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Claudia D Baldus
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Journal Articles

Mutational and transcriptional landscape of pediatric B-cell precursor lymphoblastic lymphoma

Emma Kroeze, Ingram Iaccarino, Michelle M. Kleisman, Mayukh Mondal, Thomas Beder, Mouhamad Khouja, Marc P. Höppner, Marijn A. Scheijde-Vermeulen, Lennart A. Kester, Monika Brüggemann, Claudia D. Baldus, Gunnar Cario, Reno S. Bladergroen, Nathalie Garnier, Andishe Attarbaschi, Jaime Verdu-Amorós, Rosemary Sutton, Elizabeth Macintyre, Kenneth Scholten, Laura Arias Padilla, Birgit Burkhardt, Auke Beishuizen, Monique L. den Boer, Roland P. Kuiper, Jan L. C. Loeffen, Judith M. Boer, Wolfram Klapper
Journal: Blood
Blood (2024) 144 (1): 74–83.
https://doi.org/10.1182/blood.2024023938
Published: 2024
Includes: Supplemental data
Journal Articles

Developmental trajectories and cooperating genomic events define molecular subtypes of BCR :: ABL1 -positive ALL

Clinical Trials & Observations Brief Report
Lorenz Bastian, Thomas Beder, Malwine J. Barz, Sonja Bendig, Lorenz Bartsch, Wencke Walter, Nadine Wolgast, Björn Brändl, Christian Rohrandt, Björn-Thore Hansen, Alina M. Hartmann, Katharina Iben, Dennis Das Gupta, Miriam Denker, Johannes Zimmermann, Michael Wittig, Guranda Chitadze, Martin Neumann, Folker Schneller, Walter Fiedler, Björn Steffen, Matthias Stelljes, Christoph Faul, Stefan Schwartz, Franz-Josef Müller, Gunnar Cario, Lana Harder, Claudia Haferlach, Heike Pfeifer, Nicola Gökbuget, Monika Brüggemann, Claudia D. Baldus
Journal: Blood
Blood (2024) 143 (14): 1391–1398.
https://doi.org/10.1182/blood.2023021752
Published: 2024
Includes: Supplemental data
Journal Articles

Impact of KMT2A -PTD Mutational Subgroups on Outcome of AML Patients after Induction Therapy and Allogeneic Hematopoietic Cell Transplantation

Desiree Kunadt, Sven Zukunft, Klaus H Metzeler, Christoph Röllig, Christoph Schliemann, Jan Braess, Carsten Müller-Tidow, Alwin Kraemer, Sebastian Scholl, Inken Hilgendorf, Edgar Jost, Björn Steffen, Gesine Bug, Hermann Einsele, Kerstin Schäfer-Eckart, Stefan W. Krause, Mathias Hänel, Thomas Schroeder, Martin Kaufmann, Jan Moritz Middeke, Katja Sockel, Leo Ruhnke, Uwe Platzbecker, Hubert Serve, Matthias Stelljes, Claudia D Baldus, Andreas Neubauer, Johannes Schetelig, David Poitz, Christian Thiede, Martin Bornhäuser, Friedrich Stölzel
Journal: Blood
Blood (2023) 142 (Supplement 1): 2236.
https://doi.org/10.1182/blood-2023-187273
Published: 2023
Journal Articles

In-Depth Immune Profiling in Children with BCP-ALL within the AIEOP-BFM ALL 2017 Study

Anna Laqua, Hartmann Raifer, Miriam Kelm, Johanna Horns, Arunabh Sharma, Anja Möricke, Michaela Vossen-Gajcy, Julia Alten, Lena Fischer-Riepe, Bianca Altvater, Mahdi Rasa, Britta Kehden, Constantin Proske, Jan Kässens, Thomas Beder, Sonja Bendig, Nadine Wolgast, Lorenz Bastian, Matthias Ritgen, Magdalena Huber, Astrid Dempfle, Claudia D Baldus, Gunnar Cario, Martin Schrappe, Claudia Rossig, Monika Brüggemann, Guranda Chitadze
Journal: Blood
Blood (2023) 142 (Supplement 1): 595.
https://doi.org/10.1182/blood-2023-186998
Published: 2023
Journal Articles

