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Maximilian Merz
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Journal Articles

The Differences between Ide-Cel and Cilta-Cel in Relapsed Myeloma at Single Cell Resolution

David Fandrei, Michael Rade, Markus Kreuz, Luise Fischer, Patrick Born, Sabine Seiffert, Andreas Boldt, Jonathan Scolnick, Lakshmi Venkatraman, Stacy Xu, Ronny Baber, Song Yau Wang, Enrica Bach, Sandra Hoffmann, Klaus H Metzeler, Marco Herling, Madlen Jentzsch, Georg-Nikolaus Franke, Ulrike Köhl, Uwe Platzbecker, Vladan Vucinic, Kristin Reiche, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 1877.
https://doi.org/10.1182/blood-2024-210746
Published: 2024
Journal Articles

Impact of Clonal Heterogeneity in Newly Diagnosed, Transplant-Eligible Multiple Myeloma - Subgroup Analysis of the GMMG HD6 Phase III Trial

Maximilian Merz, Ema Pozek, Kaya Miah, Uta Bertsch, Britta Besemer, Mathias Hänel, Julia Krzykalla, Roland Fenk, Jana Schlenzka, Markus Munder, Christine Hanoun, Christoph Mann, Niels Weinhold, Christof Scheid, Roland Schroers, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Christina Kunz, Ivana von Metzler, Aneta Schieferdecker, Jörg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe Martens, Manfred Hensel, Axel Benner, Andrea Seidel-Glätzer, Katja C. Weisel, Marc S. Raab, Hans Salwender, Hartmut Goldschmidt, Elias K. Mai
Journal: Blood
Blood (2024) 144 (Supplement 1): 84.
https://doi.org/10.1182/blood-2024-201972
Published: 2024
Journal Articles

Measurable Residual Disease Detection of IDH1 or IDH2 Mutations Post but Not Prior to Allogeneic Hematopoietic Stem Cell Transplantation Show High Prognostic Relevance in Patients with Acute Myeloid Leukemia

Jacob Jendro, Lara Bischof, Jule Ussmann, Tung Pham Thanh, Donata Backhaus, Dominic Brauer, Vladan Vucinic, Carmen Herling, Marco Herling, Georg-Nikolaus Franke, Maximilian Merz, Klaus H Metzeler, Uwe Platzbecker, Sebastian Schwind, Madlen Jentzsch
Journal: Blood
Blood (2024) 144 (Supplement 1): 4334.
https://doi.org/10.1182/blood-2024-207490
Published: 2024
Journal Articles

Efficacy of Anti-BCMA CAR-T Cell Therapies in Multiple Myeloma Patients with Prior Exposure to Bispecific Antibodies- Results from a Retrospective Multi-Center Registry Analysis

Johannes Waldschmidt, David Fandrei, Vladan Vucinic, Ralph Wäsch, Axel Nogai, Winfried Alsdorf, Annamaria Brioli, Evgenii Shumilov, Fabian Mueller, Raphael Teipel, Nico Gagelmann, Monika Engelhardt, Jan Krönke, Julia Mersi, Michael Hudecek, Martin K. Kortüm, Uwe Platzbecker, Hermann Einsele, Max S. Topp, Leo Rasche, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2007.
https://doi.org/10.1182/blood-2024-210451
Published: 2024
Journal Articles

Cilta-Cel Is Associated with Improved Outcomes and Distinct Cellular Dynamics Compared with Ide-Cel for Relapsed or Refractory Multiple Myeloma

Nico Gagelmann, Friedrich Stölzel, Roland Fenk, Tobias A.W. Holderried, Fabian Mueller, Natalia Tovar, Aina Oliver-Caldés, Kristin Rathje, Vladan Vucinic, Soraya Kharboutli, Ben-Niklas Bärmann, Francis A. Ayuk, Uwe Platzbecker, Anca Maria Albici, Natalie Schub, Friederike Schmitz, Cyrus Khandanpour, Marcel Teichert, Barbara Jeker, Nicolaus Kroeger, Bastian von Tresckow, Carlos Fernandez de Larrea, Thomas Pabst, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2003.
https://doi.org/10.1182/blood-2024-211410
Published: 2024
Journal Articles

