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Journal Articles

Prolonged cytopenias after BCMA CAR‑T are associated with impaired endogenous T cell recovery characterized by decreased CD8+ T cell diversity

Free
Abigail Chutnik, Zachary Avigan, Ramy Mahmoud, Alessandro Lagana, Matthew Croken, Meenakshi Mehrotra, Zahra Moinfar, Adriana Rossi, Shambavi Richard, Gurbakhash Kaur, Joshua Richter, Larysa Sanchez, Cesar Rodriguez Valdes, Hearn Cho, Sundar Jagannath, Mesude Bicak, Nina Bhardwaj, Jane Houldsworth, Santiago Thibaud, Samir Parekh
Journal: Blood
Blood (2025) 146 (Supplement 1): 2290.
https://doi.org/10.1182/blood-2025-2290
Published: 2025
Journal Articles

Real world outcomes of bispecific T-cell engagers in plasma cell leukemia

Free
Mahmoud Gaballa, Kelley Julian, Aimaz Afrough, Doris Hansen, Utkarsh Goel, Andre De Menezes Silva Corraes, Danai Dima, Masooma Rana, Hitomi Hosoya, Lekha Mikkilineni, Lindsay Fogel, Shahzad Raza, Rahul Banerjee, Saurabh Zanwar, Oren Pasvolsky, Aishwarya Sannareddy, Azra Borogovac, James Davis, Kimberly Green, Noa Biran, Megan Herr, Leyla Shune, Evguenia Bhurtel, Shebli Atrash, Christopher Ferreri, Tiffany Richards, Muhammad Bilal Abid, Susan Bal, Hossam M. Ali, J Christine Ye, Shambavi Richard, Gurbakhash Kaur, Kenneth Shain, Omar Alexis Castaneda Puglianini, Adriana Rossi, Larry Anderson, Peter Voorhees, Jack Khouri, Surbhi Sidana, Andrew Portuguese, Murali Janakiram, Hans Lee, Yi Lin, Ariel Grajales-Cruz, Krina Patel, Douglas Sborov
Journal: Blood
Blood (2025) 146 (Supplement 1): 823.
https://doi.org/10.1182/blood-2025-823
Published: 2025
Journal Articles

Impact of race and social deprivation on outcomes with modern day induction therapy in patients with newly diagnosed multiple myeloma: An ASH research collaborative data hub analysis

Free
Hamza Hashmi, Meera Mohan, Susan Geyer, Levi Pederson, Peyton Schumacher, Paul Gater, Shandra James, Emily Semmel, Travis Cleaves, Aaron Rosenberg, Samuel Rubinstein, Anita D'Souza, Joselle Cook, Mark Schroeder, Adam Sperling, Jeffrey Zonder, Ajay Nooka, Thomas Martin, Manisha Bhutani, Shambavi Richard, Saad Usmani
Journal: Blood
Blood (2025) 146 (Supplement 1): 2237.
https://doi.org/10.1182/blood-2025-2237
Published: 2025
Journal Articles

Outcomes of stem cell boost (SCB) versus supportive care alone for prolonged cytopenias after chimeric antigen receptor T cell therapy (CAR-T) in relapsed/refractory multiple myeloma (RRMM): A muli-center real-world analysis

Free
Cindy Varga, Myra Robinson, James Davis, Hamza Hashmi, Thomas Martin, Anupama Kumar, Douglas Sborov, Charlotte Wagner, Doris Hansen, Omar Alexis Castaneda Puglianini, Leyla Shune, Evguenia Bhurtel, Aimaz Afrough, Larry Anderson, Binod Dhakal, Megan Herr, Shambavi Richard, Alex Lieberman-Cribbin, Daniel Sherbenou, Peter Forsberg, Sneha Purvey, Jack Khouri, Yi Lin, Surbhi Sidana, Shonali Midha, Asad Haider, Krina Patel, Mehmet Kocoglu, Christopher Ferreri
Journal: Blood
Blood (2025) 146 (Supplement 1): 1035.
https://doi.org/10.1182/blood-2025-1035
Published: 2025
Journal Articles

