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Thomas Hielscher
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Journal Articles

Salvage Autologous Transplant and Lenalidomide Maintenance Versus Continuous Lenalidomide/Dexamethasone for Relapsed Multiple Myeloma: Long Term Follow up Results of the Randomized GMMG Phase III Multicenter Trial Relapse

Marc-Andrea Baertsch, Jana Schlenzka, Thomas Hielscher, Marc S. Raab, Sandra Sauer, Maximilian Merz, Elias K. Mai, Carsten Müller-Tidow, Steffen Luntz, Anna Jauch, Peter Brossart, Martin Goerner, Stefan Klein, Bertram Glass, Peter Reimer, Ullrich Graeven, Roland Fenk, Mathias Hänel, Ivana von Metzler, Lindemann Hans W., Christof Scheid, Axel Nogai, Hans Salwender, Richard Noppeney, Britta Besemer, Katja Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2023) 142 (Supplement 1): 782.
https://doi.org/10.1182/blood-2023-178835
Published: 2023
Journal Articles

Prediction of Early Death and Severe Infections during Novel Agent-Based Induction Therapy in Newly-Diagnosed Multiple Myeloma: An Intergroup Analysis from the German Speaking Myeloma Multicenter Group, the Dutch-Belgian Cooperative Trial Group for Hematology Oncology Foundation and the European Myeloma Network

Elias K Mai, Thomas Hielscher, Uta Bertsch, Hans Salwender, Sonja Zweegman, Markus Munder, Lucia Pantani, Peter Brossart, Meral Beksac, Igor Wolfgang Blau, Marc-Steffen Raab, Jan Dürig, Nicola Giesen, Britta Besemer, Roland Fenk, Peter Reimer, Bronno van der Holt, Mathias Haenel, Ivana v. Metzler, Ullrich Graeven, Mario Boccadoro, Christof Scheid, Meletios A. Dimopoulos, Katja Weisel, Michele Cavo, Pieter Sonneveld, Hartmut Goldschmidt
Journal: Blood
Blood (2021) 138 (Supplement 1): 3792.
https://doi.org/10.1182/blood-2021-145289
Published: 2021
Journal Articles

Bortezomib-Based Induction and Maintenance Overcomes the Negative Prognostic Impact of Renal Impairment and del17p in Transplant-Eligible Myeloma Patients: Long Term Results from the Phase III HOVON-65/GMMG-HD4 Study after Median 137 Months Follow up

Christof Scheid, MD, Henk Lokhorst, MD PhD, Igor W Blau, MD PhD, Bronno Van Der Holt, PhD, Uta Bertsch, Sonja Zweegman, MD PhD, Katja Weisel, Edo Vellenga, Marie José Kersten, MD PhD, Sandra Croockewit, Elias K Mai, MD, Reinier Raymakers, MD PhD, Dirk Hose, MD, Anna Jauch, Jens Hillengass, MD, Marian Stevens-Kroef, PhD, Marc S Raab, MD PhD, Kai Neben, Stephan Stilgenbauer, Annemiek Broyl, MD PhD, Hans-Walter Lindemann, MD, Gerard Bos, MD PhD, Peter Brossart, MD, Marinus van Marwijk Kooij, MD PhD, Paula F Ypma, MD PhD, Ulrich Dührsen, Prof, MD PhD, Ron Schaafsma, MD PhD, Thomas Hielscher, Hans Salwender, Hartmut Goldschmidt, MD, Pieter Sonneveld
Journal: Blood
Blood (2019) 134 (Supplement_1): 3308.
https://doi.org/10.1182/blood-2019-129684
Published: 2019
Journal Articles

Treatment Response and Long-Term Survival in Multiple Myeloma in the GMMG-HD4 Trial - Neither Profit All Molecular Entities Alike, Nor Are Remissions to Different Regimen Equal

Anja Seckinger, Hans Jürgen Salwender, MD, Hans Martin, MD, Christof Scheid, Thomas Hielscher, Uta Bertsch, MD, Manuela Hummel, Anna Jauch, PhD, Wolfgang Knauf, Martina Emde, Susanne Beck, Kai Neben, Henk M. Lokhorst, MD PhD, Bronno van der Holt, PhD, Ulrich Duehrsen, MD, Jan Dürig, Hans-Walter Lindemann, MD, Ingo Schmidt-Wolf, Mathias Haenel, MD, Bernd Lathan, Marc S Raab, MD PhD, Carsten Müller-Tidow, MD, Pieter Sonneveld, MD PhD, Igor Wolfgang Blau, Jens Hillengass, MD, Katja Weisel, MD, Hartmut Goldschmidt, MD, Dirk Hose, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4485.
https://doi.org/10.1182/blood-2018-99-113284
Published: 2018
Journal Articles

