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Ariel Grajales-Cruz
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Journal Articles

Tumor burden quantified by Soluble B-Cell Maturation Antigen and Metabolic Tumor Volume determine myeloma CAR-T outcomes

Ciara L Freeman, Jerald Noble, Meghan Menges, Ricardo Villanueva, Justyn Y Nakashima, Nicholas B Figura, R. Petter Tonseth, Dietrich Werner Idiaquez, Lawrence Skelson, Eric C Smith, Julieta Abraham-Miranda, Salvatore Corallo, Gabriel De Avila, Omar Castaneda Puglianini, Hien D Liu, Melissa Alsina, Taiga Nishihori, Kenneth H Shain, Rachid C Baz, Brandon J Blue, Ariel Grajales-Cruz, John M. Koomen, Reginald M Atkins, Doris K Hansen, Ariosto Siqueira Silva, Jongphil Kim, Yoganand Balagurunathan, Frederick L Locke
Journal: Blood
Blood blood.2024024965.
https://doi.org/10.1182/blood.2024024965
Published: 2024
Includes: Supplemental data
Journal Articles

The Real-World Safety and Tolerability of Pirtobrutinib Among Patients with B Cell Lymphomas; A Single Center Experience

Mohammad Ammad Ud Din, Katherine Tobon, Julio C. Chavez, Lisa Nodzon, Hayder Saeed, Sameh Gaballa, Ning Dong, Leidy Lismeris Isenalumhe, Celeste M. Bello, Ariel Grajales-Cruz, Kenneth H. Shain, Lubomir Sokol, Bijal D Shah, Javier Pinilla-Ibarz
Journal: Blood
Blood (2024) 144 (Supplement 1): 6778.
https://doi.org/10.1182/blood-2024-208769
Published: 2024
Journal Articles

Activity and Safety of Venetoclax (VEN)-Based Treatment in t(11;14)-Positive Relapsed/Refractory Multiple Myeloma (R/R MM)

Filip Ionescu, Shrinjaya B Thapa, Parth C Patel, Dimitrios Drekolias, Ariosto Siqueira Silva, Praneeth R Sudalagunta, Phaedra Agius, Brandon Blue, Doris K. Hansen, Omar Castaneda, Hien Liu, Jose L. Ochoa-Bayona, Ciara Louise Freeman, Frederick Locke, Taiga Nishihori, Melissa Alsina, Kenneth H. Shain, Rachid Baz, Ariel Grajales-Cruz
Journal: Blood
Blood (2024) 144 (Supplement 1): 4740.
https://doi.org/10.1182/blood-2024-210069
Published: 2024
Journal Articles

Talquetamab Bridging: Paving the Way to B-Cell Maturation Antigen (BCMA) CAR-T Cell Therapy in Relapsed/Refractory Multiple Myeloma (RRMM)

Binod Dhakal, Othman S. Akhtar, Andrew J. Cowan, Shambavi Richard, Reed Friend, Matthew J Rees, Patrick Costello, Mariola Vazquez Martinez, Oren Pasvolsky, Charlotte B Wagner, Alexandria Jensen, James A Davis, Ran Reshef, Danai Dima, Rahul Banerjee, Manisha Bhutani, Omar Nadeem, Ricardo D. Parrondo, Lekha Mikkilineni, Shahzad Raza, Prashant Kapoor, Hitomi Hosoya, Saurabh Chhabra, Ariel Grajales-Cruz, Mahmoud R. Gaballa, Shonali Midha, Melissa Alsina, Douglas W. Sborov, Krina K. Patel, Yi Lin, Christopher J Ferreri, Doris K. Hansen, Luciano J. Costa, Surbhi Sidana
Journal: Blood
Blood (2024) 144 (Supplement 1): 931.
https://doi.org/10.1182/blood-2024-202017
Published: 2024
Journal Articles

Iopofosine I 131 in Previously Treated Patients with Waldenström Macroglobulinemia (WM): Efficacy and Safety Results from the International, Multicenter, Open-Label Phase 2 Study (CLOVER-WaM™)

