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Journal Articles

A Phase 2 Study of Daratumumab in Combination with Dose-Attenuated Bortezomib, Lenalidomide, and Dexamethasone in Transplant Ineligible Older Adults with Newly Diagnosed Multiple Myeloma

Larysa J Sanchez, Erin Moshier, Alex Lieberman-Cribbin, Joshua Richter, Shambavi Richard, Adriana Rossi, Cesar Rodriguez, Santiago Thibaud, Hearn Jay Cho, Samir Parekh, Sundar Jagannath, Ajai Chari
Journal: Blood
Blood (2024) 144 (Supplement 1): 7043.
https://doi.org/10.1182/blood-2024-211704
Published: 2024
Journal Articles

Combined PD-1 and Tim-3 Blockade Improves the in Vitro Anti-Myeloma Activity of T Cells of Patients on Talquetamab

Tarek H. Mouhieddine, Junia Vieira, Adolfo Aleman, Leah Grossman, David Melnekoff, Bhaskar Upadhyaya, Samantha St. Clair, Monica Garcia-Barros, Meghana Ram, Santiago Thibaud, Adriana Rossi, Shambavi Richard, Cesar Rodriguez, Joshua Richter, Hearn Jay Cho, Larysa Sanchez, Sundar Jagannath, Ajai Chari, Rachel Brody, Christian Salib, Alessandro Lagana, Samir Parekh
Journal: Blood
Blood (2024) 144 (Supplement 1): 357.
https://doi.org/10.1182/blood-2024-204929
Published: 2024
Journal Articles

BMS-986393, a G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D)-Targeted CAR T Cell Therapy, in Patients (pts) with Relapsed/Refractory (RR) Multiple Myeloma (MM) and 1-3 Prior Regimens: Updated Phase 1 Safety and Efficacy Results

Susan Bal, Myo Htut, Jesús G. Berdeja, Larry D Anderson, Jr., Adriana Rossi, Tara Gregory, Thomas G Martin, Luciano J. Costa, Hongxiang Hu, Jinjie Chen, Chaoqun Mei, Naomey Sarkis, Alok Shrestha, Safiyyah Ziyad, Wei-Ming Kao, Allison J Kaeding, Michael R. Burgess, Omar Nadeem
Journal: Blood
Blood (2024) 144 (Supplement 1): 2069.
https://doi.org/10.1182/blood-2024-203279
Published: 2024
Journal Articles

Outcomes of Teclistamab (Tec) in Patients with Relapsed/Refractory Multiple Myeloma (RRMM) with Prior Exposure to BCMA-Directed Therapy (BCMA-DT): A Multicenter Study from the U.S. Multiple Myeloma Immunotherapy Consortium

Danai Dima, Mariola A Vazquez-Martinez, James A Davis, Utkarsh Goel, Aimaz Afrough, Aishwarya Sannareddy, Oren Pasvolsky, Beatrice Razzo, Rahul Banerjee, Jack Khouri, Ariel Grajales-Cruz, Alex Lieberman-Cribbin, Masooma Shifa Rana, Kelley Julian, Shaun DeJarnette, Andrew J Portuguese, Mahmoud R. Gaballa, Gabriel De Avila, Sandra Susanibar-Adaniya, Shahzad Raza, Megan M Herr, Evguenia Ouchveridze, Tiffany Richards, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Daniel Schrum, Omar Castaneda, Adriana Rossi, Chenyu Lin, Peter A. Forsberg, Yi Lin, Shebli Atrash, Douglas W Sborov, Kenneth H. Shain, Peter M. Voorhees, Shambavi Richard, Alfred L. Garfall, Doris K. Hansen, Surbhi Sidana, Krina K. Patel, Andrew J. Cowan, Larry D Anderson, Jr., Hans C. Lee, Faiz Anwer, Christopher Ferreri, Leyla O. Shune
Journal: Blood
Blood (2024) 144 (Supplement 1): 897.
https://doi.org/10.1182/blood-2024-203409
Published: 2024
Journal Articles

Efficacy and Safety with Extended Follow-up in a Phase 1 Study of BMS-986393, a G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D)-Targeted CAR T Cell Therapy, in Patients (pts) with Heavily Pretreated Relapsed/Refractory (RR) Multiple Myeloma (MM)

