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Paula Aguirre-Ruiz
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Journal Articles

Mapping Disease Transitions from Premalignant, Asymptomatic to Advanced Myeloma through Integrative Epigenomic and Transcriptional Analyses

Aleksandra Kurowska, Azari Bantan, Raghad Shuwaikan, Itziar Cenzano, Paula Aguirre-Ruiz, Estíbaliz Miranda, Leire Garate, Amaia Vilas-Zornoza, Patxi San-Martin, Marta Larrayoz, Nahia Gómez-Echarte, Beñat Ariceta, Daniel Soto Ortiz, Turki Sobahy, José Ignacio Martín-Subero, Vincenzo Lagani, Jesper Tegnér, Jose A. Martinez-Climent, Xabier Agirre, Mikel Hernáez Arrazola, Felipe Prosper, David Gomez-Cabrero
Journal: Blood
Blood (2024) 144 (Supplement 1): 1889.
https://doi.org/10.1182/blood-2024-209833
Published: 2024
Journal Articles

Multiomic Characterization of Clonotypic B Cells in Patients with Monoclonal Gammopathies

Carmen Gonzalez, Camila Guerrero, Juan-José Garcés, Alejandro Medina, Noemi Puig, Maria Teresa Cedena Romero, Diego Alignani, Sarai Sarvide, Paula Aguirre-Ruiz, Jose Maria Lamo-Espinosa, Felipe Prosper, Paula Rodríguez-Otero, Jose A. Martinez-Climent, Aldo Roccaro, Antonio Sacco, Mario Nuvolone, Giovanni O. Palladini, Laura Rosiñol Dachs, Ramon García-Sanz, Joaquín Martínez-Lopez, Juan-Jose Lahuerta Palacios, Maria-Victoria Mateos, Joan Bladé, Jesús F. San-Miguel, Bruno Paiva
Journal: Blood
Blood (2024) 144 (Supplement 1): 1879.
https://doi.org/10.1182/blood-2024-201435
Published: 2024
Journal Articles

Combined Single-Cell and Spatial Transcriptomics Unveil the Complex Organization of the Non-Immune Human Bone Marrow Microenvironment during Aging

Itziar Cenzano, Miguel Cocera, Robert Lehmann, Jin Ye, Amaia Vilas-Zornoza, Patxi San-Martin, Paula Aguirre-Ruiz, Diego Alignani, Aitziber Lopez, Bruno Paiva, Marta Miñana Barrios, Ignacio Sancho Gonzalez, Javier Ruiz, Sarai Sarvide, Purificacion Ripalda-Cemborain, Laura Sudupe, Emma Muiños-Lopez, Vincenzo Lagani, Jesper Tegner, Borja Saez-Ochoa, Isabel A Calvo, David Gomez-Cabrero, Felipe Prosper
Journal: Blood
Blood (2023) 142 (Supplement 1): 2706.
https://doi.org/10.1182/blood-2023-179730
Published: 2023
Journal Articles

The Transcriptional Impact of 5q Deletion in MDS at Single Cell Resolution

Aintzane Diaz-Mazkiaran, Guillermo Serrano, Nerea Berastegui, Paula Garcia-Olloqui, Sofia Huerga, Ana Alfonso Pierola, Asier Ullate-Agote, Beñat Ariceta, Marina Ainciburu, Amaia Vilas-Zornoza, Patxi San-Martin, Paula Aguirre-Ruiz, Jose Maria Lamo De Espinosa, Pamela Acha, Oriol Calvete, Tamara Jimenez, Antonieta Molero, Julia Montoro, Maria Diez-Campelo, David Valcarcel, Francesc Sole, Idoia Ochoa, Teresa Ezponda, Felipe Prosper, Mikel Hernaez
Journal: Blood
Blood (2023) 142 (Supplement 1): 1850.
https://doi.org/10.1182/blood-2023-186173
Published: 2023
Journal Articles

Spatial Transcriptomics Unveils Novel Potential Mechanisms of Disease in a MI cγ1 Multiple Myeloma in vivo Model