Sikander Ailawadhi, Maria Gavriatopoulou, Jennifer Peterson, Ioannis Ntanasis-Stathopoulos, Ghassan El-Haddad, Ariel Grajales-Cruz, Aimaz Afrough, Moshe Y. Levy, Judith Trotman, Kimberly R. Doucette, Jorge J. Castillo, Francisco Hernandez-Ilizaliturri, Ajay K. Nooka, Shirley D'Sa, Ralph V. Boccia, Harsh Parmar, Carlos Fernández de Larrea, Guldane Cengiz Seval, Luiza Beatriz Goncalves Beber, Radhakrishnan Ramchandren, Sheeba K. Thomas, Jarrod Longcor, Andrei Shustov, Larry D Anderson, Jr.
Journal: Blood
Blood (2024) 144 (Supplement 1): 861.
https://doi.org/10.1182/blood-2024-200277
Published: 2024
Journal Articles

Clinical Characteristics and Outcomes of Patients with MYD88 Positive Waldenström Macroglobulinemia: A Single Center Retrospective Analysis

Shrinjaya B Thapa, David Kaldas, Jose Laborde, Shrikar Modukuri, Filip Ionescu, Brandon Blue, Julio C. Chavez, Melissa Alsina, Celeste M. Bello, Javier Pinilla-Ibarz, Kenneth H. Shain, Rachid C. Baz, Ariel Grajales-Cruz
Journal: Blood
Blood (2024) 144 (Supplement 1): 3021.
https://doi.org/10.1182/blood-2024-208701
Published: 2024
Journal Articles

Effect of Talquetamab on Responses in Patients with Relapsed and Refractory Multiple Myeloma with Prior Exposure to T-Cell Redirecting Therapies

Omar Castaneda, Doris K. Hansen, Mariola A Vazquez-Martinez, Shrikar Modukuri, Brandon Blue, Julia Fadul, Ariel Denson, Parker Melnick, Filip Ionescu, Kristy Harvey, Blanca Lopez, Katherine Tobon, Hien Liu, Jose L. Ochoa-Bayona, Ciara Louise Freeman, Taiga Nishihori, Kenneth H. Shain, Rachid Baz, Melissa Alsina, Ariel Grajales-Cruz, Allison Graeter, Frederick Locke
Journal: Blood
Blood (2024) 144 (Supplement 1): 5168.
https://doi.org/10.1182/blood-2024-211739
Published: 2024
Journal Articles

Meaningful Change in Patient-Reported Outcomes after CAR T-Cell Therapy for Relapsed/Refractory Multiple Myeloma in Standard of Care: Differences By Race and Ethnicity

Carina E. Ferraris, Xiaoyin Li, Gabriel De Avila, Lisa M. Gudenkauf, Aasha I. Hoogland, Oanh Nguyen, Yvelise Rodriguez, Sylvia L. Crowder, Nathan Parker, Tiffany L. Carson, Rachid C. Baz, Kenneth H. Shain, Brandon Blue, Ariel Grajales-Cruz, Melissa Alsina, Ciara Louise Freeman, Omar Castaneda, Taiga Nishihori, Hien Liu, Frederick L. Locke, Heather S.L. Jim, Doris K. Hansen, Lauren C. Peres, Laura B. Oswald
Journal: Blood
Blood (2024) 144 (Supplement 1): 5165.
https://doi.org/10.1182/blood-2024-208529
Published: 2024
Journal Articles

De Novo Resistance and Relapse from Daratumumab Monotherapy in NDMM Is Associated with Immune Evasion and Immunosuppression

Mark B. Meads, Xiaohong Zhao, David R. Noyes, Alexandra Achille, Praneeth Reddy Sudalagunta, Chaomei H. Zhang, Sonila Toska, Jongphil Kim, Samer Sansil, Sean J. Yoder, Ariel Grajales-Cruz, Brandon Blue, Ciara Louise Freeman, Melissa Alsina, Ariosto Siqueira Silva, Xiaofei Song, Rachid Baz, Kenneth H. Shain
Journal: Blood
Blood (2024) 144 (Supplement 1): 1906.
https://doi.org/10.1182/blood-2024-210232
Published: 2024
Journal Articles

