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W. Jason Cummings
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Journal Articles

Monotherapy Treatment with Zaltenibart (OMS906), an Alternative Pathway Masp-3 Inhibitor, Improved Key Hematologic Parameters in Patients with PNH with a Suboptimal Response to Ravulizumab: Interim Results from a Phase 2 Proof-of-Concept Study

Morag Griffin, Richard J. Kelly, Mathilde Gavillet, Petra Muus, Britta Hoechsmann, W. Jason Cummings, John Efthimiou, William Pullman, Hubert Schrezenmeier, Jens Panse
Journal: Blood
Blood (2024) 144 (Supplement 1): 4072.
https://doi.org/10.1182/blood-2024-205866
Published: 2024
Journal Articles

Population Pharmacokinetics/Pharmacodynamics and Clinical Pharmacology of Zaltenibart (OMS906) in Healthy Subjects and Patients with PNH

W. Jason Cummings, Yi Li, Siobhan Hayes, Richard Mills, Colm Farrell, Morag Griffin, J. Steve Whitaker, William Pullman
Journal: Blood
Blood (2024) 144 (Supplement 1): 4081.
https://doi.org/10.1182/blood-2024-206009
Published: 2024
Journal Articles

Alternative Pathway Masp-3 Inhibitor OMS906 Effectively and Potently Inhibits Complement-Mediated Hemolysis in Preclinical Models Mechanistically Similar to Paroxysmal Nocturnal Hemoglobinuria

Yi Li, Munehisa Yabuki, W. Jason Cummings
Journal: Blood
Blood (2023) 142 (Supplement 1): 4082.
https://doi.org/10.1182/blood-2023-177730
Published: 2023
Journal Articles

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Alternative Pathway Masp-3 Inhibitor OMS906 in a Phase 1 Study of Healthy Subjects

William Pullman, Jane Humphreys, Edward Philpot, W. Jason Cummings
Journal: Blood
Blood (2022) 140 (Supplement 1): 5801–5802.
https://doi.org/10.1182/blood-2022-162828
Published: 2022