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Journal Articles

Measurable residual disease in newly diagnosed multiple myeloma: Experience from a large cohort from an academic medical center

Free
Alberto Blanco, Andrés Arroyo, Ajai Chari, Thomas Martin, Shagun Arora, Alfred Chung, Anupama Kumar, Nina Shah, Joaquin Martinez-Lopez, Jeffrey Lee Wolf
Journal: Blood
Blood (2025) 146 (Supplement 1): 2234.
https://doi.org/10.1182/blood-2025-2234
Published: 2025
Journal Articles

Minimal residual disease dynamics in post-transplant patients with newly diagnosed multiple myeloma who received daratumumab plus lenalidomide versus lenalidomide alone as maintenance therapy in the auriga study

Free
Alfred Chung, Larry Anderson, Laahn Foster, Chakra Chaulagain, Erin M. Pettijohn, Andrew J. Cowan, Caitlin Costello, Sarah Larson, Douglas Sborov, Kenneth Shain, Rebecca Silbermann, Peter Voorhees, Mitul Gandhi, Maria Krevvata, Mai Ngo, Sharmila Patel, Vipin Khare, Annelore Cortoos, Thomas Lin, Ashraf Badros
Journal: Blood
Blood (2025) 146 (Supplement 1): 97.
https://doi.org/10.1182/blood-2025-97
Published: 2025
Journal Articles

Phase 1 study of ktx-1001, a first-in-class oral MMSET/NSD2 inhibitor, demonstrates clinical activity in relapsed/refractory multiple myeloma

Free
Saad Usmani, Pierre Bories, Cristina Gasparetto, David Dingli, Sagar Lonial, David Siegel, Andrew Yee, Cindy Varga, Suzanne Trudel, Laura Rosiñol Dachs, Paula Rodriguez-Otero, Salomon Manier, Jesús Berdeja, Aimaz Afrough, Warren Baker, Seyed Alireza Hasheminasab, Anjan Thakurta, Vinidhra Sridharan, Erin Flynt, Miriam Barnett, Laura Versmee, María-Victoria Mateos, Cyrille Touzeau, Alfred Chung, Vivek Roy, Edward Stadtmauer
Journal: Blood
Blood (2025) 146 (Supplement 1): 250.
https://doi.org/10.1182/blood-2025-250
Published: 2025
Journal Articles

Effectiveness of second-line therapies following upfront daratumumab plus bortezomib, cyclophosphamide and dexamethasone: A new benchmark

Free
Eugene Brailovski, Xia Wu, Grace Gallagher, Mithat Gonen, Andrew Staron, Abhishek Janardan, Vaishali Sanchorawala, Christopher Wanjiku, Sascha Tuchman, Amelia Piteo, Jeffrey Zonder, Alfred Chung, Victor Jimenez-Zepeda, Raymond Comenzo, Heather Landau
Journal: Blood
Blood (2025) 146 (Supplement 1): 5746.
https://doi.org/10.1182/blood-2025-5746
Published: 2025
Journal Articles

Sequential BCMA- and GPRC5D-targeted bispecific antibody therapy in multiple myeloma: Real-world outcomes and first report of dual bispecific antibody-refractory patients

Free
Darren Pan, Jihong Song, Eva Duvalyn, Samantha Shenoy, Chiung-Yu Huang, Anupama Kumar, Jodi Lipof, Alfred Chung, Jeffrey Lee Wolf, Thomas Martin, Shagun Arora, Peter Sayre, Ajai Chari
Journal: Blood
Blood (2025) 146 (Supplement 1): 5760.
https://doi.org/10.1182/blood-2025-5760
Published: 2025
Journal Articles

Impact of prior BCMA-targeted therapy on CAR-T expansion and host T-cell phenotypes in patients with Relapsed/Refractory multiple myeloma receiving BCMA CAR-T therapy

