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Jerald Noble
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Journal Articles

Tumor burden quantified by Soluble B-Cell Maturation Antigen and Metabolic Tumor Volume determine myeloma CAR-T outcomes

Ciara L Freeman, Jerald Noble, Meghan Menges, Ricardo Villanueva, Justyn Y Nakashima, Nicholas B Figura, R. Petter Tonseth, Dietrich Werner Idiaquez, Lawrence Skelson, Eric C Smith, Julieta Abraham-Miranda, Salvatore Corallo, Gabriel De Avila, Omar Castaneda Puglianini, Hien D Liu, Melissa Alsina, Taiga Nishihori, Kenneth H Shain, Rachid C Baz, Brandon J Blue, Ariel Grajales-Cruz, John M. Koomen, Reginald M Atkins, Doris K Hansen, Ariosto Siqueira Silva, Jongphil Kim, Yoganand Balagurunathan, Frederick L Locke
Journal: Blood
Blood blood.2024024965.
https://doi.org/10.1182/blood.2024024965
Published: 2024
Includes: Supplemental data
Journal Articles

Intrinsic Tumor Drivers and Immune Escape Mechanisms in CD19 CAR T-Cell Therapy Resistance for Aggressive Large B Cell Lymphoma

Bachisio Ziccheddu, Michael D. Jain, Monika Chojnacka, Michael Durante, Venu Venkatarame Gowda Saralamma, Austin Daniel Newsam, Jerald Noble, Nicholas B Figura, Meghan Menges, Ola Landgren, Marco Davila, Jonathan H. Schatz, Francesco Maura, Frederick L. Locke
Journal: Blood
Blood (2024) 144 (Supplement 1): 232.
https://doi.org/10.1182/blood-2024-208372
Published: 2024
Journal Articles

Single-Cell Analysis of CAR-T Cell Products Idecabtagene Vicleucel and Ciltacabtagene Autoleucel Reveals Factors That Influence Clinical Outcomes

Jerald Noble, Xiaofei Song, Meghan Menges, Julieta Abraham-Miranda, Salvatore Corallo, Gabriel De Avila, Omar Puglianini, Hien Liu, Melissa Alsina, Taiga Nishihori, Kenneth H. Shain, Rachid Baz, Brandon Blue, Ariel Grajales-Cruz, Doris K. Hansen, Reginald Atkins, Frederick L. Locke, Ciara Louise Freeman
Journal: Blood
Blood (2024) 144 (Supplement 1): 7173.
https://doi.org/10.1182/blood-2024-208709
Published: 2024
Journal Articles

Paired Analysis from Patients with Myeloma Elucidates Favorable CAR-T Manufacture and Phenotype, Starting from Mobilized Pre-Transplant Apheresis Vs. Non-Mobilized Apheresis after Four Prior Lines

Ciara Louise L. Freeman, Julieta Abraham Miranda, Meghan Menges, Jerald Noble, Hien Liu, Salvatore Corallo, Albert J Ribickas, Constanza Savid-Frontera, Gabriel De Avila, Omar Castaneda, Jose L. Ochoa-Bayona, Rachid Baz, Doris K. Hansen, Melissa Alsina, Kenneth H. Shain, Taiga Nishihori, Reginald Atkins, Frederick L. Locke
Journal: Blood
Blood (2023) 142 (Supplement 1): 1931.
https://doi.org/10.1182/blood-2023-187539
Published: 2023
Journal Articles

CD19 Intron Retention Is Mechanism of CAR-T Treatment Resistance in Non-Hodgkin Lymphoma

Jerald Noble, Frederick L. Locke, Constanza Savid-Frontera, Michael D. Jain, Joel G. Turner, Julieta Abraham Miranda, Thushara W Madanayake, Samira Naderinezhad, Salvatore Corallo, Meghan Menges, Kayla Reid, Timothy J Robinson
Journal: Blood
Blood (2023) 142 (Supplement 1): 3506.
https://doi.org/10.1182/blood-2023-185074
Published: 2023
Journal Articles

Expression of Cell Surface Immunotherapy Targets across the Multiple Myeloma Disease Spectrum: Implications for Sequencing and Multi-Target Strategies

Ciara Louise L. Freeman, Meghan Menges, Jerald Noble, Raghunandan Reddy Alugubelli, Rafael Renatino-Canevarolo, Oliver Hampton, Praneeth Reddy Sudalagunta, Salvatore Corallo, Ariosto Siqueira Silva, Mark B Meads, Rachid Baz, Melissa Alsina, Doris K. Hansen, Taiga Nishihori, Omar Castaneda, Brandon Blue, Ariel F. Grajales-Cruz, Yunfei Wang, Patrick Hwu, John Koomen, Kenneth H. Shain, Frederick L. Locke
Journal: Blood
Blood (2023) 142 (Supplement 1): 4678.
https://doi.org/10.1182/blood-2023-185930
Published: 2023
Journal Articles

Single Cell RNA Sequencing of Sequential Samples before and after BCMA-Directed CAR-T Reveal Features Associated with Non-Durable Response, Exhausted T-Cells and Decreased Expression of Genes Encoding Key Surface Targets in Particular in Patients with Extramedullary Disease

Ciara Louise L. Freeman, Xiaohong Zhao, Mark B Meads, Jerald Noble, Raghunandan Reddy Alugubelli, Rafael Renatino-Canevarolo, Oliver Hampton, Praneeth Reddy Sudalagunta, Ariosto Siqueira Silva, Rachid Baz, Melissa Alsina, Doris K. Hansen, Xiaofei Song, Kenneth H. Shain
Journal: Blood
Blood (2023) 142 (Supplement 1): 3304.
https://doi.org/10.1182/blood-2023-191013
Published: 2023
Journal Articles

CAR-T Phenotype and Efficacy Is Impaired By Lymphoma-Associated CD39 + T Cells

Michael D. Jain, Xiaoqing Yu, Reginald Atkins, Joel G. Turner, Jerald Noble, Meghan Menges, Kayla Reid, Salvatore Corallo, Ling Cen, Sean J. Yoder, Julieta Abraham Miranda, Samira Naderinezhad, Hien Liu, Bijal D. Shah, Julio C Chavez, Erin Dean, Johannes Fahrmann, Neeraj Y. Saini, Samir Hanash, Rebecca S. Hesterberg, Paulo C. Rodriguez, John L. Cleveland, Marco Davila, Xuefeng Wang, Frederick L. Locke
Journal: Blood
Blood (2023) 142 (Supplement 1): 3500.
https://doi.org/10.1182/blood-2023-178113
Published: 2023
Journal Articles

Impact of Sarcopenia and Subsequent Muscle Loss on Post-CAR T-Cell Outcomes in Relapsed/Refractory Large B-Cell Lymphoma

Khushali Jhaveri, Ram Thapa, Jerald Noble, Dalia Ercan, Pranit Singh, Johannes Fahrmann, Neeraj Y. Saini, Ranran Wu, Jennifer Dennison, Samir Hanash, Robert R. Jenq, Karnav Modi, Nicholas Figura, Julio C Chavez, Bijal D. Shah, Taiga Nishihori, Aleksandr Lazaryan, Farhad Khimani, Christina A Bachmeier, Kenneth Gage, Asmita Mishra, Fabiana Perna, Marco Davila, Kai Rejeski, Marion Subklewe, Frederick L. Locke, Ciara Louise L. Freeman, Nathan Parker, Michael D. Jain
Journal: Blood
Blood (2023) 142 (Supplement 1): 2130.
https://doi.org/10.1182/blood-2023-187294
Published: 2023