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Martin Gramatzki
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Journal Articles

Preclinical Development of a Novel Humanized and Fc-Engineered Antibody-Drug Conjugate for the Therapy of T-Cell Acute Lymphoblastic Leukemia

Steffen Krohn, Carina Lynn Gehlert, Dorothee Winterberg, Alexander Jochimsen, Ammelie Svea Boje, Natalie Baum, Claudia D Baldus, Monika Brüggemann, Gunnar Cario, Martin Schrappe, Lennart Lenk, Martin Gramatzki, Katja Klausz, Christian Kellner, Matthias Peipp
Journal: Blood
Blood (2024) 144 (Supplement 1): 4173.
https://doi.org/10.1182/blood-2024-207737
Published: 2024
Journal Articles

A Novel Platform Technology for the Development of NK Cell-Based Cellular Immunotherapies

Ammelie Svea Boje, Anna Langner, Carina Lynn Gehlert, Carmen Reitinger, Falk Nimmerjahn, Eva Maria Murga Penas, Sonja Bendig, Guranda Chitadze, Monika Brüggemann, Katharina Diemer, Alexander Jochimsen, Dorothee Winterberg, Natalie Baum, Steffen Krohn, Thomas Valerius, Friedrich Stölzel, Martin Gramatzki, Katja Klausz, Christian Kellner, Matthias Peipp
Journal: Blood
Blood (2024) 144 (Supplement 1): 914.
https://doi.org/10.1182/blood-2024-210243
Published: 2024
Journal Articles

A Novel Fc-Optimized Antibody Drug Conjugate Targeting CD7 As a Therapeutic Strategy in T-Cell Acute Lymphoblastic Leukemia

Carina Lynn Gehlert, Denis Martin Schewe, Katja Klausz, Steffen Krohn, Dorothee Winterberg, Fotini Vogiatzi, Ammelie Svea Boje, Anja Lux, Falk Nimmerjahn, Regina Scherließ, Andreas Humpe, Martin Schrappe, Gunnar Cario, Thomas Valerius, Lars Fransecky, Monika Brüggemann, Claudia D Baldus, Martin Gramatzki, Lennart Lenk, Christian Kellner, Matthias Peipp
Journal: Blood
Blood (2023) 142 (Supplement 1): 4190.
https://doi.org/10.1182/blood-2023-185875
Published: 2023
Journal Articles

Long-Term Outcome of a Prospective Randomized Trial Comparing Continuous Lenalidomide/Dexamethasone with Lenalidomide/Dexamethasone Induction, MEL140 with Autologous Blood Stem Cell Transplantation and Single Agent Lenalidomide Maintenance in Patients of Age 60-75 Years with Newly Diagnosed Multiple Myeloma

Christian Straka, Kerstin Schaefer-Eckart, Bernd Hertenstein, Florian Bassermann, Hans Salwender, Christian Langer, Jan Krönke, Miriam Kull, Georgia Schilling, Aneta Schieferdecker, Monika Engelhardt, Stefan Knop, Julia Reusch, Wolf Roesler, Bernd Metzner, Holger Hebart, Albrecht Reichle, Matthias Grube, Norbert Frickhofen, Christian Gerecke, Stephan Fuhrmann, Wolfram Jung, Martin Gramatzki, Thomas Decker, Tobias Dechow, Jochen Greiner, Tim H. Brümmendorf, Juliana Ababei, Ivana von Metzler, Ralph Naumann, Elisabeth Fritz, Marcus Hentrich, Peter Bojko, Thomas Kubin, Christian Schmidt, Martin Kaufmann, Burkhard Schmidt, Axel Hinke, Hermann Einsele
Journal: Blood
Blood (2022) 140 (Supplement 1): 287–288.
https://doi.org/10.1182/blood-2022-159357
Published: 2022
Journal Articles

Blocking the Don't Eat Me Signal (CD47-SIRPα Axis) to Improve Antibody-Based Immunotherapy of Multiple Myeloma

Katja Klausz, Carina Lynn Gehlert, Ammelie Svea Boje, Marta Lustig, Steffen Krohn, Syeda Maliha Ahmed, Christian Kellner, Thomas Valerius, Lenka Besse, Andrej Besse, Christoph Driessen, Martin Gramatzki, Matthias Peipp
Journal: Blood
Blood (2021) 138 (Supplement 1): 2684.
https://doi.org/10.1182/blood-2021-152208
Published: 2021
Journal Articles

