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Journal Articles

An IFNγ-Mediated Immune Inflamed Microenvironment State in Multiple Myeloma with TP53 Loss That Can be Therapeutically Exploited

Blood (2024) 144 (Supplement 1): 670.

https://doi.org/10.1182/blood-2024-194041

Published: 2024

Journal Articles

Genomic and Single Cell Investigation of MRD Clonality in Genetically Engineered Mouse Models of Multiple Myeloma

Junfei Zhao, Marta Larrayoz, Chad C. Bjorklund, Anita K. Gandhi, Jose A. Martinez-Climent, Patrick R. Hagner, Maria Ortiz

Blood (2024) 144 (Supplement 1): 1409.

https://doi.org/10.1182/blood-2024-210958

Published: 2024

Journal Articles

Mapping Disease Transitions from Premalignant, Asymptomatic to Advanced Myeloma through Integrative Epigenomic and Transcriptional Analyses

Blood (2024) 144 (Supplement 1): 1889.

https://doi.org/10.1182/blood-2024-209833

Published: 2024

Journal Articles

Remodeling of the Immune Microenvironment By Oncogenic MYD88 Dictates Immunotherapy Responses across Indolent and Aggressive B-Cell Lymphomas

Jon Celay, Miriam Recalde, María Victoria Revuelta, Marta Larrayoz, Sara Rodriguez, Maria J Garcia-Barchino, Jennifer R. Chapman-Fredricks, Teresa Lozano, Juan J Lasarte, Ming Q. Du, Izidore S. Lossos, Sergio Roa, Aldo Roccaro, Miguel Canales, Felipe Prosper, Bruno Paiva, Leandro Cerchietti, Jose A. Martinez-Climent

Blood (2023) 142 (Supplement 1): 431.

https://doi.org/10.1182/blood-2023-173394

Published: 2023

Journal Articles

Spatial Transcriptomics Unveils Novel Potential Mechanisms of Disease in a MI cγ1 Multiple Myeloma in vivo Model

Blood (2023) 142 (Supplement 1): 4076.

https://doi.org/10.1182/blood-2023-181643

Published: 2023

Journal Articles

Comprehensive Characterization of the Bone Marrow Microenvironment Transcriptional Remodeling in the Progression from MGUS to Smoldering and Multiple Myeloma

Blood (2023) 142 (Supplement 1): 88.

https://doi.org/10.1182/blood-2023-178534

Published: 2023

Journal Articles

Immune Biomarkers of Survival and Severe Infection in Newly Diagnosed Multiple Myeloma (NDMM) Patients (pts) Treated with the Backbone Regimen Lenalidomide and Dexamethasone (Rd)

Catarina Maia, Noemi Puig, Cristina Pérez Ruiz, Maria Teresa Cedena Romero, Camila Guerrero, Marta Larrayoz, Cirino Botta, Norma C. Gutierrez, María José Calasanz, Maria Luisa Martin-Ramos, Miguel Hernández, Laura Rosinol Dachs, Esther González Garcia, Felipe De Arriba, Albert Oriol, Veronica Gonzalez-Calle, Fernando Escalante, Javier de la Rubia, Mercedes Gironella Mesa, Rafael Rios, Ricarda Belen Garcia Sanchez, Jose Maria Arguiñano PEREZ, Adrian Alegre, Jesus Martin, María del Carmen Couto Caro, Maria Casanova, Mario Arnao Herraiz, Ernesto Pérez, Sebastián Garzón López, Marta Sonia Gonzalez Perez, Guillermo Martín-Nuñez, Adriana Rossi, Morton Coleman, Cristina Encinas, Ana M. Vale, Ana Isabel Teruel, María Cortés Rodríguez, Jose A. Martinez-Climent, Juan-José Lahuerta, Joan Bladé Creixenti, Ruben Niesvizky, Jesús San-Miguel, Maria-Victoria Mateos, Bruno Paiva

Blood (2022) 140 (Supplement 1): 4200–4203.

https://doi.org/10.1182/blood-2022-163058

Published: 2022

Journal Articles

Waldenström's Macroglobulinemia (WM) Is Preceded By Clonal Lymphopoiesis Including MYD88 L265P in Progenitor B Cells

Blood (2020) 136 (Supplement 1): 42–43.

https://doi.org/10.1182/blood-2020-136982

Published: 2020

Journal Articles

Waldenström's Macroglobulinemia (WM) Is Preceded By Clonal Lymphopoiesis Including MYD88 L265P in Progenitor B Cells

Blood (2019) 134 (Supplement_1): 1527.

https://doi.org/10.1182/blood-2019-126889

Published: 2019

Journal Articles

Clinical Importance of DNA Methylation Signatures in Chronic Lymphocytic Leukaemia Patients Treated with Chemo-Immunotherapy

