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Journal Articles

Bispecific Vγ9Vδ2-T and Type 1 NKT Cell Engager Lava-051 As First-in-Class Clinical Candidate to Target CD1d Expressing CLL, MM and AML

Roeland Lameris, Jurjen M Ruben, Iris de Weerdt, Rob Roovers, Niels W.C.J. van de Donk, Annemiek Broyl, Arnon P. Kater, Thilo Riedl, Victoria Iglesias, Benjamin Winograd, Anton EP Adang, Tanja D. de Gruijl, Paul W. H. I. Parren, Hans J. van der Vliet

Blood (2021) 138 (Supplement 1): 2266.

https://doi.org/10.1182/blood-2021-149086

Published: 2021

Journal Articles

Durable Responses and Survival in High Risk AML and MDS Patients Treated with an Allogeneic Leukemia-Derived Dendritic Cell Vaccine

Luca L.G. Janssen, MD, Theresia M. Westers, PhD, Jeroen Rovers, MD PhD, Peter Valk, PhD, Jacqueline Cloos, PhD, Tanja D. de Gruijl, PhD, Arjan A. Van de Loosdrecht, MD PhD

Blood (2019) 134 (Supplement_1): 1381.

https://doi.org/10.1182/blood-2019-127881

Published: 2019

Journal Articles

Improving CLL Vγ9Vδ2-T–cell fitness for cellular therapy by ex vivo activation and ibrutinib

Iris de Weerdt, Tom Hofland, Roeland Lameris, Sanne Endstra, Aldo Jongejan, Perry D. Moerland, Renee C. G. de Bruin, Ester B. M. Remmerswaal, Ineke J. M. ten Berge, Nora Liu, Mario van der Stelt, Laura M. Faber, Mark-David Levin, Eric Eldering, Sanne H. Tonino, Tanja D. de Gruijl, Hans J. van der Vliet, Arnon P. Kater

Blood (2018) 132 (21): 2260–2272.

https://doi.org/10.1182/blood-2017-12-822569

Published: 2018

Includes: Supplemental data

Journal Articles

CD141 Expressing Monocytes Show an Inflammatory Profile and Are Associated with Low-Risk Features in Myelodysplastic Syndromes

Nathalie van Leeuwen-Kerkhoff, MD, Theresia M. Westers, PhD, Shahram Kordasti, MD PhD, Tanja D. de Gruijl, PhD, Arjan A. van de Loosdrecht, MD PhD

Blood (2016) 128 (22): 4298.

https://doi.org/10.1182/blood.V128.22.4298.4298

Published: 2016

Journal Articles

Chronic Lymphocytic Leukemia (CLL) Cells Are Susceptible to γδ-T Cell Mediated Killing, Provided CLL-Derived γδ-T Cell Dysfunction Can be Reversed

Iris de Weerdt, Sanne Terpstra, Tom Hofland, Roeland Lameris, MD, Renee C.G. de Bruin, Mark-David Levin, MDPhD, Ester B.M. Remmerswaal, PhD, Ineke J.M. ten Berge, MD PhD, Sanne H. Tonino, MD PhD, Tanja D de Gruijl, PhD, Hans van der Vliet, MD PhD, Arnon P. Kater, MD PhD

Blood (2015) 126 (23): 2914.

https://doi.org/10.1182/blood.V126.23.2914.2914

Published: 2015

Journal Articles

Dendritic Cell Subsets in Bone Marrow and Peripheral Blood of Patients with Myelodysplastic Syndromes Display Numeric and Functional Defects

Nathalie van Leeuwen-Kerkhoff, MD, Theresia M. Westers, PhD, Hetty J Bontkes, PhD, Shahram Kordasti, MD PhD, Ghulam J. Mufti, MD PhD, Tanja D de Gruijl, PhD, Arjan A van de Loosdrecht, MD PhD

Blood (2015) 126 (23): 4109.

https://doi.org/10.1182/blood.V126.23.4109.4109

Published: 2015

Journal Articles

Clinical and Immunological Results Of a Phase I/IIa Study Of Allogeneic Dendritic Cell (DC) Vaccination, An “off The shelf” Treatment To Prevent Or Delay Relapse In Elderly Patients With Acute Myeloid Leukemia

Arjan A van de Loosdrecht, MD, PhD, Sandra van Wetering, PhD, Saskia Santegoeds, Satwinder Kaur Singh, PhD, Malika Koppes, Anthony Hall, MD, Ada M. Kruisbeek, PhD, Tanja D. de Gruijl, PhD., Gert J. Ossenkoppele, MD PhD

Blood (2013) 122 (21): 2651.

