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Journal Articles

Impact of Clonal Heterogeneity in Newly Diagnosed, Transplant-Eligible Multiple Myeloma - Subgroup Analysis of the GMMG HD6 Phase III Trial

Maximilian Merz, Ema Pozek, Kaya Miah, Uta Bertsch, Britta Besemer, Mathias Hänel, Julia Krzykalla, Roland Fenk, Jana Schlenzka, Markus Munder, Christine Hanoun, Christoph Mann, Niels Weinhold, Christof Scheid, Roland Schroers, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Christina Kunz, Ivana von Metzler, Aneta Schieferdecker, Jörg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe Martens, Manfred Hensel, Axel Benner, Andrea Seidel-Glätzer, Katja C. Weisel, Marc S. Raab, Hans Salwender, Hartmut Goldschmidt, Elias K. Mai
Journal: Blood
Blood (2024) 144 (Supplement 1): 84.
https://doi.org/10.1182/blood-2024-201972
Published: 2024
Journal Articles

Immunological Subgroups Predicting Efficacy of Elotuzumab in Multiple Myeloma Patients: Insights from the GMMG-HD6 Clinical Trial

Gigi Nu Hoang Quy Ton, Katharina Kriegsmann, Mohamed H.S. Awwad, Axel Benner, Uta Bertsch, Britta Besemer, Mathias Hänel, Roland Fenk, Jana Schlenzka, Markus Munder, Jan Dürig, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Andreas Neubauer, Niels Weinhold, Christof Scheid, Roland Schroers, Ivana von Metzler, Aneta Schieferdecker, Jörg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe Martens, Christian Kunz, Manfred Hensel, Andrea Seidel-Glätzer, Katja Weisel, Hans Salwender, Carsten Müller-Tidow, Marc S. Raab, Hartmut Goldschmidt, Elias K. Mai, Michael Hundemer
Journal: Blood
Blood (2023) 142 (Supplement 1): 1991.
https://doi.org/10.1182/blood-2023-189169
Published: 2023
Journal Articles

Salvage Autologous Transplant and Lenalidomide Maintenance Versus Continuous Lenalidomide/Dexamethasone for Relapsed Multiple Myeloma: Long Term Follow up Results of the Randomized GMMG Phase III Multicenter Trial Relapse

Marc-Andrea Baertsch, Jana Schlenzka, Thomas Hielscher, Marc S. Raab, Sandra Sauer, Maximilian Merz, Elias K. Mai, Carsten Müller-Tidow, Steffen Luntz, Anna Jauch, Peter Brossart, Martin Goerner, Stefan Klein, Bertram Glass, Peter Reimer, Ullrich Graeven, Roland Fenk, Mathias Hänel, Ivana von Metzler, Lindemann Hans W., Christof Scheid, Axel Nogai, Hans Salwender, Richard Noppeney, Britta Besemer, Katja Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2023) 142 (Supplement 1): 782.
https://doi.org/10.1182/blood-2023-178835
Published: 2023
Journal Articles

Implications and Prognostic Impact of Mass Spectrometry in Patients with Newly-Diagnosed Multiple Myeloma

Elias K Mai, Stefanie Huhn, Kaya Miah, Alexandra M Poos, Christof Scheid, Katja Weisel, Uta Bertsch, Markus Munder, Oscar Berlanga, Dirk Hose, Anja Seckinger, Anna Jauch, Igor Wolfgang Blau, Mathias Haenel, Hans Salwender, Axel Benner, Marc S Raab, Hartmut Goldschmidt, Niels Weinhold
Journal: Blood
Blood (2022) 140 (Supplement 1): 2341–2343.
https://doi.org/10.1182/blood-2022-156169
Published: 2022
Journal Articles

Exploring Genetic and Non-Genetic Changes Driving Tumor Evolution in CK-AML at Single-Cell Resolution

Aino-Maija Leppä, Karen Grimes, Hyobin Jeong, Tobias Boch, Darja Karpova, Florian Grünschläger, Anna Jauch, Anna Dolnik, Bernardo Rodriguez-Martin, Lars Bullinger, Alwin Krämer, Ashley D Sanders, Jan O Korbel, Andreas Trumpp
Journal: Blood
Blood (2022) 140 (Supplement 1): 9170–9172.
https://doi.org/10.1182/blood-2022-166007
Published: 2022
Journal Articles

Isatuximab, Carfilzomib, Lenalidomide, and Dexamethasone (Isa-KRd) in Patients with High-Risk Newly Diagnosed Multiple Myeloma: Planned Interim Analysis of the GMMG-Concept Trial