Free
Kevin Reyes, Jodi Lipof, Serena Kwek, Averey Lea, Matthew Clark, Lisa Dunn, Ruixin Sun, Emily Mohler, Jane Greenaway, Darren Pan, Anupama Kumar, Alfred Chung, Peter Sayre, Shagun Arora, Jeffrey Lee Wolf, Thomas Martin, Ajai Chari, David Oh
Journal: Blood
Blood (2025) 146 (Supplement 1): 3916.
https://doi.org/10.1182/blood-2025-3916
Published: 2025
Journal Articles

Correlative biomarker analyses of etentamig in patients with Relapsed/Refractory multiple myeloma (RRMM) at optimal dose support its potential to maximize T-cell activity with rapid and transient proinflammatory cytokine responses

Free
Aarif Ahsan, Christine Mantis, Adam Luo, Pingping Zheng, Wei Liu, Catherine Zhang, Cesar Rodriguez, Peter Voorhees, Anita D'Souza, Alfred Chung, Sascha Tuchman, Hana Safah, John Mckay, Katja Weisel, Raphael Teipel, Neha Korde, Ravi Vij, Shaji Kumar, Muhamed Baljevic, Hira Mian, Rajvineeth Kumar Pothacamury, Anders Svensson, Chetasi Talati, Jeremy Ross
Journal: Blood
Blood (2025) 146 (Supplement 1): 2204.
https://doi.org/10.1182/blood-2025-2204
Published: 2025
Journal Articles

Impact of low disease burden on the safety and efficacy of BCMA CAR-T in patients with Relapsed/Refractory multiple myeloma

Free
Kevin Reyes, Tanya Jindal, Sireesha Asoori, Chiung-Yu Huang, Darren Pan, Anupama Kumar, Shagun Arora, Alfred Chung, Peter Sayre, Jeffrey Lee Wolf, Ajai Chari, Thomas Martin, Jodi Lipof
Journal: Blood
Blood (2025) 146 (Supplement 1): 2202.
https://doi.org/10.1182/blood-2025-2202
Published: 2025
Journal Articles

Impact of maintenance strategies post-autologous stem cell transplant in patients with newly diagnosed multiple myeloma and high-risk cytogenetic abnormalities

Free
Arvind Suresh, Kwan-Keat Ang, Jodi Lipof, Darren Pan, Anupama Kumar, Shagun Arora, Peter Sayre, Jeffrey Lee Wolf, Thomas Martin, Ajai Chari, Alfred Chung
Journal: Blood
Blood (2025) 146 (Supplement 1): 2805.
https://doi.org/10.1182/blood-2025-2805
Published: 2025
Journal Articles

Ultra-sensitive detection of clonal m-protein by mass spectrometry enhances detection of residual disease: Results from A phase 1 study of etentamig monotherapy in patients with relapsed or refractory multiple myeloma

Free
Aarif Ahsan, Adam Luo, Cesar Rodriguez Valdes, Peter Voorhees, Anita D'Souza, Alfred Chung, Sascha Tuchman, Hana Safah, John Mckay, Katja Weisel, Raphael Teipel, Neha Korde, Ravi Vij, Shaji Kumar, Thomas Doerr, Rajvineeth Kumar Pothacamury, Chetasi Talati, Brenda Chyla, Jeremy Ross
Journal: Blood
Blood (2025) 146 (Supplement 1): 5813.
https://doi.org/10.1182/blood-2025-5813
Published: 2025
Journal Articles

Outcomes of elderly patients with newly diagnosed multiple myeloma (NDMM): A retrospective comparison of daratumumab-based induction versus autologous stem cell transplant (autoSCT)

Free
Kwan-Keat Ang, Arvind Suresh, Meryl Colton, Anupama Kumar, Darren Pan, Jodi Lipof, Shagun Arora, Alfred Chung, Peter Sayre, Jeffrey Lee Wolf, Thomas Martin, Ajai Chari
Journal: Blood
Blood (2025) 146 (Supplement 1): 6346.
https://doi.org/10.1182/blood-2025-6346
Published: 2025
Journal Articles

Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR T cells

Available to Purchase
Corynn Kasap, Adila Izgutdina, Bonell Patiño-Escobar, Amrik S. Kang, Nikhil Chilakapati, Naomi Akagi, Ananya Manoj, Haley Johnson, Tasfia Rashid, Juwita Werner, Abhilash Barpanda, Huimin Geng, Yu-Hsiu T. Lin, Sham Rampersaud, Daniel Gil-Alós, Amin Sobh, Daphné Dupéré-Richer, Adolfo Aleman, Gianina Wicaksono, K. M. Kawehi Kelii, Radhika Dalal, Emilio Ramos, Anjanaa Vijayanarayanan, Kiran Lakhani, Fernando Salangsang, Paul Phojanakong, Juan Antonio Camara Serrano, Ons Zakraoui, Isa Tariq, Ajai Chari, Alfred Chung, Anupama D. Kumar, Thomas G. Martin, III, Jeffrey Wolf, Sandy W. Wong, Veronica Steri, Mala Shanmugam, Lawrence H. Boise, Tanja Kortemme, Samir Parekh, Elliot Stieglitz, Jonathan D. Licht, William J. Karlon, Benjamin G. Barwick, Arun P. Wiita
Journal: Blood
Blood (2025) 146 (7): 819–833.
https://doi.org/10.1182/blood.2024025536
Published: 2025
Includes: Supplemental data
Journal Articles

Daratumumab with lenalidomide as maintenance after transplant in newly diagnosed multiple myeloma: the AURIGA study

Free
Clinical Trials & Observations
Ashraf Badros, Laahn Foster, Larry D. Anderson, Jr, Chakra P. Chaulagain, Erin Pettijohn, Andrew J. Cowan, Caitlin Costello, Sarah Larson, Douglas W. Sborov, Kenneth H. Shain, Rebecca Silbermann, Nina Shah, Alfred Chung, Maria Krevvata, Huiling Pei, Sharmila Patel, Vipin Khare, Annelore Cortoos, Robin Carson, Thomas S. Lin, Peter Voorhees
Journal: Blood
Blood (2025) 145 (3): 300–310.
https://doi.org/10.1182/blood.2024025746
Published: 2025
Includes: Supplemental data
Journal Articles

Screening for AL Amyloidosis in Smoldering Multiple Myeloma

Free
Denis Toskic, Mahesh Mansukhani, Ping Zhou, Stephanie Scalia, Xun Ma, Teresa Fogaren, Lisa X. Lee, Alfred Chung, Sascha Alexander Tuchman, Giada Bianchi, Amandeep Godara, Heather J. Landau, Susan Bal, Gurbakhash Kaur, Vaishali Sanchorawala, Gareth Morgan, Hashim Mann, Robert Allen Vescio, Chakra Chaulagain, Cindy Varga, Suzanne Lentzsch, Gheorghe Doros, Raymond Comenzo
Journal: Blood
Blood (2024) 144 (Supplement 1): 6874.
https://doi.org/10.1182/blood-2024-201755
Published: 2024
Journal Articles

First Results from the Dose Escalation Part of the Phase 1 Study of KTX1001, an Oral, First-in-Class, Potent Inhibitor of MMSET/NSD2 for Relapsed/Refractory Multiple Myeloma (RRMM)

Free
Pierre Bories, Cristina Gasparetto, David Dingli, Sagar Lonial, Saad Z. Usmani, Jesus G Berdeja, Alfred Chung, Aimaz Afrough, Laura Rosiñol, Andrew J. Yee, Suzanne Trudel, David S. Siegel, Paula Rodríguez-Otero, Soo Bang, Terry Connolly, Chad A. Lewis, Erin Flynt, Julie Vazquez, Sanjana U. Miskin, Benjamin Winograd, Maria-Victoria Mateos, Cyrille Touzeau, Vivek Roy
Journal: Blood
Blood (2024) 144 (Supplement 1): 3370.
https://doi.org/10.1182/blood-2024-199174
Published: 2024
Journal Articles