https://doi.org/10.1182/blood.V122.21.2651.2651

Published: 2013

Journal Articles

Notch controls generation and function of human effector CD8 + T cells

Loes M. Kuijk, Marleen I. Verstege, Niels V. Rekers, Sven C. Bruijns, Erik Hooijberg, Bart O. Roep, Tanja D. de Gruijl, Yvette van Kooyk, Wendy W. J. Unger

Blood (2013) 121 (14): 2638–2646.

https://doi.org/10.1182/blood-2012-07-442962

Published: 2013

Includes: Supplemental data

Journal Articles

Response: Breslow thickness and excision interval affect the activation state of Langerhans cells in melanoma sentinel lymph nodes

Mari F. C. M. van den Hout, Bas D. Koster, Berbel J. R. Sluijter, Paul A. M. van Leeuwen, Sybren Meijer, Monique Petrousjka van den Tol, Alfons J. M. van den Eertwegh, Rik J. Scheper, Rieneke van de Ven, Tanja D. de Gruijl

Blood (2012) 119 (20): 4809–4810.

https://doi.org/10.1182/blood-2012-03-413294

Published: 2012

Journal Articles

Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation

Rieneke van de Ven, Mari F. C. M. van den Hout, Jelle J. Lindenberg, Berbel J. R. Sluijter, Paul A. M. van Leeuwen, Sinéad M. Lougheed, Sybren Meijer, M. Petrousjka van den Tol, Rik J. Scheper, Tanja D. de Gruijl

Blood (2011) 118 (9): 2502–2510.

https://doi.org/10.1182/blood-2011-03-344838

Published: 2011

Journal Articles

Apoptotic Blebs From Leukemic Cells as a Source of Tumor Associated Antigen for Monocyte-Derived Dendritic Cell Loading

Jurjen M Ruben, MSc, Hetty J Bontkes, PhD, Theresia M. Westers, PhD, Willemijn van Den Ancker, MSc, Gert J. Ossenkoppele, MD, PhD, Tanja D de Gruijl, PhD, Arjan A. Van de Loosdrecht, MD, PhD

Blood (2010) 116 (21): 3283.

https://doi.org/10.1182/blood.V116.21.3283.3283

Published: 2010

Journal Articles

Expansion of AML Blasts Induces CD14 Expression and Facilitates Leukemic DC Development for Therapeutic Application In AML

Willemijn van den Ancker, Pepijn G.J.T.B. Wijnands, Theresia M. Westers, PhD, Hetty J. Bontkes, PhD, Sandra van Wetering, PhD, Ada M. Kruisbeek, PhD, Gert J. Ossenkoppele, MD, PhD, Tanja D. de Gruijl, PhD., Arjan A. Van de Loosdrecht, MD, PhD

Blood (2010) 116 (21): 2193.

https://doi.org/10.1182/blood.V116.21.2193.2193

Published: 2010

Journal Articles

Functional PRAME Specific T Cells Can Be Cultured From CD8+ Cells From Healthy Donors but Not From Patients at First CR: Implications for Immunotherapeutic Strategies in AML.

Willemijn van den Ancker, Theresia M Westers, PhD, Hetty J Bontkes, PhD, Dewi Wulandari, Erik Hooijberg, PhD, Anita GM Stam, Saskia JAM Santegoets, PhD, Gert J Ossenkoppele, MD, PhD, Tanja D de Gruijl, PhD, Arjan A van de Loosdrecht, MD, PhD

Blood (2009) 114 (22): 4139.

https://doi.org/10.1182/blood.V114.22.4139.4139

Published: 2009

Journal Articles

Maturation by Toll Like Receptor Ligand R848 Improves the Uptake of Apoptotic Leukemic Cells by Monocyte Derived Dendritic Cells.

Willemijn van den Ancker, Theresia M Westers, PhD, Hetty J Bontkes, PhD, Tanja D de Gruijl, PhD, Gert J Ossenkoppele, MD, PhD, Arjan A van de Loosdrecht, MD, PhD

Blood (2009) 114 (22): 2075.

https://doi.org/10.1182/blood.V114.22.2075.2075

Published: 2009

Journal Articles

Comparative Analysis of CD8 + t Cell Priming Efficiencies against a Panel of Leukemia-Associated HLA-A2 Restricted Epitopes Identifies PRAME as a Possible Vaccination Target in AML

Willemijn van den Ancker, Theresia M Westers, PhD, Hetty J Bontkes, PhD, Erik Hooijberg, PhD, Anita GM Stam, Saskia JAM Santegoets, PhD, Gert J Ossenkoppele, MD, PhD, Tanja D de Gruijl, PhD, Arjan A van de Loosdrecht, MD, PhD

Blood (2008) 112 (11): 5441.

https://doi.org/10.1182/blood.V112.11.5441.5441

Published: 2008

Journal Articles

A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration

Rieneke van de Ven, George L. Scheffer, Anneke W. Reurs, Jelle J. Lindenberg, Ruud Oerlemans, Gerrit Jansen, Jean-Pierre Gillet, Joel N. Glasgow, Alexander Pereboev, David T. Curiel, Rik J. Scheper, Tanja D. de Gruijl

Blood (2008) 112 (6): 2353–2359.

https://doi.org/10.1182/blood-2008-03-147850

Published: 2008

Journal Articles

The Novel Bispecific Diabody αCD40/αCD28 Strengthens Leukemic Dendritic Cell Induced T Cell Reactivity.