Venetoclax and Blinatumomab for Adult Patients with Relapsed/Refractory or MRD Positive Ph-Negative B-Precursor ALL: First Results of the GMALL-Bliven Trial

Lars Fransecky, Walter Fiedler, Christoph Röllig, Tim Sauer, Simon Raffel, Winfried Alsdorf, Lisa Heberling, Kumaran Nagarajan, Britta Steer, Philipp Nakov, Björn Steffen, Dorothee Deckbar, Sonja Bendig, Lorenz Bastian, Martin Neumann, Monika Brueggemann, Nicola Goekbuget, Claudia D Baldus
Journal: Blood
Blood (2023) 142 (Supplement 1): 1502.
https://doi.org/10.1182/blood-2023-173937
Published: 2023
Journal Articles

A Novel Fc-Optimized Antibody Drug Conjugate Targeting CD7 As a Therapeutic Strategy in T-Cell Acute Lymphoblastic Leukemia

Carina Lynn Gehlert, Denis Martin Schewe, Katja Klausz, Steffen Krohn, Dorothee Winterberg, Fotini Vogiatzi, Ammelie Svea Boje, Anja Lux, Falk Nimmerjahn, Regina Scherließ, Andreas Humpe, Martin Schrappe, Gunnar Cario, Thomas Valerius, Lars Fransecky, Monika Brüggemann, Claudia D Baldus, Martin Gramatzki, Lennart Lenk, Christian Kellner, Matthias Peipp
Journal: Blood
Blood (2023) 142 (Supplement 1): 4190.
https://doi.org/10.1182/blood-2023-185875
Published: 2023
Journal Articles

Safety and Tolerability of AZD0466 As Monotherapy for Patients with Advanced Hematologic Malignancies. Results from a Phase I/II Trial

Shukaib Arslan, Giovanni Marconi, Giovanni Martinelli, Shaun Fleming, Antonio Curti, Shira N. Dinner, James S Blachly, Matteo Giovanni Della Porta, Ashish Bajel, Tim Sauer, Martina Crysandt, Arnaud Pigneux, Lars Fransecky, Claudia D Baldus, Marina Y. Konopleva, Yotvat Marmor, Shringi Sharma, Nairouz Elgeioushi, Patricia Cheung, Emily Rowe, Ekaterina Jahn, Ting Yu, Jamal Saeh, Raoul Tibes, Fathima Zumla Cader, Nitin Jain
Journal: Blood
Blood (2023) 142 (Supplement 1): 5907.
https://doi.org/10.1182/blood-2023-179168
Published: 2023
Journal Articles

Reshaping MRD Detection Strategies: Next-Generation Sequencing and High DNA Input Identify Previously Missed Measurable Residual Disease in Peripheral Blood of B-Cell Precursor Acute Lmyphoblastic Leukemia

Sonja Bendig, Sandra Bufe, Birgit Fricke, Constantin Proske, Nikos Darzentas, Britta Kehden, Guranda Chitadze, Claudia D Baldus, Michaela Kotrova, Nicola Goekbuget, Monika Brüggemann
Journal: Blood
Blood (2023) 142 (Supplement 1): 4354.
https://doi.org/10.1182/blood-2023-174458
Published: 2023
Journal Articles

Secondary-Type Mutations Do Not Impact the Favorable Outcome of NPM1 -Mutated Acute Myeloid Leukemia Patients - Results from a Large Cohort of Intensively Treated Patients

