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Journal Articles

Talquetamab plus daratumumab for the treatment of relapsed or refractory multiple myeloma in the TRIMM-2 study

Available to Purchase
Clinical Trials & Observations
Ajai Chari, Niels W. C. J. van de Donk, Bhagirathbhai Dholaria, Katja Weisel, María-Victoria Mateos, Hartmut Goldschmidt, Thomas G. Martin, Daniel Morillo, Donna Reece, Paula Rodríguez-Otero, Manisha Bhutani, Anita D’Souza, Albert Oriol, Laura Rosiñol, Nizar J. Bahlis, Deeksha Vishwamitra, Sheri Skerget, Raluca I. Verona, Kalpana Bakshi, Lijuan Kang, Thomas J. Prior, Lien Vandenberk, Jaszianne Tolbert, Sangmin Lee, M. Damiette Smit, Ralph Wäsch
Journal: Blood
Blood (2025) 146 (24): 2902–2913.
https://doi.org/10.1182/blood.2025029360
Published: 2025
Includes: Supplemental data
Journal Articles

Impact of short-form, case-based continuing medical education on community clinicians' knowledge and competence in optimizing bispecific antibody therapy for Relapsed/Refractory multiple myeloma

Free
Meghan Coulehan, Aisha Suhail, Emily Kitterman, Ajai Chari, Jesús Berdeja
Journal: Blood
Blood (2025) 146 (Supplement 1): 4646.
https://doi.org/10.1182/blood-2025-4646
Published: 2025
Journal Articles

Utility and sensitivity of wett-SA53 to measure dysgeusia associated with talquetamab, a GPRC5D×CD3 bispecific antibody, in Relapsed/Refractory multiple myeloma: Preliminary data from the talisman study

Free
Rakesh Popat, Niels W.C.J. van de Donk, Beth Faiman, Junichiro Yuda, Kihyun Kim, Abel Costa, Alexa Laheij, Richard Doty, James Omel, Brea Lipe, Larysa Sanchez, Ajai Chari, Alexander Lin, Hervé Sroussi, Mariana Fernandez, Katy Gray, Gloria Aguilar, Kasey Bolyard, Jennifer Schultz, Keqin Qi, Diana Cortes-Selva, Jing Zhang, Christoph Heuck, Kelly Hawks, Ken Tian, Monique Franca, Leo Rasche
Journal: Blood
Blood (2025) 146 (Supplement 1): 5821.
https://doi.org/10.1182/blood-2025-5821
Published: 2025
Journal Articles

Measurable residual disease in newly diagnosed multiple myeloma: Experience from a large cohort from an academic medical center

Free
Alberto Blanco, Andrés Arroyo, Ajai Chari, Thomas Martin, Shagun Arora, Alfred Chung, Anupama Kumar, Nina Shah, Joaquin Martinez-Lopez, Jeffrey Lee Wolf
Journal: Blood
Blood (2025) 146 (Supplement 1): 2234.
https://doi.org/10.1182/blood-2025-2234
Published: 2025
Journal Articles

Impact of maintenance strategies post-autologous stem cell transplant in patients with newly diagnosed multiple myeloma and high-risk cytogenetic abnormalities

Free
Arvind Suresh, Kwan-Keat Ang, Jodi Lipof, Darren Pan, Anupama Kumar, Shagun Arora, Peter Sayre, Jeffrey Lee Wolf, Thomas Martin, Ajai Chari, Alfred Chung
Journal: Blood
Blood (2025) 146 (Supplement 1): 2805.
https://doi.org/10.1182/blood-2025-2805
Published: 2025
Journal Articles

Impact of low disease burden on the safety and efficacy of BCMA CAR-T in patients with Relapsed/Refractory multiple myeloma