Patterns of Renal Recovery and Toxicity with Novel Agent-Based Induction Triplets in Newly Diagnosed Multiple Myeloma - an Analysis of Two Prospective Studies By the German DSMM Myeloma Study Group

Friederike Bachmann, MD, Swantje Held, Monika Engelhardt, MD, Christian Langer, MD, Denise Wolleschak, Janik Fleissner, Lars-Olof Mügge, MD, Heinz Duerk, MD PhD, Martin Schreder, MD, Kerstin Schaefer-Eckart, MD, Igor-Wolfgang Blau, MD PhD, Martin Gramatzki, MD, Peter Liebisch, MD, Albrecht Reichle, MD, Ivana Metzler, MD, Florian Bassermann, MD PhD, Bernd Metzner, MD PhD, Christoph Röllig, MD MSC, Bernd Hertenstein, Tobias Dechow, Wolfram Jung, MD, Helmut Ostermann, MD, Holger Hebart, Georg Maschmeyer, MD, Hans Jürgen Salwender, MD, Marie von Lilienfeld-Toal, MD, Kai-Uwe Eckardt, MD, Christian Straka, MD PhD, Hermann Einsele, MD, Stefan Knop
Journal: Blood
Blood (2019) 134 (Supplement_1): 1840.
https://doi.org/10.1182/blood-2019-125235
Published: 2019
Journal Articles

Autologous and Allogeneic Hematopoietic Stem-Cell Transplantation for Patients with Richter's Syndrome: A Large Series from the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation

Olivier Tournilhac, MD PhD, Romain Guièze, MD PhD, Dirk-Jan Eikema, Nienke Zinger, Henrik Sengeloev, MD DMSc, Jakob R. Passweg, MD, Bendt Nielsen, Xavier Poire, Jenny Byrne, MD PhD, Martin Gramatzki, MD, Jürgen Finke, MD, Jan J Cornelissen, MD PhD, D Blaise, Emmanouil Nikolousis, MDPhDMRCP FRCPath, Patrice Chevallier, MD, Gwendolyn Van Gorkom, Mark Ringhoffer, MD, Nicola Mordini, Liesbeth C. de Wreede, PhD, Patrick John Hayden, BA, Michel van Gelder, MD PhD, Ibrahim Yakoub-Agha, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2053.
https://doi.org/10.1182/blood-2019-129949
Published: 2019
Journal Articles

The Role of Donor Selection for a Second Allogeneic Stem Cell Transplantation in Patients with AML Relapsing after a First Transplant; A Study on Behalf of the Acute Leukemia Working Party of EBMT

Avichai Shimoni, MD, Myriam Labopin, MD, Jürgen Finke, MD, Fabio Ciceri, MD, Eric Deconinck, MD PhD, Nicolaus Kröger, MD, Martin Gramatzki, MD, Matthias Stelljes, MD, Didier Blaise, Friedrich Stoelzel, Patrice Chevallier, MD, Ernst Holler, MD PhD, Nathalie Fegueux, Mohamad Mohty, MD PhD, Arnon Nagler, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3460.
https://doi.org/10.1182/blood-2018-99-110614
Published: 2018
Journal Articles

Targeting the Glyco-Antigen CD75s with the Tetravalent, Fc-Engineered Antibody 'Ebu-141 Tetra' Induces Potent Killing of B Cell Lymphoma and Plasma Cell Tumors

Katja Klausz, PhD, Amir Karimzadeh-Tabrizi, Malena Buck, Steffen Krohn, Anna-Kathrin Otte, PhD, Christian Kellner, PhD, Giorgio Alberto Croci, MD, Wolfram Klapper, MD, Matthias Peipp, PhD, Martin Gramatzki, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4178.
https://doi.org/10.1182/blood-2018-99-118068
Published: 2018
Journal Articles

Preclinical Characterization of AFM26, a Novel B Cell Maturation Antigen (BCMA)-Directed Tetravalent Bispecific Antibody for High Affinity Retargeting of NK Cells Against Myeloma

Thorsten Ross, PhD, Uwe Reusch, PhD, Susanne Wingert, PhD, Torsten Haneke, PhD, Katja Klausz, PhD, Anna-Kathrin Otte, PhD, Natalie Schub, MD, Stefan Knackmuss, PhD, Thomas Müller, Kristina Ellwanger, PhD, Ivica Fucek, Ute Schniegler-Mattox, Joachim Koch, PhD, Thomas Valerius, MD, Martin Gramatzki, MD, Matthias Peipp, PhD, Michael Tesar, PhD, Erich Rajkovic, PhD MBA, Martin Treder, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1927.
https://doi.org/10.1182/blood-2018-99-118970
Published: 2018
Journal Articles