Katja Weisel, Britta Besemer, Mathias Haenel, Raphael Lutz, Christoph Mann, Markus Munder, Martin Goerner, Hans Christian Reinhardt, Axel Nogai, Yon-Dschun Ko, Maike De Wit, Hans Salwender, Christoph Scheid, Ullrich Graeven, Rudolf Peceny, Peter Staib, Annette Dieing, Anna Jauch, Manola Zago, Axel Benner, Diana Tichy, Carsten Bokemeyer, Hartmut Goldschmidt, Lisa B. Leypoldt
Journal: Blood
Blood (2022) 140 (Supplement 1): 1836–1838.
https://doi.org/10.1182/blood-2022-156309
Published: 2022
Journal Articles

Bone Marrow Immune Signatures in Multiple Myeloma Are Linked to Tumor Heterogeneity and Treatment Outcome

Simon Steiger, Raphael Lutz, Nina Prokoph, Subarna Palit, Stephan M Tirier, Philipp Reichert, Anja Baumann, Nadine Hefner, Sabrina Schumacher, Dominik Vonficht, Florian Grünschläger, Alexandra M Poos, Lukas John, Laleh Haghverdi, Jan-Philipp Mallm, Elias K Mai, Mirco Friedrich, Katharina Kriegsmann, Mohamed H.S. Awwad, Anna Jauch, Uta Bertsch, Diana Tichy, Carsten Müller-Tidow, Roland Schroers, Hans Salwender, Britta Besemer, Roland Fenk, Katja Weisel, Hartmut Goldschmidt, Stefanie Huhn, Michael Hundemer, Karsten Rippe, Simon Haas, Niels Weinhold, Marc S Raab
Journal: Blood
Blood (2022) 140 (Supplement 1): 2083–2085.
https://doi.org/10.1182/blood-2022-168685
Published: 2022
Journal Articles

Elotuzumab in Combination with Lenalidomide, Bortezomib, Dexamethasone and Autologous Transplantation for Newly-Diagnosed Multiple Myeloma: Results from the Randomized Phase III GMMG-HD6 Trial

Hartmut Goldschmidt, Elias K Mai, Uta Bertsch, Britta Besemer, Mathias Haenel, Kaya Miah, Roland Fenk, Jana Schlenzka, Markus Munder, Jan Dürig, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Christina Kunz, Andreas Neubauer, Christof Scheid, Roland Schroers, Ivana v. Metzler, Aneta Schieferdecker, Joerg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe M. Martens, Christian Kunz, Manfred Hensel, Andrea Seidel-Glaetzer, Katja Weisel, Marc-Steffen Raab, Hans Salwender
Journal: Blood
Blood (2021) 138 (Supplement 1): 486.
https://doi.org/10.1182/blood-2021-147323
Published: 2021
Journal Articles

Gain 1q21 Is an Adverse Prognostic Factor in Patients with Relapsed/Refractory AL Amyloidosis Treated with Lenalidomide and Dexamethasone

Marco Basset, MD, Christoph Kimmich, Tobias Dittrich, MD, Kaya Veelken, MD, Hartmut Goldschmidt, MD, Dirk Hose, MD, Anja Seckinger, MD, Anna Jauch, Carsten Mueller-Tidow, MD, Ute Hegenbart, MD, Stefan Schönland, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17–18.
https://doi.org/10.1182/blood-2020-142701
Published: 2020
Journal Articles

Daratumumab for systemic AL amyloidosis: prognostic factors and adverse outcome with nephrotic-range albuminuria

Clinical Trials & Observations
Christoph R. Kimmich, Tobias Terzer, Axel Benner, Tobias Dittrich, Kaya Veelken, Alexander Carpinteiro, Timon Hansen, Hartmut Goldschmidt, Anja Seckinger, Dirk Hose, Anna Jauch, Stefan Wörner, Jörg Beimler, Carsten Müller-Tidow, Ute Hegenbart, Stefan O. Schönland
Journal: Blood
Blood (2020) 135 (18): 1517–1530.
https://doi.org/10.1182/blood.2019003633
Published: 2020
Includes: Supplemental data
Journal Articles

Bortezomib-Based Induction and Maintenance Overcomes the Negative Prognostic Impact of Renal Impairment and del17p in Transplant-Eligible Myeloma Patients: Long Term Results from the Phase III HOVON-65/GMMG-HD4 Study after Median 137 Months Follow up

