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Journal Articles

Mapping Genotype to Phenotype in Clonal Hematopoiesis Uncovers Downregulated MHC-II Molecules in DNMT3A R882 - Mutant Hematopoietic Stem Cells

Patrick Stelmach, Dominik Vonficht, Anne Kathrin Merbach, Dawn S Lin, Sergi Beneyto-Calabuig, Marina Scheller, Aino-Maija Leppä, Florian Grünschläger, George S Vassiliou, Simon Haas, Lars Velten, Carsten Müller-Tidow, Andreas Trumpp
Journal: Blood
Blood (2024) 144 (Supplement 1): 1292.
https://doi.org/10.1182/blood-2024-203041
Published: 2024
Journal Articles

Data-Informed, Refined Immunophenotypic Classification of Adult T-Lineage Acute Lymphoblastic Leukemia

Stefan Habringer, Iva Todorova, Frederik Herzberg, Daniel Steiert, Arik Horne, Thomas Burmeister, Simon Haas, Ulrich Keller, Monika Brüggemann, Michaela Kotrova, Claudia D Baldus, Nicola Goekbuget, Martin Neumann, Stefan Schwartz
Journal: Blood
Blood (2024) 144 (Supplement 1): 1460.
https://doi.org/10.1182/blood-2024-202301
Published: 2024
Journal Articles

Unraveling and Visualizing the Interactions of Acute Myeloid Leukemia with the Bone Marrow Microenvironment in Vitro and In Vivo

Karin Prummel, Anna Mathioudaki, Lixiazi He, Shubhankar Sood, Rim Moussa, Robert Reinhardt, Swati Garg, Simon Haas, Marieke Essers, Sinem K Saka, Caroline Pabst, Judith Zaugg
Journal: Blood
Blood (2022) 140 (Supplement 1): 5770–5771.
https://doi.org/10.1182/blood-2022-170377
Published: 2022
Journal Articles

Bone Marrow Immune Signatures in Multiple Myeloma Are Linked to Tumor Heterogeneity and Treatment Outcome

Simon Steiger, Raphael Lutz, Nina Prokoph, Subarna Palit, Stephan M Tirier, Philipp Reichert, Anja Baumann, Nadine Hefner, Sabrina Schumacher, Dominik Vonficht, Florian Grünschläger, Alexandra M Poos, Lukas John, Laleh Haghverdi, Jan-Philipp Mallm, Elias K Mai, Mirco Friedrich, Katharina Kriegsmann, Mohamed H.S. Awwad, Anna Jauch, Uta Bertsch, Diana Tichy, Carsten Müller-Tidow, Roland Schroers, Hans Salwender, Britta Besemer, Roland Fenk, Katja Weisel, Hartmut Goldschmidt, Stefanie Huhn, Michael Hundemer, Karsten Rippe, Simon Haas, Niels Weinhold, Marc S Raab
Journal: Blood
Blood (2022) 140 (Supplement 1): 2083–2085.
https://doi.org/10.1182/blood-2022-168685
Published: 2022
Journal Articles

Multi-Omics Profiling of JMML HSPCs Reveals Onco-Fetal Reprogramming and Identifies Novel Prognostic Biomarkers and Therapeutic Targets in High-Risk JMML

Mark Hartmann, Ling Hai, Joschka Hey, Maximilian Schönung, Valentin Maurer, Jovana Rajak, Sina Staeble, Jens Langstein, Katharina Bauer, Mariam Hakobyan, Laura Jardine, Sheila Bohler, Dominik Vonficht, Abdul-Habib Maag, Dirk Lebrecht, Kathrin M. Bernt, Roland Roelz, Tobias Boch, Eleonora Khabirova, Pavlo Lutsik, Oliver Stegle, Simon Haas, Muzlifah Haniffa, Sam Behjati, Jan-Philipp Mallm, Christian Buske, Stefan Fröhling, Christoph Plass, Charlotte M. Niemeyer, Christian Flotho, Marc Jan Bonder, Miriam Erlacher, Matthias Schlesner, Daniel B. Lipka
Journal: Blood
Blood (2022) 140 (Supplement 1): 8729–8730.
https://doi.org/10.1182/blood-2022-162224
Published: 2022
Journal Articles

The Bone Marrow Microenvironment of Multiple Myeloma Long-Term Survivors at Single Cell Resolution

Raphael Lutz, MD, Abdelrahman Mahmoud, Mohamed H.S. Awwad, Charles D. Imbusch, PhD, Tobias Boch, MD, Brian G.M. Durie, MD, Niels Weinhold, PhD, Marc S. Raab, MD, Carsten Müller-Tidow, MD, Simon Haas, PhD, Benedikt Brors, PhD, Hartmut Goldschmidt, MD, Michael Hundemer, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32–33.
https://doi.org/10.1182/blood-2020-142298
Published: 2020
Journal Articles

No Evidence for Hematopoietic Stem Cell Self-Renewal in-Vivo Following Inflammatory Challenge

Ruzhica Bogeska, PhD, Paul Kaschutnig, PhD, Stella V Paffenholz, MSc, Julia Knoch, Jan-Philipp Mallm, PhD, Malak Fawaz, MSc, Florian Buettner, PhD, Dagmar Walter, PhD, Felix Frauhammer, MSc, Tim Holland-Letz, PhD, Noboru Asada, MD PhD, Ana-Matea Mikecin Drazic, PhD, Marleen Buechler-Schaff, MSc, Martha Correno-Gonzalez, Melanie Ball, Sina Staeble, MSc, Julius Gräsel, PhD, Simon Haas, PhD, Daniel B. Lipka, MD, Karsten Rippe, PhD, Benedikt Brors, PhD, Paul S. Frenette, MD, Michael A. Rieger, Marieke A. G. Essers, PhD, Michael D. Milsom, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 456.
https://doi.org/10.1182/blood-2019-125744
Published: 2019
Journal Articles