Predictive Markers for Outcomes after Disease Progression Post BCMA-Directed CAR T-Cell Therapy in Patients with Relapsed or Refractory Multiple Myeloma

Fnu Amisha, Ziad Abuhelwa, Wenyi Fan, Doris K. Hansen, Omar Castaneda, Ciara Louise Freeman, Hien Liu, Frederick Locke, Taiga Nishihori, Ariel Grajales-Cruz, Brandon Blue, Kenneth H. Shain, Melissa Alsina, Rachid Baz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2004.
https://doi.org/10.1182/blood-2024-211822
Published: 2024
Journal Articles

Predictors and Characterization of Cytokine Release Syndrome (CRS) and Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) in Patients with Multiple Myeloma Receiving Teclistamab

Oren Pasvolsky, Aimaz Afrough, Lei Feng, Wenli Dong, Tiffany Richards, James A Davis, Danai Dima, Ariel Grajales-Cruz, Mariola A Vazquez-Martinez, Aishwarya Sannareddy, Utkarsh Goel, Rahul Banerjee, Mahmoud R. Gaballa, Alex Lieberman-Cribbin, Masooma S Rana, Kelley Julian, Christopher J Ferreri, Leyla O. Shune, Shaun DeJarnette, Evguenia Ouchveridze, Sandra Susanibar-Adaniya, Andrew J. Portuguese, Peter A. Forsberg, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Adriana Rossi, Megan M Herr, Erin Eberwein, Chenyu Lin, Brandon Blue, Shahzad Raza, Yi Lin, Joseph P. McGuirk, Shebli Atrash, Douglas W Sborov, Peter M. Voorhees, Faiz Anwer, Doris K. Hansen, Krina K. Patel, Surbhi Sidana, Andrew J. Cowan, Larry D Anderson, Jr., Shambavi Richard, Alfred L. Garfall, Hans C. Lee, Jack Khouri
Journal: Blood
Blood (2024) 144 (Supplement 1): 3337.
https://doi.org/10.1182/blood-2024-206357
Published: 2024
Journal Articles

Single-Cell Analysis of CAR-T Cell Products Idecabtagene Vicleucel and Ciltacabtagene Autoleucel Reveals Factors That Influence Clinical Outcomes

Jerald Noble, Xiaofei Song, Meghan Menges, Julieta Abraham-Miranda, Salvatore Corallo, Gabriel De Avila, Omar Puglianini, Hien Liu, Melissa Alsina, Taiga Nishihori, Kenneth H. Shain, Rachid Baz, Brandon Blue, Ariel Grajales-Cruz, Doris K. Hansen, Reginald Atkins, Frederick L. Locke, Ciara Louise Freeman
Journal: Blood
Blood (2024) 144 (Supplement 1): 7173.
https://doi.org/10.1182/blood-2024-208709
Published: 2024
Journal Articles

Outcomes of Teclistamab (Tec) in Patients with Relapsed/Refractory Multiple Myeloma (RRMM) with Prior Exposure to BCMA-Directed Therapy (BCMA-DT): A Multicenter Study from the U.S. Multiple Myeloma Immunotherapy Consortium

Danai Dima, Mariola A Vazquez-Martinez, James A Davis, Utkarsh Goel, Aimaz Afrough, Aishwarya Sannareddy, Oren Pasvolsky, Beatrice Razzo, Rahul Banerjee, Jack Khouri, Ariel Grajales-Cruz, Alex Lieberman-Cribbin, Masooma Shifa Rana, Kelley Julian, Shaun DeJarnette, Andrew J Portuguese, Mahmoud R. Gaballa, Gabriel De Avila, Sandra Susanibar-Adaniya, Shahzad Raza, Megan M Herr, Evguenia Ouchveridze, Tiffany Richards, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Daniel Schrum, Omar Castaneda, Adriana Rossi, Chenyu Lin, Peter A. Forsberg, Yi Lin, Shebli Atrash, Douglas W Sborov, Kenneth H. Shain, Peter M. Voorhees, Shambavi Richard, Alfred L. Garfall, Doris K. Hansen, Surbhi Sidana, Krina K. Patel, Andrew J. Cowan, Larry D Anderson, Jr., Hans C. Lee, Faiz Anwer, Christopher Ferreri, Leyla O. Shune
Journal: Blood
Blood (2024) 144 (Supplement 1): 897.
https://doi.org/10.1182/blood-2024-203409
Published: 2024
Journal Articles