Spatially resolved transcriptomics reveals immunosuppressive niches and clonal diversity in extramedullary disease in multiple myeloma refractory to immunotherapy

Free
Junia Vieira, Reyka Jayasinghe, Tarek Mouhieddine, Jordan Lu, Hajer Merarda, Darwin D'Souza, Hyo Jeong Nam, Adolfo Aleman, Meghana Ram, Zhihong Chen, Seunghee Kim-Schulze, Gaurav Bhatt, Julie Fortier, Michael Slade, Alina Dulau Florea, Rachel Brody, Larysa Sanchez, Cesar Rodriguez Valdes, Joshua Richter, Shambavi Richard, Adriana Rossi, Sundar Jagannath, Ravi Vij, Li Ding, Samir Parekh, Alessandro Lagana
Journal: Blood
Blood (2025) 146 (Supplement 1): 3949.
https://doi.org/10.1182/blood-2025-3949
Published: 2025
Journal Articles

Shared immune features correspond to high-risk multiple myeloma across multiple human subtypes and murine models

Free
Junia Vieira, Fnu Nabuqi, Alison Park, Alessia D'Anna, Tarek Mouhieddine, Kiana Chen, Erik Guillen, Roshan Mathews, Gregoire Lauvau, Jing Zhang, Katerina Kappes, Rudra Prasad Dutta, Julie Fortier, Chad Bjorklund, Michael Amatangelo, Anita Gandhi, Zhihong Chen, Seunghee Kim-Schulze, Michael Slade, Udo Oppermann, Rena Feinman, Santiago Thibaud, Joshua Richter, Shambavi Richard, Cesar Rodriguez Valdes, Adriana Rossi, Hearn Cho, Fotios Asimakopoulos, David Siegel, Ravi Vij, Sundar Jagannath, Samir Parekh, David Fooksman, Alessandro Lagana
Journal: Blood
Blood (2025) 146 (Supplement 1): 5723.
https://doi.org/10.1182/blood-2025-5723
Published: 2025
Journal Articles

Defining functional high-risk multiple myeloma in the era of modern induction therapy

Free
Barry Paul, Carlyn Tan, Susan Geyer, Levi Pederson, Peyton Schumacher, C. Kennedy, Emily Semmel, Shandra James, Travis Cleaves, Saurabh Zanwar, Mark Schroeder, Jeffrey Zonder, Thomas Martin, Ajay Nooka, Anita D'Souza, Shambavi Richard, Adam Sperling, Aaron Rosenberg, Samuel Rubinstein, Saad Usmani, Hamza Hashmi, Manisha Bhutani
Journal: Blood
Blood (2025) 146 (Supplement 1): 4014.
https://doi.org/10.1182/blood-2025-4014
Published: 2025
Journal Articles

Development of predictive relapse indicators for myeloma T cell engagers (PRIME) model for myeloma patients receiving BCMA- and GPRC5D-targeting T cell engagers

Free
Tarek Mouhieddine, Tianxiang Sheng, Junia Vieira, Adolfo Aleman, Zachary Avigan, Ariel Siegel, Mujahid Quidwai, Jordan Lu, Mohammad Rattu, Santiago Thibaud, Gurbakhash Kaur, Shambavi Richard, Adriana Rossi, Hearn Cho, Alessandro Lagana, Samantha Stclair, Dalia Abdel Azim, Larysa Sanchez, Joshua Richter, Cesar Rodriguez Valdes, Christian Salib, Erin Moshier, Samir Parekh, Sundar Jagannath
Journal: Blood
Blood (2025) 146 (Supplement 1): 3996.
https://doi.org/10.1182/blood-2025-3996
Published: 2025
Journal Articles

Safety and efficacy of AZD0120, a BCMA/CD19 dual-targeting CAR T-cell therapy, in relapsed/refractory multiple myeloma: Preliminary Results from the DURGA-1 Phase 1b/2 study