Marius Bill, Jan-Niklas Eckardt, Christian Rausch, Klaus H Metzeler, Karsten Spiekermann, Sebastian Stasik, Tim Sauer, Sebastian Scholl, Andreas Hochhaus, Martina Crysandt, Tim H. Brümmendorf, Utz Krug, Bernhard Wörmann, Wolfgang Hiddemann, Dennis Görlich, Maria Cristina Sauerland, Björn Steffen, Hermann Einsele, Andreas Neubauer, Andreas Burchert, Kerstin Schaefer-Eckart, Wolfgang E. Berdel, Christoph Schliemann, Stefan W. Krause, Mathias Hanel, Maher Hanoun, Martin Kaufmann, Lars Fransecky, Jan Braess, Leo Ruhnke, Johannes Schetelig, Jan Moritz Middeke, Hubert Serve, Claudia D Baldus, Uwe Platzbecker, Carsten Müller-Tidow, Martin Bornhäuser, Tobias Herold, Christian Thiede, Christoph Röllig
Journal: Blood
Blood (2023) 142 (Supplement 1): 721.
https://doi.org/10.1182/blood-2023-186160
Published: 2023
Journal Articles

Mimicking Clinical Trials with Synthetic Acute Myeloid Leukemia Patients Using Generative Artificial Intelligence

Jan-Niklas Eckardt, Waldemar Hahn, Christoph Röllig, Sebastian Stasik, Uwe Platzbecker, Carsten Müller-Tidow, Hubert Serve, Claudia D Baldus, Christoph Schliemann, Kerstin Schäfer-Eckart, Maher Hanoun, Martin Kaufmann, Andreas Burchert, Christian Thiede, Johannes Schetelig, Martin Bornhäuser, Markus Wolfien, Jan Moritz Middeke
Journal: Blood
Blood (2023) 142 (Supplement 1): 2268.
https://doi.org/10.1182/blood-2023-179817
Published: 2023
Journal Articles

An Open Label Study Comparing Photobiomodulation Therapy to Cryotherapy in Patients at High Risk for Drug-Induced Oral Mucositis

Philipp Nakov, Ruth Lando, Torsten Schroeder, Lasse Jost, Lauritz Miarka, David Baden, Cornelia Baden, Nassim Kakavand, Enrique Restrepo-Salamaca, Alina Kloth, Anca Maria Albici, Laura Jane Kramp, Felix Brachaczek, Julia Feuerborn, Carsten Haack, Claudia Schmalz, Stephanie Busch, Friedrich Stoelzel, Claudia D Baldus, Lars Fransecky
Journal: Blood
Blood (2023) 142 (Supplement 1): 7081.
https://doi.org/10.1182/blood-2023-180110
Published: 2023
Journal Articles

Risk Stratification of Patients with RUNX1- mutated Acute Myeloid Leukemia

Christian Rausch, Roman Hornung, Aarif M. N. Batcha, Maja Rothenberg-Thurley, Stefanos A. Bamopoulos, Vindi Jurinovic, Bianka Ksienzyk, Stephanie Schneider, Annika Maria Dufour, Michaela Neusser, Maria Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E. Berdel, Bernhard J. Woermann, Jan Braess, Wolfgang Hiddemann, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Johannes Schetelig, Moritz Middeke, Sebastian Stasik, Katharina Egger-Heidrich, Christoph Röllig, Martin Bornhäuser, Christian Thiede, Claudia D Baldus, Carsten Müller-Tidow, Uwe Platzbecker, Hubert Serve, Wendy Stock, Geoffrey L Uy, John C. Byrd, Deedra Nicolet, Ann-Kathrin Eisfeld, Ulrich Mansmann, Karsten Spiekermann, Klaus H Metzeler, Tobias Herold
Journal: Blood
Blood (2023) 142 (Supplement 1): 2934.
https://doi.org/10.1182/blood-2023-174059
Published: 2023
Journal Articles

Venetoclax Plus High-Dose Cytarabine and Mitoxantrone (HAM-Ven) As Salvage Treatment for Relapsed/Refractory AML: Updated Results of the Phase-I/II SAL Relax Trial

