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Yassen Assenov
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Journal Articles

Recurrent Mutations in EGR2 Direct Specific Epigenetic Reconfiguration in Chronic Lymphocytic Leukemia

Christoph Weigel, PhD, Yassen Assenov, Charles Imbusch, Qi Wang, Renée Beekman, Brian Giacopelli, BS, Yue-zhong Wu, MSc, David Brocks, Weichenhan Dieter, Popanda Odilia, Peter Schmezer, Benedikt Brors, Daniel Mertens, Karsten Rippe, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD PhD, Jennifer A. Woyach, MD, James S. Blachly, MD, Elias Campo, Thorsten Zenz, MD, John C. Byrd, MD, José I. Martin-Subero, PhD, Christoph Plass, Christopher C. Oakes
Journal: Blood
Blood (2018) 132 (Supplement 1): 650.
https://doi.org/10.1182/blood-2018-99-119070
Published: 2018
Journal Articles

Modeling of the Epigenome of the Cell-of-Origin Identifies Cancer-Specific DNA Methylation Patterns in CLL

Justyna Anna Wierzbinska, Reka Toth, Naveed Ishaque, Jan-Phillip Mallm, Karsten Rippe, Daniel Mertens, Thomas Hielscher, Thorsten Zenz, MD, Marc Seifert, Ralf Küppers, Yassen Assenov, Stephan Stilgenbauer, John C. Byrd, MD, Christopher C. Oakes, Daniel B. Lipka, Christoph Plass
Journal: Blood
Blood (2018) 132 (Supplement 1): 3885.
https://doi.org/10.1182/blood-2018-99-115941
Published: 2018
Journal Articles

PDX Models Recapitulate Genetics and Epigenetics of Pediatric T-Cell Leukemia

Caroline Von Knebel Doeberitz, Paulina Richter-Pechanska, PhD, Viktoras Frismantas, MSc, Joachim B. Kunz, MD, Tobias Rausch, Beat Bornhauser, PhD, Martin Zimmermann, PhD, Obul Reddy Bandapalli, PhD, Elena Orlova, Julia Seeman, Busra Erarslan, Yassen Assenov, Martin Stanulla, MD PhD, Martin Schrappe, MD PhD, Gunnar Cario, MD, Gabriele Escherich, MD, Kseniya Bakharevich, Renate Kirschner-Schwabe, PhD, Cornelia Eckert, PhD, Jan O. Korbel, PhD, Martina Muckenthaler, Jean-Pierre Bourquin, MD PhD, Andreas E. Kulozik, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2723.
https://doi.org/10.1182/blood.V130.Suppl_1.2723.2723
Published: 2017
Journal Articles

Epigenetic Drug Treatment Globally Induces Cryptic Transcription Start Sites Encoded in Long Terminal Repeats

Michael Daskalakis, David Brocks, Christopher Schmidt, Daofeng Li, Jing Li, Hyo S. Jang, Bo Zhang, Daniel B Lipka, Johanna Schott, Holger Bierhoff, Yassen Assenov, Monika Helf, Alzbeta Ressnerova, Anders Lindroth, Simon Haas, Marieke A. G. Essers, Charles D. Imbusch, Benedikt Brors, Ina Oehme, Olaf Witt, Michael Lübbert, MD, Georg Stoecklin, Clarissa Gerhäuser, Christopher C Oakes, PhD, Ting Wang, Christoph Plass
Journal: Blood
Blood (2016) 128 (22): 3931.
https://doi.org/10.1182/blood.V128.22.3931.3931
Published: 2016
Journal Articles

Progressive Epigenetic Programming during B Cell Maturation Is Reflected in a Continuum of Epigenetic Disease Phenotypes in Chronic Lymphocytic Leukemia

Christopher C. Oakes, PhD, Marc Seifert, Yassen Assenov, Lei Gu, Martina Przekopowitz, Amy S. Ruppert, MAS, Qi Wang, Charles Imbusch, Andrius Serva, Sandra Koser, David Brocks, Daniel B Lipka, Olga Bogatyrova, Benedikt Brors, Dieter Weichenhan, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD PhD, Daniel Mertens, PhD, Marc Zapatka, Peter Lichter, Hartmut Döhner, MD, Ralf Kueppers, Thorsten Zenz, Stephan Stilgenbauer, MD, John C Byrd, MD, Christoph Plass, PhD
Journal: Blood
Blood (2015) 126 (23): 2436.
https://doi.org/10.1182/blood.V126.23.2436.2436
Published: 2015
Journal Articles

Targeted Deep Sequencing of Genetic Alterations Identified By Whole Exome Sequencing Reveals Clonal Evolution in Pediatric T-Lymphoblastic Leukemia

Joachim Kunz, MD, Obul R Bandapalli, PhD, Tobias Rausch, PhD, Adrian Stuetz, PhD, Paulina Pechanska, PhD, Yassen Assenov, Juliane Eilers, Elena Orlova, Judit Sagi, Martin Stanulla, MD, Martin Schrappe, Rupert Handgretinger, Renate Kirschner-Schwabe, PhD, Jana Hof, MSc, Cornelia Eckert, PhD, Smadar Avigad, PhD, Rolf Koehler, PhD, Martina U. Muckenthaler, Jan Korbel, PhD, Andreas E Kulozik
Journal: Blood
Blood (2014) 124 (21): 491.
https://doi.org/10.1182/blood.V124.21.491.491
Published: 2014
Journal Articles

Heterogeneity and Evolution Of DNA Methylation In Chronic Lymphocytic Leukemia

Christopher C Oakes, Ph.D, Rainer Claus, MD, Lei Gu, Yassen Assenov, Jennifer Hüllein, Manuela Zucknick, David Brocks, Olga Bogatyrova, Christopher R. Schmidt, Laura Rassenti, PhD, Thomas J. Kipps, MD, PhD, Daniel Mertens, PhD, Peter Lichter, PhD, Hartmut Döhner, MD, Stephan Stilgenbauer, MD, John C. Byrd, MD, Thorsten Zenz, MD, Christoph Plass, PhD
Journal: Blood
Blood (2013) 122 (21): 1626.
https://doi.org/10.1182/blood.V122.21.1626.1626
Published: 2013