Free
Shambavi Richard, Mahmoud Gaballa, Tara Gregory, Saurabh Chhabra, Larry Anderson, Luciano Costa, Caitlin Costello, Scott Goldsmith, Doris Hansen, Sridevi Rajeeve, Shaji Kumar, Aravind Ramakrishnan, Minoo Battiwalla, Ajay Nooka, Hira Shaikh, Meiyue Grace Hong, Steven Wang, Patricia Cheung, Liang Li, Binod Dhakal
Journal: Blood
Blood (2025) 146 (Supplement 1): 269.
https://doi.org/10.1182/blood-2025-269
Published: 2025
Journal Articles

S100A8/A9 drives T cell exhaustion and compromises the therapeutic efficacy of bispecific antibodies in multiple myeloma.

Free
Adolfo Aleman, Oliver Van Oekelen, Shriya Desai, Sidorela Reci, Leah Grossman, Rudra Prasad Dutta, Mathieu Desaunay, Junia Vieira, Rongbao Zhao, Rahul Sanawar, Mani Mohindru, Tarek Mouhieddine, Alessandro Lagana, Marta Larrayoz, Poulikos Poulikakos, Gurbakhash Kaur, Larysa Sanchez, Cesar Rodriguez Valdes, Santiago Thibaud, Adriana Rossi, Shambavi Richard, Joshua Richter, Hearn Cho, Jose A. Martinez-Climent, Amit Verma, Sundar Jagannath, Samir Parekh
Journal: Blood
Blood (2025) 146 (Supplement 1): 916.
https://doi.org/10.1182/blood-2025-916
Published: 2025
Journal Articles

Impact of antibiotic timing on survival outcomes in CD19 and BCMA CAR-T cell therapy

Free
Serena Tharakan, Patrick Crorkin, Sana Ahmad, Jana Mihalyova, Shivani Handa, Jacques Azzi, Adriana Rossi, Shambavi Richard, Sundar Jagannath, Keren Osman, Alla Keyzner, Uroosa Ibrahim
Journal: Blood
Blood (2025) 146 (Supplement 1): 4113.
https://doi.org/10.1182/blood-2025-4113
Published: 2025
Journal Articles

Sequential targeting in multiple myeloma: talquetamab, a GPRC5D bispecific antibody, as a bridge to BCMA CAR-T therapy

Available to Purchase
Clinical Trials & Observations
Binod Dhakal, Othman S. Akhtar, David Fandrei, Alexandria Jensen, Rahul Banerjee, Darren Pan, Shambavi Richard, Reed Friend, Matthew Rees, Patrick Costello, Mariola Vazquez Martinez, Oren Pasvolsky, Charlotte Wagner, James A. Davis, Omar Castaneda Puglianini, Ran Reshef, Aimaz Afrough, Danai Dima, Manisha Bhutani, Omar Nadeem, Ricardo Parrondo, Ciara Freeman, Lekha Mikkilineni, Shahzad Raza, Larry D. Anderson Jr, Prashant Kapoor, Hitomi Hosoya, Saurabh Chhabra, Ariel Grajales-Cruz, Mahmoud Gaballa, Shonali Midha, Melissa Alsina, Douglas Sborov, Krina Patel, Yi Lin, Christopher Ferreri, Nico Gagelmann, Anupama Kumar, Doris Hansen, Andrew Cowan, Luciano J. Costa, Maximilian Merz, Surbhi Sidana
Journal: Blood
Blood (2025) 146 (17): 2063–2072.
https://doi.org/10.1182/blood.2025029773
Published: 2025
Includes: Supplemental data
Journal Articles

Racial and Ethnic Differences in Outcomes of Multiple Myeloma Patients Treated with Idecabtagene Vicleucel or Ciltacabtagene Autoleucel