Predicting Progression Events in Multiple Myeloma from Routine Blood Work

Maximilian Ferle, Nora Grieb, Markus Kreuz, Uwe Platzbecker, Thomas Neumuth, Kristin Reiche, Alexander Oeser, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 7476.
https://doi.org/10.1182/blood-2024-192951
Published: 2024
Journal Articles

Prognostic Value of Baseline and Early Response FDG-PET/CT Combined with Cellular Dynamics in Patients with Refractory and Relapsed Mantle Cell Lymphoma (MCL) Undergoing Chimeric Antigen Receptor (CAR)-T Cell Therapy

Simon M Krauß, Sabine Seiffert, Carmen Perez Fernandez, Thomas Walter Georgi, Janine Kirchberg, Enrica Bach, Mandy Brueckner, Madlen Jentzsch, Carmen Herling, Maximilian Merz, Klaus H Metzeler, Marco Herling, Georg-Nikolaus Franke, Andreas Boldt, Solveig Tiepolt, Regine Kluge, Ulrike Koehl, Timm Denecke, Osama Sabri, Ulrich Sack, Uwe Platzbecker, Lars Kurch, Vladan Vucinic
Journal: Blood
Blood (2024) 144 (Supplement 1): 6343.
https://doi.org/10.1182/blood-2024-206686
Published: 2024
Journal Articles

Single Vs. Tandem Autologous Stem Cell Transplantation in Newly Diagnosed Multiple Myeloma: A Real-World Multi-Center Study from the German Registry for Hematopoietic Stem Cell Transplantation and Cell Therapy (DRST)

Nora Grieb, Alexander Oeser, Maximilian Ferle, Franziska Hanke, Sarah Flossdorf, Sandra Sauer, Hartmut Goldschmidt, Carsten Müller-Tidow, Hans Salwender, Roland Fenk, Monika Engelhardt, Robert Zeiser, Vladan Vucinic, Georg-Nikolaus Franke, Igor Wolfgang Blau, Daniel Teschner, Hermann Einsele, Christoph Richard Kimmich, Miriam Kull, Britta Besemer, Nico Gagelmann, Nicolaus Kröger, Thomas Neumuth, Uwe Platzbecker, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 708.
https://doi.org/10.1182/blood-2024-198638
Published: 2024
Journal Articles

Persistent Thrombocytopenia and Neutropenia Are Associated with Increased Mortality in Patients Treated with Anti-BCMA CAR T Cells for Relapsed/Refractory Multiple Myeloma

Thomas C Wiemers, David Fandrei, Sabine Seiffert, Michael Rade, Susanne Rieprecht, Patrick Born, Markus Kreuz, Luise Fischer, Ronny Baber, Song Yau Wang, Enrica Bach, Sandra Hoffmann, Klaus H Metzeler, Marco Herling, Madlen Jentzsch, Georg-Nikolaus Franke, Ulrike Köhl, Maik Friedrich, Andreas Boldt, Kristin Reiche, Uwe Platzbecker, Vladan Vucinic, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 7095.
https://doi.org/10.1182/blood-2024-202101
Published: 2024
Journal Articles

CT-Based Muscle Quality and Visceral Obesity Prior to Allogeneic Hematopoietic Stem Cell Transplantation Is of Prognostic Relevance in Patients with Acute Myeloid Leukemia

Jule Ussmann, Clara Wall, Lara Bischof, Jacob Jendro, Dominic Brauer, Donata Backhaus, Klaus H Metzeler, Marco Herling, Carmen Herling, Vladan Vucinic, Georg-Nikolaus Franke, Maximilian Merz, Timm Denecke, Uwe Platzbecker, Sebastian Schwind, Hans-Jonas Meyer, Madlen Jentzsch
Journal: Blood
Blood (2024) 144 (Supplement 1): 2158.
https://doi.org/10.1182/blood-2024-199943
Published: 2024
Journal Articles

Cellular Composition and Clinical Factors Influencing Manufacturing Outcomes for Anti-BCMA CAR T Cell Therapy in a Large Real-World Cohort of Relapsed/Refractory Multiple Myeloma

