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Benjamin Winograd
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Journal Articles

A Mass Cytometry-Based Clinical Pharmacodynamic Assay for Histone 3 Lysine 36 Dimethyl (H3K36me2) Levels in Myeloma Cells and Peripheral Blood for Implementation in NSD2 Inhibitor Ktx-1001 First in Human Trial in Relapsed and Refractory Multiple Myeloma

Joao Lourenco, Erin Flynt, Warren Baker, Edmund Watson, Udo Oppermann, Seyed Alireza Hasheminasab, Vicki Gamble, Benjamin Winograd, Anjan Thakurta
Journal: Blood
Blood (2024) 144 (Supplement 1): 6814.
https://doi.org/10.1182/blood-2024-201554
Published: 2024
Journal Articles

Ktx-1029, a Potent, Selective MMSET/NSD2 Inhibitor Is Effective in t(4;14) Multiple Myeloma Preclinical Models

Erin Flynt, Chad A. Lewis, Benjamin Winograd, Terry Connolly, Lan Xu, Anil Menon
Journal: Blood
Blood (2024) 144 (Supplement 1): 1878.
https://doi.org/10.1182/blood-2024-198468
Published: 2024
Journal Articles

First Results from the Dose Escalation Part of the Phase 1 Study of KTX1001, an Oral, First-in-Class, Potent Inhibitor of MMSET/NSD2 for Relapsed/Refractory Multiple Myeloma (RRMM)

Pierre Bories, Cristina Gasparetto, David Dingli, Sagar Lonial, Saad Z. Usmani, Jesus G Berdeja, Alfred Chung, Aimaz Afrough, Laura Rosiñol, Andrew J. Yee, Suzanne Trudel, David S. Siegel, Paula Rodríguez-Otero, Soo Bang, Terry Connolly, Chad A. Lewis, Erin Flynt, Julie Vazquez, Sanjana U. Miskin, Benjamin Winograd, Maria-Victoria Mateos, Cyrille Touzeau, Vivek Roy
Journal: Blood
Blood (2024) 144 (Supplement 1): 3370.
https://doi.org/10.1182/blood-2024-199174
Published: 2024
Journal Articles

Lava-051, a Novel Bispecific Gamma-Delta T-Cell Engager (Gammabody), in Relapsed/Refractory MM and CLL: Pharmacodynamic and Early Clinical Data

Arnon P. Kater, Niels W.C.J. Van De Donk, Paula Rodríguez-Otero, María Victoria Mateos, Francesc Bosch, Alessandra Tucci, Paolo Ghia, Anton E.P. Adang, Paul W. H.I. Parren, Ilse Tuinhof, Sanjana Umarale, Benjamin Winograd, Hans J. Van Der Vliet, Annemiek Broijl
Journal: Blood
Blood (2022) 140 (Supplement 1): 4608–4609.
https://doi.org/10.1182/blood-2022-166851
Published: 2022
Journal Articles

Bispecific Vγ9Vδ2-T and Type 1 NKT Cell Engager Lava-051 As First-in-Class Clinical Candidate to Target CD1d Expressing CLL, MM and AML

Roeland Lameris, Jurjen M Ruben, Iris de Weerdt, Rob Roovers, Niels W.C.J. van de Donk, Annemiek Broyl, Arnon P. Kater, Thilo Riedl, Victoria Iglesias, Benjamin Winograd, Anton EP Adang, Tanja D. de Gruijl, Paul W. H. I. Parren, Hans J. van der Vliet
Journal: Blood
Blood (2021) 138 (Supplement 1): 2266.
https://doi.org/10.1182/blood-2021-149086
Published: 2021