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Christopher Famulare
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Journal Articles

Barriers to Immune Effector Cell Therapy: Rapid Disease Progression, Concern for Toxicity, and Lack of Appropriate Trials Drive Non-Receipt after Referral at a Large Academic Center

Yannis K. Valtis, Kuo-Kai Chin, Meira Yisraeli Salman, Leora Boussi, Briana Cadzin, Carina Mcloughlin, Elizabeth Cathcart, Paul Davis, Chelsea Brooklyn, Todd Goldstein, Christopher Famulare, Gunjan L. Shah, Moneeza Walji, Alexander P. Boardman, Roni Shouval, Eytan M. Stein, Sham Mailankody, Maria Lia Palomba, Gilles Salles, Sergio Giralt, Miguel Angel Perales, Jae H. Park
Journal: Blood
Blood (2024) 144 (Supplement 1): 781.
https://doi.org/10.1182/blood-2024-200915
Published: 2024
Journal Articles

HMA/Ven Treatment Modifications and Associated Outcomes in IDH -Mutant AML

Kuo-Kai Chin, Andriy Derkach, Christopher Famulare, Gaurav Gupta, Prabhakar Borge, Mark Blaine Geyer, Aaron D. Goldberg, Tamanna Haque, Jae H. Park, Lindsey Roeker, Martin S. Tallman, Maximilian Stahl, Eytan M. Stein
Journal: Blood
Blood (2024) 144 (Supplement 1): 5962.
https://doi.org/10.1182/blood-2024-211733
Published: 2024
Journal Articles

Patients with AML and an IDH2-R172 Mutation Exhibit a Unique Response to Intensive Induction Chemotherapy, Suggesting Futility of Mid-Cycle Bone Marrow Biopsy and Caution When Considering Re-Induction

Meira Yisraeli Salman, Alexander R. Terry, Andriy Derkach, David Nemirovsky, Kuo-Kai Chin, Yannis K. Valtis, Leora Boussi, Theresa Spivey, Wenbin Xiao, Christopher Famulare, Jenna Ciervo, Jacob M. Rowe, Martin S. Tallman, Eytan M. Stein
Journal: Blood
Blood (2024) 144 (Supplement 1): 2847.
https://doi.org/10.1182/blood-2024-193242
Published: 2024
Journal Articles

Deconvoluting Clonal and Cellular Architecture in IDH -Mutant Acute Myeloid Leukemia

Maria Sirenko, Soobeom Lee, Zhengxi Sun, Ronan Chaligne, Georgios Asimomitis, Charlotte K Brierley, Elsa Bernard, Sheng F. Cai, Robert M Myers, Bettina Nadorp, Max F Levine, Dylan Domenico, Juan E Arango Ossa, Juan Santiago Medina Martinez, Kamal Menghrajani, Audrey Lasry, Alice Mims, Helee Desai, Andrea Laganson, Christopher Famulare, Minal Patel, Gerard Lozanski, Sanam Loghavi, Kelly L. Bolton, Aaron D. Viny, Mikhail Roshal, Ross L Levine, Eytan M. Stein, Dan A. Landau, Ann-Kathrin Eisfeld, Iannis Aifantis, Elli Papaemmanuil
Journal: Blood
Blood (2023) 142 (Supplement 1): 1591.
https://doi.org/10.1182/blood-2023-186322
Published: 2023
Journal Articles

Clinical Factors but Not Somatic Mutations Predict for Survival in Patients with Myelofibrosis Undergoing Allogeneic Hematopoietic Cell Transplant: Analysis of the North American Myelofibrosis Transplant Outcome (NAMTO) Study