Vladan Vucinic, David Fandrei, Janine Kirchberg, Enrica Bach, Mandy Brueckner, Kathleen Friedrich, Carmen Herling, Madlen Jentzsch, Georg-Nikolaus Franke, Simone Heyn, Uwe Platzbecker, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2094.
https://doi.org/10.1182/blood-2024-207117
Published: 2024
Journal Articles

Prevalence and Mutational Make-up of Secondary Hematologic Neoplasms in Multiple Myeloma Patients after CAR-T Cell Therapy

Johannes Waldschmidt, Maximilian Merz, Judith S. Hecker, Franz Reinhard, Benjamin GT Shibru, Marion Hoegner, Anna Gebauer, David Fandrei, Manja Meggendorfer, Marietta Truger, Johannes Jung, Daniel Teschner, Max S. Topp, Anna Purcarea, Vladan Vucinic, Martin K. Kortüm, Torsten Haferlach, Florian Bassermann, Uwe Platzbecker, Hermann Einsele, Claudia Haferlach, Klaus H Metzeler, Katharina S. S. Götze, Leo Rasche
Journal: Blood
Blood (2024) 144 (Supplement 1): 4688.
https://doi.org/10.1182/blood-2024-210233
Published: 2024
Journal Articles

Single Cell Multi-Omic Dissection of Response and Resistance to Chimeric Antigen Receptor T Cells Against BCMA in Relapsed Multiple Myeloma

Maximilian Merz, Luise Fischer, Jaren Sia, Patrick Born, Ronald Weiss, Nora Grieb, Michael Rade, Andreas Boldt, Stephan Fricke, Paul Franz, Jonathan Scolnick, Lakshmi Venkatraman, Stacy Xu, Christina Kloetzer, Simone Heyn, Anne Sophie Kubasch, Ronny Baber, Song Yau Wang, Enrica Bach, Sandra Hoffmann, Jule Ussmann, Klaus H Metzeler, Marco Herling, Carmen Herling, Madlen Jentzsch, Georg-Nikolaus Franke, Ulrich Sack, Ulrike Koehl, Kristin Reiche, Uwe Platzbecker, Vladan Vucinic
Journal: Blood
Blood (2023) 142 (Supplement 1): 453.
https://doi.org/10.1182/blood-2023-187371
Published: 2023
Journal Articles

Apheresis for Production of Chimeric Antigen Receptor (CAR) T Cells in Patients with Multiple Myeloma - Clinical Factors, Cell Composition and T Cell Senescence

Vladan Vucinic, Janine Kirchberg, Mandy Brueckner, Patrick Born, Luise Fischer, Enrica Bach, Nora Grieb, Simone Heyn, Christina Kloetzer, Klaus H Metzeler, Sandra Hoffmann, Carmen Herling, Marco Herling, Georg-Nikolaus Franke, Sebastian Schwind, Song-Yau Wang, Madlen Jentzsch, Uwe Platzbecker, Maximilian Merz
Journal: Blood
Blood (2023) 142 (Supplement 1): 3521.
https://doi.org/10.1182/blood-2023-182222
Published: 2023
Journal Articles

Increased Bone Turnover and Decreased BCMA Levels in Patients with Response to Anti-BCMA CAR T Cell Therapy in Relapsed/Refractory Multiple Myeloma

Jule Ussmann, Luise Fischer, Patrick Born, Nora Grieb, Sandra Hoffmann, Ronny Baber, Song-Yau Wang, Christina Kloetzer, Simone Heyn, Marco Herling, Carmen Herling, Madlen Jentzsch, Georg-Nikolaus Franke, Lorenz Hofbauer, Uwe Platzbecker, Vladan Vucinic, Heike Weidner, Maximilian Merz
Journal: Blood
Blood (2023) 142 (Supplement 1): 6643.
https://doi.org/10.1182/blood-2023-185643
Published: 2023
Journal Articles

