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Orlando Bueno
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Journal Articles

ABBV-383 Plus Daratumumab-Dexamethasone in Relapsed or Refractory Multiple Myeloma: A Phase 1b Dose-Escalation and Safety Expansion Study

Cesar Rodriguez, Michal Mielnik, Dickran Kazandjian, Wojt Janowski, Michael S.Y. Low, Matthew Pianko, Junichiro Yuda, Carrie Van Der Weyden, Larry D Anderson, Jr., Rahul Banerjee, Laura Rosinol Dachs, Claudio Cerchione, Malin Hultcrantz, Anita D'Souza, Amandeep Godara, Ariel Grajales-Cruz, Ziyi Jin, Akshanth R Polepally, Aarif Ahsan, Shane Lee, Kristin D'Amico, Orlando Bueno, Chetasi Talati, Anders Erik Svensson, Leanne Fleming, Katja C. Weisel, Marek Hus, Peter M. Voorhees
Journal: Blood
Blood (2024) 144 (Supplement 1): 496.
https://doi.org/10.1182/blood-2024-205083
Published: 2024
Journal Articles

Bivalent BCMA Binding and Low Affinity CD3 T-Cell Engagement By Abbv-383 Drives Sustained Activation with Reduced T-Cell Exhaustion in Preclinical Models of Multiple Myeloma

David Sharon, Valerie Robinson, Claudie Hecquet, Kelly Calabrese, Cormac Cosgrove, Christine Mantis, Orlando Bueno, Aarif Ahsan, Adam Chervin, PK Epling-Burnette, Jeremy A Ross
Journal: Blood
Blood (2023) 142 (Supplement 1): 4666.
https://doi.org/10.1182/blood-2023-179039
Published: 2023
Journal Articles

Updated Safety and Efficacy Results of Abbv-383, a BCMA x CD3 Bispecific T-Cell Redirecting Antibody, in a First-in-Human Phase 1 Study in Patients with Relapsed/Refractory Multiple Myeloma

Ravi Vij, Shaji Kunnathu Kumar, Anita D'Souza, John T Mckay, Peter M. Voorhees, Alfred Chung, Sascha Alexander Tuchman, Neha Korde, Katja Weisel, Raphael Teipel, Orlando Bueno, Zhongling Feng, Tanya S Rosenberg, Rajvineeth Kumar Pothacamury, Akshanth R Polepally, Shane Lee, Ziyi Jin, Jeremy A Ross, Aarif Ahsan, Chetasi Talati, Cesar Rodriguez
Journal: Blood
Blood (2023) 142 (Supplement 1): 3378.
https://doi.org/10.1182/blood-2023-182388
Published: 2023
Journal Articles

Venetoclax in Combination with Daratumumab and Dexamethasone Elicits Deep, Durable Responses in Patients with t(11;14) Relapsed/Refractory Multiple Myeloma: Updated Analyses of Minimal Residual Disease Negativity in Phase 1/2 Study

Nizar J Bahlis, Hang Quach, Rachid Baz, Annette J. Vangsted, Shir-Jing Ho, Niels Abildgaard, Jacob Laubach, Vincent Ribrag, Peter M. Voorhees, Xifeng Wang, Orlando Bueno, Yan Luo, Jeremy A Ross, Jonathan L. Kaufman
Journal: Blood
Blood (2023) 142 (Supplement 1): 338.
https://doi.org/10.1182/blood-2023-180766
Published: 2023
Journal Articles

Real-World Evaluation of Outcomes in Relapsed/Refractory Multiple Myeloma Patients That Are Triple-Class Exposed after Receiving 2 or More Prior Lines of Therapy

Katherine Radwanski, Junhua Yu, Kody Pierce, Chetasi Talati, Steve Stricker, Shiyin Jiao, Orlando Bueno
Journal: Blood
Blood (2023) 142 (Supplement 1): 3358.
https://doi.org/10.1182/blood-2023-178824
Published: 2023
Journal Articles

Pharmacokinetics and Immunogenicity of Abbv-383, a B-Cell Maturation Antigen (BCMA) × CD3 Bispecific T-Cell-Redirecting Antibody, in Patients with Relapsed/Refractory Multiple Myeloma (RRMM)

Akshanth R Polepally, Carla Biesdorf, Muhammad Erfan Uddin, Nils Boehm, Jeremy A Ross, Shaji Kunnathu Kumar, Peter M. Voorhees, Anita D'Souza, Katja Weisel, Orlando Bueno, Chetasi Talati, Rajeev M Menon
Journal: Blood
Blood (2023) 142 (Supplement 1): 6722.
https://doi.org/10.1182/blood-2023-180127
Published: 2023
Journal Articles

Phase 2 Study of Venetoclax Plus Carfilzomib and Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma

Luciano J Costa, MD PhD, Edward A. Stadtmauer, MD FACP, Gareth Morgan, MD, Gregory Monohan, MD, Tibor Kovacsovics, MD, Nicholas Burwick, MD, Andrzej Jakubowiak, MD PhD, Jonathan L Kaufman, MD, Mehrdad Mobasher, MD MPH, Kevin J. Freise, PhD, Jeremy A. Ross, PhD, John Pesko, PhD, Wijith Munasinghe, PhD, Saketh Gudipati, MD, Sarah Mudd, PhD, Orlando Bueno, MD PhD, Shaji K. Kumar, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 303.
https://doi.org/10.1182/blood-2018-99-117026
Published: 2018