Deconvolution of Hematopoietic Commitment Decisions By Genome-Wide Analysis of Progressive DNA Methylation Changes

Sina Staeble, MSc, Stephen Kraemer, MSc, Jens Langstein, MSc, Ruzhica Bogeska, PhD, Mark Hartmann, PhD, Maximilian Schoenung, MSc, Melinda Czeh, PhD, Julia Knoch, Natasha Anstee, PhD, Simon Haas, PhD, Abdelrahman Mahmoud, MSc, Julius Graesel, MSc, Daniel Huebschmann, MD PhD, Lars Feuerbach, PhD, Weichenhan Dieter, PhD, Benedikt Brors, PhD, Karsten Rippe, PhD, Jan-Philipp Mallm, PhD, Frank Rosenbauer, PhD, Christoph Plass, PhD, Matthias Schlesner, PhD, Michael D. Milsom, PhD, Daniel B. Lipka, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1179.
https://doi.org/10.1182/blood-2019-124429
Published: 2019
Journal Articles

Combined Single-Cell and Spatial Transcriptomics to Deconvolute the Hematopoietic Stem Cell Niche

Simon Haas, PhD, Chiara Baccin, Jude Al-Sabah, Lars Velten, PhD, Steinmetz Lars, PhD, Andreas Trumpp, Prof, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 876.
https://doi.org/10.1182/blood-2018-99-118479
Published: 2018
Journal Articles

A Stem Cell-Based Epigenetic Memory Mediates Interferon Response-Heterogeneity within the Hematopoietic System

Simon Haas, PhD, Christoph Hirche, PhD, Alexandra Schnell, Can Sönmezer, Jens Langstein, Stephan Wurzer, PhD, Marc Thier, PhD, Sandra Blaszkiewicz, Franziska Pilz, Michael D. Milsom, PhD, Andreas Trumpp, Prof, PhD, Daniel Lipka, MD, Ulrich Kalinke, Prof, PhD, Marieke A. G. Essers, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 634.
https://doi.org/10.1182/blood.V130.Suppl_1.634.634
Published: 2017
Journal Articles

Hematopoietic Stem Cells Fail to Regenerate In Vivo Following Inflammatory Stress

Ruzhica Bogeska, PhD, Paul Kaschutnig, Stella Paffenholz, Julia Maassen, Jan-Philipp Mallm, Felix Wertek, Dagmar Walter, PhD, Blaszkiewicz Sandra, Tim Holland-Letz, Noboru Asada, MD PhD, Julius Gräsel, Sina Stäble, Milena Block, Özge Gizlenci, Áine M. Prendergast, PhD, Simon Haas, Daniel B Lipka, Karsten Rippe, Benedikt Brors, Paul S. Frenette, MD, Marieke A. G. Essers, Michael D. Milsom, PhD
Journal: Blood
Blood (2016) 128 (22): 1472.
https://doi.org/10.1182/blood.V128.22.1472.1472
Published: 2016
Journal Articles

Epigenetic Drug Treatment Globally Induces Cryptic Transcription Start Sites Encoded in Long Terminal Repeats

Michael Daskalakis, David Brocks, Christopher Schmidt, Daofeng Li, Jing Li, Hyo S. Jang, Bo Zhang, Daniel B Lipka, Johanna Schott, Holger Bierhoff, Yassen Assenov, Monika Helf, Alzbeta Ressnerova, Anders Lindroth, Simon Haas, Marieke A. G. Essers, Charles D. Imbusch, Benedikt Brors, Ina Oehme, Olaf Witt, Michael Lübbert, MD, Georg Stoecklin, Clarissa Gerhäuser, Christopher C Oakes, PhD, Ting Wang, Christoph Plass
Journal: Blood
Blood (2016) 128 (22): 3931.
https://doi.org/10.1182/blood.V128.22.3931.3931
Published: 2016
Journal Articles

Ifnα Mediated Remodeling of the Bone Marrow Stem Cell Vascular Niche

Áine M. Prendergast, PhD, Andrea Kuck, Mieke van Essen, Simon Haas, Sandra Blaszkiewicz, Marieke A. G. Essers
Journal: Blood
Blood (2016) 128 (22): 2667.
https://doi.org/10.1182/blood.V128.22.2667.2667
Published: 2016
Journal Articles

Stem Cell-like Megakaryocyte Progenitors As Driving Forces of IFN-Induced Emergency Megakaryopooesis

Simon Haas, Jenny Hansson, Daniel Klimmeck, Dirk Loeffler, Lars Velten, Hannah Uckelmann, Stephan Wurzer, Áine M. Prendergast, PhD, Alexandra Schnell, Klaus Hexel, Rachel Santarella-Mellwig, Sandra Blaszkiewicz, Andrea Kuck, Hartmut Geiger, PhD, Michael D. Milsom, PhD, Lars M Steinmetz, Timm Schroeder, PhD, Andreas Trumpp, PhD, Jeroen Krijgsveld, Marieke A. G. Essers, PhD
Journal: Blood
Blood (2015) 126 (23): 2391.
https://doi.org/10.1182/blood.V126.23.2391.2391
Published: 2015