Blood (2017) 130 (Supplement 1): 56.

https://doi.org/10.1182/blood.V130.Suppl_1.56.56

Published: 2017

Journal Articles

The Contribution of Gene Mutations to Long-Term Clinical Outcomes: Data from the Randomised UK LRF CLL4 Trial

Blood (2017) 130 (Supplement 1): 259.

https://doi.org/10.1182/blood.V130.Suppl_1.259.259

Published: 2017

Journal Articles

Tailored Approaches for Refined Prognostication in Chronic Lymphocytic Leukemia Patients with Mutated Versus Unmutated Immunoglobulin Receptors

Blood (2016) 128 (22): 3199.

https://doi.org/10.1182/blood.V128.22.3199.3199

Published: 2016

Journal Articles

Surface IgM expression and function are associated with clinical behavior, genetic abnormalities, and DNA methylation in CLL

Annalisa D’Avola, Samantha Drennan, Ian Tracy, Isla Henderson, Laura Chiecchio, Marta Larrayoz, Matthew Rose-Zerilli, Jonathan Strefford, Christoph Plass, Peter W. Johnson, Andrew J. Steele, Graham Packham, Freda K. Stevenson, Christopher C. Oakes, Francesco Forconi

Blood (2016) 128 (6): 816–826.

https://doi.org/10.1182/blood-2016-03-707786

Published: 2016

Includes: Supplemental data

Journal Articles

IL-4 enhances expression and function of surface IgM in CLL cells

Maria M. Aguilar-Hernandez, Matthew D. Blunt, Rachel Dobson, Alison Yeomans, Stephen Thirdborough, Marta Larrayoz, Lindsay D. Smith, Adam Linley, Jonathan C. Strefford, Andrew Davies, Peter M. W. Johnson, Natalia Savelyeva, Mark S. Cragg, Francesco Forconi, Graham Packham, Freda K. Stevenson, Andrew J. Steele

Blood (2016) 127 (24): 3015–3025.

https://doi.org/10.1182/blood-2015-11-682906

Published: 2016

Includes: Supplemental data

Journal Articles

Genomic Disruption of the Histone Methyltransferase SETD2 in Chronic Lymphocytic Leukemia

Blood (2015) 126 (23): 365.

https://doi.org/10.1182/blood.V126.23.365.365

Published: 2015

Journal Articles

The Syk\Jak Inhibitor Cerdulatinib (PRT062070) Shows Promising Preclinical Activity in Chronic Lymphocytic Leukemia By Antagonising B Cell Receptor and Microenvironmental Signalling

Matthew D Blunt, PhD, Jack Parnell, BSc(hons), Marta Larrayoz, PhD, Lindsay Smith, PhD, Rachel Dobson, BSc(Hons), Jonathan C Strefford, PhD, Freda K Stevenson, DPhil, Francesco Forconi, MD DM, PhD FRCPath, Andrew J Davies, MRCP, Peter W Johnson, MD, Graham Packham, PhD, Greg P. Coffey, PhD, Mark S Cragg, PhD, Andrew J Steele, PhD

Blood (2015) 126 (23): 1716.

https://doi.org/10.1182/blood.V126.23.1716.1716

Published: 2015

Journal Articles

The PI3K/mTOR inhibitor PF-04691502 induces apoptosis and inhibits microenvironmental signaling in CLL and the Eµ-TCL1 mouse model

Matthew D. Blunt, Matthew J. Carter, Marta Larrayoz, Lindsay D. Smith, Maria Aguilar-Hernandez, Kerry L. Cox, Thomas Tipton, Mark Reynolds, Sarah Murphy, Elizabeth Lemm, Samantha Dias, Andrew Duncombe, Jonathan C. Strefford, Peter W. M. Johnson, Francesco Forconi, Freda K. Stevenson, Graham Packham, Mark S. Cragg, Andrew J. Steele

Blood (2015) 125 (26): 4032–4041.

https://doi.org/10.1182/blood-2014-11-610329

Published: 2015

Includes: Supplemental data

Journal Articles

Splicing Inhibition By Spliceostatin_A Is a Promising Therapeutic Strategy in Chronic Lymphocytic Leukaemia

Marta Larrayoz, PhD, Stuart Blakemore, Rachel Dobson, BSc, Matthew Rose-Zerilli, PhD, Renata Walewska, Matthew Blunt, PhD, Minoru Yoshida, PhD, David G Oscier, MD, Mark Cragg, PhD, Andrew J Steele, PhD, Jonathan C Strefford, PhD

Blood (2014) 124 (21): 3301.