Susan Bal, Larry D Anderson, Jr., Omar Nadeem, Jesús G. Berdeja, Adriana Rossi, Tara Gregory, Mehmet Hakan Koçoğlu, Thomas G Martin, Daniel N. Egan, Luciano J. Costa, Hongxiang Hu, Jinjie Chen, Chaoqun Mei, Naomey Sarkis, Alok Shrestha, Safiyyah Ziyad, Wei-Ming Kao, Allison J Kaeding, Michael R. Burgess, Myo Htut
Journal: Blood
Blood (2024) 144 (Supplement 1): 922.
https://doi.org/10.1182/blood-2024-201356
Published: 2024
Journal Articles

Outcomes of Elderly Patients with Relapsed Refractory Multiple Myeloma (RRMM) Treated with Teclistamab: A Multicenter Study from the U.S. Multiple Myeloma Immunotherapy Consortium

Oren Pasvolsky, Danai Dima, Lei Feng, Wenli Dong, Tiffany Richards, James A Davis, Aimaz Afrough, Mariola A Vazquez-Martinez, Aishwarya Sannareddy, Utkarsh Goel, Rahul Banerjee, Jack Khouri, Frances N. Cervoni Curet, Mahmoud R. Gaballa, Alex Lieberman-Cribbin, Masooma S Rana, Kelley Julian, Christopher J Ferreri, Leyla O. Shune, Shaun DeJarnette, Evguenia Ouchveridze, Sandra Susanibar-Adaniya, Andrew J. Portuguese, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Adriana Rossi, Megan M Herr, Daniel Schrum, Chenyu Lin, Shahzad Raza, Yi Lin, Shebli Atrash, Joseph P. McGuirk, Douglas W Sborov, Peter M. Voorhees, Faiz Anwer, Melissa Alsina, Ciara Louise Freeman, Alfred L. Garfall, Surbhi Sidana, Andrew J. Cowan, Larry D Anderson, Jr., Doris K. Hansen, Shambavi Richard, Krina K. Patel, Hans C. Lee, Ariel Grajales-Cruz
Journal: Blood
Blood (2024) 144 (Supplement 1): 934.
https://doi.org/10.1182/blood-2024-205989
Published: 2024
Journal Articles

Delayed Neutrophil Recovery Following BCMA-Directed CAR-T Correlates with Poor Outcomes and Is Associated with a Cytokine Signature of Persistent Inflammation and T Cell Checkpoint Activation

Zachary M Avigan, Saoirse Bodnar, Darren Pan, Adolfo Aleman, Joshua Richter, Larysa J Sanchez, Cesar Rodriguez, Adriana Rossi, Shambavi Richard, Hearn Jay Cho, Sundar Jagannath, Samir Parekh, Santiago Thibaud
Journal: Blood
Blood (2024) 144 (Supplement 1): 3329.
https://doi.org/10.1182/blood-2024-202725
Published: 2024
Journal Articles

Enhanced Detection of Pathogenic Germline Variants in Plasma Cell Disorders: Impact of a Targeted Genetic Counseling Referral Pathway

Saoirse Bodnar, Tehilla Brander, Zachary M Avigan, William Genthe, David Melnekoff, Alessandro Lagana, Jane Houldsworth, Shambavi Richard, Joshua Richter, Larysa J Sanchez, Cesar Rodriguez, Adriana Rossi, Hearn Jay Cho, Kenan Onel, Sundar Jagannath, Manisha Balwani, Samir Parekh, Santiago Thibaud
Journal: Blood
Blood (2024) 144 (Supplement 1): 1970.
https://doi.org/10.1182/blood-2024-212204
Published: 2024
Journal Articles

Predictors and Characterization of Cytokine Release Syndrome (CRS) and Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) in Patients with Multiple Myeloma Receiving Teclistamab

Oren Pasvolsky, Aimaz Afrough, Lei Feng, Wenli Dong, Tiffany Richards, James A Davis, Danai Dima, Ariel Grajales-Cruz, Mariola A Vazquez-Martinez, Aishwarya Sannareddy, Utkarsh Goel, Rahul Banerjee, Mahmoud R. Gaballa, Alex Lieberman-Cribbin, Masooma S Rana, Kelley Julian, Christopher J Ferreri, Leyla O. Shune, Shaun DeJarnette, Evguenia Ouchveridze, Sandra Susanibar-Adaniya, Andrew J. Portuguese, Peter A. Forsberg, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Adriana Rossi, Megan M Herr, Erin Eberwein, Chenyu Lin, Brandon Blue, Shahzad Raza, Yi Lin, Joseph P. McGuirk, Shebli Atrash, Douglas W Sborov, Peter M. Voorhees, Faiz Anwer, Doris K. Hansen, Krina K. Patel, Surbhi Sidana, Andrew J. Cowan, Larry D Anderson, Jr., Shambavi Richard, Alfred L. Garfall, Hans C. Lee, Jack Khouri
Journal: Blood
Blood (2024) 144 (Supplement 1): 3337.
https://doi.org/10.1182/blood-2024-206357
Published: 2024
Journal Articles