Free
Kevin Reyes, Tanya Jindal, Sireesha Asoori, Chiung-Yu Huang, Darren Pan, Anupama Kumar, Shagun Arora, Alfred Chung, Peter Sayre, Jeffrey Lee Wolf, Ajai Chari, Thomas Martin, Jodi Lipof
Journal: Blood
Blood (2025) 146 (Supplement 1): 2202.
https://doi.org/10.1182/blood-2025-2202
Published: 2025
Journal Articles

Sequential BCMA- and GPRC5D-targeted bispecific antibody therapy in multiple myeloma: Real-world outcomes and first report of dual bispecific antibody-refractory patients

Free
Darren Pan, Jihong Song, Eva Duvalyn, Samantha Shenoy, Chiung-Yu Huang, Anupama Kumar, Jodi Lipof, Alfred Chung, Jeffrey Lee Wolf, Thomas Martin, Shagun Arora, Peter Sayre, Ajai Chari
Journal: Blood
Blood (2025) 146 (Supplement 1): 5760.
https://doi.org/10.1182/blood-2025-5760
Published: 2025
Journal Articles

Impact of prior BCMA-targeted therapy on CAR-T expansion and host T-cell phenotypes in patients with Relapsed/Refractory multiple myeloma receiving BCMA CAR-T therapy

Free
Kevin Reyes, Jodi Lipof, Serena Kwek, Averey Lea, Matthew Clark, Lisa Dunn, Ruixin Sun, Emily Mohler, Jane Greenaway, Darren Pan, Anupama Kumar, Alfred Chung, Peter Sayre, Shagun Arora, Jeffrey Lee Wolf, Thomas Martin, Ajai Chari, David Oh
Journal: Blood
Blood (2025) 146 (Supplement 1): 3916.
https://doi.org/10.1182/blood-2025-3916
Published: 2025
Journal Articles

Outcomes of elderly patients with newly diagnosed multiple myeloma (NDMM): A retrospective comparison of daratumumab-based induction versus autologous stem cell transplant (autoSCT)

Free
Kwan-Keat Ang, Arvind Suresh, Meryl Colton, Anupama Kumar, Darren Pan, Jodi Lipof, Shagun Arora, Alfred Chung, Peter Sayre, Jeffrey Lee Wolf, Thomas Martin, Ajai Chari
Journal: Blood
Blood (2025) 146 (Supplement 1): 6346.
https://doi.org/10.1182/blood-2025-6346
Published: 2025
Journal Articles

Accelerating practical solutions for bispecific antibody consideration for multiple myeloma in the community setting: Findings from an implementation science initiative

Free
Tariqa Ackbarali, Ajai Chari, Hans Lee
Journal: Blood
Blood (2025) 146 (Supplement 1): 2642.
https://doi.org/10.1182/blood-2025-2642
Published: 2025
Journal Articles

Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR T cells

Available to Purchase
Corynn Kasap, Adila Izgutdina, Bonell Patiño-Escobar, Amrik S. Kang, Nikhil Chilakapati, Naomi Akagi, Ananya Manoj, Haley Johnson, Tasfia Rashid, Juwita Werner, Abhilash Barpanda, Huimin Geng, Yu-Hsiu T. Lin, Sham Rampersaud, Daniel Gil-Alós, Amin Sobh, Daphné Dupéré-Richer, Adolfo Aleman, Gianina Wicaksono, K. M. Kawehi Kelii, Radhika Dalal, Emilio Ramos, Anjanaa Vijayanarayanan, Kiran Lakhani, Fernando Salangsang, Paul Phojanakong, Juan Antonio Camara Serrano, Ons Zakraoui, Isa Tariq, Ajai Chari, Alfred Chung, Anupama D. Kumar, Thomas G. Martin, III, Jeffrey Wolf, Sandy W. Wong, Veronica Steri, Mala Shanmugam, Lawrence H. Boise, Tanja Kortemme, Samir Parekh, Elliot Stieglitz, Jonathan D. Licht, William J. Karlon, Benjamin G. Barwick, Arun P. Wiita
Journal: Blood
Blood (2025) 146 (7): 819–833.
https://doi.org/10.1182/blood.2024025536
Published: 2025
Includes: Supplemental data
Journal Articles