Helen Ajufo, Andriy Derkach, Raajit K. Rampal, Christopher Famulare, David Nemirovsky, Jordan Chervin, Vincent Ho, Vikas Gupta, Auro Viswabandya, H. Joachim Deeg, Tim Monahan, Tania Jain, Richard J. Jones, Jeanne Palmer, Aaron T. Gerds, Alla Keyzner, Jonathan Lagdameo, Alexandra Gomez-Arteaga, Koen Van Besien, Nikolai A. Podoltsev, Christian Puzo, Satyajit Kosuri, Idoroenyi Amanam, Roni Tamari
Journal: Blood
Blood (2023) 142 (Supplement 1): 3181.
https://doi.org/10.1182/blood-2023-173441
Published: 2023
Journal Articles

Despite High Rates of Remission, Treatment of IDH-Mutant AML with Hypomethylating Agents and Venetoclax Is Associated with Frequent Treatment Delays, Modifications, and Transfusions

Kuo-Kai Chin, Andriy Derkach, Christopher Famulare, Gaurav Gupta, Prabhakar Borge, Ellin Berman, Mark Blaine Geyer, Aaron D. Goldberg, Tamanna Haque, Raajit K. Rampal, Jae H. Park, Lindsey E. Roeker, Martin S. Tallman, Eytan M. Stein
Journal: Blood
Blood (2023) 142 (Supplement 1): 1519.
https://doi.org/10.1182/blood-2023-182012
Published: 2023
Journal Articles

MPN Transformation Is Characterized By Heterogeneous Shifts in Lineage Character

Deepika Dilip, Kamal Menghrajani, Jacob Glass, Raajit K. Rampal, Christopher Famulare, Maria Sirenko, Ross L Levine, Richard Koche
Journal: Blood
Blood (2023) 142 (Supplement 1): 749.
https://doi.org/10.1182/blood-2023-189767
Published: 2023
Journal Articles

TP53 Y220C Mutations in Patients with Myeloid Malignancies

Georgina Gener-Ricos, Jan Philipp Bewersdorf, Sanam Loghavi, Aaron D. Goldberg, Christopher Famulare, Ghayas C. Issa, Gautam Borthakur, Tapan M. Kadia, Bing Z. Carter, Keyur P. Patel, Michael Andreeff, Eytan M. Stein, Courtney D. DiNardo
Journal: Blood
Blood (2023) 142 (Supplement 1): 1477.
https://doi.org/10.1182/blood-2023-189343
Published: 2023
Journal Articles

Safety and efficacy of CPX-351 in younger patients (<60 years old) with secondary acute myeloid leukemia

Clinical Trials & Observations
Amanda Przespolewski, Aaron D. Goldberg, Chetasi Talati, Salman Fazal, Pankit Vachhani, Srinivasa R. Sanikommu, Swapna Thota, Julian Waksal, Brian Ball, Christopher Famulare, Maximilian Stahl, Jeffrey Baron, Elizabeth A. Griffiths, James E. Thompson, Kendra Sweet, Eunice S. Wang
Journal: Blood
Blood (2023) 141 (12): 1489–1493.
https://doi.org/10.1182/blood.2022016678
Published: 2023
Includes: Supplemental data
Journal Articles

Single Cell Genotypic and Phenotypic Analysis of Measurable Residual Disease in Acute Myeloid Leukemia

Troy Robinson, Robert L. Bowman, Sonali Persaud, Ying Liu, Qi Gao, Jing-Ping Zhang, Xiaotian Sun, Adam Sciambi, Aaron Llanso, Christopher Famulare, Aaron D Goldberg, Ahmet Dogan, Mikhail Roshal, Ross L. Levine, Wenbin Xiao
Journal: Blood
Blood (2022) 140 (Supplement 1): 2275–2277.
https://doi.org/10.1182/blood-2022-166501
Published: 2022
Journal Articles

Whole Genome Sequencing Comparison of Acute Myeloid Leukemia at Presentation and Remission Predicts Patient Outcome

Andrea B Moffitt, Joan Alexander, Asya Stepansky, Christopher Famulare, Carlos A Lopez, Nausheen Hakim, Vernon Wu, Zihua Wang, Jonathan E. Kolitz, Nicholas Chiorazzi, Steven L Allen, Ross L. Levine, Dan Levy, Michael Wigler
Journal: Blood
Blood (2022) 140 (Supplement 1): 9167–9169.
https://doi.org/10.1182/blood-2022-163607
Published: 2022
Journal Articles