Real-World Analysis of Teclistamab in 115 RRMM Patients from Germany

Christine Riedhammer, Florian Bassermann, Britta Besemer, Moritz Bewarder, Franziska Brunner, Alexander Carpinteiro, Hermann Einsele, Josefine Faltin, Jan Frenking, Deniz Gezer, Sarah Goldman-Mazur, Mathias Hanel, Marion Hoegner, K. Martin Kortüm, Jan Krönke, Miriam Kull, Theo Leitner, Christoph Mann, Rabea Mecklenbrauck, Maximilian Merz, Anke Morgner, Axel Nogai, Marc S. Raab, Raphael Teipel, Ralph Wäsch, Leo Rasche
Journal: Blood
Blood (2023) 142 (Supplement 1): 3329.
https://doi.org/10.1182/blood-2023-180032
Published: 2023
Journal Articles

Cellular Dynamics Following CAR T Cell Therapy Are Associated with Response, Resistance and Cytokine Release Syndrome in Relapsed/Refractory Multiple Myeloma

Luise Fischer, Patrick Born, Ronald Weiss, Nora Grieb, Sabine Seiffert, Andreas Boldt, Stephan Fricke, Paul Franz, Christina Kloetzer, Simone Heyn, Ronny Baber, Song-Yau Wang, Enrica Bach, Sandra Hoffmann, Jule Ussmann, Janine Kirchberg, Klaus H Metzeler, Marco Herling, Madlen Jentzsch, Georg-Nikolaus Franke, Ulrich Sack, Kristin Reiche, Ulrike Koehl, Uwe Platzbecker, Vladan Vucinic, Maximilian Merz
Journal: Blood
Blood (2023) 142 (Supplement 1): 1008.
https://doi.org/10.1182/blood-2023-188367
Published: 2023
Journal Articles

Impact of Typical and Atypical Complex Karyotype Subgroups on Outcome of AML Patients Undergoing Allogeneic Stem Cell Transplantation

Jule Ussmann, Anne Weigert, Lara Bischof, Dominic Brauer, Donata Backhaus, Claudia Diener, Maximilian Merz, Vladan Vucinic, Klaus H Metzeler, Uwe Platzbecker, Sebastian Schwind, Madlen Jentzsch
Journal: Blood
Blood (2023) 142 (Supplement 1): 2244.
https://doi.org/10.1182/blood-2023-179713
Published: 2023
Journal Articles

Salvage Autologous Transplant and Lenalidomide Maintenance Versus Continuous Lenalidomide/Dexamethasone for Relapsed Multiple Myeloma: Long Term Follow up Results of the Randomized GMMG Phase III Multicenter Trial Relapse

Marc-Andrea Baertsch, Jana Schlenzka, Thomas Hielscher, Marc S. Raab, Sandra Sauer, Maximilian Merz, Elias K. Mai, Carsten Müller-Tidow, Steffen Luntz, Anna Jauch, Peter Brossart, Martin Goerner, Stefan Klein, Bertram Glass, Peter Reimer, Ullrich Graeven, Roland Fenk, Mathias Hänel, Ivana von Metzler, Lindemann Hans W., Christof Scheid, Axel Nogai, Hans Salwender, Richard Noppeney, Britta Besemer, Katja Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2023) 142 (Supplement 1): 782.
https://doi.org/10.1182/blood-2023-178835
Published: 2023
Journal Articles

Collections of Autologous Lymphocytes for Treatment with Chimeric Antigen Receptor (CAR) T-Lymphocytes - No Association of Clonal Hematopoiesis (CH) with Manufacturing Success

Simon M. Krauss, Konstantin Weibl, Enrica Bach, Mandy Brückner, Anne Weigert, Theresa Tumewu, Florian Ramdohr, Elena Ruschpler, Gunhild Vogtmann, Sandra Hoffmann, Olaf Penack, Martin Janz, Raymund Buhmann, Reinhard Henschler, Lars Bullinger, Ulrich Keller, Sebastian Schwind, Maximilian Merz, Madlen Jentzsch, Georg-Nikolaus Franke, Marco Herling, Uwe Platzbecker, Klaus H. Metzeler, Vladan Vucinic
Journal: Blood
Blood (2022) 140 (Supplement 1): 7560–7562.
https://doi.org/10.1182/blood-2022-163360
Published: 2022