1-20 of 108
Hubert Schrezenmeier
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Adding eltrombopag to immunosuppressive treatment with cyclosporine as front-line therapy for moderate aplastic anemia improves trilineage hematologic response: One-year analysis of the randomised, placebo-controlled, double-blind Phase III trial eltrombopag for moderate aplastic anemia (EMAA Trial)

Free
Britta Hoechsmann, Philippe Schafhausen, Fabian Beier, Michael Heuser, Joerg Westermann, Beatrice Drexler, Alexander Röth, Mathias Hänel, Flore Sicre-de-Fontbrune, Astrid Marx-Hofmann, Antonia Beitzen-Heineke, Jens Panse, Felicitas R Thol, Sixten Koerper, Tim H. Brummendorf, Hubert Schrezenmeier
Journal: Blood
Blood (2025) 146 (Supplement 1): 980.
https://doi.org/10.1182/blood-2025-980
Published: 2025
Journal Articles

Danicopan add-on therapy demonstrates positive efficacy and safety outcomes in advanced age adults with paroxysmal nocturnal hemoglobinuria and clinically significant extravascular hemolysis: A sub-analysis of the phase 3 ALPHA trial

Free
Austin Kulasekararaj, Morag Griffin, Robert Brodsky, Jun-ichi Nishimura, Christopher Patriquin, Hubert Schrezenmeier, Wilma Barcellini, Anna Gaya, Yogesh Patel, Ying Tang, Gleb Filippov, Mohammed Mahdi, Flore Sicre-de-Fontbrune, Jong Wook Lee
Journal: Blood
Blood (2025) 146 (Supplement 1): 949.
https://doi.org/10.1182/blood-2025-949
Published: 2025
Journal Articles

The 2-year efficacy and safety of iptacopan monotherapy in patients with paroxysmal nocturnal hemoglobinuria with a history of aplastic anemia on concomitant immunosuppressive therapy who entered the roll-over extension program

Free
Regis Peffault De Latour, Carlos de Castro, Anna Gaya, Morag Griffin, Bing Han, Austin Kulasekararaj, Jaroslaw Maciejewski, Bhumika Patel, Alexander Röth, Phillip Scheinberg, Hubert Schrezenmeier, Yasutaka Ueda, Tim Costigan, Marion Dahlke, Philippe Ferber, Rajeshri Karki, Luca Monaco, Silvia Sanz, Antonio Risitano
Journal: Blood
Blood (2025) 146 (Supplement 1): 4978.
https://doi.org/10.1182/blood-2025-4978
Published: 2025
Journal Articles

Real-world analysis of ravulizumab safety and effectiveness in advanced age patients with paroxysmal nocturnal hemoglobinuria: Insights from the international PNH registry

Free
Shreyans Gandhi, Ami Patel, Alix Augustin-Wright, Hubert Schrezenmeier, Philippe Gustovic, Jesse Metzger, Yasutaka Ueda, Richard Kelly
Journal: Blood
Blood (2025) 146 (Supplement 1): 6238.
https://doi.org/10.1182/blood-2025-6238
Published: 2025
Journal Articles

Long-term efficacy and safety of danicopan as add-on therapy to ravulizumab or eculizumab in PNH with significant EVH

Open Access
Clinical Trials & Observations
Austin Kulasekararaj, Morag Griffin, Caroline Piatek, Jamile Shammo, Jun-ichi Nishimura, Christopher Patriquin, Hubert Schrezenmeier, Wilma Barcellini, Jens Panse, Anna Gaya, Yogesh Patel, Peng Liu, Gleb Filippov, Flore Sicre de Fontbrune, Antonio Risitano, Jong Wook Lee
Journal: Blood
Blood (2025) 145 (8): 811–822.
https://doi.org/10.1182/blood.2024026299
Published: 2025
Includes: Supplemental data
Journal Articles

Monotherapy Treatment with Zaltenibart (OMS906), an Alternative Pathway Masp-3 Inhibitor, Improved Key Hematologic Parameters in Patients with PNH with a Suboptimal Response to Ravulizumab: Interim Results from a Phase 2 Proof-of-Concept Study

Free
Morag Griffin, Richard J. Kelly, Mathilde Gavillet, Petra Muus, Britta Hoechsmann, W. Jason Cummings, John Efthimiou, William Pullman, Hubert Schrezenmeier, Jens Panse
Journal: Blood
Blood (2024) 144 (Supplement 1): 4072.
https://doi.org/10.1182/blood-2024-205866
Published: 2024
Journal Articles

Breakthrough Hemolysis Events in Patients with Paroxysmal Nocturnal Hemoglobinuria: Data from Danicopan and Pegcetacoplan Trials

Free
Hubert Schrezenmeier, Mohammed Mahdi, Christoph Gasteyger, Cecile De Coster
Journal: Blood
Blood (2024) 144 (Supplement 1): 2694.
https://doi.org/10.1182/blood-2024-203195
Published: 2024
Journal Articles