Christof Scheid, MD, Henk Lokhorst, MD PhD, Igor W Blau, MD PhD, Bronno Van Der Holt, PhD, Uta Bertsch, Sonja Zweegman, MD PhD, Katja Weisel, Edo Vellenga, Marie José Kersten, MD PhD, Sandra Croockewit, Elias K Mai, MD, Reinier Raymakers, MD PhD, Dirk Hose, MD, Anna Jauch, Jens Hillengass, MD, Marian Stevens-Kroef, PhD, Marc S Raab, MD PhD, Kai Neben, Stephan Stilgenbauer, Annemiek Broyl, MD PhD, Hans-Walter Lindemann, MD, Gerard Bos, MD PhD, Peter Brossart, MD, Marinus van Marwijk Kooij, MD PhD, Paula F Ypma, MD PhD, Ulrich Dührsen, Prof, MD PhD, Ron Schaafsma, MD PhD, Thomas Hielscher, Hans Salwender, Hartmut Goldschmidt, MD, Pieter Sonneveld
Journal: Blood
Blood (2019) 134 (Supplement_1): 3308.
https://doi.org/10.1182/blood-2019-129684
Published: 2019
Journal Articles

Easix for Prediction of Survival in Myelodysplastic Syndromes

Almuth Maria Anni Merz, MD, Ulrich Germing, MD, Guido Kobbe, MD, Jennifer Kaivers, MD, Anna Jauch, Aleksandar Radujkovic, MD, Manuela Hummel, Axel Benner, Maximilian Merz, Peter Dreger, Thomas Luft, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1722.
https://doi.org/10.1182/blood-2019-122622
Published: 2019
Journal Articles

Treatment Response and Long-Term Survival in Multiple Myeloma in the GMMG-HD4 Trial - Neither Profit All Molecular Entities Alike, Nor Are Remissions to Different Regimen Equal

Anja Seckinger, Hans Jürgen Salwender, MD, Hans Martin, MD, Christof Scheid, Thomas Hielscher, Uta Bertsch, MD, Manuela Hummel, Anna Jauch, PhD, Wolfgang Knauf, Martina Emde, Susanne Beck, Kai Neben, Henk M. Lokhorst, MD PhD, Bronno van der Holt, PhD, Ulrich Duehrsen, MD, Jan Dürig, Hans-Walter Lindemann, MD, Ingo Schmidt-Wolf, Mathias Haenel, MD, Bernd Lathan, Marc S Raab, MD PhD, Carsten Müller-Tidow, MD, Pieter Sonneveld, MD PhD, Igor Wolfgang Blau, Jens Hillengass, MD, Katja Weisel, MD, Hartmut Goldschmidt, MD, Dirk Hose, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4485.
https://doi.org/10.1182/blood-2018-99-113284
Published: 2018
Journal Articles

AL Amyloidosis — Pathogenesis and Prognosis Are Determined By the Amyloidogenic Potential of the Light Chain and the Molecular Characteristics of Malignant Plasma Cells

Anja Seckinger, Ute Hegenbart, Susanne Beck, Martina Emde, Tilmann Bochtler, Christoph Kimmich, Carsten Müller-Tidow, MD, Anna Jauch, PhD, Stefan Schönland, Dirk Hose, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 187.
https://doi.org/10.1182/blood-2018-187
Published: 2018
Journal Articles

Salvage Autologous Transplant and Lenalidomide Maintenance Versus Continuous Lenalidomide/Dexamethasone for Relapsed Multiple Myeloma: Results of the Randomized GMMG Phase III Multicenter Trial Relapse

Hartmut Goldschmidt, MD, Marc-A. Baertsch, MD, Jana Schlenzka, MD, Natalia Becker, PhD, Habermehl Christina, PhD, Thomas Hielscher, Marc S Raab, MD, Jens Hillengass, MD, Carsten Müller-Tidow, MD, Steffen Luntz, MD, Anna Jauch, PhD, Peter Brossart, MD, Martin Goerner, MD, Stefan A Klein, MD, Martin Schmidt-Hieber, MD PhD, Peter Reimer, MD, Ullrich Graeven, MD, Roland Fenk, MD PhD, Mathias Haenel, MD, Hans Martin, MD, Hans-Walter Lindemann, MD, Christoph Scheid, MD, Axel Nogai, MD, Hans Jürgen Salwender, MD, Richard Noppeney, MD, Katja Weisel, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 253.
https://doi.org/10.1182/blood-2018-99-111203
Published: 2018
Journal Articles

Subgroup Analyses of the Randomized GMMG Phase III Multicenter Trial Relapse Suggest Survival Benefit of Salvage Autologous Transplant Primarily in Low Risk Multiple Myeloma

Marc-A. Baertsch, MD, Jana Schlenzka, MD, Habermehl Christina, PhD, Thomas Hielscher, Marc S Raab, MD, Jens Hillengass, MD, Carsten Müller-Tidow, MD, Steffen Luntz, MD, Anna Jauch, PhD, Peter Brossart, MD, Martin Goerner, MD, Stefan A Klein, MD, Martin Schmidt-Hieber, MD PhD, Peter Reimer, MD, Ullrich Graeven, MD, Roland Fenk, MD PhD, Mathias Haenel, MD, Hans Martin, MD, Hans-Walter Lindemann, MD, Christoph Scheid, MD, Axel Nogai, MD, Hans Jürgen Salwender, MD, Richard Noppeney, MD, Katja Weisel, MD, Hartmut Goldschmidt, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 254.
https://doi.org/10.1182/blood-2018-99-119762
Published: 2018
Journal Articles