Lenalidomide, Adriamycin and Dexamethasone (RAD) Versus Bortezomib, Lenalidomide and Dexamethasone (VRD) in Newly Diagnosed Multiple Myeloma (MM) - Post-Induction Response and MRD Results By Flow Cytometry and NGS from a Phase 3 Randomized Controlled Clinical Trial (RCT)

Thomas Stübig, MD, Christian Langer, MD, Monika Engelhardt, MD, Lars-Olof Mügge, MD, Florian Bassermann, MD PhD, Martin Schreder, MD, Kerstin Schäfer-Eckart, MD, Igor Wolfgang Blau, Denise Wolleschak, Albrecht Reichle, MD, Ivana Metzler, MD, Bernd Metzner, MDPhD, Christoph Rollig, MD MSC, Bernd Hertenstein, MD, Heinz Dürk, Harald Biersack, MD, Helge Menzel, MD, Tobias Dechow, Jan Schleicher, Martin Gramatzki, MD, Tim H. Brümmendorf, MD, Stephan Fuhrmann, Max Bittrich, MD, Franziska Appelt, Martina Müller, Jan Krönke, MD, Julia Reusch, Christian Schmidt, MD, Monika Brüggemann, MD, Swantje Held, Stefan Knop, Hermann Einsele, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1979.
https://doi.org/10.1182/blood-2018-99-116067
Published: 2018
Journal Articles

MOR202 with Low-Dose Dexamethasone (Dex) or Pomalidomide/Dex or Lenalidomide/Dex in Relapsed or Refractory Multiple Myeloma (RRMM): Primary Analysis of a Phase I/IIa, Multicenter, Dose-Escalation Study

Marc S Raab, MD PhD, Manik Chatterjee, MD, Hartmut Goldschmidt, MD, Hermine Agis, MD, Igor Blau, MD PhD, Hermann Einsele, MD, Monika Engelhardt, MD, Barbara Ferstl, MD, Martin Gramatzki, MD, Christoph Rollig, MD MSC, Katja Weisel, MD, Tiantom Jarutat, MD, Dominika Weinelt, MD, Mark Winderlich, PhD, Christian Peschel, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 153.
https://doi.org/10.1182/blood-2018-153
Published: 2018
Journal Articles

CD75s Represents a Therapeutic Target for Antibody-Based Immunotherapy of B Cell Lymphoma and Multiple Myeloma

Katja Klausz, PhD, Malena Buck, Steffen Krohn, Renate Burger, PhD, Christian Kellner, PhD, Martin Gramatzki, MD, Matthias Peipp, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1810.
https://doi.org/10.1182/blood.V130.Suppl_1.1810.1810
Published: 2017
Journal Articles

Immune Reconstitution after Allogeneic Stem Cell Transplantation - a Systematic Single Center Survey

Anna Sophie Hartjen, Andreas Krumbholz, MD, Florian Thieme, PhD, Natalie Schub, MD, Andreas Humpe, MD, Michaela Kotrova, Monika Brüggemann, MD, Martin Gramatzki, MD, Andreas Guenther, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5490.
https://doi.org/10.1182/blood.V130.Suppl_1.5490.5490
Published: 2017
Journal Articles

An Fc-engineered CD19 antibody eradicates MRD in patient-derived MLL -rearranged acute lymphoblastic leukemia xenografts

Denis M. Schewe, Ameera Alsadeq, Cornelia Sattler, Lennart Lenk, Fotini Vogiatzi, Gunnar Cario, Simon Vieth, Thomas Valerius, Sophia Rosskopf, Fabian Meyersieck, Julia Alten, Martin Schrappe, Martin Gramatzki, Matthias Peipp, Christian Kellner
Journal: Blood
Blood (2017) 130 (13): 1543–1552.
https://doi.org/10.1182/blood-2017-01-764316
Published: 2017
Includes: Supplemental data
Journal Articles

Matching for the MICA-129 polymorphism is beneficial in unrelated hematopoietic stem cell transplantation