Modeling of the Epigenome of the Cell-of-Origin Identifies Cancer-Specific DNA Methylation Patterns in CLL

Justyna Anna Wierzbinska, Reka Toth, Naveed Ishaque, Jan-Phillip Mallm, Karsten Rippe, Daniel Mertens, Thomas Hielscher, Thorsten Zenz, MD, Marc Seifert, Ralf Küppers, Yassen Assenov, Stephan Stilgenbauer, John C. Byrd, MD, Christopher C. Oakes, Daniel B. Lipka, Christoph Plass
Journal: Blood
Blood (2018) 132 (Supplement 1): 3885.
https://doi.org/10.1182/blood-2018-99-115941
Published: 2018
Journal Articles

Quantitative Integrative Prediction of Survival Probability in Multiple Myeloma Using Molecular and Clinical Prognostic Factors in 657 Patients Treated with Bortezomib-Based Induction, High-Dose Therapy and Autologous Stem Cell Transplantation

Manuela Hummel, Thomas Hielscher, Hans Jürgen Salwender, MD, Christof Scheid, Hans Martin, MD, Uta Bertsch, MD, Hartmut Goldschmidt, MD, Anja Seckinger, Dirk Hose, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 403.
https://doi.org/10.1182/blood-2018-99-113307
Published: 2018
Journal Articles

Salvage Autologous Transplant and Lenalidomide Maintenance Versus Continuous Lenalidomide/Dexamethasone for Relapsed Multiple Myeloma: Results of the Randomized GMMG Phase III Multicenter Trial Relapse

Hartmut Goldschmidt, MD, Marc-A. Baertsch, MD, Jana Schlenzka, MD, Natalia Becker, PhD, Habermehl Christina, PhD, Thomas Hielscher, Marc S Raab, MD, Jens Hillengass, MD, Carsten Müller-Tidow, MD, Steffen Luntz, MD, Anna Jauch, PhD, Peter Brossart, MD, Martin Goerner, MD, Stefan A Klein, MD, Martin Schmidt-Hieber, MD PhD, Peter Reimer, MD, Ullrich Graeven, MD, Roland Fenk, MD PhD, Mathias Haenel, MD, Hans Martin, MD, Hans-Walter Lindemann, MD, Christoph Scheid, MD, Axel Nogai, MD, Hans Jürgen Salwender, MD, Richard Noppeney, MD, Katja Weisel, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 253.
https://doi.org/10.1182/blood-2018-99-111203
Published: 2018
Journal Articles

Subgroup Analyses of the Randomized GMMG Phase III Multicenter Trial Relapse Suggest Survival Benefit of Salvage Autologous Transplant Primarily in Low Risk Multiple Myeloma

Marc-A. Baertsch, MD, Jana Schlenzka, MD, Habermehl Christina, PhD, Thomas Hielscher, Marc S Raab, MD, Jens Hillengass, MD, Carsten Müller-Tidow, MD, Steffen Luntz, MD, Anna Jauch, PhD, Peter Brossart, MD, Martin Goerner, MD, Stefan A Klein, MD, Martin Schmidt-Hieber, MD PhD, Peter Reimer, MD, Ullrich Graeven, MD, Roland Fenk, MD PhD, Mathias Haenel, MD, Hans Martin, MD, Hans-Walter Lindemann, MD, Christoph Scheid, MD, Axel Nogai, MD, Hans Jürgen Salwender, MD, Richard Noppeney, MD, Katja Weisel, MD, Hartmut Goldschmidt, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 254.
https://doi.org/10.1182/blood-2018-99-119762
Published: 2018
Journal Articles

Cohesin Subunit SMC3 Levels Impact on Karyotype and Outcome in Acute Myeloid Leukemia

Bianca Kraft, PhD, Jan Lombard, Michael Kirsch, Patrick Wuchter, MD, Peter Bugert, MD, Thomas Hielscher, Norbert Blank, MD, Alwin Kraemer, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2786.
https://doi.org/10.1182/blood-2018-99-118454
Published: 2018
Journal Articles

Profiling of Oncogenic Signaling in Multiple Myeloma — Association with Biology, Disease Progression and Prognosis