Laura Sudupe, Emma Muiños-Lopez, Isabel A Calvo, Ana Rosa Lopez-Perez, Amaia Vilas-Zornoza, Sarai Sarvide, Purificacion Ripalda-Cemborain, Azari Bantan, Jin Ye, Vincenzo Lagani, Paula Aguirre-Ruiz, Patxi San-Martin, Itziar Cenzano, Marta Larrayoz, Laura Alvarez-Gigli, Marta Abengozar-Muela, Borja Saez-Ochoa, Phillip T Newton, Jesper Tegner, Bruno Paiva, Jose A. A Martinez-Climent, David Gomez-Cabrero, Felipe Prosper
Journal: Blood
Blood (2023) 142 (Supplement 1): 4076.
https://doi.org/10.1182/blood-2023-181643
Published: 2023
Journal Articles

Light Chain Amyloidosis Plasma Cells Show Specific Chromatin Accessibility and Transcriptome

Beñat Ariceta, Alice Nevone, Itziar Cenzano, Ane Amundarain, Amaia Vilas-Zornoza, Leire Garate, Paula Aguirre-Ruiz, Estibaliz Miranda, Patxi San-Martin, Paolo Milani, Ramon Lecumberri Villamediana, Diego Alignani, Giovanni Palladini, Bruno Paiva, Jose Ignacio Martin-Subero, Giampaolo Merlini, Jesus San-Miguel, Mikel Hernaez, David Gomez-Cabrero, Xabier Agirre, Mario Nuvolone, Felipe Prosper
Journal: Blood
Blood (2023) 142 (Supplement 1): 4676.
https://doi.org/10.1182/blood-2023-185614
Published: 2023
Journal Articles

A Multi-Omic Study Unveils a Clonal Population of TET2-Mutated Infiltrating T-Cells in Germinal Center B Cell Lymphomas (DLBCL and FL)

Sofia Huerga, Beñat Ariceta, Paula Aguirre-Ruiz, Patxi San-Martin, Sarai Sarvide, Marta Abengozar-Muela, Diego Alignani, Rocio Figueroa, Carlos Grande, Alvaro Lopez-Janeiro, Emma Muiños-Lopez, Juan Roberto Rodriguez-Madoz, Amaia Vilas-Zornoza, Felipe Prosper, Miguel Canales
Journal: Blood
Blood (2023) 142 (Supplement 1): 3003.
https://doi.org/10.1182/blood-2023-182830
Published: 2023
Journal Articles

Comprehensive Characterization of the Bone Marrow Microenvironment Transcriptional Remodeling in the Progression from MGUS to Smoldering and Multiple Myeloma

Itziar Cenzano, Miguel Cocera, Azari Bantan, Marta Larrayoz, Amaia Vilas-Zornoza, Patxi San-Martin, Paula Aguirre-Ruiz, Beñat Ariceta, Jin Ye, Diego Alignani, Aitziber Lopez, Aleksandra Kurowska, Fatimah AlSultan, Raghad Shuwaikan, Vincenzo Lagani, Jesper Tegner, Iñaki I. Martin Subero, Jose A. A Martinez-Climent, Xabier Agirre, Borja Saez-Ochoa, Bruno Paiva, Jesus San-Miguel, Mikel Hernaez, Isabel A Calvo, David Gomez-Cabrero, Felipe Prosper
Journal: Blood
Blood (2023) 142 (Supplement 1): 88.
https://doi.org/10.1182/blood-2023-178534
Published: 2023
Journal Articles

Minimal Residual Disease Detection By Single Cell DNA Sequencing Technology: A Feasible Approach for Clinical Application and Identification of the Landscape of MRD Clones

Ana Alfonso Pierola, Beñat Ariceta, Amaia Vilas-Zornoza, Paula Aguirre-Ruiz, Sarai Sarvide, Patxi San-Martin, Maria-Antonia Fortuño, Catia Simoes, Leire Burgos, Maria Jose Larrayoz, Carmen Chillon, Olga Arce, Teresa Bernal Del Castillo, Mercedes Colorado, Laida Cuevas Palomares, Inmaculada Marchante, Maria Carmen Mateos, Mayte Olave, Jose A. Pérez-Simón, Maria Jose Calasanz, Ramon Garcia-Sanz, Bruno Paiva, Pau Montesinos, Felipe Prosper
Journal: Blood
Blood (2023) 142 (Supplement 1): 2958.
https://doi.org/10.1182/blood-2023-188865
Published: 2023