Interventions and outcomes of patients with multiple myeloma receiving salvage therapy after BCMA-directed CAR T therapy

Clinical Trials & Observations
Oliver Van Oekelen, Karthik Nath, Tarek H. Mouhieddine, Tasmin Farzana, Adolfo Aleman, David T. Melnekoff, Yogita Ghodke-Puranik, Gunjan L. Shah, Alexander Lesokhin, Sergio Giralt, Santiago Thibaud, Adriana Rossi, Cesar Rodriguez, Larysa Sanchez, Joshua Richter, Shambavi Richard, Hearn J. Cho, Ajai Chari, Saad Z. Usmani, Sundar Jagannath, Urvi A. Shah, Sham Mailankody, Samir Parekh
Journal: Blood
Blood (2023) 141 (7): 756–765.
https://doi.org/10.1182/blood.2022017848
Published: 2023
Includes: Supplemental data
Journal Articles

Gain of chr1q Portends Poor Outcomes in Multiple Myeloma Patients Treated with Venetoclax

Alessandro Lagana, Santiago Thibaud, David T. Melnekoff, Paula Restrepo, Violetta Leshchenko, Jonathan McCafferty, Scott Newman, Abbi Kern, David Corrigan, Feras Hantash, Adriana Rossi, Cesar Rodriguez, Larysa Sanchez, Shambavi Richard, Ajai Chari, Hearn J. Cho, Sundar Jagannath, Joshua Richter, Samir Parekh
Journal: Blood
Blood (2022) 140 (Supplement 1): 4388–4390.
https://doi.org/10.1182/blood-2022-166572
Published: 2022
Journal Articles

Immune Recovery Post BCMA CAR-T: Implications for Infection Prophylaxis and Vaccinations

Shambavi Richard, Guido Lancman, Santiago Thibaud, Ajai Chari, Samir Parekh, Adriana Rossi, Hearn J. Cho, Larysa Sanchez, Joshua Richter, Cesar Rodriguez, Elizabeth Aronson, Karen Louw, Kiah Purcell, Daniel Verina, Juliet Escalon, Sundar Jagannath
Journal: Blood
Blood (2022) 140 (Supplement 1): 7444–7446.
https://doi.org/10.1182/blood-2022-170404
Published: 2022
Journal Articles

Timing and Nature of Infections in Multiple Myeloma Patients Treated with Anti-BCMA CAR-T Cells

Guido Lancman, Margaret Shyu, Megan Metzger, Kian Parsa, Hearn J. Cho, Samir Parekh, Joshua Richter, Cesar Rodriguez, Adriana Rossi, Larysa Sanchez, Santiago Thibaud, Sundar Jagannath, Ajai Chari, Shambavi Richard
Journal: Blood
Blood (2022) 140 (Supplement 1): 7198–7199.
https://doi.org/10.1182/blood-2022-163757
Published: 2022
Journal Articles

Immune Biomarkers of Survival and Severe Infection in Newly Diagnosed Multiple Myeloma (NDMM) Patients (pts) Treated with the Backbone Regimen Lenalidomide and Dexamethasone (Rd)

Catarina Maia, Noemi Puig, Cristina Pérez Ruiz, Maria Teresa Cedena Romero, Camila Guerrero, Marta Larrayoz, Cirino Botta, Norma C. Gutierrez, María José Calasanz, Maria Luisa Martin-Ramos, Miguel Hernández, Laura Rosinol Dachs, Esther González Garcia, Felipe De Arriba, Albert Oriol, Veronica Gonzalez-Calle, Fernando Escalante, Javier de la Rubia, Mercedes Gironella Mesa, Rafael Rios, Ricarda Belen Garcia Sanchez, Jose Maria Arguiñano PEREZ, Adrian Alegre, Jesus Martin, María del Carmen Couto Caro, Maria Casanova, Mario Arnao Herraiz, Ernesto Pérez, Sebastián Garzón López, Marta Sonia Gonzalez Perez, Guillermo Martín-Nuñez, Adriana Rossi, Morton Coleman, Cristina Encinas, Ana M. Vale, Ana Isabel Teruel, María Cortés Rodríguez, Jose A. Martinez-Climent, Juan-José Lahuerta, Joan Bladé Creixenti, Ruben Niesvizky, Jesús San-Miguel, Maria-Victoria Mateos, Bruno Paiva
Journal: Blood
Blood (2022) 140 (Supplement 1): 4200–4203.
https://doi.org/10.1182/blood-2022-163058
Published: 2022
Journal Articles