Leo Ruhnke, Christoph Schliemann, Jan-Henrik Mikesch, Matthias Stelljes, Lars Fransecky, Björn Steffen, Martin Kaufmann, Andreas Burchert, Andreas Rank, Maher Hanoun, Alexander Höllein, Sabrina Kraus, Mathias Hänel, Kerstin Schäfer-Eckart, Annett Haake, Frank Fiebig, Sven Zukunft, Jan Moritz Middeke, Désirée Kunadt, Johannes Schetelig, Malte von Bonin, Maximilian Alexander Röhnert, Uta Oelschlägel, Friedrich Stölzel, Claudia D Baldus, Hubert Serve, Martin Wermke, Martin Bornhäuser, Christoph Röllig
Journal: Blood
Blood (2023) 142 (Supplement 1): 160.
https://doi.org/10.1182/blood-2023-184445
Published: 2023
Journal Articles

Pseudoprogression As Adverse Event of Chimeric Antigen Receptor T Cell Therapy

Torsten Schroeder, Tjark Martens, Guranda Chitadze, Fatih Yalcin, Heiko Trautmann, Monika Brüggemann, Christine Heinen, Philipp Nakov, Anca Maria Albici, Nicolas Spath, Lukas Sprenger, Laura Jane Kramp, Matthias Ritgen, Dominique Wellnitz, Maciej Simon, Sebastian Lippross, Ingram Iaccarino, Wolfram Klapper, Lars Fransecky, Thomas Valerius, Natalie Schub, Christiane Pott, Claudia D Baldus, Friedrich Stoelzel
Journal: Blood
Blood (2023) 142 (Supplement 1): 6935.
https://doi.org/10.1182/blood-2023-189047
Published: 2023
Journal Articles

Molecular Subtypes in BCR::ABL1 -Positive ALL Are Defined By Cellular Origins and Cooperating Genomic Events

Lorenz Bastian, Thomas Beder, Malwine Barz, Sonja Bendig, Lorenz Bartsch, Wencke Walter, Nadine Wolgast, Björn Brändl, Christian Rohrandt, Björn-Thore Hansen, Alina M. Hartmann, Katharina Iben, Miriam Bultmann, Johannes Zimmermann, Michael Wittig, Guranda Chitadze, Martin Neumann, Folker Schneller, Walter Fiedler, Björn Steffen, Matthias Stelljes, Christoph Faul, Stefan Schwartz, Franz-Josef Müller, Gunnar Cario, Lana Harder, Claudia Haferlach, Heike Pfeifer, Nicola Goekbuget, Monika Brüggemann, Claudia D Baldus
Journal: Blood
Blood (2023) 142 (Supplement 1): 843.
https://doi.org/10.1182/blood-2023-187315
Published: 2023
Journal Articles

Overlapping features of therapy-related and de novo NPM1 -mutated AML

Clinical Trials & Observations
Jad Othman, Manja Meggendorfer, Enrico Tiacci, Christian Thiede, Richard Schlenk, Richard Dillon, Sebastian Stasik, Alessandra Venanzi, Sarah Bertoli, Eric Delabesse, Pierre-Yves Dumas, Arnaud Pigneux, Audrey Bidet, Amanda F. Gilkes, Ian Thomas, Maria Teresa Voso, Alessandro Rambaldi, Lorenzo Brunetti, Vincenzo M. Perriello, Vibeke Andresen, Bjorn T. Gjertsen, Maria Paola Martelli, Christian Récher, Christoph Röllig, Martin Bornhäuser, Hubert Serve, Carsten Müller-Tidow, Claudia D. Baldus, Tortsten Haferlach, Nigel Russell, Brunangelo Falini
Journal: Blood
Blood (2023) 141 (15): 1846–1857.
https://doi.org/10.1182/blood.2022018108
Published: 2023
Includes: Supplemental data
Journal Articles