Nicola Lehners, Jing Xu, Thomas Hielscher, Leo Rasche, Elena Ellert, Albrecht Stenzinger, Peter Schirmacher, Carsten Müller-Tidow, MD, Hartmut Goldschmidt, MD, Mindaugas Andrulis, Niels Weinhold, PhD, Marc S Raab, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3206.
https://doi.org/10.1182/blood-2018-99-116214
Published: 2018
Journal Articles

Prognostic Impact of Tandem Autologous Stem Cell Transplantation (ASCT) in Different Response Subgroups after 1 st ASCT

Joanna Blocka, MD, Thomas Hielscher, PhD, Hartmut Goldschmidt, MD, Maria Pritsch, Dr. rer. nat., Jens Hillengass, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3295.
https://doi.org/10.1182/blood.V130.Suppl_1.3295.3295
Published: 2017
Journal Articles

A Predictive Score for Early Mortality during Induction Therapy in Newly Diagnosed Transplant-Eligible Multiple Myeloma - an Analysis from Five GMMG and HOVON Multicenter Phase III Trials

Elias K Mai, MD, Thomas Hielscher, PhD, Uta Bertsch, MD, Jana Schlenzka, MD, Hans Jürgen Salwender, Henk M Lokhorst, Markus Munder, MD, Bronno van der Holt, Christian Gerecke, MD, Michael Pfreundschuh, MD, Ulrich Duhrsen, Peter Brossart, MD, Sonja Zweegman, MD PhD, Kai Neben, Jens Hillengass, MD, Marc-Steffen S Raab, Dirk Hose, MD, Edo Vellenga, MD, Maximilian Merz, MD, Iris Breitkreutz, MD, Anna Jauch, Marie José Kersten, MD, Hans Martin, Hans-Walter Lindemann, Norma Peter, MD, Sandra Croockewit, MD, Igor Wolfgang Blau, MD, Christof Scheid, MD, Katja C. Weisel, Pieter Sonneveld, MDPhD, Hartmut Goldschmidt, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2016.
https://doi.org/10.1182/blood.V130.Suppl_1.2016.2016
Published: 2017
Journal Articles

Response-Adapted Lenalidomide Maintenance in Newly Diagnosed, Transplant-Eligible Multiple Myeloma: Results from the Multicenter Phase III GMMG-MM5 Trial

Hartmut Goldschmidt, MD, Elias K Mai, MD, Jan Dürig, MD, Christof Scheid, MD, Katja C. Weisel, Christina Kunz, Uta Bertsch, MD, Thomas Hielscher, PhD, Markus Munder, MD, Hans-Walter Lindemann, Barbara Huegle-Doerr, Dirk Hose, MD, Anja Seckinger, Stefanie Huhn, PhD, Anna Jauch, Bernhard Rabold, Ahmet Elmaagacli, MD, Christian Gerecke, MD, Peter Brossart, MD, Martin Goerner, MD, Helga Bernhard, MD, Martin Hoffmann, MD, Jens Hillengass, MD, Marc-Steffen S Raab, Igor Wolfgang Blau, MD, Mathias Hänel, MD, Hans Jürgen Salwender
Journal: Blood
Blood (2017) 130 (Supplement 1): 400.
https://doi.org/10.1182/blood.V130.Suppl_1.400.400
Published: 2017
Journal Articles

Circulating Tumor Cells As a Surrogate Marker for Bone Marrow Minimal Residual Disease and an Adverse Prognostic Factor for Patients with Multiple Myelom

Stefanie Huhn, PhD, Mathias Hänel, MD, Thomas Hielscher, PhD, Uta Bertsch, MD, Hans Jürgen Salwender, Norma Peter, MD, Hartmut Kirchner, Helga Bernhard, MD, Martin Vogel, Ralf Angermund, Martin Goerner, MD, Katja C. Weisel, Jan Duering, Igor W Blau, Niels Weinhold, PhD, Hartmut Goldschmidt, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4359.
https://doi.org/10.1182/blood.V130.Suppl_1.4359.4359
Published: 2017
Journal Articles

Systemic Versus Local Treatment in Patients with Multiple Myeloma and a Single Lesion in Whole Body Imaging

Sandra Sauer, MD, Anna Bergmann, Barbara Wagner, Thomas Hielscher, PhD, Carsten Müller-Tidow, Hartmut Goldschmidt, MD, Jens Hillengass, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3092.
https://doi.org/10.1182/blood.V130.Suppl_1.3092.3092
Published: 2017
Journal Articles

