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Journal Articles

A Novel IL2Rα-/- Model for CAR-T Toxicity in Acute Lymphoblastic Leukemia Recapitulates Cytokine Release Syndrome and Neutropenia

Payal Goala, Hiroshi Kotani, Zhang Yongliang, Kayla M. Reid, Justin C. Boucher, Constanza Savid-Frontera, Sae Bom Lee, Nolan Beatty, Michael D. Jain, Marco L. Davila
Journal: Blood
Blood (2022) 140 (Supplement 1): 1176–1177.
https://doi.org/10.1182/blood-2022-165562
Published: 2022
Journal Articles

Baseline CRP and Ferritin Identify Patients at High Risk of Poor Outcomes after Axicabtagene Ciloleucel Despite Corticosteroid Prophylaxis

Rawan Faramand, Michael D. Jain, Biwei Cao, Xuefeng Wang, Kayla M. Reid, Sae Bom Lee, Salvatore A. Corallo, Meghan A. Menges, Melanie Hidalgo-Vargas, Christina A. Bachmeier, Julio C. Chavez, Bijal D. Shah, Javier Pinilla Ibarz, Aleksandr Lazaryan, Farhad Khimani, Taiga Nishihori, Kelly Speth, Qinghua Song, Mike Mattie, Frederick L. Locke, Marco L. Davila
Journal: Blood
Blood (2022) 140 (Supplement 1): 4678–4680.
https://doi.org/10.1182/blood-2022-171084
Published: 2022
Journal Articles

Tumor Inflammation and Myeloid Derived Suppressor Cells Reduce the Efficacy of CD19 CAR T Cell Therapy in Lymphoma

Michael D. Jain, MD PhD, Hua Zhao, Reginald Atkins, Meghan A Menges, Crystal R Pope, Rawan Faramand, MD, Sae Bom Lee, Justin C. Boucher, PhD, Hiroshi Kotani, MD PhD, Christina A Bachmeier, PharmD, Julio Chavez, Bijal Shah, MD, Mohammad Hussaini, MD, Ricardo J Gonzalez, MD, John E Mullinax, MD PhD, Marco L. Davila, MD PhD, Frederick L. Locke, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2885.
https://doi.org/10.1182/blood-2019-131041
Published: 2019
Journal Articles

Mutation of the CD28 Co-Stimulatory Domain Confers Enhanced CAR T Cell Function

Justin C. Boucher, PhD, Gongbo Li, PhD MBBS, Hiroshi Kotani, MD PhD, Maria Cabral, Dylan Morrissey, Sae Bom Lee, Kristen Spitler, Nolan Beatty, Bishwas Shrestha, PhD, Bin Yu, Aslamuzzaman Kazi, Xuefeng Wang, PhD, Said Sebti, PhD, Marco L. Davila, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 248.
https://doi.org/10.1182/blood-2019-122954
Published: 2019
Journal Articles

The Lymphoma Tumor Microenvironment Influences Toxicity after CD19 CAR T Cell Therapy

Michael D. Jain, MD PhD, Rawan Faramand, MD, Verena Staedtke, MD PhD, Renyuan Bai, MBBS, Sae Bom Lee, Hiroshi Kotani, MD PhD, Kayla Reid, Kristen Spitler, Julio Chavez, Bijal Shah, MD, Christina A Bachmeier, PharmD, Marian Dam, ARNP, Brigett Brandjes, PA, Ricardo J Gonzalez, MD, John E Mullinax, MD PhD, Xuefeng Wang, PhD, Mohammad Hussaini, MD, Frederick L. Locke, MD, Marco L. Davila, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4105.
https://doi.org/10.1182/blood-2019-127305
Published: 2019
Journal Articles

MDSC Suppression of CAR T Cells Can be Reduced By Targeted Signaling Disruption

Estelle V Cervantes, Justin C. Boucher, PhD, Sae Bom Lee, Kristen Spitler, Kayla Reid, Marco L. Davila, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4438.
https://doi.org/10.1182/blood-2019-122752
Published: 2019