Somatic TP53 mutations are preleukemic events in acute lymphoblastic leukemia

Guranda Chitadze, Anna Stengel, Cathrin John-Klaua, Julien Bruckmüller, Heiko Trautmann, Michaela Kotrova, Franziska Darzentas, Miriam Kelm, Karol Pal, Nikos Darzentas, Lorenz Bastian, Britta Kehden, Wiebke Wessels, Aeint-Steffen Ströh, Hans-Heinrich Oberg, Philipp M. Altrock, Constance Baer, Manja Meggendorfer, Nicola Gökbuget, Claudia D. Baldus, Claudia Haferlach, Monika Brüggemann
Journal: Blood
Blood (2023) 141 (13): 1640–1644.
https://doi.org/10.1182/blood.2022017249
Published: 2023
Includes: Supplemental data
Journal Articles

Venetoclax Plus High-Dose Cytarabine and Mitoxantrone As Feasible and Effective Novel Treatment for Relapsed AML: Results of the Phase-I SAL Relax Trial

Christoph Röllig, Lars Fransecky, Maher Hanoun, Björn Steffen, Sabrina Kraus, Christoph Schliemann, Annett Haake, Frank Fiebig, Sven Zukunft, Nael Alakel, Jan Moritz Middeke, Martin Bornhaeuser, Friedrich Stoelzel, Johannes Schetelig, Leo Ruhnke, Michael Kramer, Malte Von Bonin, Maximilian Alexander Röhnert, Uta Oelschlägel, Claudia D. Baldus, Hubert Serve, Martin Wermke
Journal: Blood
Blood (2022) 140 (Supplement 1): 3327–3328.
https://doi.org/10.1182/blood-2022-159897
Published: 2022
Journal Articles

CD19-CAR-T Cells Are Effective and Safe Treatment of Post-Transplant Relapse in Pediatric and Young Adult Patients with B-Lineage ALL: Real-World Data from Germany

Peter Bader, Claudia Rossig, Martin Hutter, Francis A. Ayuk, Claudia D. Baldus, Veit L Buecklein, Halvard Bonig, Gunnar Cario, Hermann Einsele, Udo Holtick, Christian Koenecke, Annette Künkele, Roland Meisel, Fabian Mueller, Ingo Müller, Olaf Penack, Eva Rettinger, Martin G. Sauer, Paul-Gerhardt Schlegel, Jan Soerensen, Arend von Stackelberg, Tobias Feuchtinger, Andrea Jarisch
Journal: Blood
Blood (2022) 140 (Supplement 1): 10407–10409.
https://doi.org/10.1182/blood-2022-156775
Published: 2022
Journal Articles

Single Versus Double Induction with "7+3" Containing 60 Versus 90 Mg Daunorubicin for Newly Diagnosed AML: Results from the Randomized Controlled SAL Dauno-Double Trial

Christoph Röllig, Björn Steffen, Christoph Schliemann, Jan-Henrik Mikesch, Nael Alakel, Regina Herbst, Mathias Haenel, Richard Noppeney, Maher Hanoun, Martin Kaufmann, Zdenek Racil, Kerstin Schäfer-Eckart, Tim Sauer, Andreas Neubauer, Claudia D. Baldus, Jolana Mertova, Edgar Jost, Dirk Niemann, Jan Novak, Stefan W. Krause, Sebastian Scholl, Andreas Hochhaus, Gerhard Held, Tomáš Szotkowski, Christoph Schmid, Andreas Rank, Lars Fransecky, Michael Kramer, Frank Fiebig, Annett Haake, Friedrich Stoelzel, Johannes Schetelig, Jan Moritz Middeke, Uwe Platzbecker, Christian Thiede, Carsten Müller-Tidow, Wolfgang E. Berdel, Hubert Serve, Gerhard Ehninger, Jiří Mayer, Martin Bornhaeuser
Journal: Blood
Blood (2022) 140 (Supplement 1): 523–525.
https://doi.org/10.1182/blood-2022-157126
Published: 2022