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Journal Articles

Identification of a Novel FAM135B Cancer Susceptibility Mutation in a Family with Multiple Cases of MLL -Rearranged AML

Li-li PAN, Yanling Sun, Xiaolin Lai, Luya Ye, Xue-chun Wang, Zhi-xiang Chen, Yuanhua Cai, Yi Zheng, Yang Li, Ya-ping Wang, Xin Liu, Shao-yuan Wang, Qian-fei Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 9107.
https://doi.org/10.1182/blood-2022-165170
Published: 2022
Journal Articles

Identifying and Targeting Cytotoxic Tumor-Associated Macrophages in Epstein-Barr Virus-Driven Lymphoproliferative Disease

John T. Patton, PhD, Monica L Mitchell, Li Pan, PhD, A. Douglas Kinghorn, PhD, D.Sc, Michael R. Grever, MD, David M. Lucas, PhD, Robert A. Baiocchi, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4489.
https://doi.org/10.1182/blood.V124.21.4489.4489
Published: 2014
Journal Articles

Silvestrol Modulates Indirect Anti-Tumor Activity and Potentiates Immune Response To Epstein-Barr Virus-Driven Lymphoproliferative Disease

John T. Patton, Alex S. Hartlage, Li Pan, PhD, Mark E Lustberg, MD, PhD, Callie M. Drohan, Marisa F. Martin, A. Douglas Kinghorn, Ph.D., D.Sc, Michael A. Caligiuri, MD, Michael R. Grever, MD, David M. Lucas, PhD, Robert A. Baiocchi, M.D., Ph.D.
Journal: Blood
Blood (2013) 122 (21): 4422.
https://doi.org/10.1182/blood.V122.21.4422.4422
Published: 2013
Journal Articles

Phenothiazines Induce Apoptosis in T-Cell Acute Lymphoblastic Leukemia by Activating the Phosphatase Activity of the PP2A Tumor Suppressor

Alejandro Gutierrez, MD, Alex Kentsis, MD, PhD, Li Pan, PhD, Frederic Baleydier, M.D Ph.D, Jason Marineau, PhD, Ruta Grebliunaite, Elena Kozakewich, Casie Reed, BS, Francoise Pflumio, Sandrine Poglio, Benjamin Uzan, Paul A. Clemons, Lynn VerPlank, W. Frank An, Jason Burbank, Stephanie Norton, Nicola J Tolliday, PhD, Hanno Steen, PhD, James E Bradner, MD, A. Thomas Look, M.D., Jon C Aster, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3558.
https://doi.org/10.1182/blood.V120.21.3558.3558
Published: 2012
Journal Articles

Translational Research From the Tropical Forest: Silvestrol, a Natural Product From the Plant Aglaia Foveolata inhibits the Expression of Tyrosine Kinases and Shows a Significant In Vivo Activity in Acute Myeloid Leukemia (AML)

Houda Alachkar, PharmD, M.S, Ramasamy Santhanam, PhD, David M. Lucas, PhD, Sebastian Schwind, MD, Christopher Hickey, M.S, Jiuxia Pang, Danilo Perrotti, MD, PhD, Li Pan, PhD, A Douglas Kinghorn, Ph.D., D.Sc, Guido Marcucci, MD, Michael R Grever, MD
Journal: Blood
Blood (2011) 118 (21): 2616.
https://doi.org/10.1182/blood.V118.21.2616.2616
Published: 2011
Journal Articles

Targeting the Cyclin D - CDK4/6 - Rb Axis in Mantle Cell Lymphoma with the Novel Translation Inhibitor Silvestrol,

Lapo Alinari, MD., Ph.D., Ryan B. Edwards, Courtney J. Prince, William H. Towns, Rajeswaran Mani, DVM, Amy Lehman, Xiaoli Zhang, PhD, MS, David Jarjoura, PhD, Li Pan, PhD, A. Douglas Kinghorn, PhD, DSc, Michael R. Grever, M.D., Robert A. Baiocchi, M.D., Ph.D., David M. Lucas, PhD
Journal: Blood
Blood (2011) 118 (21): 3498.
https://doi.org/10.1182/blood.V118.21.3498.3498
Published: 2011
Journal Articles

Silvestrol Modulates Direct Anti-Tumor Activity Against Epstein-Barr Virus (EBV)-Associated Lymphomas While Sparing Innate and Antigen Specific Adaptive Immunity

John T. Patton, Mark E Lustberg, MD, PhD, Sabrina L Garman, A Douglas Kinghorn, Ph.D., D.Sc, Li Pan, PhD, David M. Lucas, PhD, Michael R. Grever, M.D., Robert A. Baiocchi, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 104.
https://doi.org/10.1182/blood.V118.21.104.104
Published: 2011
Journal Articles

Resistance to the Novel Translation Inhibitor Silvestrol Is Mediated by Elevated Mcl-1 Expression.

David M. Lucas, Ellen J. Sass, Ryan B. Edwards, Li Pan, Gerard Lozanski, Nyla A. Heerema, John C. Byrd, A. Douglas Kinghorn, Michael R. Grever
Journal: Blood
Blood (2009) 114 (22): 1737.
https://doi.org/10.1182/blood.V114.22.1737.1737
Published: 2009