Outcomes of Elderly Patients with Relapsed Refractory Multiple Myeloma (RRMM) Treated with Teclistamab: A Multicenter Study from the U.S. Multiple Myeloma Immunotherapy Consortium

Oren Pasvolsky, Danai Dima, Lei Feng, Wenli Dong, Tiffany Richards, James A Davis, Aimaz Afrough, Mariola A Vazquez-Martinez, Aishwarya Sannareddy, Utkarsh Goel, Rahul Banerjee, Jack Khouri, Frances N. Cervoni Curet, Mahmoud R. Gaballa, Alex Lieberman-Cribbin, Masooma S Rana, Kelley Julian, Christopher J Ferreri, Leyla O. Shune, Shaun DeJarnette, Evguenia Ouchveridze, Sandra Susanibar-Adaniya, Andrew J. Portuguese, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Adriana Rossi, Megan M Herr, Daniel Schrum, Chenyu Lin, Shahzad Raza, Yi Lin, Shebli Atrash, Joseph P. McGuirk, Douglas W Sborov, Peter M. Voorhees, Faiz Anwer, Melissa Alsina, Ciara Louise Freeman, Alfred L. Garfall, Surbhi Sidana, Andrew J. Cowan, Larry D Anderson, Jr., Doris K. Hansen, Shambavi Richard, Krina K. Patel, Hans C. Lee, Ariel Grajales-Cruz
Journal: Blood
Blood (2024) 144 (Supplement 1): 934.
https://doi.org/10.1182/blood-2024-205989
Published: 2024
Journal Articles

Trajectories of Patient-Reported Outcomes after Idecabtagene Vicleucel Vs. Ciltacabtagene Autoleucel CAR T-Cell Therapy Among Patients with Relapsed/Refractory Multiple Myeloma in Standard of Care

Xiaoyin Li, Carina E. Ferraris, Gabriel De Avila, Lisa M. Gudenkauf, Aasha I. Hoogland, Oanh Nguyen, Yvelise Rodriguez, Sylvia L. Crowder, Nathan Parker, Tiffany L. Carson, Rachid C. Baz, Kenneth H. Shain, Brandon Blue, Ariel Grajales-Cruz, Melissa Alsina, Ciara Louise Freeman, Omar Castaneda, Taiga Nishihori, Hien Liu, Frederick L. Locke, Heather S.L. Jim, Doris K. Hansen, Lauren C. Peres, Laura B. Oswald
Journal: Blood
Blood (2024) 144 (Supplement 1): 7842.
https://doi.org/10.1182/blood-2024-208668
Published: 2024
Journal Articles

ABBV-383 Plus Daratumumab-Dexamethasone in Relapsed or Refractory Multiple Myeloma: A Phase 1b Dose-Escalation and Safety Expansion Study

Cesar Rodriguez, Michal Mielnik, Dickran Kazandjian, Wojt Janowski, Michael S.Y. Low, Matthew Pianko, Junichiro Yuda, Carrie Van Der Weyden, Larry D Anderson, Jr., Rahul Banerjee, Laura Rosinol Dachs, Claudio Cerchione, Malin Hultcrantz, Anita D'Souza, Amandeep Godara, Ariel Grajales-Cruz, Ziyi Jin, Akshanth R Polepally, Aarif Ahsan, Shane Lee, Kristin D'Amico, Orlando Bueno, Chetasi Talati, Anders Erik Svensson, Leanne Fleming, Katja C. Weisel, Marek Hus, Peter M. Voorhees
Journal: Blood
Blood (2024) 144 (Supplement 1): 496.
https://doi.org/10.1182/blood-2024-205083
Published: 2024