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Journal Articles

Stroma-Driven Notch2 Signaling Controls Naïve B Cell Fate By Regulating Microenvironmental Positioning within the Spleen

Anneka Allman, Brian Gaudette, Samantha Kelly, Nagham Alouche, Leolene Carrington, Eric Perkey, Riley Outen, Ashley Vanderbeck, Katlyn Lederer, Tanner F. Robertson, Janis K. Burkhardt, Anastasia N. Tikhonova, Iannis Aifantis, Ute Koch, Freddy Radtke, Burkhard Ludewig, Lena Tveriakhina, Achim Gossler, Christian W. Siebel, Daniela Gomez Atria, Sanjiv Luther, David Allman, Ivan Maillard
Journal: Blood
Blood (2023) 142 (Supplement 1): 2549.
https://doi.org/10.1182/blood-2023-186941
Published: 2023
Journal Articles

DLBCL-associated NOTCH2 mutations escape ubiquitin-dependent degradation and promote chemoresistance

Nan Zhou, Jaewoo Choi, Grant Grothusen, Bang-Jin Kim, Diqiu Ren, Zhendong Cao, Yiman Liu, Qinglan Li, Arati Inamdar, Thomas Beer, Hsin-Yao Tang, Eric Perkey, Ivan Maillard, Roberto Bonasio, Junwei Shi, Marco Ruella, Liling Wan, Luca Busino
Journal: Blood
Blood (2023) 142 (11): 973–988.
https://doi.org/10.1182/blood.2022018752
Published: 2023
Includes: Supplemental data
Journal Articles

Fibroblastic Stromal Cells Expressing Delta-like Notch Ligands Control Extrathymic T Cell Development in Mesenteric Lymph Nodes

Ashley Vanderbeck, Samantha Kelly, Leolene Carrington, Eric Perkey, Anneka Allman, Frederick Allen, Joshua D Brandstadter, Burkhard Ludewig, Chris Siebel
Journal: Blood
Blood (2022) 140 (Supplement 1): 7363.
https://doi.org/10.1182/blood-2022-169178
Published: 2022
Journal Articles

Graft-Versus-Host Disease Induces Immune Dysregulation through Irreversible Damage to Specialized Immune-Interacting Fibroblastic Stromal Cells in Secondary Lymphoid Organs

Leolene Carrington, Shovik Bandyopadhyay, Katlyn Lederer, Samantha Kelly, Ashley Vanderbeck, Gloria Jih, Frederick Allen, Daniela Gómez Atria, Anneka Allman, Eric Perkey, Kai Tan, Norbert Pardi, Burkhard Ludewig, Ronjon Chakraverty, Ivan Maillard
Journal: Blood
Blood (2022) 140 (Supplement 1): 7334–7335.
https://doi.org/10.1182/blood-2022-167650
Published: 2022
Journal Articles

Zinc: a damage signal promoting thymic repair

Eric Perkey, Ivan Maillard
Journal: Blood
Blood (2022) 139 (25): 3569–3570.
https://doi.org/10.1182/blood.2022016333
Published: 2022
Journal Articles

Stromal Notch Ligands Drive Notch2-Dependent Transdifferentiation of Follicular B Cells into Marginal Zone-like B Cells in Lymphopenic Environments

Daniela Gómez Atria, PhD, Brian T. Gaudette, PhD, Eric Perkey, BS, Jennifer Londregan, BS, Samantha Kelly, BS, Burkhard Ludewig, PhD, Chris Siebel, PhD BA, Russell J. H. Ryan, MD, Warren S. Pear, MDPhD, David Allman, PhD, Ivan Maillard, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–39.
https://doi.org/10.1182/blood-2020-142474
Published: 2020
Journal Articles

Dll1 and Dll4 Notch Ligands Prime T Cell Alloimmunity and Are Expressed in Non-Overlapping Populations of Fibroblastic Stromal Cells in Spleen and Lymph Nodes at the Onset of Gvhd

Joshua D Brandstadter, MD PhD, Eric Perkey, Brian T. Gaudette, PhD, Léolène Carrington, PhD, Daniela Gomez-Atria, PhD, Bruce R. Blazar, MD, Burkhard Ludewig, PhD, Anastasia Tikhonova, PhD, Iannis Aifantis, PhD, David Allman, PhD, Ivan Maillard, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 588.
https://doi.org/10.1182/blood-2019-123533
Published: 2019
Journal Articles

Donor T Cells Require Notch Signals but Not Alloantigen Presentation from Specialized Secondary Lymphoid Organ Fibroblasts to Drive Graft-Versus-Host Disease

Eric Perkey, BS, Léolène Carrington, PhD, Jooho Chung, MDPhD, David Granadier, BS, Alexander Dils, Ann Friedman, BS, Anastasia Tikhonova, PhD, Bruce R. Blazar, MD, Ute Koch, PhD, Nathalie Labrecque, PhD, Freddy Radtke, PhD, Chris Siebel, PhD BA, Iannis Aifantis, PhD, Ivan Maillard, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 810.
https://doi.org/10.1182/blood-2018-99-110258
Published: 2018
Journal Articles

Notch Signaling Mediated By Dll1/4 Notch Ligands Controls the Pathogenesis of Both Multi-Organ System Non-Sclerodermatous and Sclerodermatous Chronic Graft-Versus-Host Disease

Vedran Radojcic, MD, Ryan P Flynn, PhD, Jooho Chung, BS, Jing Du, Eric Perkey, BS, Katelyn Paz, Michael Zaiken, Ann Friedman, Minhong Yan, PhD, Christian W. Siebel, PhD, Bruce R. Blazar, MD, Ivan Maillard, MD PhD
Journal: Blood
Blood (2016) 128 (22): 805.
https://doi.org/10.1182/blood.V128.22.805.805
Published: 2016