Danicopan As Add-on Therapy to Ravulizumab or Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria: Long-Term Patient-Reported Outcomes from the Phase 3 ALPHA Trial

Free
Caroline Piatek, Jong Wook Lee, Morag Griffin, Jun-Ichi Nishimura, Christopher Patriquin, Hubert Schrezenmeier, Wilma Barcellini, Jamile Shammo, Anna Gaya, Mohammed Mahdi, Peng Liu, Karl-Johan Myren, Andrew Messali, Flore Sicre de Fontbrune, Jens Panse, Austin G. Kulasekararaj
Journal: Blood
Blood (2024) 144 (Supplement 1): 2692.
https://doi.org/10.1182/blood-2024-199506
Published: 2024
Journal Articles

Ravulizumab in Pregnant Women with Paroxysmal Nocturnal Hemoglobinuria (PNH) - Favourable Experience from a Retrospective Case Series

Free
Britta Hoechsmann, Wilhelm Leopold, Ariane Schneider, Sixten Koerper, Ursula Kalhammer, Hubert Schrezenmeier
Journal: Blood
Blood (2024) 144 (Supplement 1): 5251.
https://doi.org/10.1182/blood-2024-209857
Published: 2024
Journal Articles

Impact of Various Combinations of Potentially Immunogenic Therapeutics on the T Cell Response in Acute Myeloid Leukemia

Free
Jochen Greiner, Patrick J Schuler, Hubert Schrezenmeier, Susanne Hofmann, Marlies Götz
Journal: Blood
Blood (2024) 144 (Supplement 1): 5792.
https://doi.org/10.1182/blood-2024-205110
Published: 2024
Journal Articles

Factor B Inhibition with Oral Iptacopan Monotherapy Demonstrates Sustained Long-Term Efficacy and Safety in Anti-C5-Treated Patients (pts) with Paroxysmal Nocturnal Hemoglobinuria (PNH) and Persistent Anemia: Final 48-Week Results from the Multicenter, Phase III APPLY-PNH Trial

Free
Antonio M Risitano, Austin Kulasekararaj, Alexander Roeth, Phillip Scheinberg, Yasutaka Ueda, Carlos de Castro, Eros Di Bona, Morag Griffin, Saskia MC Langemeijer, Hubert Schrezenmeier, Wilma Barcellini, Vitor AQ Mauad, Jens Panse, Philippe Schafhausen, Suzanne Tavitian, Eloise Beggiato, Anna Gaya, Wei-Han Huang, Toshio Kitawaki, Abdullah Kutlar, Jaroslaw P. Maciejewski, Rosario Notaro, Vinod Pullarkat, Jörg Schubert, Louis Terriou, Michihiro Uchiyama, Flore Sicre De Fontbrune, Camilla Frieri, Ferras Alashkar, Shreyans Gandhi, Rakesh Kumar, Christine Thorburn, Samopriyo Maitra, Susan Solar-Yohay, Tomasz Lawniczek, Marion Dahlke, Régis Peffault De Latour
Journal: Blood
Blood (2023) 142 (Supplement 1): 571.
https://doi.org/10.1182/blood-2023-180780
Published: 2023
Journal Articles

Patient-Reported Outcomes (PROs) in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Treated with Crovalimab and Eculizumab: Results from the Phase III Randomized COMMODORE 2 and COMMODORE 1 Trials

Free
Jens Panse, Jaroslav Cermak, Olena Kyselova, Akihiko Gotoh, Fahri Sahin, Hubert Schrezenmeier, Alice C. Chang, Brittany Gentile, Marianne Uguen, Bing Han
Journal: Blood
Blood (2023) 142 (Supplement 1): 4090.
https://doi.org/10.1182/blood-2023-177584
Published: 2023
Journal Articles

Real-World Data Suggest Effectiveness of Allogeneic Mesenchymal Stromal (MSC-FFM) Cells in Ruxolitinib-Refractory Acute Graft-Versus-Host Disease

Free
Peter Bader, Mareike Verbeek, Peter Herhaus, Lavinia Pachzelt, Gernot Beutel, Christoph Schmid, Nadine Müller, Gesine Bug, Arend von Stackelberg, Johanna Tischer, Francis A. Ayuk, Gerald G. Wulf, Lisa-Marie Pfeffermann, Bernd Jahrsdörfer, Hubert Schrezenmeier, Selim Kuci, Zyrafete Kuci, Anke Zens, Michael Tribanek, Robert Zeiser, Sabine Huenecke, Halvard Bonig
Journal: Blood
Blood (2023) 142 (Supplement 1): 4927.
https://doi.org/10.1182/blood-2023-174492
Published: 2023
Journal Articles

Ravulizumab Provides Durable Control of Intravascular Hemolysis and Improves Survival in Patients with Paroxysmal Nocturnal Hemoglobinuria: Long-Term Follow-up of Study 301 and Comparisons with Patients of the International PNH Registry