Free
Lauren C. Peres, Alicia Richards, Surbhi Sidana, Laura B. Oswald, Danai Dima, Aimaz Afrough, Leyla O. Shune, Shonali Midha, Omar Castaneda, Christopher Ferreri, James A Davis, Oren Pasvolsky, Christen M. Dillard, Megan M Herr, Mehmet H. Kocoglu, Shebli Atrash, Brandon Blue, Evguenia Ouchveridze, Joseph P. McGuirk, Charlotte B Wagner, Radhika Bansal, Patrick Costello, Kinaya Smith, Alex Lieberman-Cribbin, Gabriel De Avila, Sneha Purvey, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Mahmoud R. Gaballa, Peter A. Forsberg, Ciara Louise Freeman, Murali Janakiram, Myo Htut, Sireesha Asoori, Nilesh Kalariya, Djordje Atanackovic, Binod Dhakal, Jack Khouri, Shahzad Raza, Ran Reshef, Melissa Alsina, Frederick L. Locke, Omar Nadeem, Faiz Anwer, Larry D Anderson, Jr., Shambavi Richard, Yi Lin, Thomas Martin, Peter M. Voorhees, Krina K. Patel, Doris K. Hansen, Douglas W Sborov
Journal: Blood
Blood (2024) 144 (Supplement 1): 3785.
https://doi.org/10.1182/blood-2024-210078
Published: 2024
Journal Articles

Idecabtagene Vicleucel (Ide-cel) in Patients (Pts) with Newly Diagnosed Multiple Myeloma (NDMM) with an Inadequate Response to Front-Line Autologous Stem Cell Transplantation (ASCT): KarMMa-2 Cohort 2c Extended Follow-up

Free
Barry Paul, Madhav V. Dhodapkar, Melissa Alsina, Jesús G. Berdeja, Shambavi Richard, Ravi Vij, Xavier Leleu, Daniel N. Egan, P. Leif Bergsagel, Ran Reshef, Saad Z. Usmani, Anna Truppel-Hartmann, Debashree Basudhar, Ethan G. Thompson, Fan Wu, Laurie Eliason, Soyun Park, Sinhan Tran, Maria Chaudhry, David S. Siegel, Krina K. Patel
Journal: Blood
Blood (2024) 144 (Supplement 1): 3388.
https://doi.org/10.1182/blood-2024-200829
Published: 2024
Journal Articles

Predictors and Characterization of Cytokine Release Syndrome (CRS) and Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) in Patients with Multiple Myeloma Receiving Teclistamab

Free
Oren Pasvolsky, Aimaz Afrough, Lei Feng, Wenli Dong, Tiffany Richards, James A Davis, Danai Dima, Ariel Grajales-Cruz, Mariola A Vazquez-Martinez, Aishwarya Sannareddy, Utkarsh Goel, Rahul Banerjee, Mahmoud R. Gaballa, Alex Lieberman-Cribbin, Masooma S Rana, Kelley Julian, Christopher J Ferreri, Leyla O. Shune, Shaun DeJarnette, Evguenia Ouchveridze, Sandra Susanibar-Adaniya, Andrew J. Portuguese, Peter A. Forsberg, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Adriana Rossi, Megan M Herr, Erin Eberwein, Chenyu Lin, Brandon Blue, Shahzad Raza, Yi Lin, Joseph P. McGuirk, Shebli Atrash, Douglas W Sborov, Peter M. Voorhees, Faiz Anwer, Doris K. Hansen, Krina K. Patel, Surbhi Sidana, Andrew J. Cowan, Larry D Anderson, Jr., Shambavi Richard, Alfred L. Garfall, Hans C. Lee, Jack Khouri
Journal: Blood
Blood (2024) 144 (Supplement 1): 3337.
https://doi.org/10.1182/blood-2024-206357
Published: 2024
Journal Articles

Initial Results of a Phase 1 First-in-Human Study of Cemsidomide (CFT7455), a Novel MonoDAC TM Degrader, with Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma

