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David Kavanagh
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Journal Articles

Atypical hemolytic uremic syndrome in the era of terminal complement inhibition: an observational cohort study

CME Clinical Trials & Observations
Vicky Brocklebank, Patrick R. Walsh, Kate Smith-Jackson, Thomas M. Hallam, Kevin J. Marchbank, Valerie Wilson, Theophile Bigirumurame, Tina Dutt, Emma K. Montgomery, Michal Malina, Edwin K. S. Wong, Sally Johnson, Neil S. Sheerin, David Kavanagh
Journal: Blood
Blood (2023) 142 (16): 1371–1386.
https://doi.org/10.1182/blood.2022018833
Published: 2023
Includes: Supplemental data
Journal Articles

Complement and the prothrombotic state

Christoph Q. Schmidt, Hubert Schrezenmeier, David Kavanagh
Journal: Blood
Blood (2022) 139 (13): 1954–1972.
https://doi.org/10.1182/blood.2020007206
Published: 2022
Journal Articles

Two-Year Efficacy and Safety of Ravulizumab in Adults and Children with Atypical Hemolytic Uremic Syndrome (aHUS): Analysis of Two Phase 3 Studies

Bradley P. Dixon, Alvaro Domingo Madris-Aris, Brigitte Adams, David Kavanagh, Hee Gyung Kang, Jimmy Wang, Katherine Garlo, Kazuki Tanaka, Laurence Greenbaum, Masayo Ogawa, Nils Heyne, Seong Heon Kim, Spero Cataland, Sung-Soo Yoon, Yoshitaka Miyakawa, Yosu Luque, Melissa Muff-Luett
Journal: Blood
Blood (2021) 138 (Supplement 1): 769.
https://doi.org/10.1182/blood-2021-145040
Published: 2021
Journal Articles

Management of thrombotic microangiopathy in pregnancy and postpartum: report from an international working group

Fadi Fakhouri, Marie Scully, François Provôt, Miquel Blasco, Paul Coppo, Marina Noris, Kathy Paizis, David Kavanagh, Frédéric Pène, Sol Quezada, Alexandre Hertig, Sébastien Kissling, Patrick O’Brien, Yahsou Delmas, Lorenzo Alberio, Norbert Winer, Agnès Veyradier, Spero Cataland, Véronique Frémeaux-Bacchi, Chantal Loirat, Giuseppe Remuzzi, Vassilis Tsatsaris
Journal: Blood
Blood (2020) 136 (19): 2103–2117.
https://doi.org/10.1182/blood.2020005221
Published: 2020
Includes: Supplemental data
Journal Articles

Type I interferon causes thrombotic microangiopathy by a dose-dependent toxic effect on the microvasculature

David Kavanagh, Sarah McGlasson, Alexa Jury, Jac Williams, Neil Scolding, Chris Bellamy, Claudia Gunther, Diane Ritchie, Daniel P. Gale, Yashpal S. Kanwar, Rachel Challis, Holly Buist, James Overell, Belinda Weller, Oliver Flossmann, Mark Blunden, Eric P. Meyer, Thomas Krucker, Stephen J. W. Evans, Iain L. Campbell, Andrew P. Jackson, Siddharthan Chandran, David P. J. Hunt
Journal: Blood
Blood (2016) 128 (24): 2824–2833.
https://doi.org/10.1182/blood-2016-05-715987
Published: 2016
Includes: Supplemental data
Journal Articles

Identification Of aHUS and Complement Mutations In Patients Presenting With Acute Thrombotic Microangiopathy

Elizabeth H Phillips, MD, John Connolly, MD, John-Paul Westwood, MD, Siobhan McGuckin, Daniel P Gale, MD, Tim H. J. Goodship, MD, David Kavanagh, MD, Marie A Scully, MD
Journal: Blood
Blood (2013) 122 (21): 1073.
https://doi.org/10.1182/blood.V122.21.1073.1073
Published: 2013
Journal Articles

A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome

Nigel J. Francis, Bairbre McNicholas, Atif Awan, Mary Waldron, Donal Reddan, Denise Sadlier, David Kavanagh, Lisa Strain, Kevin J. Marchbank, Claire L. Harris, Timothy H. J. Goodship
Journal: Blood
Blood (2012) 119 (2): 591–601.
https://doi.org/10.1182/blood-2011-03-339903
Published: 2012
Includes: Supplemental data
Journal Articles

Association of factor H autoantibodies with deletions of CFHR1 , CFHR3 , CFHR4 , and with mutations in CFH , CFI , CD46 , and C3 in patients with atypical hemolytic uremic syndrome

Iain Moore, Lisa Strain, Isabel Pappworth, David Kavanagh, Paul N. Barlow, Andrew P. Herbert, Christoph Q. Schmidt, Scott J. Staniforth, Lucy V. Holmes, Roy Ward, Lynn Morgan, Timothy H. J. Goodship, Kevin J. Marchbank
Journal: Blood
Blood (2010) 115 (2): 379–387.
https://doi.org/10.1182/blood-2009-05-221549
Published: 2010
Journal Articles

Genetics of HUS: the impact of MCP, CFH , and IF mutations on clinical presentation, response to treatment, and outcome

Clinical Trials & Observations
Jessica Caprioli, Marina Noris, Simona Brioschi, Gaia Pianetti, Federica Castelletti, Paola Bettinaglio, Caterina Mele, Elena Bresin, Linda Cassis, Sara Gamba, Francesca Porrati, Sara Bucchioni, Giuseppe Monteferrante, Celia J. Fang, M. K. Liszewski, David Kavanagh, John P. Atkinson, Giuseppe Remuzzi, for the International Registry of Recurrent and Familial HUS/TTP
Journal: Blood
Blood (2006) 108 (4): 1267–1279.
https://doi.org/10.1182/blood-2005-10-007252
Published: 2006