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David S. Siegel
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Journal Articles

Real World Outcomes of Multiple Myeloma Patients Who Underwent Apheresis for Planned Chimeric Antigen Receptor (CAR) T Cell Therapy: A Single Center Experience

Ayrton I Bangolo, Sarvarinder Kaur Gill, Behzad Amoozgar, Shraboni Dey, Ronit Slotky, David S. Siegel, Harsh Parmar, Noa Biran, David H. Vesole, Pooja Phull
Journal: Blood
Blood (2024) 144 (Supplement 1): 7097.
https://doi.org/10.1182/blood-2024-211895
Published: 2024
Journal Articles

Comparative Effectiveness of Linvoseltamab Versus Current Real-World (RW) Standard-of-Care (SOC) Therapies in Triple-Class Exposed Relapsed/Refractory Multiple Myeloma (RRMM): Key Subgroups Analysis

Shaji Kumar, Sundar Jagannath, Katja C. Weisel, Laura Rosiñol Dachs, Meletios-Athanasios Dimopoulos, David S. Siegel, Jorge Monge, Xavier Leleu, Juan Du, Javier de la Rubia, Jae Hoon Lee, María-Victoria Mateos, Borja Puertas Martínez, Alessandro Gozzetti, Dominik Dytfeld, Enrique M. Ocio, Joan Bladé, Shuji Ozaki, Meral Beksac, Fernando Escalante, Madhu Nagaraj, Rafla Hassan, Paul Spin, Nicolle Bonar, Mostafa Shokoohi, Muhaimen Siddiqui, Di Wang, Kevin Hou, Jeannette Green, Olivier Humblet, Alexander Breskin, James Harnett, Wenzhen Ge, Rachel E. Sobel, Jessica J. Jalbert, Glenn S. Kroog, Karen Rodriguez Lorenc, Qiufei Ma, Christian Hampp, Brian G.M. Durie
Journal: Blood
Blood (2024) 144 (Supplement 1): 7012.
https://doi.org/10.1182/blood-2024-200679
Published: 2024
Journal Articles

A Phase 2b Study of Selinexor in Combination with Pomalidomide in Patients with Pomalidomide-Refractory Multiple Myeloma

Noa Biran, David H. Vesole, Harsh Parmar, Pooja Phull, Kimberly R. Doucette, Rena Feinman, Xue Geng, Jaeil Ahn, Joshua Zenreich, Palka Anand, Kristin Ivanovski, Monique Pace, Alexandra Della Pia, Bianca DeAgresta, Lisa Biamonte, Martha Campanaro, Trina McClendon, Samanta BaboolallAracena, Adolfo Aleman, Ella Rutanen, Marie Layton, Genevieve Breeze, Aimee Chappell, Susan Kumka, David S. Siegel
Journal: Blood
Blood (2024) 144 (Supplement 1): 7070.
https://doi.org/10.1182/blood-2024-208473
Published: 2024
Journal Articles

Real World Outcomes with Talquetamab, a T-Cell-Redirecting GPRC5D Bispecific Antibody: A Single Center Experience for Relapsed/ Refractory Multiple Myeloma (RRMM)

Sarvarinder Kaur Gill, Erika Fleming, Helen Gebre, Ayrton I Bangolo, David S. Siegel, David H. Vesole, Noa Biran, Harsh Parmar, Pooja Phull
Journal: Blood
Blood (2024) 144 (Supplement 1): 7047.
https://doi.org/10.1182/blood-2024-210350
Published: 2024
Journal Articles

A Single-Center Experience on the Safety and Efficacy of Venetoclax-Based Regimens in Patients with Relapsed/Refractory Multiple Myeloma

Eli Zolotov, Vanisha Patel, Yedidyah Weiss, Noa Biran, Pooja Phull, David H. Vesole, David S. Siegel, Harsh Parmar
Journal: Blood
Blood (2024) 144 (Supplement 1): 6959.
https://doi.org/10.1182/blood-2024-194740
Published: 2024
Journal Articles

Comparative Effectiveness of Linvoseltamab Versus Current Real-World Standard of Care Therapies in Triple-Class Exposed Relapsed/Refractory Multiple Myeloma Treated at IMWG Sites

Shaji Kumar, Sundar Jagannath, Katja C. Weisel, Laura Rosiñol Dachs, Meletios-Athanasios Dimopoulos, David S. Siegel, Jorge Monge, Xavier Leleu, Juan Du, Javier de la Rubia, Jae Hoon Lee, María-Victoria Mateos, Alessandro Gozzetti, Dominik Dytfeld, Enrique M. Ocio, Joan Bladé, Shuji Ozaki, Madhu Nagaraj, Rafla Hassan, Jeannette Green, Glenn S. Kroog, Karen Rodriguez Lorenc, Christian Hampp, Qiufei Ma, Brian G.M. Durie
Journal: Blood
Blood (2024) 144 (Supplement 1): 7039.
https://doi.org/10.1182/blood-2024-210376
Published: 2024
Journal Articles