Salvage with Sequential T Cell Redirection for Myeloma Patients Who Have Previously Progressed on T Cell Directed Therapy Is Associated with Significant Cellular Activation of the Immune Microenvironment

Adolfo Aleman, Ariel Kogan Zajdman, Yogita Ghodke-Puranik, Bhaskar Upadhyaya, Tarek H. Mouhieddine, Oliver Van Oekelen, Larysa Sanchez, Shambavi Richard, Adriana Rossi, Joshua Richter, Hearn J. Cho, Cesar Rodriguez, Ajai Chari, Sundar Jagannath, Samir Parekh
Journal: Blood
Blood (2022) 140 (Supplement 1): 4193–4195.
https://doi.org/10.1182/blood-2022-169538
Published: 2022
Journal Articles

Infections and Severe Hypogammaglobulinemia in Multiple Myeloma Patients Treated with Anti-BCMA Bispecific Antibodies

Guido Lancman, Kian Parsa, Cesar Rodriguez, Joshua Richter, Hearn J. Cho, Samir Parekh, Shambavi Richard, Adriana Rossi, Larysa Sanchez, Santiago Thibaud, Sundar Jagannath, Ajai Chari
Journal: Blood
Blood (2022) 140 (Supplement 1): 10073–10074.
https://doi.org/10.1182/blood-2022-163733
Published: 2022
Journal Articles

Extramedullary Relapse Post CAR-T

Shambavi Richard, Guido Lancman, Adriana Rossi, Ajai Chari, Samir Parekh, Larysa Sanchez, Cesar Rodriguez, Hearn J. Cho, Joshua Richter, Santiago Thibaud, Kiah Purcell, Elizabeth Aronson, Daniel Verina, Juliet Escalon, Karen Louw, Sundar Jagannath
Journal: Blood
Blood (2022) 140 (Supplement 1): 4301–4302.
https://doi.org/10.1182/blood-2022-170119
Published: 2022
Journal Articles

Universal Updated Phase 1 Data Highlights Role of Allogeneic Anti-BCMA ALLO-715 Therapy for Relapsed/Refractory Multiple Myeloma

Sham Mailankody, Jeffrey V. Matous, Michaela Liedtke, Surbhi Sidana, Olalekan O. Oluwole, Meera Mohan, Jose C. Cruz, Rajneesh Nath, Faiz Anwer, Adriana Rossi, Myo Htut, Shahbaz A. Malik, Srinivas Ghatta, Myles Dillon, Wendy Ying, Lynn Navale, Erin E. Karski, Arun Balakumaran, Shaji K. Kumar
Journal: Blood
Blood (2022) 140 (Supplement 1): 4620–4622.
https://doi.org/10.1182/blood-2022-158231
Published: 2022
Journal Articles

Comprehensive Characterization of Prolonged Unexplained Cytopenias in Relapsed/Refractory Multiple Myeloma Patients Following BCMA-Directed CAR-T Cell Therapy

Santiago Thibaud, Md. Babu Mia, Oliver Van Oekelen, Tarek H. Mouhieddine, Christoph Schaniel, Yogita Ghodke-Puranik, Adolfo Aleman, Bhaskar Upadhyaya, Guido Lancman, Alessandro Lagana, Shambavi Richard, Adriana Rossi, Ajai Chari, Larysa Sanchez, Cesar Rodriguez, Hearn J. Cho, Joshua Richter, Ronald Hoffman, Sundar Jagannath, Samir Parekh
Journal: Blood
Blood (2022) 140 (Supplement 1): 614–616.
https://doi.org/10.1182/blood-2022-165646
Published: 2022
Journal Articles

BiRd (clarithromycin, lenalidomide, dexamethasone): an update on long-term lenalidomide therapy in previously untreated patients with multiple myeloma

Brief Report
Adriana Rossi, Tomer Mark, David Jayabalan, Paul Christos, Faiza Zafar, Karen Pekle, Roger Pearse, Selina Chen-Kiang, Morton Coleman, Ruben Niesvizky
Journal: Blood
Blood (2013) 121 (11): 1982–1985.
https://doi.org/10.1182/blood-2012-08-448563
Published: 2013
Includes: Supplemental data