A Predictive Score for Early Mortality during Induction Therapy in Newly Diagnosed Transplant-Eligible Multiple Myeloma - an Analysis from Five GMMG and HOVON Multicenter Phase III Trials

Elias K Mai, MD, Thomas Hielscher, PhD, Uta Bertsch, MD, Jana Schlenzka, MD, Hans Jürgen Salwender, Henk M Lokhorst, Markus Munder, MD, Bronno van der Holt, Christian Gerecke, MD, Michael Pfreundschuh, MD, Ulrich Duhrsen, Peter Brossart, MD, Sonja Zweegman, MD PhD, Kai Neben, Jens Hillengass, MD, Marc-Steffen S Raab, Dirk Hose, MD, Edo Vellenga, MD, Maximilian Merz, MD, Iris Breitkreutz, MD, Anna Jauch, Marie José Kersten, MD, Hans Martin, Hans-Walter Lindemann, Norma Peter, MD, Sandra Croockewit, MD, Igor Wolfgang Blau, MD, Christof Scheid, MD, Katja C. Weisel, Pieter Sonneveld, MDPhD, Hartmut Goldschmidt, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2016.
https://doi.org/10.1182/blood.V130.Suppl_1.2016.2016
Published: 2017
Journal Articles

Response-Adapted Lenalidomide Maintenance in Newly Diagnosed, Transplant-Eligible Multiple Myeloma: Results from the Multicenter Phase III GMMG-MM5 Trial

Hartmut Goldschmidt, MD, Elias K Mai, MD, Jan Dürig, MD, Christof Scheid, MD, Katja C. Weisel, Christina Kunz, Uta Bertsch, MD, Thomas Hielscher, PhD, Markus Munder, MD, Hans-Walter Lindemann, Barbara Huegle-Doerr, Dirk Hose, MD, Anja Seckinger, Stefanie Huhn, PhD, Anna Jauch, Bernhard Rabold, Ahmet Elmaagacli, MD, Christian Gerecke, MD, Peter Brossart, MD, Martin Goerner, MD, Helga Bernhard, MD, Martin Hoffmann, MD, Jens Hillengass, MD, Marc-Steffen S Raab, Igor Wolfgang Blau, MD, Mathias Hänel, MD, Hans Jürgen Salwender
Journal: Blood
Blood (2017) 130 (Supplement 1): 400.
https://doi.org/10.1182/blood.V130.Suppl_1.400.400
Published: 2017
Journal Articles

Comprehensive Genomic Characterization of Refractory Multiple Myeloma Reveals a Complex Mutational and Structural Landscape Associated with Drug Resistance

Nicola Lehners, MD, Umut H Toprak, Jing Xu, Nagarajan Paramasivam, Daniel Hübschmann, Martina Fröhlich, Nur H Md Hanafiah, Sadaf Mughal, Elias K Mai, MD, Anna Jauch, Jens Hillengass, MD, Roland Eils, Carsten Müller-Tidow, Benedikt Brors, Hartmut Goldschmidt, MD, Matthias Schlesner, Marc S Raab, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 266.
https://doi.org/10.1182/blood.V130.Suppl_1.266.266
Published: 2017
Journal Articles

Direct Assessment of IgA and IgG Paraprotein By Hevylite Assay and Correlation to IMWG Response and Progression-Free Survival in Newly Diagnosed, Transplant-Eligible Multiple Myeloma Patients in the Prospective Phase III GMMG-MM5 Trial

Christof Scheid, MD, Anja Seckinger, Jan Dürig, MD, Katja C. Weisel, Christina Kunz, Uta Bertsch, MD, Thomas Hielscher, PhD, Markus Munder, MD, Hans-Walter Lindemann, Barbara Huegle-Doerr, Stefanie Huhn, PhD, Elias K Mai, MD, Anna Jauch, Bernhard Rabold, Christian Gerecke, MD, Peter Brossart, MD, Martin Goerner, MD, Helga Bernhard, MD, Martin Hoffmann, MD, Jens Hillengass, MD, Marc-Steffen S Raab, Igor Wolfgang Blau, MD, Mathias Haenel, Dirk Hose, MD, Hartmut Goldschmidt, MD, Hans Jürgen Salwender
Journal: Blood
Blood (2017) 130 (Supplement 1): 1784.
https://doi.org/10.1182/blood.V130.Suppl_1.1784.1784
Published: 2017