Idecabtagene Vicleucel (Ide-cel) in Patients (Pts) with Newly Diagnosed Multiple Myeloma (NDMM) with an Inadequate Response to Front-Line Autologous Stem Cell Transplantation (ASCT): KarMMa-2 Cohort 2c Extended Follow-up

Barry Paul, Madhav V. Dhodapkar, Melissa Alsina, Jesús G. Berdeja, Shambavi Richard, Ravi Vij, Xavier Leleu, Daniel N. Egan, P. Leif Bergsagel, Ran Reshef, Saad Z. Usmani, Anna Truppel-Hartmann, Debashree Basudhar, Ethan G. Thompson, Fan Wu, Laurie Eliason, Soyun Park, Sinhan Tran, Maria Chaudhry, David S. Siegel, Krina K. Patel
Journal: Blood
Blood (2024) 144 (Supplement 1): 3388.
https://doi.org/10.1182/blood-2024-200829
Published: 2024
Journal Articles

Establishing a Distinct Cytokine Signature for Multiple Myeloma Using Bone Marrow RNA and Peripheral Blood Cell-Free RNA (cfRNA)

Maher Albitar, Hong Zhang, Sally Agersborg, Ahmad Charifa, Pooja Phull, Noa Biran, David H. Vesole, Harsh Parmar, Andrew L Pecora, Andrew Ip, Andre Goy, David S. Siegel
Journal: Blood
Blood (2024) 144 (Supplement 1): 3316.
https://doi.org/10.1182/blood-2024-203774
Published: 2024
Journal Articles

Single-Cell Analysis Reveals Depletion of Antigen-Presenting Cell (APC) and IFN-Stimulated CD4 T Cell Populations in High-Risk Newly Diagnosed Multiple Myeloma Patients

Junia Vieira, Alison S Park, David Melnekoff, Tarek H. Mouhieddine, Alessia D'anna, Adolfo Aleman, Meghana Ram, Katerina Kappes, Mark Hamilton, George Mulligan, Arun P Wiita, Ajai Chari, Thomas Martin, Michael Slade, Li Ding, Ravi Vij, Brian Brown, Benjamin Tycko, Rena Feinman, David S. Siegel, Sundar Jagannath, Samir Parekh, Alessandro Lagana
Journal: Blood
Blood (2024) 144 (Supplement 1): 4654.
https://doi.org/10.1182/blood-2024-208308
Published: 2024
Journal Articles

Comparative Efficacy and Safety of Ciltacabtagene Autoleucel and Idecabtagene Vicleucel in Real-World Relapsed/Refractory Multiple Myeloma: A Retrospective Intention-to-Treat Analysis

Behzad Amoozgar, Ayrton I Bangolo, David H. Vesole, David S. Siegel, Noa Biran, Pooja Phull, Michele L. Donato, Harsh Parmar
Journal: Blood
Blood (2024) 144 (Supplement 1): 2408.
https://doi.org/10.1182/blood-2024-211671
Published: 2024
Journal Articles

Repurposing DNA Methyltranferase Inhibitors As Epigenetic Priming Agents for T Cell Directed Therapies in Multiple Myeloma

Rena Feinman, Ariel Aptekmann, Iriana Colorado, Reilly Kobbe, Marta Salas, Noa Biran, David S. Siegel, Benjamin Tycko
Journal: Blood
Blood (2024) 144 (Supplement 1): 1888.
https://doi.org/10.1182/blood-2024-209229
Published: 2024
Journal Articles

Enhanced Prognostic Value of the SKY92 Classifier over High-Risk Cytogenetic Aberrations in Multiple Myeloma: Results from the Prommis Real-World Study

Noa Biran, Binod Dhakal, Ruben Niesvizky, Suzanne Lentzsch, John T Mckay, David H. Vesole, Ajay K. Nooka, Barry Paul, Parameswaran N. Hari, Silvia D'Ambrosi, Rowan Kuiper, Martin H van Vliet, David S. Siegel, Saad Z. Usmani, Frits van Rhee
Journal: Blood
Blood (2024) 144 (Supplement 1): 1929.
https://doi.org/10.1182/blood-2024-209903
Published: 2024
Journal Articles

Clonotype-Naïve Detection of Clonality in Patients Suspected of Having Multiple Myeloma or Monoclonal Gammopathy Using Peripheral Blood Cell-Free RNA (cfRNA)

Maher Albitar, Hong Zhang, Sally Agersborg, Ahmad Charifa, Pooja Phull, Noa Biran, David H. Vesole, Harsh Parmar, Andrew L Pecora, Andrew Ip, Andre Goy, David S. Siegel
Journal: Blood
Blood (2024) 144 (Supplement 1): 1946.
https://doi.org/10.1182/blood-2024-201810
Published: 2024
Journal Articles