Daratumumab Plus Lenalidomide (D-R) Versus Lenalidomide (R) Alone As Maintenance Therapy in Newly Diagnosed Multiple Myeloma (NDMM) after Transplant: Analysis of the Phase 3 Auriga Study Among Clinically Relevant Subgroups

Free
Laahn Foster, Larry D Anderson, Jr., Alfred Chung, Chakra Chaulagain, Erin M. Pettijohn, Andrew J. Cowan, Caitlin Costello, Sarah M. Larson, Douglas W. Sborov, Kenneth H. Shain, Rebecca Silbermann, Peter M. Voorhees, Maria Krevvata, Huiling Pei, Sharmila Patel, Vipin Khare, Annelore Cortoos, Robin Carson, Thomas S. Lin, Ashraf Z. Badros
Journal: Blood
Blood (2024) 144 (Supplement 1): 675.
https://doi.org/10.1182/blood-2024-201736
Published: 2024
Journal Articles

Minimal Residual Disease Measured after Treatment with Bispecifics in Relapsed Multiple Myeloma: Experience from an Academic Medical Center

Free
Alberto Blanco, Ajai Chari, Thomas G Martin, Shagun Arora, Alfred Chung, Anupama Deepa Kumar, Nina Shah, Sandy W. Wong, Hiroyuki Takamatsu, Joaquin Martínez-López, Jeffrey Lee Wolf
Journal: Blood
Blood (2024) 144 (Supplement 1): 7020.
https://doi.org/10.1182/blood-2024-203768
Published: 2024
Journal Articles

Updated Safety and Efficacy Results of Abbv-383, a BCMA x CD3 Bispecific T-Cell Redirecting Antibody, in a First-in-Human Phase 1 Study in Patients with Relapsed/Refractory Multiple Myeloma

Free
Ravi Vij, Shaji Kunnathu Kumar, Anita D'Souza, John T Mckay, Peter M. Voorhees, Alfred Chung, Sascha Alexander Tuchman, Neha Korde, Katja Weisel, Raphael Teipel, Orlando Bueno, Zhongling Feng, Tanya S Rosenberg, Rajvineeth Kumar Pothacamury, Akshanth R Polepally, Shane Lee, Ziyi Jin, Jeremy A Ross, Aarif Ahsan, Chetasi Talati, Cesar Rodriguez
Journal: Blood
Blood (2023) 142 (Supplement 1): 3378.
https://doi.org/10.1182/blood-2023-182388
Published: 2023
Journal Articles

Trial in Progress: A Phase 1 Study of KTX-1001, an Oral, First-in-Class, Selective MMSET Inhibitor in Patients with Relapsed and Refractory Multiple Myeloma

Free
Jesus G. Berdeja, David Dingli, Sagar Lonial, Andrew J. Yee, Alfred Chung, Cristina Gasparetto, P. Leif Bergsagel, Vivek Roy, Al-Ola Abdallah, Sharmilan Thanendrarajan, Aimaz Afrough, Laura Rosiñol, Suzanne Trudel, Paula Rodriguez Otero, Cyrille Touzeau, Pierre Bories, Soo Bang, Terry Connolly, Michelle Kim, Chad A. Lewis, Bao-Van Tran Linberg, M. Travis Quigley, Ola Landgren, Saad Z Usmani, Maria-Victoria Mateos, David S. Siegel
Journal: Blood
Blood (2023) 142 (Supplement 1): 3391.
https://doi.org/10.1182/blood-2023-174550
Published: 2023
Journal Articles

Using Next Generation Sequencing to Identify Trackable Clonotypic Sequences for Minimal Residual Disease Testing in AL Amyloidosis

Free
Xia Wu, Ping Zhou, Sandy W. Wong, Benjamin Rosenthal, Alfred Chung, Denis Toskic, Stephanie Scalia, Raymond Comenzo
Journal: Blood
Blood (2023) 142 (Supplement 1): 3398.
https://doi.org/10.1182/blood-2023-190355
Published: 2023