Clinical Trials & Observations
Daniel Fuerst, Christine Neuchel, Dietger Niederwieser, Donald Bunjes, Martin Gramatzki, Eva Wagner, Gerald Wulf, Bertram Glass, Michael Pfreundschuh, Hermann Einsele, Renate Arnold, Gernot Stuhler, Kerstin Schaefer-Eckart, Sebastian Freitag, Jochen Casper, Martin Kaufmann, Mohammed Wattad, Bernd Hertenstein, Stefan Klein, Mark Ringhoffer, Daphne Mytilineos, Chrysanthi Tsamadou, Carlheinz Mueller, Hubert Schrezenmeier, Joannis Mytilineos
Journal: Blood
Blood (2016) 128 (26): 3169–3176.
https://doi.org/10.1182/blood-2016-05-716357
Published: 2016
Journal Articles

A Phase I/IIa Study of the CD38 Antibody MOR202 Alone and in Combination with Pomalidomide or Lenalidomide in Patients with Relapsed or Refractory Multiple Myeloma

Marc S. Raab, MD, Manik Chatterjee, MD, Hartmut Goldschmidt, MD, Hermine Agis, MD, Igor Blau, Hermann Einsele, MD, Monika Engelhardt, MD PhD, Barbara Ferstl, MD, Martin Gramatzki, MD, Christoph Röllig, MD, Katja Weisel, MD, Tiantom Jarutat, MD, Dominika Weinelt, MD, Jan Endell, PhD, Rainer Boxhammer, PhD, Christian Peschel, MD
Journal: Blood
Blood (2016) 128 (22): 1152.
https://doi.org/10.1182/blood.V128.22.1152.1152
Published: 2016
Journal Articles

Carfilzomib in Combination with Bendamustine and Dexamethasone (CBd) in Relapsed and/or Refractory Patients with Multiple Myeloma: The Phase I/II EMN09 Study

Martin Gramatzki, Andreas Günther, Massimo Offidani, MD, Monika Engelhardt, Paolo Corradini, Silvia Gentili, Vittorio Montefusco, Francesca Patriarca, MD, Natalie Schub, Hermann Einsele, MD, Pieter Sonneveld, Antonio Palumbo, MD, Francesca Gay
Journal: Blood
Blood (2016) 128 (22): 3334.
https://doi.org/10.1182/blood.V128.22.3334.3334
Published: 2016
Journal Articles

Identification of Baseline Characteristics That Predict Good Outcome of Allogeneic Hematopoietic Cell Transplantation in Young Chronic Lymphocytic Leukemia Patients - a Retrospective Analysis from the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation.

Michel van Gelder, MD PhD, Dimitris Ziagkos, Liesbeth C de Wreede, PhD, Anja van Biezen, Peter Dreger, MD, Martin Gramatzki, MD, Matthias Stelljes, Niels Smedegaard Andersen, Nicolaas PM Schaap, MD, Antonin Vitek, Dietrich Beelen, MD, Liisa Volin, MD PhD, Jürgen Finke, Jakob R Passweg, MD, Arnold Ganser, Maciej J Machaczka, MD, Julio Delgado, MD, William Krüger, Edgar Faber, Gerard Socie, Pavel Jindra, MD PhD, Boris V Afanasyev, Professor, Matthias Theobald, MD PhD, Yves Chalandon, MD, Anja Henseler, Stefan O. Schoenland, MD, Kroger Nicolaus, Johannes Schetelig, MD MSc
Journal: Blood
Blood (2016) 128 (22): 522.
https://doi.org/10.1182/blood.V128.22.522.522
Published: 2016
Journal Articles

Bortezomib Consolidation Following Autologous Transplant Equalizes the Outcome for Older Patients with Less Intensive Pretreatment Compared to Younger Patients with Newly Diagnosed Multiple Myeloma

Christian Straka, MD, Stefan Knop, MD, Martin Vogel, MD PhD, Jurgen Müller, Dipl. Stat., Martin Kropff, MD, Bernd Metzner, MD, Christian Langer, MD, Herbert Sayer, MD, Wolfram Jung, MD, Heinz Dürk, MD PhD, Hans-Juergen Salwender, MD, Hannes Wandt, MD, PhD, Florian Bassermann, MD, Martin Gramatzki, MD, Wolf Rösler, MD, Hans-Heinrich Wolf, MD, Wolfram Brugger, MD PhD, Monika Engelhardt, MD, Thomas Fischer, MD, Peter Liebisch, MD, Hermann Einsele, MD
Journal: Blood
Blood (2016) 128 (22): 516.
https://doi.org/10.1182/blood.V128.22.516.516
Published: 2016