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Shriya Desai
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Journal Articles

Genomic alterations in TET2 and EZH2 serve as critical drivers of clonal malignant evolution in anti-BCMA CAR-T therapy for multiple myeloma.

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Adolfo Aleman, Rudra Prasad Dutta, Oliver Van Oekelen, David Melnekoff, Tarek Mouhieddine, Leah Grossman, Sidorela Reci, Shriya Desai, Patrick Brunner, Alessandro Lagana, Sundar Jagannath, Joshua Brody, Samir Parekh
Journal: Blood
Blood (2025) 146 (Supplement 1): 3946.
https://doi.org/10.1182/blood-2025-3946
Published: 2025
Journal Articles

Epigenetic targeting of SETD8 in multiple myeloma

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Rudra Prasad Dutta, He Chen, Yue Zhong, Anqi Ma, Adolfo Aleman, Alison Park, Shriya Desai, Sidorela Reci, Ivan Odak, Ioanna Tsialta, Kedwin Ventura, H. Ümit Kaniskan, Alessandro Lagana, Jian Jin, Samir Parekh
Journal: Blood
Blood (2025) 146 (Supplement 1): 3310.
https://doi.org/10.1182/blood-2025-3310
Published: 2025
Journal Articles

S100A8/A9 drives T cell exhaustion and compromises the therapeutic efficacy of bispecific antibodies in multiple myeloma.

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Adolfo Aleman, Oliver Van Oekelen, Shriya Desai, Sidorela Reci, Leah Grossman, Rudra Prasad Dutta, Mathieu Desaunay, Junia Vieira, Rongbao Zhao, Rahul Sanawar, Mani Mohindru, Tarek Mouhieddine, Alessandro Lagana, Marta Larrayoz, Poulikos Poulikakos, Gurbakhash Kaur, Larysa Sanchez, Cesar Rodriguez Valdes, Santiago Thibaud, Adriana Rossi, Shambavi Richard, Joshua Richter, Hearn Cho, Jose A. Martinez-Climent, Amit Verma, Sundar Jagannath, Samir Parekh
Journal: Blood
Blood (2025) 146 (Supplement 1): 916.
https://doi.org/10.1182/blood-2025-916
Published: 2025
Journal Articles

BCMA CART Therapy Failure in Myeloma Is Associated with Immunosuppressive S100A8/9 Overexpression and Can be Ameliorated with Novel Monoclonal Antibodies

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Adolfo Aleman, Rongbao Zhao, Leah Grossman, Rahul Sanawar, Srinivas Aluri, Mani Mohindru, Rudra Prasad Dutta, Sidorela Reci, Junia Vieira, David Melnekoff, Alessandro Lagana, Shriya Desai, Sundar Jagannath, Amit Verma, Samir Parekh
Journal: Blood
Blood (2024) 144 (Supplement 1): 589.
https://doi.org/10.1182/blood-2024-201194
Published: 2024