https://doi.org/10.1182/blood.V124.21.3301.3301

Published: 2014

Journal Articles

The Dual PI3K/mTOR Inhibitor PF-04691502 Induces Substantial Apoptosis in Chronic Lymphocytic Leukemia Cells in Vitro and Prolongs Survival in the Eµ-TCL1 Mouse Model

Matthew D Blunt, PhD, Matthew J Carter, PhD, Marta Larrayoz, PhD, Maria Montserrat Aguilar, PhD, Sarah Murphy, Mark Reynolds, Thomas Tipton, Kerry Cox, Jonathan C Strefford, PhD, Freda K Stevenson, DPhil, Francesco Forconi, Graham Packham, PhD, Mark Cragg, PhD, Andrew J Steele, PhD

Blood (2014) 124 (21): 832.

https://doi.org/10.1182/blood.V124.21.832.832

Published: 2014

Journal Articles

Surface IgM Levels Independently Influence Clinical Behavior and Associate with Altered Phenotype and Genetics in Chronic Lymphocytic Leukemia

Samantha J Drennan, PhD, Annalisa D'Avola, MSc, Ian Tracy, Isla Henderson, Marta Larrayoz, PhD, Carina Mundy, Andrew S. Duncombe, MD, Andrew J. Davies, MD PhD, Davide Rossi, MD PhD, Fiona M Ross, DPhil, Laura Chiecchio, PhD, Kathleen N. Potter, PhD, Jonathan Strefford, PhD, Andrew J Steele, PhD, Peter W Johnson, MD, Graham Packham, PhD, Freda K Stevenson, DPhil, Francesco Forconi, MD DM, PhD FRCPath

Blood (2014) 124 (21): 830.

https://doi.org/10.1182/blood.V124.21.830.830

Published: 2014

NARROW

An IFNγ-Mediated Immune Inflamed Microenvironment State in Multiple Myeloma with TP53 Loss That Can be Therapeutically Exploited

Genomic and Single Cell Investigation of MRD Clonality in Genetically Engineered Mouse Models of Multiple Myeloma

Mapping Disease Transitions from Premalignant, Asymptomatic to Advanced Myeloma through Integrative Epigenomic and Transcriptional Analyses

Remodeling of the Immune Microenvironment By Oncogenic MYD88 Dictates Immunotherapy Responses across Indolent and Aggressive B-Cell Lymphomas

Spatial Transcriptomics Unveils Novel Potential Mechanisms of Disease in a MI cγ1 Multiple Myeloma in vivo Model

Comprehensive Characterization of the Bone Marrow Microenvironment Transcriptional Remodeling in the Progression from MGUS to Smoldering and Multiple Myeloma

Immune Biomarkers of Survival and Severe Infection in Newly Diagnosed Multiple Myeloma (NDMM) Patients (pts) Treated with the Backbone Regimen Lenalidomide and Dexamethasone (Rd)

Waldenström's Macroglobulinemia (WM) Is Preceded By Clonal Lymphopoiesis Including MYD88 L265P in Progenitor B Cells

Waldenström's Macroglobulinemia (WM) Is Preceded By Clonal Lymphopoiesis Including MYD88 L265P in Progenitor B Cells

Clinical Importance of DNA Methylation Signatures in Chronic Lymphocytic Leukaemia Patients Treated with Chemo-Immunotherapy

The Contribution of Gene Mutations to Long-Term Clinical Outcomes: Data from the Randomised UK LRF CLL4 Trial

Tailored Approaches for Refined Prognostication in Chronic Lymphocytic Leukemia Patients with Mutated Versus Unmutated Immunoglobulin Receptors

Surface IgM expression and function are associated with clinical behavior, genetic abnormalities, and DNA methylation in CLL

IL-4 enhances expression and function of surface IgM in CLL cells

Genomic Disruption of the Histone Methyltransferase SETD2 in Chronic Lymphocytic Leukemia

The Syk\Jak Inhibitor Cerdulatinib (PRT062070) Shows Promising Preclinical Activity in Chronic Lymphocytic Leukemia By Antagonising B Cell Receptor and Microenvironmental Signalling

The PI3K/mTOR inhibitor PF-04691502 induces apoptosis and inhibits microenvironmental signaling in CLL and the Eµ-TCL1 mouse model

Splicing Inhibition By Spliceostatin_A Is a Promising Therapeutic Strategy in Chronic Lymphocytic Leukaemia

The Dual PI3K/mTOR Inhibitor PF-04691502 Induces Substantial Apoptosis in Chronic Lymphocytic Leukemia Cells in Vitro and Prolongs Survival in the Eµ-TCL1 Mouse Model

Surface IgM Levels Independently Influence Clinical Behavior and Associate with Altered Phenotype and Genetics in Chronic Lymphocytic Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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