Direct Assessment of IgA and IgG Paraprotein By Hevylite Assay and Correlation to IMWG Response and Progression-Free Survival in Newly Diagnosed, Transplant-Eligible Multiple Myeloma Patients in the Prospective Phase III GMMG-MM5 Trial

Christof Scheid, MD, Anja Seckinger, Jan Dürig, MD, Katja C. Weisel, Christina Kunz, Uta Bertsch, MD, Thomas Hielscher, PhD, Markus Munder, MD, Hans-Walter Lindemann, Barbara Huegle-Doerr, Stefanie Huhn, PhD, Elias K Mai, MD, Anna Jauch, Bernhard Rabold, Christian Gerecke, MD, Peter Brossart, MD, Martin Goerner, MD, Helga Bernhard, MD, Martin Hoffmann, MD, Jens Hillengass, MD, Marc-Steffen S Raab, Igor Wolfgang Blau, MD, Mathias Haenel, Dirk Hose, MD, Hartmut Goldschmidt, MD, Hans Jürgen Salwender
Journal: Blood
Blood (2017) 130 (Supplement 1): 1784.
https://doi.org/10.1182/blood.V130.Suppl_1.1784.1784
Published: 2017
Journal Articles

Asymptomatic Multiple Myeloma - Background of Progression, Evolution, and Prognosis

Anja Seckinger, MD, Anna Jauch, PhD, Martina Emde, Susanne Beck, Marcel Mohr, Martin Granzow, PhD, Thomas Hielscher, Thierry Rème, MD, Reinhard Schnettler, Nassim Fard, Katrin Hinderhofer, Paul Theodor Pyl, Wolfgang Huber, PhD, Vladimir Benes, PhD, Anna Marciniak-Czochra, Véronique Pantesco, Anthony D. Ho, MD, Bernard Klein, Jens Hillengass, MD, Dirk Hose, MD
Journal: Blood
Blood (2016) 128 (22): 235.
https://doi.org/10.1182/blood.V128.22.235.235
Published: 2016
Journal Articles

Longitudinal Fluorescence in Situ Hybridization at Primary Diagnosis and Relapse Reveals Clonal Evolution after Autologous Stem Cell Transplantation in Multiple Myeloma

Maximilian Merz, MD, Thomas Hielscher, Anja Seckinger, MD, Dirk Hose, MD, Uta Bertsch, MD, Kai Neben, MD, Marc S Raab, MD, Igor Blau, Hans Walter Lindemann, MD, Ingo GH Schmidt-Wolf, MD, Christof Scheid, MD PhD, Mathias Haenel, MD, Katja Weisel, MD, Hartmut Goldschmidt, MD, Anna Jauch, PhD, Jens Hillengass, MD
Journal: Blood
Blood (2016) 128 (22): 4415.
https://doi.org/10.1182/blood.V128.22.4415.4415
Published: 2016
Journal Articles

Findings of Whole Body Computed Tomography Compared to Conventional Skeletal Survey in Patients with Monoclonal Plasma Cell Disorders - a Study of the International Myeloma Working Group

Jens Hillengass, MD, Lia A. Moulopoulos, MD, Stefan Delorme, MD, Vassilis Koutoulidis, MD, Thomas Hielscher, Jessica Engelhart, Matthew T. Drake, MD PhD, S. Vincent Rajkumar, MD, Brian Oestergaard, MD, Niels Abildgaard, MD Professor, Maja Hinge, MD, Torben Plesner, Professor, Yasuhito Suehara, MD, Kosei Matsue, MD PhD, Jo Caers, Nadia Withofs, MD, Meletios A Dimopoulos, Hartmut Goldschmidt, MD, Suzanne Lentzsch, MD PhD, Brian G Durie, MD, Evangelos Terpos, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4468.
https://doi.org/10.1182/blood.V128.22.4468.4468
Published: 2016
Journal Articles

Clinical Impact of KMT2C and SPRY4 Expression Levels in Intensively Treated Younger Adult Acute Myeloid Leukemia Patients

Sabine Kayser, MD, Maximilian Feszler, Julia Krzykalla, Matthias Schick, Thomas Hielscher, Axel Benner, Michael Kramer, Felicitas Thol, MD, Uwe Platzbecker, MD, Anthony D. Ho, MD, Gerhard Ehninger, MD, Michael Heuser, MD, Christian Thiede, MD, Christoph Röllig, MD, Alwin Krämer, MD
Journal: Blood
Blood (2016) 128 (22): 1663.
https://doi.org/10.1182/blood.V128.22.1663.1663
Published: 2016