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Darja Karpova
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Journal Articles

Frequent Whole Blood Donations Select for DNMT3A variants Mediating Enhanced Response to Erythropoietin

Darja Karpova, Hector Huerga Encabo, Elisa Donato, Iuliia Kotova, Silvia Calderazzo, Aino-Maija Leppä, Panten Jasper, Adriana Przybylla, Erhard Seifried, Annette Kopp-Schneider, Terrence N Wong, Dominique Bonnet, Halvard Bonig, Andreas Trumpp
Journal: Blood
Blood (2022) 140 (Supplement 1): 8605–8606.
https://doi.org/10.1182/blood-2022-167821
Published: 2022
Journal Articles

Exploring Genetic and Non-Genetic Changes Driving Tumor Evolution in CK-AML at Single-Cell Resolution

Aino-Maija Leppä, Karen Grimes, Hyobin Jeong, Tobias Boch, Darja Karpova, Florian Grünschläger, Anna Jauch, Anna Dolnik, Bernardo Rodriguez-Martin, Lars Bullinger, Alwin Krämer, Ashley D Sanders, Jan O Korbel, Andreas Trumpp
Journal: Blood
Blood (2022) 140 (Supplement 1): 9170–9172.
https://doi.org/10.1182/blood-2022-166007
Published: 2022
Journal Articles

Targeting CXCR4, VLA4, and CXCR2 for Hematopoietic Stem Cell Mobilization

Daniel Cancilla, BS, Haresh Thakellapalli, Marvin J Meyers, PhD, Michael P. Rettig, PhD, Ezhilarasi Chendamarai, PhD, Stephanie Christ, MS, Darja Karpova, PhD, Peter G Ruminski, BS, Julie K. Ritchey, Dwight M. Morrow, PhD, Michael Prinsen, John F. DiPersio, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1916.
https://doi.org/10.1182/blood-2019-124373
Published: 2019
Journal Articles

Generation and Characterization of Novel VLA-4 Inhibitors for Stem Cell Mobilization in Combination with a CXCR2 Agonist

Moses O. Evbuomwan, Richard F Heier, BS, Darja Karpova, PhD, Stephanie Christ, MS, Ezhilarasi Chendamarai, PhD, Michael P Rettig, PhD, Linda G Eissenberg, PhD, Stacy D Arnett, PhD, Julie Ritchey, Marvin J Meyers, PhD, Peter G Ruminski, BS, David W Griggs, PhD, Dwight Morrow, PhD, John F DiPersio, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3197.
https://doi.org/10.1182/blood.V130.Suppl_1.3197.3197
Published: 2017
Journal Articles

Continuous blockade of CXCR4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cells

Darja Karpova, Julie K. Ritchey, Matthew S. Holt, Grazia Abou-Ezzi, Darlene Monlish, Lena Batoon, Susan Millard, Gabriele Spohn, Eliza Wiercinska, Ezhil Chendamarai, Wei Yang, Stephanie Christ, Leah Gehrs, Laura G. Schuettpelz, Klaus Dembowsky, Allison R. Pettit, Michael P. Rettig, Halvard Bonig, John F. DiPersio
Journal: Blood
Blood (2017) 129 (21): 2939–2949.
https://doi.org/10.1182/blood-2016-10-746909
Published: 2017
Includes: Supplemental data
Journal Articles

Expansion and Maintenance of Hematopoietic Stem and Progenitor Cells in Course of Long-Term Inhibition of CXCR4/CXCL12 Signaling

Darja Karpova, PhD, Julie Ritchey, Matthew Holt, Darlene Monlish, PhD, Laura G. Schuettpelz, MD PhD, Wei Yang, Jean-Pierre Levesque, PhD, Allison Robyn Pettit, PhD BSc, Michael P. Rettig, PhD, Halvard Bonig, MD MA, John F DiPersio, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2648.
https://doi.org/10.1182/blood.V128.22.2648.2648
Published: 2016
Journal Articles

Combined Targeting of CXCR2 and VLA4 Results in Rapid and Synergistic Mobilization of Hematopoietic Stem and Progenitor Cells in Mice

Darja Karpova, PhD, Michael P. Rettig, PhD, Linda Eissenberg, PhD, Julie Ritchey, Matthew Holt, Richard Heier, Stacy Arnett, PhD, Marvin Meyers, PhD, David W. Griggs, PhD, Peter Ruminski, PhD, Dwight Morrow, PhD, John F DiPersio, MD PhD
Journal: Blood
Blood (2016) 128 (22): 659.
https://doi.org/10.1182/blood.V128.22.659.659
Published: 2016
Journal Articles

Targeting CD123 in acute myeloid leukemia using a T-cell–directed dual-affinity retargeting platform

Muneera Al-Hussaini, Michael P. Rettig, Julie K. Ritchey, Darja Karpova, Geoffrey L. Uy, Linda G. Eissenberg, Feng Gao, William C. Eades, Ezio Bonvini, Gurunadh R. Chichili, Paul A. Moore, Syd Johnson, Lynne Collins, John F. DiPersio
Journal: Blood
Blood (2016) 127 (1): 122–131.
https://doi.org/10.1182/blood-2014-05-575704
Published: 2016
Includes: Supplemental data
Journal Articles

Potent Stem Cell Mobilization with the Novel CXCR4 Antagonist POL6326 - Results of a Phase IIa Dose Escalation Study in Comparison to G-CSF

Darja Karpova, PhD, Susanne Brauninger, MD, Eliza Wiercinska, PhD, Ariane Kraemer, B.Sc., Belinda Stock, Jochen Graff, MD, Christophe Escot, Garry Douglas, PhD, Barbara Romagnoli, PhD, Eric Chevalier, PhD, Klaus Dembowsky, MD PhD, Leon Hooftman, MD, Halvard Bonig, MD MA
Journal: Blood
Blood (2015) 126 (23): 511.
https://doi.org/10.1182/blood.V126.23.511.511
Published: 2015
Journal Articles

Rapid and Potent Mobilization of Murine Hematopoietic Stem and Progenitor Cells by the Novel CXCR4 Antagonist POL5551

Darja Karpova, M.Sc., Katrin Dauber, Dipl.biol., Gabriele Spohn, Ph.D., Doreen Chudziak, Dipl.biol., Eliza Wiercinska, Miriam Schulz, Barbara Romagnoli, Eric Chevalier, PhD, Kalpana Patel, Halvard Bonig, MD, MA
Journal: Blood
Blood (2012) 120 (21): 4100.
https://doi.org/10.1182/blood.V120.21.4100.4100
Published: 2012
Journal Articles

GRK6 Ablation Is Associated with Surprisingly Modest Effects on Immature Hematopoiesis

Doreen Chudziak, Dipl.biol., Gabriele Spohn, Ph.D., Katrin Dauber, Dipl.biol., Darja Karpova, M.Sc., Halvard Bonig, MD, MA
Journal: Blood
Blood (2011) 118 (21): 2381.
https://doi.org/10.1182/blood.V118.21.2381.2381
Published: 2011