Erythroid and Megakaryocytic Differentiation Program in JAK2 -Mutated Acute Myeloid Leukemia with or without Antecedent Myeloproliferative Neoplasm

Ying Liu, Shenon Sethi, Richard Koche, Qi Gao, Deepika Dilip, Jacob L Glass, Pallavi K Galera, Sonali Persaud, Tanmay Mishra, Xiaotian Sun, Dory Londono, Robert Cimera, Menglei Zhu, Christopher Famulare, Jeeyeon Baik, Himanshu Bhurtel, Maria E. Arcila, Ahmet Dogan, Ross L. Levine, Yanming Zhang, Mikhail Roshal, Raajit K Rampal, Wenbin Xiao
Journal: Blood
Blood (2022) 140 (Supplement 1): 9160–9162.
https://doi.org/10.1182/blood-2022-169215
Published: 2022
Journal Articles

Comparing Outcomes between Liposomal Daunorubicin/Cytarabine (CPX-351) and HMA+Venetoclax As Frontline Therapy in Acute Myeloid Leukemia

Justin Grenet, Akriti G Jain, Madelyn Burkart, Julian Waksal, Christopher Famulare, Yazan Numan, Maximilian Stahl, Zoe Mckinnell, Brian Ball, Xiaoyue Ma, Paul J Christos, Ellen Ritchie, Michael B. Samuel, Justin D. Kaner, Sangmin Lee, Aaron D Goldberg, Shira Dinner, Kendra Sweet, Gail J. Roboz, Pinkal Desai
Journal: Blood
Blood (2021) 138 (Supplement 1): 32.
https://doi.org/10.1182/blood-2021-145947
Published: 2021
Journal Articles

Clinical and Genomic Characterization of Secondary Acute Myeloid Leukemia with Mixed Phenotype

Pallavi Galera, Alexander Chan, Andriy Derkach, Ying Liu, Jeeyeon Baik, Christopher Famulare, Allison Sigler, Maria E. Arcila, Douglas A Mata, Ahmet Dogan, Martin S. Tallman, Ross L. Levine, Yanming Zhang, Mikhail Roshal, Jacob L Glass, Wenbin Xiao
Journal: Blood
Blood (2021) 138 (Supplement 1): 687.
https://doi.org/10.1182/blood-2021-151263
Published: 2021
Journal Articles

The Genomic Landscape of Waldenström Macroglobulinemia Reveals Sustained Germinal Center Activity and Late-Developing Copy Number Aberrations

Kylee H Maclachlan, Tina Bagratuni, Efstathios Kastritis, Bachisio Ziccheddu, Sydney X. Lu, Venkata D Yellapantula, Christopher Famulare, Benjamin Diamond, Monika Chojnacka, Arjun Raj, Emilia Mason, David G. Coffey, James E. Hoffman, Dickran Kazandjian, Andriy Derkach, Elli Papaemmanuil, Ahmet Dogan, Alexander Lesokhin, Ola Landgren, M. Lia Palomba, Francesco Maura, Meletios-Athanasios Dimopoulos
Journal: Blood
Blood (2021) 138 (Supplement 1): 2394.
https://doi.org/10.1182/blood-2021-148095
Published: 2021
Journal Articles

Safety and Efficacy of CPX-351 in Younger Patients < 60 Years Old with Secondary Acute Myeloid Leukemia: An Updated Analysis

Amanda Przespolewski, Aaron D Goldberg, Chetasi Talati, Salman Fazal, Pankit Vachhani, Srinivasa Reddy R. Sanikommu, Swapna Thota, Julian Waksal, Brian Ball, Christopher Famulare, Maximilian Stahl, Zoe Mckinnell, Jeffrey Baron, Elizabeth A. Griffiths, James E. Thompson, Kendra Sweet, Eunice S. Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1264.
https://doi.org/10.1182/blood-2021-153791
Published: 2021
Journal Articles

