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Adam Sciambi
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Journal Articles

Single-Cell Multi-Omic Analysis of AML MRD Reveals Differences in Clonal Architecture between Relapse and Non-Relapse Cases

Adam Sciambi, Daniel Mendoza, Kathryn Thompson, Lan W. Beppu, Benjamin Geller, Indira Krishnan, Lubna Nousheen, Shu Wang, Charlie Murphy, Jerald P. Radich, Todd E. Druley
Journal: Blood
Blood (2024) 144 (Supplement 1): 1568.
https://doi.org/10.1182/blood-2024-210840
Published: 2024
Journal Articles

Using Single Cell Multi-Omic Clonal Tracking in SMM to Identify Clones That Progress to MM and Harbor Treatment Resistance Features

Adam Sciambi, Daniel Mendoza, Indira Krishnan, Joanne Nguyen, Lubna Nousheen, Benjamin Geller, Cedric Dos Santos, Vivek S. Chopra, Habib Hamidi, Michael Nixon, Yann Nouet, Todd E. Druley, Herve Avet-Loiseau
Journal: Blood
Blood (2024) 144 (Supplement 1): 4722.
https://doi.org/10.1182/blood-2024-205533
Published: 2024
Journal Articles

Single-Cell Multiomic Profiling of TP53 Mutated Myelodysplastic Neoplasms - All Clones Are Not Equal

Onima Chowdhury, Kristian Gurashi, Amy Wood, Ivan Lukic, Adam Sciambi, Lynn Quek, Daniel H Wiseman, Adam J Mead
Journal: Blood
Blood (2024) 144 (Supplement 1): 3615.
https://doi.org/10.1182/blood-2024-210047
Published: 2024
Journal Articles

A Multiomic, Single-Cell Measurable Residual Disease (scMRD) Assay for Simultaneous Assessment of DNA Mutations and Surface Immunophenotypes in Acute Myeloid Leukemia

Kathryn Thompson, Benjamin Geller, Lubna Nousheen, Indira Krishnan, Shu Wang, Daniel Mendoza, Todd E. Druley, Adam Sciambi
Journal: Blood
Blood (2024) 144 (Supplement 1): 6168.
https://doi.org/10.1182/blood-2024-204025
Published: 2024
Journal Articles

Clonal Dynamics of Leukemic and Clonal Hematopoiesis Mutations Predict Relapse in Single Cell MRD Analysis of AML in First Complete Remission

Enise Ceran, Anne Kathrin Merbach, Christian Rohde, Robert Durruthy-Durruthy, Adam Sciambi, Michelle Lotze, Gema Fuerte, Matteo Cattaneo, Ivan Lukic, Maxi Wass, Judith Schaffrath, Christoph Röllig, Richard F. Schlenk, Marina Scheller, Simone Kowoll, Jörg Steighardt, Bayram Edemir, Beatrice Ludwig-Kraus, Lutz P. Mueller, Sabine Edemir, Abi Vainstein-Haras, Ella Sorani, Irit Gliko Kabir, Shaul Kadosh, Cora Gromann, Andreas Wienke, Claudia Wickenhauser, Claudia D Baldus, Uwe Platzbecker, Hubert Serve, Martin Bornhäuser, Carsten Müller-Tidow
Journal: Blood
Blood (2024) 144 (Supplement 1): 4337.
https://doi.org/10.1182/blood-2024-209953
Published: 2024
Journal Articles

RAS/RAF landscape in monoclonal plasma cell conditions

Brief Report
Anais Schavgoulidze, Jill Corre, Mehmet Kemal Samur, Celine Mazzotti, Luka Pavageau, Aurore Perrot, Titouan Cazaubiel, Xavier Leleu, Margaret Macro, Karim Belhadj, Murielle Roussel, Sabine Brechignac, Lydia Montes, Denis Caillot, Laurent Frenzel, Philippe Rey, Jean-Marc Schiano de Colella, Thomas Chalopin, Caroline Jacquet, Valentine Richez, Frederique Orsini-Piocelle, Jean Fontan, Salomon Manier, Ludovic Martinet, Adam Sciambi, Mohamad Mohty, Herve Avet-Loiseau
Journal: Blood
Blood (2024) 144 (2): 201–205.
https://doi.org/10.1182/blood.2023022295
Published: 2024
Includes: Supplemental data
Journal Articles

