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Ute Koch
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Journal Articles

Stroma-Driven Notch2 Signaling Controls Naïve B Cell Fate By Regulating Microenvironmental Positioning within the Spleen

Anneka Allman, Brian Gaudette, Samantha Kelly, Nagham Alouche, Leolene Carrington, Eric Perkey, Riley Outen, Ashley Vanderbeck, Katlyn Lederer, Tanner F. Robertson, Janis K. Burkhardt, Anastasia N. Tikhonova, Iannis Aifantis, Ute Koch, Freddy Radtke, Burkhard Ludewig, Lena Tveriakhina, Achim Gossler, Christian W. Siebel, Daniela Gomez Atria, Sanjiv Luther, David Allman, Ivan Maillard
Journal: Blood
Blood (2023) 142 (Supplement 1): 2549.
https://doi.org/10.1182/blood-2023-186941
Published: 2023
Journal Articles

Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL

Mateusz Antoszewski, Nadine Fournier, Gustavo A. Ruiz Buendía, Joao Lourenco, Yuanlong Liu, Tara Sugrue, Christelle Dubey, Marianne Nkosi, Colin E.J. Pritchard, Ivo J. Huijbers, Gabriela C. Segat, Sandra Alonso-Moreno, Elisabeth Serracanta, Laura Belver, Adolfo A. Ferrando, Giovanni Ciriello, Andrew P. Weng, Ute Koch, Freddy Radtke
Journal: Blood
Blood (2022) 139 (16): 2483–2498.
https://doi.org/10.1182/blood.2021012077
Published: 2022
Includes: Supplemental data
Journal Articles

Notch signaling promotes disease initiation and progression in murine chronic lymphocytic leukemia

Delphine Tardivon, Mateusz Antoszewski, Nadine Zangger, Marianne Nkosi, Jessica Sordet-Dessimoz, Rudi Hendriks, Ute Koch, Freddy Radtke
Journal: Blood
Blood (2021) 137 (22): 3079–3092.
https://doi.org/10.1182/blood.2020006701
Published: 2021
Includes: Supplemental data
Journal Articles

Donor T Cells Require Notch Signals but Not Alloantigen Presentation from Specialized Secondary Lymphoid Organ Fibroblasts to Drive Graft-Versus-Host Disease

Eric Perkey, BS, Léolène Carrington, PhD, Jooho Chung, MDPhD, David Granadier, BS, Alexander Dils, Ann Friedman, BS, Anastasia Tikhonova, PhD, Bruce R. Blazar, MD, Ute Koch, PhD, Nathalie Labrecque, PhD, Freddy Radtke, PhD, Chris Siebel, PhD BA, Iannis Aifantis, PhD, Ivan Maillard, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 810.
https://doi.org/10.1182/blood-2018-99-110258
Published: 2018
Journal Articles

Dicer1 imparts essential survival cues in Notch-driven T-ALL via miR-21–mediated tumor suppressor Pdcd4 repression

Fabian Junker, Antoine Chabloz, Ute Koch, Freddy Radtke
Journal: Blood
Blood (2015) 126 (8): 993–1004.
https://doi.org/10.1182/blood-2014-12-618892
Published: 2015
Includes: Supplemental data
Journal Articles

Delta-like Ligands Expressed By Stromal Cells in Secondary Lymphoid Organs Deliver an Early Pulse of Notch Signaling and Drive T Cell Pathogenicity in Acute Graft-Versus-Host Disease

Jooho Chung, BS, Christen L. Ebens, MDMPH, Vedran Radojcic, MD, Ute Koch, PhD, Ann Friedman, BS, Ivy T. Tran, BS, Qian Chai, PhD, Lucas Onder, PhD, Minhong Yan, PhD, Pavan Reddy, MD, Bruce R. Blazar, MD, Burkhard Ludewig, PhD, Christian W. Siebel, PhD, Freddy Radtke, PhD, Ivan Maillard, MD PhD
Journal: Blood
Blood (2014) 124 (21): 841.
https://doi.org/10.1182/blood.V124.21.841.841
Published: 2014
Journal Articles

Delta-Like Notch Ligands Expressed By Host Non-Hematopoietic Radioresistant Cells Regulate Graft-Versus-Host Disease and Extrathymic T Cell Development After Bone Marrow Transplantation

Christen L Ebens, MD, MPH, Jooho Chung, BS, Ute Koch, PhD, Ivy T Tran, BS, Ashley R Sandy-Sloat, PhD, Ann Friedman, BS, Bruce R Blazar, MD, Pavan Reddy, MD, Minhong Yan, PhD, Christian W Siebel, PhD, Freddy Radtke, PhD, Ivan Maillard, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2003.
https://doi.org/10.1182/blood.V122.21.2003.2003
Published: 2013
Journal Articles

Simultaneous loss of β- and γ-catenin does not perturb hematopoiesis or lymphopoiesis

Brief Report
Ute Koch, Anne Wilson, Monica Cobas, Rolf Kemler, H. Robson MacDonald, Freddy Radtke
Journal: Blood
Blood (2008) 111 (1): 160–164.
https://doi.org/10.1182/blood-2007-07-099754
Published: 2008
Includes: Supplemental data
Journal Articles

A Synthetic CD4-CDR3 Peptide Analog Enhances Bone Marrow Engraftment Across Major Histocompatibility Barriers

Ute Koch, Robert Korngold
Journal: Blood
Blood (1997) 89 (8): 2880–2890.
https://doi.org/10.1182/blood.V89.8.2880
Published: 1997