Chemotherapy-Related Mutational Signatures Reveal the Origins of Therapy-Related Myeloid Neoplasms

Benjamin Diamond, Bachisio Ziccheddu, Eileen M Boyle, Kylee H Maclachlan, Juan Arango Ossa, Justin Taylor, Justin Watts, Sydney X. Lu, Venkata D Yellapantula, Christopher Famulare, Monika Chojnacka, Arjun Raj Rajanna, Emilia Mason, David G. Coffey, James E. Hoffman, Dickran Kazandjian, Terrence J Bradley, Menglei Zhu, Niccolo Bolli, Elli Papaemmanuil, Kelly L. Bolton, Michael Scordo, Oscar B Lahoud, Eytan M. Stein, Craig S. Sauter, Hani Hassoun, Sham Mailankody, Neha Korde, Malin Hultcrantz, Urvi A Shah, Gunjan L Shah, Jae H Park, Heather J Landau, Karuna Ganesh, Mikkael A. Sekeres, Stephen Nimer, David J. Chung, Caleb Ho, Mikhail Roshal, Alexander Lesokhin, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2021) 138 (Supplement 1): 3271.
https://doi.org/10.1182/blood-2021-145927
Published: 2021
Journal Articles

Loss of LKB1/ STK11 Facilitates Leukemic Progression of the Myeloproliferative Neoplasms

Christian Marinaccio, MSc, Praveen K Suraneni, PhD, Hamza Celik, PhD, Andrew Volk, PhD, Jeremy Q. Wen, MD PhD, Te Ling, PhD, Terra Lasho, PhD, Richard P. Koche, PhD, Christopher Famulare, MS, Brady L. Stein, MD, Sandeep Gurbuxani, MBBS, PhD, Ronald Hoffman, MD, Naseema Gangat, MBBS, Navdeep Chandel, Ross L. Levine, MD, Raajit K. Rampal, MD PhD, Grant Challen, Ayalew Tefferi, MD, John D. Crispino, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-140557
Published: 2020
Journal Articles

Clinical Outcomes of Acute Myeloid Leukemia Patients Bridged to Allogeneic Stem Cell Transplant By Venetoclax Combination Therapy

Maximilian Stahl, MD, Kamal Menghrajani, MD, Andriy Derkach, PhD, Susan DeWolf, MD, Josel D Ruiz, MPH, Doris M Ponce, MD, Brian C. Shaffer, MD, Roni Tamari, MD, James W. Young, MD, Juliet Barker, MBBS, Ann A. Jakubowski, MDPhD, Boglarka Gyurkocza, MD, Alexander Chan, Wenbin Xiao, MD PhD, Jacob L Glass, MDPhD, Amber C. King, PharmD, BCOP, Sheng F Cai, MDPhD, Anthony Daniyan, MD, Christopher Famulare, MS, Bernadette M. Cuello, BSN, MSN, NP, RN, Troy Z. Horvat, PharmD, BCOP, Eytan M. Stein, MD, Mikhail Roshal, MD PhD, Sergio Giralt, MD, Miguel-Angel Perales, MD, Christina Cho, MD, Martin S. Tallman, MD, Aaron D Goldberg, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-137749
Published: 2020
Journal Articles

Analysis of the Global Methylation Profile of Accelerated and Blast Phase Myeloproliferative Neoplasms and Its Association with Response to Decitabine-Based Therapy

Raajit K. Rampal, MD PhD, Qin Yang, Richard P. Koche, PhD, Erin McGovern, BA, Christopher Famulare, MS, Rona Singer Weinberg, PhD, John Mascarenhas, MD, Ross L. Levine, MD, Ronald Hoffman, MD, Maria E. Figueroa, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–20.
https://doi.org/10.1182/blood-2020-139505
Published: 2020