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Reginald Atkins
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Journal Articles

Nfkb signaling in idecabtagene vicleucel infusion product drives response in relapsed/refractory multiple myeloma

Free
Jerald Noble, Barbara Peixoto, Meghan Menges, Julieta Abraham Miranda, Constanza Savid-Frontera, Salvatore Corallo, Emily Merritt, Gabriel De Avila, Omar Alexis Castaneda Puglianini, Hien Liu, Melissa Alsina, Taiga Nishihori, Kenneth Shain, Ariosto Siqueira Silva, Rachid Baz, Brandon Blue, Ariel Grajales-Cruz, Doris Hansen, John Cleveland, Fabiana Perna, Conor Lynch, Jennifer Binning, Reginald Atkins, Frederick Locke, Ciara Louise Freeman
Journal: Blood
Blood (2025) 146 (Supplement 1): 504.
https://doi.org/10.1182/blood-2025-504
Published: 2025
Journal Articles

Humanin-like 8 regulates metabolic fitness and anti-apoptotic programming in CD19 CAR-T cells

Free
Samira Naderinezhad, Jerald Noble, Constanza Savid-Frontera, Bin Fang, Meghan Menges, John Koomen, Reginald Atkins, Frederick Locke
Journal: Blood
Blood (2025) 146 (Supplement 1): 5906.
https://doi.org/10.1182/blood-2025-5906
Published: 2025
Journal Articles

Single-Cell Analysis of CAR-T Cell Products Idecabtagene Vicleucel and Ciltacabtagene Autoleucel Reveals Factors That Influence Clinical Outcomes

Free
Jerald Noble, Xiaofei Song, Meghan Menges, Julieta Abraham-Miranda, Salvatore Corallo, Gabriel De Avila, Omar Puglianini, Hien Liu, Melissa Alsina, Taiga Nishihori, Kenneth H. Shain, Rachid Baz, Brandon Blue, Ariel Grajales-Cruz, Doris K. Hansen, Reginald Atkins, Frederick L. Locke, Ciara Louise Freeman
Journal: Blood
Blood (2024) 144 (Supplement 1): 7173.
https://doi.org/10.1182/blood-2024-208709
Published: 2024
Journal Articles

Paired Analysis from Patients with Myeloma Elucidates Favorable CAR-T Manufacture and Phenotype, Starting from Mobilized Pre-Transplant Apheresis Vs. Non-Mobilized Apheresis after Four Prior Lines

Free
Ciara Louise L. Freeman, Julieta Abraham Miranda, Meghan Menges, Jerald Noble, Hien Liu, Salvatore Corallo, Albert J Ribickas, Constanza Savid-Frontera, Gabriel De Avila, Omar Castaneda, Jose L. Ochoa-Bayona, Rachid Baz, Doris K. Hansen, Melissa Alsina, Kenneth H. Shain, Taiga Nishihori, Reginald Atkins, Frederick L. Locke
Journal: Blood
Blood (2023) 142 (Supplement 1): 1931.
https://doi.org/10.1182/blood-2023-187539
Published: 2023
Journal Articles

CAR-T Phenotype and Efficacy Is Impaired By Lymphoma-Associated CD39 + T Cells

Free
Michael D. Jain, Xiaoqing Yu, Reginald Atkins, Joel G. Turner, Jerald Noble, Meghan Menges, Kayla Reid, Salvatore Corallo, Ling Cen, Sean J. Yoder, Julieta Abraham Miranda, Samira Naderinezhad, Hien Liu, Bijal D. Shah, Julio C Chavez, Erin Dean, Johannes Fahrmann, Neeraj Y. Saini, Samir Hanash, Rebecca S. Hesterberg, Paulo C. Rodriguez, John L. Cleveland, Marco Davila, Xuefeng Wang, Frederick L. Locke
Journal: Blood
Blood (2023) 142 (Supplement 1): 3500.
https://doi.org/10.1182/blood-2023-178113
Published: 2023
Journal Articles

Tumor interferon signaling and suppressive myeloid cells are associated with CAR T-cell failure in large B-cell lymphoma

Free
Michael D. Jain, Hua Zhao, Xuefeng Wang, Reginald Atkins, Meghan Menges, Kayla Reid, Kristen Spitler, Rawan Faramand, Christina Bachmeier, Erin A. Dean, Biwei Cao, Julio C. Chavez, Bijal Shah, Aleksandr Lazaryan, Taiga Nishihori, Mohammed Hussaini, Ricardo J. Gonzalez, John E. Mullinax, Paulo C. Rodriguez, Jose R. Conejo-Garcia, Claudio Anasetti, Marco L. Davila, Frederick L. Locke
Journal: Blood
Blood (2021) 137 (19): 2621–2633.
https://doi.org/10.1182/blood.2020007445
Published: 2021
Includes: Supplemental data
Journal Articles

Tumor Inflammation and Myeloid Derived Suppressor Cells Reduce the Efficacy of CD19 CAR T Cell Therapy in Lymphoma

Free
Michael D. Jain, MD PhD, Hua Zhao, Reginald Atkins, Meghan A Menges, Crystal R Pope, Rawan Faramand, MD, Sae Bom Lee, Justin C. Boucher, PhD, Hiroshi Kotani, MD PhD, Christina A Bachmeier, PharmD, Julio Chavez, Bijal Shah, MD, Mohammad Hussaini, MD, Ricardo J Gonzalez, MD, John E Mullinax, MD PhD, Marco L. Davila, MD PhD, Frederick L. Locke, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2885.
https://doi.org/10.1182/blood-2019-131041
Published: 2019