Efficacy and safety of daratumumab in intermediate/high-risk smoldering multiple myeloma: final analysis of CENTAURUS

Available to Purchase
Clinical Trials & Observations
Ola Landgren, Ajai Chari, Yael C. Cohen, Andrew Spencer, Peter M. Voorhees, Irwindeep Sandhu, Matthew W. Jenner, Dean Smith, Michele Cavo, Niels W. C. J. van de Donk, Meral Beksac, Philippe Moreau, Hartmut Goldschmidt, Diego Vieyra, Linlin Sha, Liang Li, Els Rousseau, Robyn Dennis, Robin Carson, Craig C. Hofmeister
Journal: Blood
Blood (2025) 145 (15): 1658–1669.
https://doi.org/10.1182/blood.2024025897
Published: 2025
Includes: Supplemental data
Journal Articles

Single-Cell Analysis Reveals Depletion of Antigen-Presenting Cell (APC) and IFN-Stimulated CD4 T Cell Populations in High-Risk Newly Diagnosed Multiple Myeloma Patients

Free
Junia Vieira, Alison S Park, David Melnekoff, Tarek H. Mouhieddine, Alessia D'anna, Adolfo Aleman, Meghana Ram, Katerina Kappes, Mark Hamilton, George Mulligan, Arun P Wiita, Ajai Chari, Thomas Martin, Michael Slade, Li Ding, Ravi Vij, Brian Brown, Benjamin Tycko, Rena Feinman, David S. Siegel, Sundar Jagannath, Samir Parekh, Alessandro Lagana
Journal: Blood
Blood (2024) 144 (Supplement 1): 4654.
https://doi.org/10.1182/blood-2024-208308
Published: 2024
Journal Articles

Feasibility and Implementation of the ASH Research Collaborative's COVID-19 Outcomes in Myeloma and the Impact of Vaccines (COSMIC): A Decentralized, Real-World Evidence Study for Patients with Multiple Myeloma to Monitor Outcomes Related to COVID-19 Vaccines and Infections

Free
William A. Wood, Emily A. Semmel, Shandra James, Donna S. Neuberg, Kathleen Hewitt, Kenneth C. Anderson, Shaji Kumar, Mark A. Schroeder, David J. Chung, Aaron S. Rosenberg, Jeffrey A. Zonder, Samuel M. Rubinstein, Anita D'Souza, Thomas Martin, Ajai Chari, Ravi Vij, Ajay K. Nooka, Brendan M. Weiss, Levi D. Pederson, Andriy Derkach, Susan M. Geyer, Saad Z. Usmani
Journal: Blood
Blood (2024) 144 (Supplement 1): 2393.
https://doi.org/10.1182/blood-2024-203892
Published: 2024
Journal Articles

Minimal Residual Disease Measured after Treatment with Bispecifics in Relapsed Multiple Myeloma: Experience from an Academic Medical Center

Free
Alberto Blanco, Ajai Chari, Thomas G Martin, Shagun Arora, Alfred Chung, Anupama Deepa Kumar, Nina Shah, Sandy W. Wong, Hiroyuki Takamatsu, Joaquin Martínez-López, Jeffrey Lee Wolf
Journal: Blood
Blood (2024) 144 (Supplement 1): 7020.
https://doi.org/10.1182/blood-2024-203768
Published: 2024
Journal Articles

A Phase 2 Study of Daratumumab in Combination with Dose-Attenuated Bortezomib, Lenalidomide, and Dexamethasone in Transplant Ineligible Older Adults with Newly Diagnosed Multiple Myeloma

Free
Larysa J Sanchez, Erin Moshier, Alex Lieberman-Cribbin, Joshua Richter, Shambavi Richard, Adriana Rossi, Cesar Rodriguez, Santiago Thibaud, Hearn Jay Cho, Samir Parekh, Sundar Jagannath, Ajai Chari
Journal: Blood
Blood (2024) 144 (Supplement 1): 7043.
https://doi.org/10.1182/blood-2024-211704
Published: 2024
Journal Articles