Ilse Houtenbos, MD, Saskia J.A.M. Santegoets, Theresia M. Westers, PhD, Quinten Waisfisz, PhD, Sergey Kipriyanov, PhD, Fedor Denkers, Rik J. Scheper, Tanja D. de Gruijl, PhD, Gert Ossenkoppele, Arjan A. van Loosdrecht, MD, PhD

Blood (2006) 108 (11): 3710.

https://doi.org/10.1182/blood.V108.11.3710.3710

Published: 2006

Journal Articles

MUTZ-3, a human cell line model for the cytokine-induced differentiation of dendritic cells from CD34 + precursors

Allan J. Masterson, Claudia C. Sombroek, Tanja D. de Gruijl, Yvo M. F. Graus, Hans J. J. van der Vliet, Sinéad M. Lougheed, Alfons J. M. van den Eertwegh, Herbert M. Pinedo, Rik J. Scheper

Blood (2002) 100 (2): 701–703.

https://doi.org/10.1182/blood.V100.2.701

Published: 2002

Journal Articles

Human natural killer T cells acquire a memory-activated phenotype before birth

Hans J. J. van der Vliet, Nobusuke Nishi, Tanja D. de Gruijl, B. Mary E. von Blomberg, Alfons J. M. van den Eertwegh, Herbert M. Pinedo, Giuseppe Giaccone, Rik J. Scheper

Blood (2000) 95 (7): 2440–2442.

https://doi.org/10.1182/blood.V95.7.2440

Published: 2000

NARROW

Bispecific Vγ9Vδ2-T and Type 1 NKT Cell Engager Lava-051 As First-in-Class Clinical Candidate to Target CD1d Expressing CLL, MM and AML

Durable Responses and Survival in High Risk AML and MDS Patients Treated with an Allogeneic Leukemia-Derived Dendritic Cell Vaccine

Improving CLL Vγ9Vδ2-T–cell fitness for cellular therapy by ex vivo activation and ibrutinib

CD141 Expressing Monocytes Show an Inflammatory Profile and Are Associated with Low-Risk Features in Myelodysplastic Syndromes

Chronic Lymphocytic Leukemia (CLL) Cells Are Susceptible to γδ-T Cell Mediated Killing, Provided CLL-Derived γδ-T Cell Dysfunction Can be Reversed

Dendritic Cell Subsets in Bone Marrow and Peripheral Blood of Patients with Myelodysplastic Syndromes Display Numeric and Functional Defects

Clinical and Immunological Results Of a Phase I/IIa Study Of Allogeneic Dendritic Cell (DC) Vaccination, An “off The shelf” Treatment To Prevent Or Delay Relapse In Elderly Patients With Acute Myeloid Leukemia

Notch controls generation and function of human effector CD8 + T cells

Response: Breslow thickness and excision interval affect the activation state of Langerhans cells in melanoma sentinel lymph nodes

Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation

Apoptotic Blebs From Leukemic Cells as a Source of Tumor Associated Antigen for Monocyte-Derived Dendritic Cell Loading

Expansion of AML Blasts Induces CD14 Expression and Facilitates Leukemic DC Development for Therapeutic Application In AML

Functional PRAME Specific T Cells Can Be Cultured From CD8+ Cells From Healthy Donors but Not From Patients at First CR: Implications for Immunotherapeutic Strategies in AML.

Maturation by Toll Like Receptor Ligand R848 Improves the Uptake of Apoptotic Leukemic Cells by Monocyte Derived Dendritic Cells.

Comparative Analysis of CD8 + t Cell Priming Efficiencies against a Panel of Leukemia-Associated HLA-A2 Restricted Epitopes Identifies PRAME as a Possible Vaccination Target in AML

A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration

The Novel Bispecific Diabody αCD40/αCD28 Strengthens Leukemic Dendritic Cell Induced T Cell Reactivity.

MUTZ-3, a human cell line model for the cytokine-induced differentiation of dendritic cells from CD34 + precursors

Human natural killer T cells acquire a memory-activated phenotype before birth

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American Society of Hematology

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ASH Publications

American Society of Hematology

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