Multiomic Single-Cell Sequencing May Distinguish BCR-ABL-Mutated Acute Myeloid Leukemia (AML) from Blast Crisis Chronic Myelogenous Leukemia (BC-CML)

Vanessa E. Kennedy, Cheryl A C Peretz, Andrew Koh, Elaine Tran, Dalia Dhingra, Saurabh Gulati, Adam Sciambi, Olga Sala-Torra, Lan Beppu, Aaron C. Logan, Alexander Perl, Wendy Stock, Geoffrey L Uy, Ann-Kathrin Eisfeld, Jerald P. Radich, Catherine C. Smith
Journal: Blood
Blood (2023) 142 (Supplement 1): 4334.
https://doi.org/10.1182/blood-2023-182454
Published: 2023
Journal Articles

Single Cell Multi-Omic Correlation of Single Nucleotide Variants, Copy Number Variation and Surface Epitopes for Clonal Profiling of Myeloma

Adam Sciambi, Cedric Dos Santos, Yang Li, Joanne Bio Nguyen, Priyam Priyam, Vivek Chopra, Habib Hamidi, Michael Nixon, Yann Nouet, Todd E. Druley, Herve Avet-Loiseau
Journal: Blood
Blood (2023) 142 (Supplement 1): 4714.
https://doi.org/10.1182/blood-2023-189518
Published: 2023
Journal Articles

Illustrating Heterogeneity in AML By Leveraging Multimodal Analysis of DNA, Surface Proteins, and Intracellular Proteins in Single Cells

Prithvi Singh, Dalia Dhingra, Saurabh Parikh, Adam Sciambi, Aik Ooi
Journal: Blood
Blood (2022) 140 (Supplement 1): 11806.
https://doi.org/10.1182/blood-2022-170248
Published: 2022
Journal Articles

Single Cell Genotypic and Phenotypic Analysis of Measurable Residual Disease in Acute Myeloid Leukemia

Troy Robinson, Robert L. Bowman, Sonali Persaud, Ying Liu, Qi Gao, Jing-Ping Zhang, Xiaotian Sun, Adam Sciambi, Aaron Llanso, Christopher Famulare, Aaron D Goldberg, Ahmet Dogan, Mikhail Roshal, Ross L. Levine, Wenbin Xiao
Journal: Blood
Blood (2022) 140 (Supplement 1): 2275–2277.
https://doi.org/10.1182/blood-2022-166501
Published: 2022
Journal Articles

Assessment of Next Generation Sequencing Approaches for the Cytogenetic and Molecular Evaluation of Acute Myeloid Leukemia

Laura W. Dillon, Xijun Zhang, Meghali Goswami, Gauthaman Sukumar, Jack Ghannam, Katherine E. Lindblad, Adam Sciambi, Robert Durruthy-Durruthy, Clifton L. Dalgard, Matthew D. Wilkerson, Christopher S. Hourigan
Journal: Blood
Blood (2021) 138 (Supplement 1): 271.
https://doi.org/10.1182/blood-2021-148128
Published: 2021
Journal Articles

High-Throughput Single-Cell DNA Sequencing of AML Tumors with Droplet Microfluidics

Dennis J. Eastburn, PhD, Maurizio Pellegrino, PhD, Adam Sciambi, PhD, Sebastian Treusch, PhD, Kaustubh Gokhale, PhD, Jose Jacob, MS, Tina Chen, MS, Jairo Matthews, BA, Kiyomi Morita, MD, Keith Jones, PhD, Koichi Takahashi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3965.
https://doi.org/10.1182/blood.V130.Suppl_1.3965.3965
Published: 2017