Free
Binod Dhakal, Andrew J. Yee, Paul G. Richardson, Sikander Ailawadhi, Saurabh Chhabra, Eli Muchtar, Jesús G. Berdeja, Shambavi Richard, Jeffrey V Matous, Urvi A. Shah, Mark A. Schroeder, Amro Ali, Leah Leahy, Riadh Lobbardi, Rong Chu, Eunju Hurh, Anthony S. Fiorino, Sagar Lonial
Journal: Blood
Blood (2024) 144 (Supplement 1): 3366.
https://doi.org/10.1182/blood-2024-204255
Published: 2024
Journal Articles

A Phase 2 Study of Daratumumab in Combination with Dose-Attenuated Bortezomib, Lenalidomide, and Dexamethasone in Transplant Ineligible Older Adults with Newly Diagnosed Multiple Myeloma

Free
Larysa J Sanchez, Erin Moshier, Alex Lieberman-Cribbin, Joshua Richter, Shambavi Richard, Adriana Rossi, Cesar Rodriguez, Santiago Thibaud, Hearn Jay Cho, Samir Parekh, Sundar Jagannath, Ajai Chari
Journal: Blood
Blood (2024) 144 (Supplement 1): 7043.
https://doi.org/10.1182/blood-2024-211704
Published: 2024
Journal Articles

Delayed Neutrophil Recovery Following BCMA-Directed CAR-T Correlates with Poor Outcomes and Is Associated with a Cytokine Signature of Persistent Inflammation and T Cell Checkpoint Activation

Free
Zachary M Avigan, Saoirse Bodnar, Darren Pan, Adolfo Aleman, Joshua Richter, Larysa J Sanchez, Cesar Rodriguez, Adriana Rossi, Shambavi Richard, Hearn Jay Cho, Sundar Jagannath, Samir Parekh, Santiago Thibaud
Journal: Blood
Blood (2024) 144 (Supplement 1): 3329.
https://doi.org/10.1182/blood-2024-202725
Published: 2024
Journal Articles

Post-CAR-T Driving Restrictions after Week 4 Appear Unnecessary: Data from the United States Myeloma Immunotherapy Consortium

Free
Rahul Banerjee, Alicia Richards, Jack Khouri, Murali Janakiram, Kara I. Cicero, Danai Dima, Mehmet H. Kocoglu, Leyla O. Shune, Evguenia Ouchveridze, Tania Jain, Aimaz Afrough, Saurabh Zanwar, Christopher Ferreri, Oren Pasvolsky, Lekha Mikkilineni, Sneha Purvey, Lauren C. Peres, Ciara Louise Freeman, Shonali Midha, Amer Beitinjaneh, James A Davis, Charlotte B Wagner, Megan M Herr, Peter A. Forsberg, Douglas W. Sborov, Shambavi Richard, Ran Reshef, Binod Dhakal, Veronika Bachanova, Joseph P. McGuirk, Peter M. Voorhees, Larry D Anderson, Jr., Yi Lin, Thomas G Martin, Surbhi Sidana, Krina K. Patel, Doris K. Hansen, Andrew J. Cowan, Gurbakhash Kaur
Journal: Blood
Blood (2024) 144 (Supplement 1): 3765.
https://doi.org/10.1182/blood-2024-199609
Published: 2024
Journal Articles

The Anti-BCMA Antibody-Drug Conjugate Hdp-101 with a Novel Amanitin Payload Shows Promising Initial First in Human Results in Relapsed Multiple Myeloma

Free
Robert Z. Orlowski, Shambavi Richard, Jonathan L. Kaufman, Sebastian Grosicki, Istvan Takacs, Andras Strassz, Andreas Martin Pahl, Michael Kulke, Thorsten Michael, Anette Last, Hajnalka Szaboki, Frank Richard, Oliver Schönborn-Kellenberger, Marc S. Raab
Journal: Blood
Blood (2024) 144 (Supplement 1): 3381.
https://doi.org/10.1182/blood-2024-210088
Published: 2024