First Results from the Dose Escalation Part of the Phase 1 Study of KTX1001, an Oral, First-in-Class, Potent Inhibitor of MMSET/NSD2 for Relapsed/Refractory Multiple Myeloma (RRMM)

Pierre Bories, Cristina Gasparetto, David Dingli, Sagar Lonial, Saad Z. Usmani, Jesus G Berdeja, Alfred Chung, Aimaz Afrough, Laura Rosiñol, Andrew J. Yee, Suzanne Trudel, David S. Siegel, Paula Rodríguez-Otero, Soo Bang, Terry Connolly, Chad A. Lewis, Erin Flynt, Julie Vazquez, Sanjana U. Miskin, Benjamin Winograd, Maria-Victoria Mateos, Cyrille Touzeau, Vivek Roy
Journal: Blood
Blood (2024) 144 (Supplement 1): 3370.
https://doi.org/10.1182/blood-2024-199174
Published: 2024
Journal Articles

A Phase 2b Study of Selinexor in Combination with Carfilzomib, Daratumumab, or Pomalidomide in Patients with Multiple Myeloma Relapsing on Current Therapy

Noa Biran, David H. Vesole, Harsh Parmar, Pooja Phull, Kimberly Doucette, Rena Feinman, Joshua Zenreich, Palka Anand, Kristin Ivanovski, Monique Pace, Lisa Biamonte, Martha Campanaro, Trina McClendon, Chandani Limbad, Samanta BaboolallAracena, Adolfo Aleman, Rashmi Unawane, Elizabeth Pendergrass, Marie Layton, Genevieve Breeze, Aimee Chappell, Alexandra Della Pia, Susan Kumka, David S. Siegel
Journal: Blood
Blood (2023) 142 (Supplement 1): 6714.
https://doi.org/10.1182/blood-2023-187011
Published: 2023
Journal Articles

Sequential Administration of Selinexor and CAR-T Therapy in Relapsed/ Refractory Multiple Myeloma

Sarvarinder Kaur Gill, Noa Biran, Pooja Phull, David H. Vesole, David S. Siegel, Harsh Parmar
Journal: Blood
Blood (2023) 142 (Supplement 1): 6930.
https://doi.org/10.1182/blood-2023-190413
Published: 2023
Journal Articles

Single-Center Experience of Carfilzomib-Based Combinations for Patients with Lymphoplasmacytic Lymphoma

Harsh Parmar, Noa Biran, Pooja Phull, David H. Vesole, David S. Siegel
Journal: Blood
Blood (2023) 142 (Supplement 1): 1684.
https://doi.org/10.1182/blood-2023-190155
Published: 2023
Journal Articles

Teclistamab Demonstrates Clinical Activity in Real-World Patients Ineligible for the Pivotal Majestec-1 Trial

Beth Gordon, Lindsay Fogel, Gaurav Varma, Mateo Mejia Saldarriaga, Jaeil Ahn, Adolfo Aleman, Jessica Caro, Xiaoyi Chen, Jorge Monge, Harsh Parmar, David Kaminetzky, Tibor Moskovits, David S. Siegel, Gareth J. Morgan, Ruben Niesvizky, Noa Biran, Faith E. Davies
Journal: Blood
Blood (2023) 142 (Supplement 1): 4741.
https://doi.org/10.1182/blood-2023-181304
Published: 2023
Journal Articles

Carfilzomib, Daratumumab, and Dexamethasone (KdD) Vs Carfilzomib and Dexamethasone (Kd) for Relapsed/Refractory Multiple Myeloma (RRMM) in the Phase 3 Candor Study: Subgroup Analysis According to Renal Functioning

Meletios Athanasios Dimopoulos, Ola Landgren, David S. Siegel, Sebastian Grosicki, Albert Oriol, Rani Najdi, Chuang Li, Khalid Mezzi, Natalie Shu, Hang Quach
Journal: Blood
Blood (2023) 142 (Supplement 1): 2021.
https://doi.org/10.1182/blood-2023-190726
Published: 2023
Journal Articles

Trial in Progress: A Phase 1 Study of KTX-1001, an Oral, First-in-Class, Selective MMSET Inhibitor in Patients with Relapsed and Refractory Multiple Myeloma

Jesus G. Berdeja, David Dingli, Sagar Lonial, Andrew J. Yee, Alfred Chung, Cristina Gasparetto, P. Leif Bergsagel, Vivek Roy, Al-Ola Abdallah, Sharmilan Thanendrarajan, Aimaz Afrough, Laura Rosiñol, Suzanne Trudel, Paula Rodriguez Otero, Cyrille Touzeau, Pierre Bories, Soo Bang, Terry Connolly, Michelle Kim, Chad A. Lewis, Bao-Van Tran Linberg, M. Travis Quigley, Ola Landgren, Saad Z Usmani, Maria-Victoria Mateos, David S. Siegel
Journal: Blood
Blood (2023) 142 (Supplement 1): 3391.
https://doi.org/10.1182/blood-2023-174550
Published: 2023