Free
Austin Kulasekararaj, Hubert Schrezenmeier, Kensuke Usuki, Aleksander Kulagin, Sandra Fatima Gualandro, Rosario Notaro, Masayo Ogawa, Ji Yu, Ami Patel, Yogesh Patel, Wolfgang Füreder, Regis Peffault De Latour, Jong-Wook Lee
Journal: Blood
Blood (2023) 142 (Supplement 1): 2714.
https://doi.org/10.1182/blood-2023-189150
Published: 2023
Journal Articles

Danicopan As Add-on Therapy to Ravulizumab or Eculizumab Versus Placebo in Patients with Paroxysmal Nocturnal Hemoglobinuria and Clinically Significant Extravascular Hemolysis: Phase 3 Long-Term Data

Free
Austin Kulasekararaj, Morag Griffin, Caroline I Piatek, Jamile Shammo, Jun-Ichi Nishimura, Christopher J. Patriquin, Hubert Schrezenmeier, Anna Gaya, Yogesh Patel, Peng Liu, Gleb Filippov, Flore Sicre De Fontbrune, Antonio M Risitano, Jong-Wook Lee
Journal: Blood
Blood (2023) 142 (Supplement 1): 576.
https://doi.org/10.1182/blood-2023-189863
Published: 2023
Journal Articles

Patient-Reported Outcomes: Danicopan As Add-on Therapy to Ravulizumab or Eculizumab Versus Placebo in Patients with Paroxysmal Nocturnal Hemoglobinuria and Clinically Significant Extravascular Hemolysis

Free
Caroline I Piatek, Jong-Wook Lee, Morag Griffin, Jun-Ichi Nishimura, Christopher J. Patriquin, Hubert Schrezenmeier, Wilma Barcellini, Jamile Shammo, Anna Gaya, Yogesh Patel, Peng Liu, Karl-Johan Myrén, Flore Sicre De Fontbrune, Jens Panse, Austin Kulasekararaj
Journal: Blood
Blood (2023) 142 (Supplement 1): 1346.
https://doi.org/10.1182/blood-2023-190015
Published: 2023
Journal Articles

Oral Monotherapy with Iptacopan, a Proximal Complement Inhibitor of Factor B, Has Superior Efficacy to Intravenous Terminal Complement Inhibition with Standard of Care Eculizumab or Ravulizumab and Favorable Safety in Patients with Paroxysmal Nocturnal Hemoglobinuria and Residual Anemia: Results from the Randomized, Active-Comparator-Controlled, Open-Label, Multicenter, Phase III Apply-PNH Study

Free
Regis Peffault de Latour, Alexander Roeth, Austin Kulasekararaj, Phillip Scheinberg, Yasutaka Ueda, Carlos M de Castro, Eros Di Bona, Hubert Schrezenmeier, Saskia MC Langemeijer, Wilma Barcellini, Suzanne Tavitian, Jens Panse, Philippe Schafhausen, Vitor AQ Mauad, Cecile Kerloeguen, Rafael Levitch, Rakesh Kumar, Christine Thorburn, Samopriyo Maitra, Marion Dahlke, Antonio M Risitano
Journal: Blood
Blood (2022) 140 (Supplement 2): LBA-2.
https://doi.org/10.1182/blood-2022-171469
Published: 2022
Journal Articles

Monitoring the in-Vivo Expansion and Persistence of CAR-T Cells As a Tool to Help Decision Making in Patients with Aggressive B-Cell Lymphoma

Free
Daniel Fürst, Christine Neuchel, Adela Neagoie, Elisa Amann, Immanuel Rode, Angela Krauss, Hubert Schrezenmeier, Verena Wais, Hartmut Döhner, Andreas Viardot, Elisa Sala
Journal: Blood
Blood (2022) 140 (Supplement 1): 7527–7528.
https://doi.org/10.1182/blood-2022-169212
Published: 2022
Journal Articles

Complement and the prothrombotic state

Free
Christoph Q. Schmidt, Hubert Schrezenmeier, David Kavanagh
Journal: Blood
Blood (2022) 139 (13): 1954–1972.
https://doi.org/10.1182/blood.2020007206
Published: 2022
Journal Articles

Constitutional PIGA mutations cause a novel subtype of hemochromatosis in patients with neurologic dysfunction

Open Access
Lena Muckenthaler, Oriana Marques, Silvia Colucci, Joachim Kunz, Piotr Fabrowski, Thomas Bast, Sandro Altamura, Britta Höchsmann, Hubert Schrezenmeier, Monika Langlotz, Paulina Richter-Pechanska, Tobias Rausch, Nicole Hofmeister-Mielke, Nikolas Gunkel, Matthias W. Hentze, Andreas E. Kulozik, Martina U. Muckenthaler
Journal: Blood
Blood (2022) 139 (9): 1418–1422.
https://doi.org/10.1182/blood.2021013519
Published: 2022
Includes: Supplemental data