/10.1182/blood-2025-7408
Published: 2025
Journal Articles

Acquisition of CLL-like epigenetic and transcriptomic states in low-count MBL

Free
Anja Rathgeber, Stacey Fernandes, Adi Nagler, Shuqiang Li, David Dorfman, Lars Bullinger, Matthew S Davids, Jennifer Brown, Kenneth Livak, Leif Ludwig, Catherine Wu, Livius Penter
Journal: Blood
Blood (2025) 146 (Supplement 1): 3876.
https://doi.org/10.1182/blood-2025-3876
Published: 2025
Journal Articles

SF3B1 mutations are associated with shorter time to first treatment in chronic lymphocytic leukemia

Free
Fernanda Santos Azevedo, Kiyomi Mashima, Ava Bidgoli, Paulina Predko, Mariia Mikhaleva, Stephen Martindale, Stacey Fernandes, Svitlana Tyekucheva, Inhye Ahn, Matthew S Davids, Jennifer Brown
Journal: Blood
Blood (2025) 146 (Supplement 1): 3906.
https://doi.org/10.1182/blood-2025-3906
Published: 2025
Journal Articles

Characterization of IGHV subgroups and their prognostic relevance in CLL

Free
Daniel Sungchul Choi, Uday Aditya Sarkar, Yue Ren, Yinglu Zhou, Roberta S. Azevedo, James Yoon, Kiyomi Mashima, Fernanda Santos Azevedo, Gordon Saksena, Stacey Fernandes, Paulina Predko, Matthew S Davids, Svitlana Tyekucheva, Jennifer Brown, Inhye Ahn
Journal: Blood
Blood (2025) 146 (Supplement 1): 3899.
https://doi.org/10.1182/blood-2025-3899
Published: 2025
Journal Articles

Nodal progression in CLL: Real-world predictors of richter transformation and identification of a distinct high-risk NP-CLL subgroup

Free
Nathalie Javidi-Sharifi, Sobana Balasubramanian, Hannah Lee, Paulina Predko, Svitlana Tyekucheva, Amber Mitchell, Stacey Fernandes, Roberta Santos Azevedo, Erin Parry, Catherine Wu, Matthew S Davids, Jennifer Brown
Journal: Blood
Blood (2025) 146 (Supplement 1): 5682.
https://doi.org/10.1182/blood-2025-5682
Published: 2025
Journal Articles

A Clinical Trial of the STAT3 Inhibitor Pyrimethamine in Chronic Lymphocytic Leukemia

Free
Jennifer R. Brown, MD PhD, Sarah R. Walker, PhD, Lisa N. Heppler, Svitlana Tyekucheva, Erik Nelson, PhD, Josephine L. Klitgaard, MSc, PhD, Maria Nicolais, MD, Yasmin Kroll, Michael Xiang, MD PhD, Jennifer E. Yeh, MD PhD, Mousumi Chaudhury, Zachary T. Giaccone, Stacey Fernandes, Jeffrey G. Supko, PhD, Catherine J. Wu, MD, David A. Frank, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1855.
https://doi.org/10.1182/blood-2018-99-118921
Published: 2018
Journal Articles

Dissecting the Role of Individual Bcl-2 Members in Response and Resistance to Ibrutinib or Venetoclax in CLL

Free
Fabio Brocco, Hanneke ter Burg, Stacey Fernandes, Constantine S. Tam, MBBS, MD FRACP, FRCPA, Francesco Forconi, MD DM, PhD FRCPath, Rachel M Guerra, Gregory Bird, Loren D Walensky, Jennifer R. Brown, MD PhD, Arnon P Kater, Eric Eldering
Journal: Blood
Blood (2017) 130 (Supplement 1): 262.
https://doi.org/10.1182/blood.V130.Suppl_1.262.262
Published: 2017
Journal Articles

Genetic and Transcriptomic Characterization of Marrow Progenitor Cells in Patients with Chronic Lymphocytic Leukemia

Free
Lili Wang, MD PhD, Jean Fan, BS, Shuqiang Li, PhD, Jing Sun, PhD, Zachary Cartun, BS, Sarah Hegert, Rutendo Gambe, Stacey Fernandes, Rahul Satija, Donna S. Neuberg, ScD, Kenneth Livak, Adrian Wiestner, MD, Jennifer R. Brown, MD PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2987.
https://doi.org/10.1182/blood.V130.Suppl_1.2987.2987
Published: 2017
Journal Articles

Idelalisib given front-line for treatment of chronic lymphocytic leukemia causes frequent immune-mediated hepatotoxicity

Free
Clinical Trials & Observations
Benjamin L. Lampson, Siddha N. Kasar, Tiago R. Matos, Elizabeth A. Morgan, Laura Rassenti, Matthew S. Davids, David C. Fisher, Arnold S. Freedman, Caron A. Jacobson, Philippe Armand, Jeremy S. Abramson, Jon E. Arnason, Thomas J. Kipps, Joshua Fein, Stacey Fernandes, John Hanna, Jerome Ritz, Haesook T. Kim, Jennifer R. Brown
Journal: Blood
Blood (2016) 128 (2): 195–203.
https://doi.org/10.1182/blood-2016-03-707133
Published: 2016
Includes: Supplemental data