Teclistamab, Daratumumab, and Pomalidomide in Patients with Relapsed/Refractory Multiple Myeloma: Results from the Majestec-2 Cohort a and Trimm-2 Studies

Free
Anita D'Souza, Luciano J. Costa, Jesús F. San-Miguel, Jesus G Berdeja, Daniel Morillo Giles, Cyrille Touzeau, John T McKay, Bhagirathbhai Dholaria, Thomas G Martin, Aurore Perrot, Albert Oriol, Anna Sureda Balari, Thomas Prior, Debopriya Ghosh, Lijuan Kang, Julie S Larsen, Hein Ludlage, Lien Vandenberk, Lingling Chen, Bas D Koster, Weili Sun, Rachel Kobos, Emma Searle, Jeffrey V Matous, Ajai Chari, Tobias Kampfenkel
Journal: Blood
Blood (2024) 144 (Supplement 1): 495.
https://doi.org/10.1182/blood-2024-200181
Published: 2024
Journal Articles

Delayed Neurotoxicity after CAR-T in Multiple Myeloma: Results from a Global IMWG Registry

Free
Anupama Deepa Kumar, Suheil Albert Atallah-Yunes, Sridevi Rajeeve, Ahmed Abdelhak, Hamza Hashmi, Andre Corraes, Myo Htut, Paula Rodriguez-Otero, Ricardo D. Parrondo, Saurabh Chhabra, K. Martin Kortüm, Lukas Scheller, Sofie-Katrin Kadel, Hermann Einsele, Niels W.C.J. van de Donk, Jana Mihalyova, Roman Hajek, Joaquin Martinez Lopez, Noa Biran, Carlos Fernández de Larrea, Ingerid Weum Abrahamsen, Szu-Ying Chen, Melissa Ng, Bonell Patino Escobar, Simon J Harrison, Caitlin Costello, Isadora Matos, Edvan Crusoe, Luciano J. Costa, Arun P Wiita, Sasha Gupta, Thomas Martin, Yi Lin, Ajai Chari
Journal: Blood
Blood (2024) 144 (Supplement 1): 4758.
https://doi.org/10.1182/blood-2024-201783
Published: 2024
Journal Articles

Development of the ASH Research Collaborative Multiple Myeloma Program: A Multicenter, Real-World Evidence Generation Network

Free
Shaji Kumar, William A. Wood, Kenneth C. Anderson, Emily A. Semmel, Shandra James, Donna S. Neuberg, Kathleen Hewitt, Mark A. Schroeder, David J. Chung, Aaron S. Rosenberg, Jeffrey A. Zonder, Samuel M. Rubinstein, Anita D'Souza, Thomas Martin, Ajai Chari, Ravi Vij, Ajay K. Nooka, Manisha Bhutani, Peter M. Voorhees, Adam S. Sperling, Susan M. Geyer, Michael W. Craige, Sam Walters, Andriy Derkach, Saad Z. Usmani
Journal: Blood
Blood (2024) 144 (Supplement 1): 3792.5.
https://doi.org/10.1182/blood-2024-210957
Published: 2024
Journal Articles

Late Polyclonal P-BCMA-101 CAR-T Cell Re-Expansion and Rapid Complete Response in a Patient with Relapsed Multiple Myeloma Treated with One Cycle of Talquetamab, More Than 3 Years after CAR-T Infusion

Free
Anupama Deepa Kumar, Ajai Chari, Srishti Gupta, Joseph Rohr, Rajesh Belani, Blair Madison, Zhibo Ma, Chris E Martin, Katherine McArthur, Hilary Ostwald, Syed Rizvi, Thomas G Martin
Journal: Blood
Blood (2024) 144 (Supplement 1): 2083.
https://doi.org/10.1182/blood-2024-211578
Published: 2024